Myotis myotis (greater mouse-eared bat): 118667030
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Entry
118667030 CDS
T07220
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
mmyo
Myotis myotis (greater mouse-eared bat)
Pathway
mmyo00790
Folate biosynthesis
mmyo01100
Metabolic pathways
mmyo01240
Biosynthesis of cofactors
mmyo01523
Antifolate resistance
mmyo04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
mmyo00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
118667030 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
118667030 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
118667030 (FPGS)
Enzymes [BR:
mmyo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
118667030 (FPGS)
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Paralog
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
118667030
NCBI-ProteinID:
XP_036185473
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Position
Unknown
AA seq
602 aa
AA seq
DB search
MSRARSHRRAGLFLAAVFPRGVTTRVTGRRELSARPAPQEPGMEYQDAVRTLNSLQTNAS
YLAEVKRRRGDLQTQLETMKLYLARSGLQVEDLDQLNIIHVTGTKGKGSTCAFTERILRN
YGLKTGFFRSPGSSPHLVQVRERIRINGQPISPEHFTKHFWRLYHRLEETKDSSSCVSMP
AYFRFLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDT
MEKIAWQKGGIFKVIGQPQGGEHGVPAFTVPQPDGPLAVLRERAEQISCPLYLCPPLEAL
EEGEPPLTLGLEGEHQRANAALALQLARCWLQRKDHQGIGELKASRPSLLCQLPLAPVFQ
PTSHMRHGLRDTEWPGRTQTLRRGPLTWYLDGAHTSSSVQACVRWFRQALHRRPKSGPEV
PEVRVLLFNSTGDRDPAPLLKLLRPCQFDYAVFCPNLTEVSSTDNADQQNFMVTLDQVLL
RCLEHQQHWSRLDEEAASPDLWSTPGPEAGGPASLLLAPRLPHAHGTSSLVFSCISHALQ
WISQGRDPDLQTPSSPRDLLAHPVASSGASVLREAAAVHVLVTGSLHLVGGVLKLLDPSL
SQ
NT seq
1809 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgggcgcgtagccaccggcgcgcgggtctcttcctggccgcggttttcccgcgc
ggggtaacgaccagggtcacgggacggcgggagctgagcgcgcggcccgcgccgcaggag
cccggcatggaataccaggacgctgtgcgcacactcaacagcctgcagaccaatgccagc
tacctggcggaggtgaagcgccggcggggtgacctccagacacagctggaaaccatgaag
ctgtacttggcacggagtgggctgcaggtggaggacttggaccagctgaacatcatccac
gttactgggacaaaggggaagggctccacctgtgccttcactgaacggatcctccggaac
tatggcctgaagacaggattctttaggtctcccggcagctctccccacctggtgcaggtg
cgcgagcggatccgcatcaatgggcagcccatcagccccgagcacttcaccaagcacttc
tggcgcctctaccatcggctggaggagaccaaggacagcagcagctgtgtctccatgcct
gcatacttccgcttcctcacgctcatggccttccatgtcttcctgcaagagaaggtggac
ctggcagtggtggaagtgggtatcggtggtgcttatgactgcaccaacataatcaggaag
cctgtggtatgtggggtctcctctcttggcatcgaccacactagccttctgggggacacg
atggagaagatcgcatggcagaaagggggcatcttcaaggtgattggacagccgcaggga
ggggagcatggcgtccctgccttcaccgtgccccagcctgatgggcccctggcagtgctg
agggagcgtgctgagcagatctcatgtcccctctacctgtgtccaccgctggaagccctg
gaggaaggggagccaccgttgaccctgggcctggagggagagcaccagcgggccaatgcc
gcgttggccttgcagctggcccgctgctggctgcagcgaaaggaccaccaaggcattggg
gagctgaaagcctccaggccaagcctgctgtgtcagctgcctctggcacccgtgttccag
cccacatcccacatgcggcatgggcttcgggacacggagtggccaggccggacgcagaca
ctgcgccgcgggcccctcacctggtacctggatggcgcgcacacctccagcagcgtgcag
gcctgcgtgcgctggttccgccaggcgctgcaccgccgccccaagagtgggcctgaggtg
cctgaggtgcgcgtcctgctcttcaactccacgggtgaccgcgacccggcgcccctgctg
aagctgttgcggccctgccagtttgactatgctgtcttctgccctaacctgacggaggtg
tcatccacggacaacgcagaccagcagaacttcatggtgaccctggaccaggtgctgctc
cgctgcttggagcaccagcagcactggagccgcctggatgaggaggcagccagcccggac
ctctggagcacccccggcccggaggctggtgggccggcgtccctgctgctggcaccccgc
ctgccccacgcccacggcaccagctccctcgtcttcagctgcatctcccatgctttgcag
tggatcagccagggccgggaccccgacttgcagacacccagttccccacgggaccttctc
gcccaccctgtggccagcagcggggccagcgtgctccgagaggctgctgccgtccacgtg
ctggtcacaggaagcctgcacctggtgggcggcgtcctgaagctgctggatccctccctg
tcccagtag
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