Myotis myotis (greater mouse-eared bat): 118669941
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Entry
118669941 CDS
T07220
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
mmyo
Myotis myotis (greater mouse-eared bat)
Pathway
mmyo00562
Inositol phosphate metabolism
mmyo01100
Metabolic pathways
mmyo04014
Ras signaling pathway
mmyo04015
Rap1 signaling pathway
mmyo04020
Calcium signaling pathway
mmyo04024
cAMP signaling pathway
mmyo04070
Phosphatidylinositol signaling system
mmyo04919
Thyroid hormone signaling pathway
mmyo04933
AGE-RAGE signaling pathway in diabetic complications
mmyo05205
Proteoglycans in cancer
Module
mmyo_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
mmyo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
118669941 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
118669941 (PLCE1)
04015 Rap1 signaling pathway
118669941 (PLCE1)
04020 Calcium signaling pathway
118669941 (PLCE1)
04070 Phosphatidylinositol signaling system
118669941 (PLCE1)
04024 cAMP signaling pathway
118669941 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
118669941 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
118669941 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
118669941 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mmyo04131
]
118669941 (PLCE1)
Enzymes [BR:
mmyo01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
118669941 (PLCE1)
Membrane trafficking [BR:
mmyo04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
118669941 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
118669941 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
118669941
NCBI-ProteinID:
XP_036192443
LinkDB
All DBs
Position
Unknown
AA seq
2302 aa
AA seq
DB search
MTSEEMAASDLIPVTQRKVVSSQSAADESSEKASGVSVPKTHTPGQSRPTSHTISKLNKP
KEETSGSNLPRIFSTTRGKIMSDENSNETCWEKNMPDSVKNLNVNGNNILENRQCGLPQS
QFYKTCDSVVEEGLHLETGISSSLERKVFPGIQLELDGPPMGIRPLENQSATSRAHPDSD
LAVFHFHYELDRRMSDSVCTLSDNLILDDCGNCVSLPDVGREQKKNYMAYTCKLMELAKS
CDNENKQLQGDHCDALNDEYMCCEASCRKASVVCSSDSFCREGFTDSPSAETFLSHFEDF
PDNCEDVEDYFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLAAWSYI
DMKRSGSLLPCGRVTGQLSTVLVRQDGSPCLSEAQWYPIYNAVRRGEETEDTIGSLLHFF
TKLPASETAYERINVGPCLKQCVRDTVCEYRATLQRTSISQYITGSLLEATTSLGARSGL
LSTFGGSTGRMMLKERQPGTSMANSNALPSSSAGISKELIDLQPLIQFPEEVASILMEQE
QNIYRRVLPVDYLCFLTQNLSTPECQRSLPCLKASISASILNSQNREHNALEDLVMRFNE
VSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNTVMEFLAGLRSRKVLKMWQFM
DQSDLETMRSLKDAMAQHESSCEYRKVVTRALHIPGCRVVPFCGVFLKELCEVLDGASGL
VKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQIIRSCSRSLEA
EDEDSPSEGSGSRKNSLKDKAPRCQFVIGDLLDTENDIFEQPKEWDPHGLEEPQKAFDHG
IELIPWYVLSIRADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWIKPTTASPA
SAKAKLGMPTATSEPGKFPLLGNAGLSGLAEGVLDLFSVKAVYMGHPSIDIHTVCVQNKL
SSMFLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTKAVRKMRKFPDQRQQW
LRKQYVSLYQHTVILQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKSAEKPNMQRN
NTLGIGTAKKKKKILMRGESGEATDDEMATRKAKLHKECRSWSGSDPQDINEQEESEANA
ITSPPNPLPSRRAHSLTTAGSPILAAGTSSPIRPVSSPVLSSNKSPSSAWSSSSWHGRIK
GGMKGFQSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDLYAVPCNRSGSESAPLYTN
LTIDENTSGLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVEST
SLGVFGVGILQLNDFLVNCQGEHCTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDK
DNFASKNDESQENIKELQLSLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVE
LDCWDGDDGMPIIYHGHTLTTKIPFKDVIEAIDRSAFINSDLPIIISIENHCSLPQQRKM
ADIFKTVFGEKLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAH
QLASMQAQAYNGGNVNPPPTNNEEEEDEEDEYDYDYESLSDDNILEDRPESKSCSDKLQF
EYNEEIPKRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKF
PGLSTLNASGSNRGKERKSRKSIFGNNPGRMSPGETASLNKTSGKSSYEGMRQAWEESSS
PLSPATSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSS
NPNPLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFS
PLERDLDNMEPAVYSLTIVSGQNVCPSNSTGSPCIEVDILGMPLDSCHFRTKPIHRNTLN
PMWNEQFFFRVHFEDLIFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLE
ISSLFVNSRRMEEVSSGSSMPASLMFSTEERKCLQTHRVTVHGVPGPEPFTVFSINGGTK
AKQLLQQILTTEQDTKPIATDYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIVQILSSW
FPEEGYVGRIVLKTQQENLEEKSIVQDDREVILSSEEESFFVQVHDVSPEQPRTVIKAPR
VSTAQDVIQQTLCKAKYSYSILSNPNPNDYVLLEEVVKDTANKKSSTPKSSQRVLLDQEC
VFQAQSKWKGAGKFILKLKEQVQASREDKRKGISFASEFKKFTKSTKQPRGLTSPSQVLV
SESVQNKEERPVGGSDTMDYRQ
NT seq
6909 nt
NT seq
+upstream
nt +downstream
nt
atgacttctgaagaaatggcagcttctgatctcatacctgtgactcagagaaaagtggtg
tcttctcagtcagcagcagatgaaagtagtgaaaaggcctcaggcgtcagtgttccaaag
acacatactcctgggcagagtaggccgacttctcataccatctcaaaactgaacaaaccc
aaagaggaaacttctggaagcaacttgcctaggattttctcaacaacaagggggaaaatc
atgagtgatgagaacagtaatgaaacgtgctgggagaaaaacatgcccgattctgtgaag
aaccttaacgtgaacggcaacaacatattggaaaaccgtcagtgtggtcttcctcagagc
cagttttacaaaacatgcgattctgttgtagaagaaggcctgcatttggaaactggaatc
tcttcttccctggaaagaaaggtgttccctgggattcaactggaactagacggacctccc
atgggcattcgtcccttagaaaatcaatcagcaaccagcagggcacaccctgacagcgat
ttggcggtatttcactttcattatgaacttgacagaagaatgtcagacagtgtctgtacc
ctatcagacaacttgattttggatgattgtggaaactgtgtatcactgcctgatgttggt
agggagcaaaagaaaaattatatggcatatacttgcaaactgatggaattggcaaaaagc
tgtgataatgagaacaagcagctacagggtgatcattgtgacgccttgaacgatgaatac
atgtgctgcgaagcttcctgccgaaaggccagcgtggtatgttctagtgacagcttctgc
agggagggttttactgatagtccatctgccgagacttttctgagccattttgaggacttc
cctgataattgtgaagacgtagaagattattttaaaagtaaaaaggagcgatccactttg
ttagtgaggagattttgtaaaaatgacagagaagttaagaaatctgtgtatactgggaca
agggcaattgtgaggactctgccttctggtcacattggactggcagcttggagttacatt
gatatgaagagaagtggaagcttgttgccttgtgggagagtaacgggccagctatcaaca
gtgctggttaggcaagatgggagcccctgtctgtcagaagcccagtggtatccgatctac
aatgcagtgagaaggggagaagaaacagaagatacaattggatctcttctccatttcttc
acaaagctcccagcctctgagacagcctatgaaaggattaatgttggtccctgcttaaag
caatgtgttcgagacaccgtatgtgagtatcgtgccaccctccaacggacctccatatct
cagtacatcacgggttctctcctagaagcaaccacatctttaggagcaagaagtgggctt
ctcagtacttttggaggatccaccggacgaatgatgctgaaagaacgccaaccgggcacc
tctatggccaattccaatgccctcccttcaagttcagctgggatcagcaaggagctgatt
gatctgcagcccctcatccagttccccgaggaagtcgccagcatcctgatggagcaggaa
cagaatatctaccgaagggtcttgccggttgactatctttgcttcttgacccagaacttg
agcactccagaatgtcagaggtccctgccctgcctcaaagcatccatctcagcatcaatt
cttaactcccagaacagagagcacaatgctcttgaagatctcgtgatgagatttaatgag
gtgagctcctgggtgacgtggctgatcctcacagccggctccatggaggagaagcgggaa
gtcttctcatatttggtgcatgtggccaaatgctgctggaacatgggcaactacaacacc
gtcatggagttcttggccggcctcaggtcaagaaaagttttaaaaatgtggcagttcatg
gaccagtctgacctggagaccatgaggagtctgaaggatgccatggctcagcacgaatcc
tcctgcgagtacaggaaggtggtgacgcgggcgctgcacatcccgggctgcagggtggtc
ccgttctgcggggtgtttctgaaggagctctgtgaagtgctggatggcgcctccggcctc
gtgaagctctgccccagatacaattcccaggaggaaactctagagtttgtagctgactac
agtggacaagataattttttacaacgtgtgggacaaaatggtttgaagaattcggaaaaa
gagtccaccgtcaacagcatctttcagatcatcaggagctgcagccgcagtctggaggcg
gaggacgaggacagccccagtgaggggagcggctctcggaaaaactccctgaaggacaaa
gctcctcgctgccagtttgtaattggagatttgctggacacagaaaatgacatctttgaa
cagcccaaagagtgggaccctcatgggttagaagagccacagaaggcctttgaccacggg
atagagctcatcccatggtacgtgctgtccatccgagctgacgtgcaccagttcctgctg
cagggggccacggtcatccactatgaccaggacacgcacctctctgcccgctgcttcctc
cagcttcagcctgacaatagcaccttgacctggataaagcccaccacagcctccccagct
agtgcaaaagcaaaacttggtatgcctactgccacgtccgagcctggcaaattcccatta
ctgggcaatgctggattaagtggcctggcggagggggtcttggatttgttttccgtaaag
gctgtgtacatggggcaccctagcattgatatacacactgtgtgtgttcagaacaaactg
agtagcatgtttctctcggagactggtgtgacactgctctatgggcttcagaccacggac
aatagattactgcactttgtggcaccaaagcacacagctaaaatgctcttcagtgggttg
ttggaactcactaaagctgtgagaaagatgaggaagttccctgaccaaagacagcagtgg
ctgcggaaacagtacgtcagcctctatcagcatacggttattctacaggaggatggacgg
tatgaaggcccaactttggctcacgctgtggagctgtttggtggcagacgatggagtact
cgaaaccccagccctgggacatcagcaaagagtgccgagaagcccaacatgcagaggaac
aacaccctgggcatcggtactgccaagaagaagaagaaaatccttatgaggggtgagagt
ggagaggccaccgacgacgagatggccacccgaaaggccaaactgcacaaagagtgtcga
agctggagtggctctgatcctcaggacattaacgagcaagaggagtcagaggcgaatgcc
atcacaagcccgcctaaccctctcccttccagaagagcccattctctgactacggctggg
tcccccatcttggctgccgggacgtcatctcccatcaggccagtgtcctcccctgtgctg
tcttcaaacaagagcccgtccagtgcctggagcagcagcagctggcacggccgcatcaaa
ggaggaatgaaaggcttccagagcttcatggtttccgacagcaacatgagtttcgttgaa
tttgtggagctgttcaaatccttcagtgtaaggagccgcaaggacctgaaggatctcttc
gacctctacgccgtgccctgcaaccggtcgggctccgagtcggccccgctctacaccaac
ctaaccattgacgagaacaccagcggtcttcagcctgatctagatttgttgaccagaaat
gtctcagatttggggctgttcattaagagtaaacagcagctgtcagacaaccagaggcag
atctctgacgccattgctgctgcaagcatcgtgacgaatggcactggggtcgagagcaca
tccctgggcgtgtttggggtcggcatacttcagctcaatgacttcctagtgaactgccag
ggagaacactgcacttacgatgaaatcctcagcatcatccagaagtttgagcctagcatt
agtatgtgtcatcagggcctaatgtcatttgaaggatttgcaaggtttctgatggataaa
gacaactttgcttcaaaaaacgatgaatcacaggagaacattaaagaattacagctgtcc
ctctcttactattacattgaatcttcacacaatacctacctcacaggccatcagctcaaa
ggagaatcctcagtagaactctacagccaggtcctcctgcaaggctgtaggagcgtagag
ttggactgctgggacggagatgatgggatgcccatcatttaccatggacatacactgaca
accaagatccccttcaaggacgtgattgaagccattgatcgcagtgccttcatcaactct
gacctgccaatcatcatatcaattgagaaccactgttcattgcctcagcaacgaaaaatg
gcagacattttcaagactgtatttggagaaaaactggtggctaagttcttatttgaaagt
gatttctcagatgatccaatgcttccttcccctgaccaacttagaaggaaggtgcttctc
aaaaataagaagctaaaagcccaccagacgccggtggatatcttaaagcaaaaggctcat
cagttagcatccatgcaagctcaggcttacaatggtgggaatgtcaaccccccacctact
aataatgaggaggaggaagatgaagaggacgagtatgattatgactatgaatctctctct
gatgataacattctagaagacagacctgaaagtaaatcgtgtagcgacaagcttcagttt
gagtataatgaagaaatccccaagaggataaagaaagcagataactctgcttgcaacaaa
ggaaaggtgtatgacatggagttgggagaagaattttatcttcctcagaataaaaaggaa
agcagacagattgcaccagagctttctgaccttgtcatctattgccaagcagtaaaattc
ccaggcctgtcaactctaaatgcatctggctctaacagaggaaaagaaaggaaaagcagg
aagtccatttttggcaacaatccgggcagaatgagccctggggagacggcctcacttaac
aaaacatctggaaaaagttcctatgaaggaatgcgacaggcctgggaggagtcttcttcc
cccctcagcccagccacgtccctcagcgctatcattagaactcccaaatgttaccatatc
tcatcgctgaatgaaaatgccgccaaacgtctgtgtcgcaggtattctcagaaactgatc
cagcacaccgcctgccagctgctgaggacttacccggctgccacccgcatcgactcctcc
aaccccaaccccctcatgttctggctgcacgggatacagctcgtggcactcaactaccag
acagatgatctccctttacatttaaacgctgccatgtttgaggccaacggtggctgtggc
tatgtgttgaaacccccagttctgtgggacaagaactgccccatgtatcagaagttttct
cccctggaaagagacctggacaacatggagcccgctgtctactctttgactattgtctct
ggccagaacgtgtgcccgagcaacagcacaggaagcccgtgcatcgaggtcgacatcctg
ggcatgccgctggacagctgccacttccgcacaaagcccatccaccggaacactctgaac
cccatgtggaacgagcagtttttcttccgggtccactttgaagacctcatatttcttcgt
tttgcagttgtggaaaacaacagctcggcggtcactgctcagaggatcatcccgctcaag
gctctaaagcgaggatatcgacatcttcagctgcgaaacctccacaatgaagtcttggaa
atctctagtttattcgtaaacagcagaaggatggaagaagtctcctctggcagttccatg
ccggcctctttgatgtttagtacagaagaaagaaaatgtctgcagactcacagagtcacg
gtgcatggggtcccaggtccggagcccttcactgttttctctataaatggaggcaccaag
gcaaagcaacttctccagcaaattctgaccactgaacaagacaccaaacctattgccaca
gactactttttgatggaagaaaaatattttatatctaaagaaaagaatgaatgcagaaaa
cagccgttccagagggccattggtcccgaggaagagatcgtgcagattttaagcagctgg
tttccagaagagggctatgttggcaggattgtcttaaaaacccagcaggaaaacctggaa
gagaaaagcattgttcaagatgacagggaggtgatcttgagctcggaggaggagagtttc
tttgtccaagtgcacgatgtttctccagagcagccgcggacagtcatcaaagcgccgcgc
gtcagcaccgcacaggacgtcattcagcagaccttatgcaaagccaagtactcctacagc
atcctgagcaaccccaacccgaacgactacgtacttttggaagaggtggtgaaagacaca
gccaacaagaagtcttctacccccaagtcctcccagcgggtccttttggatcaggagtgt
gtgtttcaagcccaaagcaagtggaaaggagcaggaaaattcatccttaagctaaaggag
caggtgcaggcatcccgagaagacaagagaaaaggcatttcttttgcaagtgaattcaag
aagttcaccaagtcaactaaacagccccgaggactcacatcaccttctcaggtcttggtt
tcggaaagtgtccaaaacaaagaggagagacctgtgggtggcagcgacacgatggactat
cgacagtga
DBGET
integrated database retrieval system
