Myotis myotis (greater mouse-eared bat): 118666934
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Entry
118666934 CDS
T07220
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
mmyo
Myotis myotis (greater mouse-eared bat)
Pathway
mmyo05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
mmyo00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
118666934 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
mmyo03021
]
118666934 (SETX)
Enzymes [BR:
mmyo01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
118666934 (SETX)
5.6.2.5 RNA 5'-3' helicase
118666934 (SETX)
Transcription machinery [BR:
mmyo03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
118666934 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
AAA_22
ResIII
SLFN-g3_helicase
NAT10_TcmA_helicase
nSTAND3
AAA_16
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
118666934
NCBI-ProteinID:
XP_036185160
LinkDB
All DBs
Position
Unknown
AA seq
2676 aa
AA seq
DB search
MSENPHPGISTERLTSLSRYRMSTCCWCTPGGVSAIEFLQRYASRTQSSEFQTADEDLCY
CLECVTEYHKARDELPFLHEVLWELETLRLINHFEKSMKAEMEGDDDELYIIDNNGEAQP
FDFTGQDFENKLRVPLLEILKYPYLLLHEHVNELCVEALCRMEQANCSFQVFEKQPGIYL
FLVHPNEMVRRWAILTAKGLGKVDRDDYYDLQEVLTCLFKVIELGLLENTDIYTTTVLEK
GKLIILPPHMYDTSNYKNYWLGICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMKRQS
EDDSEDPFWPALHCFMVILDRLGSKVWGQLIDPIEAFQTIIDNASYNREIQNIRNSSVRA
KSEPESCLDDLVTCSQIVYNYNPEKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDIG
QDMRVHNSTFLWFIPFVQSLMDLNDLGMAYIVEVIHHLYSQVKDVLNQTAVVCDKVTEFF
FLILVSVIELHRNKKCLHLLWVSSQQWVEAIVKCAKLPTTAFARNSEKSSANGSKGAAMI
TSLSLHSMPSNSVQFACVQLIRSLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTS
QETHELQTCLKQIIRNIRLKMPQYTALAELAPPCKTPPASNGKEESEQIGKACEKDIPCL
ESCSPTCSKEPVKADVCQVQESSVVSKASNTIEEGNEQNYIKGLKLEDHLSAESHLKQSS
KNLSTERTQDQVKIHTKKQKSVKDNSSCLPQNCTSRNDPEEGCDSGVTMSTHLLTDSNTD
SLEKAPTSKEDFSLKNDVLGKTSKAKTKAQKSDICTELPHVIKKQNRKSALVKNTVDLEG
DLTVSDRENFCSGTDTAGQKGDGFMQNFSLDPNDSLCHKNGQKSLNSLLLKQLKNEELDV
LSSHENDCQVQECHVDNKDFISFTSMPKTSPCKDPVTLLGSSDKGINKSTGPVSSDLREQ
APSSPQCDTLTDSQIDRDLHTLSLIAQARVNKFPSDATQKSSSRLQRKVKDKRSFRANQH
NVRETCERIIIISDSDEDGDEQTPDSEKHIKQDKMCIEKEWPGQGTSIANMNVDMKLTKE
EKIEEFEDSGSQVFEFESQQKVFSVWQDQKTDNGNSVQEDEKNSCLIHIVDITNDWGYDT
DYAMSEEVTKNEAEGTEHAKPQSGSSVEEVCEIKGKKPKRKQFKKMMAEDSLRLSSSVRN
EDQSDTLNERDLTENDTKVADIRTSPNSGVERVTPVSLKKSSPKHRAYSKVDRRASVSKT
PKKTHSDTKKRQNKGLNYISCRNTPAIVLPKKFRQCPEPTSKAEKLGLKKAPRRAAVLSQ
RSLDIIGQLRHHGKIVGEIGTPKKAKLISPRTLPGNDKKLLVSQELPFQRQRRSKSHRNR
QGRNGSAGTTGAAPPAAQHSDSVTPATGRSGNSNKGGAEVLAHSSGAQSVQCVSPEQGPG
KEEYVAQVAGDAFLLSPCSSPVLNGRVPTGAITGCTPEDPLGGGSLTGHHLEVPALKRGQ
LDSDSDMEDDIFLTQHDPEDMDLCSQMQNGDNRLIGEGHWKRVHVEDSINRPQSESLRST
RCKYKDCVETVKSQGECCSKHSEAKAADEDVFRKPALPLSASKPLRPSTTKIFSSSSTSR
IAHLSKSLESASASPGLKNKSNGGQPVSKVPQPASPLSPKPRAEVNSLYNIPHSPIPNNS
SRQAFKLPFGECRPFSSPANIFSSSQPISDTFIKEVLKWKYEMFAKFDQCGPPTTLCQAI
SRSVPVRFQDYKDYFSVFFPLVLLNAFETVAQEWISSPNRGKFYELQLRKFPAEYKKYWE
FVISLEECELSKQLYPRENDLVFLVPERLKGEKREMEGNSIQASHEYHCAYVQRFRRTSV
MHNGKYECSLFIQTEDKFPVNVNETVRCVVISSLVTTQRKLKAMSLLNSRNQLARAILNP
NPMDFCTTSLLTTTSEGITAYLRDFNDDQKKAIETAYAMVKHSPAVAKICLIHGPPGTGK
SKTIVGLLYRLLTERRGQLDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKERCKDK
KNPLGNCGDINLVRLGPEKSINNEVLRFSLDNQVNHRIMKKDLPYVQEMHRRKEHLDHQL
DELSRQRALSRYGRGIQRQELDEKIAQVSKERQELASKIKEVQGRPQKTQSNIILESHII
CCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQACEVETLTPLIHRCNKLILVGDPKQL
PPTVISLTAQDYGYEQSMMARFCKLLEENVEHLVSGRLPVLQLTVQYRMHPDICLFPSNY
IYNKSLKTNRGTESARCSSSWPFQPYLVFDVGDGSERRENDSYVNIQEIKVVMELIKLLR
DKGRDVNFRNVGIITHYKAQKMKILKELDKEFEGRGLAEVDTVDAFQGRQKDCIIVTCVR
ANAIQGSIGFLASLQRLNVAITRAKYSLFILGHLRTLMDNQHWNHLIQDAQRRGAIVKTC
DKNYKQDAMKILKLKSVLQRSLTYPPSAAPEGSSPQGGSPGSDQNRTLLGDSLYRASVDA
KEAADSVAGKDLERPPVKDQLRDPRLLRRMSISAEAPGNCPRDPEPRDPQHSEAAPPLGV
PGFPVSPRTLDRALKLCLATWSSHRAHVPCEPPGASIDSTNESDQQGGHSHQREARAVSD
RDQEMPSPGNHHPKRSSSWDDGRAEEEDSGSKKRKL
NT seq
8031 nt
NT seq
+upstream
nt +downstream
nt
atgagtgaaaatcctcacccaggaatctcgactgagaggctcacatctctatccaggtac
agaatgagcacatgttgctggtgtacgccaggtggcgtttccgccattgagttcctacag
cgctatgcatccaggacccagtccagtgaattccagacagcagatgaagacctctgctac
tgcttagagtgtgtgactgagtaccacaaagcaagggacgagctgccattcttgcatgag
gttttatgggaattagaaaccttacgtctcataaatcactttgaaaaatctatgaaagca
gaaatggaaggtgatgatgatgaattatatatcatagacaacaatggagaggcacaaccg
tttgacttcactggccaagactttgagaataagcttcgagttcctcttctcgaaatcctg
aaatacccttatctgcttttacatgagcatgttaatgagttatgtgttgaagcactttgt
cggatggaacaagccaattgctcctttcaggtttttgagaaacagcccggaatctatttg
tttttggtccatcccaacgaaatggttcgtcgttgggctatcctgactgcaaaaggcttg
ggaaaagtggacagggatgattattacgacttacaagaggttttgacttgcctttttaaa
gtcattgagttggggcttttagaaaatacagacatttatactactactgtccttgagaag
ggtaaattgatcatcctgcctccacacatgtatgacacttccaactacaaaaactattgg
ttaggaatttgcatgctgctgaccattctcgaggagcaagccatggattcactgttgttg
ggctcagacaaacagaatgatttcatgcagtcaatacttcacaccatgaagagacagtca
gaggatgatagtgaagatcctttctggccagcattgcactgtttcatggtcattttggat
cgcctgggatctaaggtctggggtcaacttattgatcctattgaggcctttcagaccatt
atcgacaatgcaagctacaacagagagatccagaatatacggaacagctctgtgagggcc
aagtcagaaccagagtcgtgtctggatgatttggtgacttgcagccagattgtgtacaat
tataaccctgaaaagaccaaaaaggattcagggtggagatcagccatttgcccagattat
tgtcctaacatgtatgaagaaatggaaacattagccagtgtgcttcagtcagatattggt
caagacatgcgtgttcacaacagcacatttctgtggttcatcccttttgttcagtccctc
atggatcttaatgatttgggtatggcttacatagtagaggtcatccaccatctgtactcc
caagtcaaagatgttctcaaccaaacagctgtggtgtgtgacaaagtcactgaatttttt
ttcctaattttggtgtcggtgattgaactacatagaaataaaaaatgtttgcatttgctg
tgggttagctcccagcagtgggtagaagccattgtgaaatgtgccaagcttcccaccact
gcatttgcacggaattctgagaagtcatctgccaatggctccaaaggagcagcaatgata
acgtctctgtcactgcattcaatgccatctaactctgtacagttcgcttgtgtgcagctc
attagaagtcttcttaaagaaggttatcagcttgggcagcagactctttgtaagcgattc
tgggataagctcaacttattcctgcgaggaaatttatctctaggttggcagttgactagt
caggaaacccacgagttacaaacttgtttaaagcaaattattagaaacataagattgaaa
atgcctcaatatactgctttggcagagttggctcctccatgtaaaacccctcctgcctct
aatggtaaagaagaaagtgagcaaatagggaaggcatgtgaaaaagacatcccctgtctg
gaaagttgcagcccaacgtgttctaaagaaccagtgaaagctgatgtatgtcaagtgcaa
gagagtagtgtagtaagcaaagcaagtaacactatagaagaaggtaatgagcaaaattat
ataaaaggtttgaaactagaagaccatctctcagctgagtcacacttaaagcagagtagt
aaaaacctttccactgaaagaacccaagatcaagttaaaatacacacaaagaagcagaag
tctgtaaaagataattcctcctgtttgccacagaactgtacttcaagaaatgatccagaa
gagggatgtgacagtggagtaactatgtcaacacatttgttgactgattctaacactgat
tctctggaaaaggcacccacatcaaaagaggatttctctctaaagaatgatgttcttggc
aaaacctcaaaagcaaaaactaaggcacagaaaagtgacatttgtactgagttaccccat
gtaataaagaagcaaaacaggaaaagtgccttggtcaaaaatactgtggacttagaggga
gacctgactgtctctgaccgtgagaatttctgttcagggacagatactgcaggtcagaaa
ggtgatggcttcatgcagaacttttctttagaccctaatgatagtctgtgtcataaaaat
ggacagaaatctcttaacagtttattgctgaaacagttgaagaatgaagagttagacgtt
ctttcttcccatgaaaacgattgtcaagtacaggaatgtcatgttgataataaagatttt
atctcatttacttccatgcctaaaacatctccctgtaaagatcctgtgactttacttgga
tcaagtgataaggggattaacaagagcactggtccagtttcttctgacctgagagaacag
gcccctagcagtcctcagtgtgacaccctaacagattctcagatagacagagacctccac
acattatctttaatagctcaagcccgtgtcaataagtttccatcagatgcaacccaaaaa
agctcatcccggttacaaagaaaagtaaaagataaaagaagtttcagagccaaccaacat
aatgtcagggaaacctgtgaacgaattattattatttcagattctgatgaagatggtgat
gaacaaactccagattctgagaaacacattaaacaagataaaatgtgcattgagaaagaa
tggccagggcagggtacttcaatagctaatatgaatgtggacatgaagctaacaaaggaa
gagaagatagaggagtttgaggactctggctctcaggtttttgagtttgaaagccaacag
aaagtgttttcagtttggcaagatcagaaaacagacaatgggaattcagttcaagaggat
gaaaaaaattcatgtttgattcatatagtagatatcacaaacgattggggttatgataca
gattacgctatgtctgaagaagttaccaaaaatgaagcagagggcactgagcatgcaaaa
ccacaaagtggtagttctgttgaggaagtttgtgaaattaaaggaaaaaaacccaagaga
aaacaatttaaaaaaatgatggctgaagactctttaaggctttcatcttctgtcagaaat
gaggaccaatctgatactcttaatgagagggatctaactgaaaatgatactaaagttgca
gacataagaacatctcccaattcaggtgttgagagagtcactccggtctccctgaagaag
tcatctccaaagcatcgagcttactccaaagtggatcggagagcctccgtttctaaaaca
cctaagaaaacgcattcagacaccaaaaaaaggcagaataaaggtttaaattacataagt
tgcaggaacactcctgctatcgtgctaccaaagaaatttcgccagtgtcctgaaccaact
tcaaaggctgagaaacttggtctgaaaaaggctcctcgtcgagcagctgtgttgtctcag
cgatctttagacataataggtcaattacgccaccatggcaaaattgttggagaaattggt
accccaaaaaaggctaaactaatttctcctcggactcttcctgggaacgataagaaactg
ctcgtgagtcaagagcttccatttcaaaggcagaggagatccaaatctcatcgaaacaga
caaggacggaatggcagtgcaggcactacaggagcagcaccacctgcggcccagcattcc
gacagtgttacaccggctacaggtaggtcaggcaacagtaacaaaggaggagctgaggtc
ctggcacacagtagtggagctcagtcagtacaatgtgtgtctcctgagcaaggacctggg
aaagaagaatacgttgctcaggtggctggtgatgcttttcttttgagcccttgtagttcc
cctgtgttaaatggaagggtaccaacaggtgcaattacgggctgtactccagaggacccg
ttaggtggtggcagcctgactggacatcatttagaggtgccagctttgaaaaggggacag
cttgactccgacagtgatatggaagatgatatctttttaacacaacatgatcccgaagat
atggacttatgttcacaaatgcagaatggtgataatagactcattggagaaggccattgg
aaaagagttcatgtagaagattctataaatcggcctcagtcagaatctttgcgtagcaca
agatgtaagtacaaggattgtgtggaaactgtgaaaagccagggtgagtgctgctcaaaa
cactctgaagctaaagcagcagatgaagatgtctttcgtaaacctgccctgcctctttct
gcgtctaaacctttgagaccttccaccacaaagatttttagctcaagcagtacttcacga
attgctcatctttccaagtctttggaaagtgcctcggcatctccaggcctaaaaaataag
tcaaatggaggacagcctgtttccaaagtaccacagcctgcctctccgttgtctccaaag
ccaagggctgaagtgaacagtttgtacaatattcctcattctccaattccaaataactcc
agcaggcaagctttcaaactcccgtttggtgagtgcagacctttttcttctccagccaac
attttctcatcatcacagcctatctctgacaccttcatcaaagaggtcttgaaatggaaa
tatgagatgtttgcaaagtttgaccagtgtgggcccccaacaactctttgtcaggccatc
tcaagatccgtgcctgtcagatttcaagattataaagattacttcagtgttttcttccct
ctggtgttactgaatgcctttgaaacggtagcacaggaatggatcagctctccaaacaga
ggaaaattctatgagttgcagttacgaaaatttcctgcagaatataaaaaatactgggag
tttgtgatttctcttgaggaatgtgaactgtctaaacagctttatccaagggagaatgac
ttggtgtttttggttcctgagagactgaaaggagagaagagagagatggaggggaattcc
atccaagcttcccatgaatatcactgtgcttatgttcagagattccgccgcacttcagtc
atgcataatgggaaatatgagtgttcccttttcatccagacggaggataaattcccagtc
aatgtaaatgaaaccgtgagatgtgttgtaatcagttctctggtaactacacaaaggaag
ttgaaagcaatgtctttgttgaatagtcgaaaccaactggccagagctattctgaatcca
aaccccatggacttctgtacaacaagtctactaactacaacatctgagggaattactgcc
tacttaagggatttcaatgacgaccagaagaaagcgatagaaactgcgtatgccatggtg
aaacactccccggcggtggccaagatctgtctgattcatgggccacctggaacagggaaa
tcaaaaaccatcgttggcctcctgtaccgcctgctgacggagaggagggggcagttggat
gaaaactccaacgccaagatcaagcagaaccgcgtgcttgtgtgtgcgccttccaacgca
gccgtggatgagctgatgaaaaaaatcatccttgaattcaaagaaaggtgtaaagacaag
aaaaatcctctgggaaactgtggagatatcaatttagtacgtctgggtccagaaaagtct
attaataatgaggtcctaagattcagtttggacaaccaagttaaccacagaataatgaaa
aaagacttaccttacgttcaggagatgcatagaaggaaggaacatctagaccatcaacta
gatgaactttcccgccagcgtgctttaagccgatatggaagaggaatccagaggcaagaa
ttagatgaaaaaattgcccaagtttcaaaagaaaggcaggaacttgcgtctaaaattaaa
gaggttcaagggcgcccacagaaaacccagagcaacatcatcctagagtcccacatcatc
tgctgcaccctgagcacgagcggcggtttactgctcgagtccgctttccgggggcaaggc
ggggtccccttcagctgtgtcatcgttgacgaggccgggcaggcttgtgaagtggaaacc
cttacccccctcatccaccgctgcaacaagctaatcctcgtcggagacccgaagcagctc
ccccccacagtcatctccttgacggcgcaggactacggctacgagcagtcgatgatggcc
cgcttctgcaagctgctggaggagaacgtggagcacctcgtgagcggcaggctgccggtg
ctccagctgaccgtgcagtacaggatgcacccagacatctgtctcttcccctccaattac
atttacaacaagagcctgaaaaccaacagagggaccgagagcgcgcggtgttcgtccagc
tggccgttccagccttacctcgtgtttgacgtcggggacggctcagaacgacgggagaat
gactcatatgtaaacattcaagaaatcaaagtggtgatggaattgattaaacttctcaga
gacaaaggaagggatgttaatttccggaacgttggcatcatcacccattacaaggctcag
aagatgaagattctgaaggagttggacaaagaatttgaaggaagagggctagcagaagta
gatactgtggatgcatttcagggtcgtcagaaagactgtattattgttacatgtgtcaga
gcaaacgccatacaaggctcaatcggattcctggcgagtttgcagaggttgaacgtcgcc
attacacgagccaagtacagcctcttcatccttgggcatctgaggaccctgatggacaat
cagcattggaaccacctgattcaggatgcgcagaggcgtggcgccatcgtcaagacctgc
gacaagaactataagcaggacgccatgaagatcctgaagctcaagtcggtgctgcagcgg
agtctgacctaccctccttctgcggcccctgagggctccagcccccagggcggctcgccg
ggcagcgaccagaacaggacattgctgggtgactccctgtaccgcgcatccgtggacgct
aaggaggctgctgatagtgttgctggaaaggatcttgaacggcctcctgttaaggaccag
cttcgggacccacgactgctcaggagaatgagcataagcgctgaagccccagggaactgc
ccaagggacccagagccccgggacccccagcattctgaagcagcgccccccttaggagtc
cccggcttccctgtgagtccccggactctggaccgcgccttgaagctgtgcctggccaca
tggagcagccacagagctcacgtgccgtgtgaacctcctggcgccagcattgactccaca
aatgaaagtgaccagcaagggggtcacagccaccagagagaggccagggctgtcagtgac
agggaccaggagatgcccagccctgggaaccatcaccccaagaggagctccagctgggac
gatgggagagccgaggaggaggacagcggctcaaagaagaggaagctgtag
DBGET
integrated database retrieval system
