Myotis myotis (greater mouse-eared bat): 118671218
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Entry
118671218 CDS
T07220
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
mmyo
Myotis myotis (greater mouse-eared bat)
Pathway
mmyo01521
EGFR tyrosine kinase inhibitor resistance
mmyo01522
Endocrine resistance
mmyo01524
Platinum drug resistance
mmyo04010
MAPK signaling pathway
mmyo04012
ErbB signaling pathway
mmyo04020
Calcium signaling pathway
mmyo04066
HIF-1 signaling pathway
mmyo04151
PI3K-Akt signaling pathway
mmyo04510
Focal adhesion
mmyo04520
Adherens junction
mmyo04530
Tight junction
mmyo05200
Pathways in cancer
mmyo05205
Proteoglycans in cancer
mmyo05206
MicroRNAs in cancer
mmyo05212
Pancreatic cancer
mmyo05213
Endometrial cancer
mmyo05215
Prostate cancer
mmyo05219
Bladder cancer
mmyo05223
Non-small cell lung cancer
mmyo05224
Breast cancer
mmyo05226
Gastric cancer
mmyo05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mmyo00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
118671218 (ERBB2)
04012 ErbB signaling pathway
118671218 (ERBB2)
04066 HIF-1 signaling pathway
118671218 (ERBB2)
04020 Calcium signaling pathway
118671218 (ERBB2)
04151 PI3K-Akt signaling pathway
118671218 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
118671218 (ERBB2)
04520 Adherens junction
118671218 (ERBB2)
04530 Tight junction
118671218 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
118671218 (ERBB2)
05206 MicroRNAs in cancer
118671218 (ERBB2)
05205 Proteoglycans in cancer
118671218 (ERBB2)
05230 Central carbon metabolism in cancer
118671218 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
118671218 (ERBB2)
05226 Gastric cancer
118671218 (ERBB2)
05219 Bladder cancer
118671218 (ERBB2)
05215 Prostate cancer
118671218 (ERBB2)
05213 Endometrial cancer
118671218 (ERBB2)
05224 Breast cancer
118671218 (ERBB2)
05223 Non-small cell lung cancer
118671218 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
118671218 (ERBB2)
01524 Platinum drug resistance
118671218 (ERBB2)
01522 Endocrine resistance
118671218 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmyo01001
]
118671218 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mmyo04147
]
118671218 (ERBB2)
04090 CD molecules [BR:
mmyo04090
]
118671218 (ERBB2)
Enzymes [BR:
mmyo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
118671218 (ERBB2)
Protein kinases [BR:
mmyo01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
118671218 (ERBB2)
Exosome [BR:
mmyo04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
118671218 (ERBB2)
CD molecules [BR:
mmyo04090
]
Proteins
118671218 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
ABC1
Haspin_kinase
Kinase-like
Motif
Other DBs
NCBI-GeneID:
118671218
NCBI-ProteinID:
XP_036194995
LinkDB
All DBs
Position
Unknown
AA seq
1260 aa
AA seq
DB search
MELAAWYRWGLLLALLPPGAAGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNL
ELTHLPGNASLFFLQDIQEVQGYVLIAHSQVTQVPLQRLRIIRGTQLFQDSYALAVLDNG
DQQDSATPVAGASPGGLRELQLRSLTEILKGGVLMQRNPQLCHQDTVLWTDIFHKNNRLA
LLQIDTNRSRACKPCSPSCSPSHCWGESSKDCQILTRTLCASGCARCKGSLPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTTCP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREARAVTSAN
IQEFAGCKKIFGSLAFLPESFEGNPASNTAPLEPEQLRVFETLEEITGYLYISAWPDSLP
ELSVFQNLQVIRGRVLHDGAYSLTLQGLGIRWLGLRSLRELGSGLALIHRNAHLCFVHTV
PWDQLFRNPHQALLHSANRPEDECVGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLQGLPREYVKDRYCLPCHPECQPQNGSVTCLGSEADQCMACAHYKDAPLCVARC
PSGVKTDHSFMPIWKFPDEEGTCQPCPINCTHSCVDLDEKGCPAEQRASPVTSIIAAVVG
ILLVMVVGAVLGVLIRRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEEVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVTEFSRMARDPQRFVVIQNEDLGPTSPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGAGGTAHRRHRSSSTRSGGGELTLGLEPPEEEPPKSPLAPSEG
AGSDVFESDLGMGAAKGLQSLSPHDPSPLQRYSEDPTVPLPPETDGYVAPATCSPQPEYV
NQPEVRPKPPSPLEGPLPPPRSASATLEKPKTLSPKTLSPGKNGVVKDVFAFGGAVENPE
YLAPRGRAAPQPHPPPAFSPAFDNLYYWDQDPSERGSLPSTFEGTPTAENPEYLGLDAPV
NT seq
3783 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtaccgctgggggctcctcctcgccctcctgccccccggagcc
gcgggcacccaagtgtgcaccggcacagacatgaagctgcggctcccagccagtcccgag
acccacctggacatgctccgccacctctaccagggctgtcaggtggtgcagggtaacctg
gagctcacccacctgcctggcaatgccagcctcttcttcctacaggatatccaggaggtg
cagggctacgtgctcatcgctcacagccaagtgacacaggtcccgctgcagaggctgcga
atcatccgaggcacccagctctttcaggacagctatgccctggccgtgctggacaacgga
gaccagcaggacagcgccacccctgtcgccggggcctccccaggagggctgcgggagctg
cagcttcgaagcctcacagagatcctgaagggaggggtgttgatgcagcggaacccacag
ctctgccaccaggacaccgtcctgtggacggacatcttccacaagaacaaccggctggcc
ctcctgcagatagacaccaaccgctcgcgggcctgcaaaccctgttctccatcctgcagc
ccttcccactgctggggagagagttccaaggactgtcagatcttgactcgaactctgtgt
gccagcggctgtgctcgctgcaaaggctcactgcccaccgactgctgccacgagcagtgt
gctgccggctgcacgggccccaagcactctgactgcctggcctgcctccacttcaaccac
agtggcatctgtgagttgcactgcccagccctggtcacctacaacacggacacctttgag
tccatgcccaaccccgagggccgctacacctttggtgccagctgtgtgacaacctgtccc
tacaactacctgtcaacggacgtgggatcctgcaccctggtctgtcccctgaacaaccaa
gaggtgacagctgaggacggaacacagcggtgtgagaagtgcagcaagccctgtgcccga
gtgtgctatgggctgggcatggaacacctgcgtgaggcgagggcagtcaccagtgccaat
atccaggagtttgccggctgcaagaagatctttgggagcttggcgtttctgccagagagc
tttgaggggaaccccgcctccaacactgcccccctagagcctgagcagctcagagtgttt
gagaccttggaggagatcacaggttacctgtacatctcggcgtggccagacagcctgcct
gaactcagtgtcttccagaacctgcaagtgatccggggacgcgtgctgcacgacggcgcc
tactcgctgaccctgcaaggactgggcatccgatggctggggctgcgctcgctgcgggaa
ctgggcagtgggctggccctcatccaccgcaacgcccacctctgctttgtccacacggtg
ccctgggaccagctcttccggaaccctcaccaggccctgctccacagtgccaaccggcca
gaggatgagtgtgtgggtgagggcctggcctgctacccgctgtgcgcccacgggcactgc
tggggtccggggcccacccagtgtgtcaactgcagccagttccttcggggccaggagtgc
gtggaggagtgccgagtactgcaggggctccccagggagtatgtgaaggacaggtactgt
ctgccttgccaccccgagtgccagccccagaatggctcagtgacctgcttaggatcggag
gccgaccagtgcatggcctgcgcccactacaaggacgcccccctctgcgtggctcggtgc
cccagtggcgtgaagactgaccactccttcatgcccatctggaagttccccgacgaggag
ggcacgtgccagccatgccccatcaactgcacccactcctgcgtggacctggatgagaag
ggctgccccgccgagcagagagccagccctgtgacgtccatcattgctgctgtggtgggc
attctgctggtgatggtcgtgggggcagtcctcggcgtcctgatcaggagaaggcggcag
aagatccggaagtacacgatgcggaggctgctgcaggaaacggagctggtggagccgctg
acgcctagcggggcgatgcccaaccaggctcagatgcggatcctcaaagagaccgagctg
aggaaggtgaaggtgctcggatccggagcttttggcaccgtctacaagggcatctggatc
cccgatggggagaatgtgaagatcccagtggccatcaaagtgttgagggaaaacacatct
cccaaagccaacaaagaaatcttggatgaagcatatgtgatggccggtgtgggctccccg
tatgtgtcgcgcctcctgggcatctgcttgacctccacggtgcagctggtgacacagctc
atgccctatggctgcctcctggaccacgtccgcgaacaccgcgggcgcctgggctcccag
gacctgctgaactggtgtgtgcagattgccaagggaatgagctacttggaggaagtgcgg
cttgtgcacagggacctggctgcccggaatgtactggtcaagagtcccaaccacgtcaag
atcacagactttgggctggctcggctgctggacatcgacgagacggagtaccatgcagat
gggggcaaggtgcccatcaagtggatggcgctggagtccattctccgccgacggttcacc
caccagagtgatgtgtggagctacggtgtgactgtgtgggagctgatgacttttggggcc
aaaccttacgatgggatcccagcccgggagatccctgacctgctggagaagggggaacgg
ctgccccagccgcccatctgcaccatcgatgtctacatgatcatggtcaaatgttggatg
attgactctgaatgccggccccggttccgggagttggtgaccgaattctcccgcatggcc
agggacccccagcgcttcgtggttatccagaacgaggacttgggccccaccagccccttg
gacagcaccttctaccgatcgctgctggaggatgacgacatgggggacctggtggatgcc
gaggagtacctggtaccccagcaaggcttcttctgcccagaccctgccccgggtgcgggg
ggcacggcccaccgcaggcatcgcagctcatccaccaggagtggcggtggcgaactgaca
ctgggcctggagccccctgaggaggagcccccgaaatctccactggcaccctccgagggg
gcgggctctgatgtgtttgagagcgacctgggaatgggggcggccaaggggctgcagagc
ctctccccacatgaccccagccctctacagcggtacagtgaggaccccacagtgcccctg
ccccctgagactgatggctacgttgcccctgcgacctgcagtccccagccagaatacgtg
aaccagccagaggtccgcccgaagcccccctcacccttagagggccccctgccgcctcct
cgatctgccagtgccactctggaaaagcccaagactctctcccccaagactctgtcccct
gggaagaacggggttgtcaaagacgttttcgcctttgggggtgccgtggagaaccctgag
tacctggcaccccgcggcagggctgcccctcagccccaccctcctcccgccttcagtcca
gcctttgacaacctctattactgggaccaggacccatccgagcgtggctctctgcccagc
acctttgaagggacccctacagcagagaaccccgagtatctgggcctggatgcgccagtg
tga
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integrated database retrieval system