KEGG   Myotis myotis (greater mouse-eared bat): 118671218
Entry
118671218         CDS       T07220                                 
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
  KO
K05083  receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
Organism
mmyo  Myotis myotis (greater mouse-eared bat)
Pathway
mmyo01521  EGFR tyrosine kinase inhibitor resistance
mmyo01522  Endocrine resistance
mmyo01524  Platinum drug resistance
mmyo04010  MAPK signaling pathway
mmyo04012  ErbB signaling pathway
mmyo04020  Calcium signaling pathway
mmyo04066  HIF-1 signaling pathway
mmyo04151  PI3K-Akt signaling pathway
mmyo04510  Focal adhesion
mmyo04520  Adherens junction
mmyo04530  Tight junction
mmyo05200  Pathways in cancer
mmyo05205  Proteoglycans in cancer
mmyo05206  MicroRNAs in cancer
mmyo05212  Pancreatic cancer
mmyo05213  Endometrial cancer
mmyo05215  Prostate cancer
mmyo05219  Bladder cancer
mmyo05223  Non-small cell lung cancer
mmyo05224  Breast cancer
mmyo05226  Gastric cancer
mmyo05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:mmyo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118671218 (ERBB2)
   04012 ErbB signaling pathway
    118671218 (ERBB2)
   04066 HIF-1 signaling pathway
    118671218 (ERBB2)
   04020 Calcium signaling pathway
    118671218 (ERBB2)
   04151 PI3K-Akt signaling pathway
    118671218 (ERBB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    118671218 (ERBB2)
   04520 Adherens junction
    118671218 (ERBB2)
   04530 Tight junction
    118671218 (ERBB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118671218 (ERBB2)
   05206 MicroRNAs in cancer
    118671218 (ERBB2)
   05205 Proteoglycans in cancer
    118671218 (ERBB2)
   05230 Central carbon metabolism in cancer
    118671218 (ERBB2)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    118671218 (ERBB2)
   05226 Gastric cancer
    118671218 (ERBB2)
   05219 Bladder cancer
    118671218 (ERBB2)
   05215 Prostate cancer
    118671218 (ERBB2)
   05213 Endometrial cancer
    118671218 (ERBB2)
   05224 Breast cancer
    118671218 (ERBB2)
   05223 Non-small cell lung cancer
    118671218 (ERBB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    118671218 (ERBB2)
   01524 Platinum drug resistance
    118671218 (ERBB2)
   01522 Endocrine resistance
    118671218 (ERBB2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmyo01001]
    118671218 (ERBB2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmyo04147]
    118671218 (ERBB2)
   04090 CD molecules [BR:mmyo04090]
    118671218 (ERBB2)
Enzymes [BR:mmyo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     118671218 (ERBB2)
Protein kinases [BR:mmyo01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   118671218 (ERBB2)
Exosome [BR:mmyo04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   118671218 (ERBB2)
CD molecules [BR:mmyo04090]
 Proteins
  118671218 (ERBB2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 118671218
NCBI-ProteinID: XP_036194995
LinkDB
Position
Unknown
AA seq 1260 aa
MELAAWYRWGLLLALLPPGAAGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNL
ELTHLPGNASLFFLQDIQEVQGYVLIAHSQVTQVPLQRLRIIRGTQLFQDSYALAVLDNG
DQQDSATPVAGASPGGLRELQLRSLTEILKGGVLMQRNPQLCHQDTVLWTDIFHKNNRLA
LLQIDTNRSRACKPCSPSCSPSHCWGESSKDCQILTRTLCASGCARCKGSLPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTTCP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREARAVTSAN
IQEFAGCKKIFGSLAFLPESFEGNPASNTAPLEPEQLRVFETLEEITGYLYISAWPDSLP
ELSVFQNLQVIRGRVLHDGAYSLTLQGLGIRWLGLRSLRELGSGLALIHRNAHLCFVHTV
PWDQLFRNPHQALLHSANRPEDECVGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLQGLPREYVKDRYCLPCHPECQPQNGSVTCLGSEADQCMACAHYKDAPLCVARC
PSGVKTDHSFMPIWKFPDEEGTCQPCPINCTHSCVDLDEKGCPAEQRASPVTSIIAAVVG
ILLVMVVGAVLGVLIRRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEEVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVTEFSRMARDPQRFVVIQNEDLGPTSPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGAGGTAHRRHRSSSTRSGGGELTLGLEPPEEEPPKSPLAPSEG
AGSDVFESDLGMGAAKGLQSLSPHDPSPLQRYSEDPTVPLPPETDGYVAPATCSPQPEYV
NQPEVRPKPPSPLEGPLPPPRSASATLEKPKTLSPKTLSPGKNGVVKDVFAFGGAVENPE
YLAPRGRAAPQPHPPPAFSPAFDNLYYWDQDPSERGSLPSTFEGTPTAENPEYLGLDAPV
NT seq 3783 nt   +upstreamnt  +downstreamnt
atggagctggcggcctggtaccgctgggggctcctcctcgccctcctgccccccggagcc
gcgggcacccaagtgtgcaccggcacagacatgaagctgcggctcccagccagtcccgag
acccacctggacatgctccgccacctctaccagggctgtcaggtggtgcagggtaacctg
gagctcacccacctgcctggcaatgccagcctcttcttcctacaggatatccaggaggtg
cagggctacgtgctcatcgctcacagccaagtgacacaggtcccgctgcagaggctgcga
atcatccgaggcacccagctctttcaggacagctatgccctggccgtgctggacaacgga
gaccagcaggacagcgccacccctgtcgccggggcctccccaggagggctgcgggagctg
cagcttcgaagcctcacagagatcctgaagggaggggtgttgatgcagcggaacccacag
ctctgccaccaggacaccgtcctgtggacggacatcttccacaagaacaaccggctggcc
ctcctgcagatagacaccaaccgctcgcgggcctgcaaaccctgttctccatcctgcagc
ccttcccactgctggggagagagttccaaggactgtcagatcttgactcgaactctgtgt
gccagcggctgtgctcgctgcaaaggctcactgcccaccgactgctgccacgagcagtgt
gctgccggctgcacgggccccaagcactctgactgcctggcctgcctccacttcaaccac
agtggcatctgtgagttgcactgcccagccctggtcacctacaacacggacacctttgag
tccatgcccaaccccgagggccgctacacctttggtgccagctgtgtgacaacctgtccc
tacaactacctgtcaacggacgtgggatcctgcaccctggtctgtcccctgaacaaccaa
gaggtgacagctgaggacggaacacagcggtgtgagaagtgcagcaagccctgtgcccga
gtgtgctatgggctgggcatggaacacctgcgtgaggcgagggcagtcaccagtgccaat
atccaggagtttgccggctgcaagaagatctttgggagcttggcgtttctgccagagagc
tttgaggggaaccccgcctccaacactgcccccctagagcctgagcagctcagagtgttt
gagaccttggaggagatcacaggttacctgtacatctcggcgtggccagacagcctgcct
gaactcagtgtcttccagaacctgcaagtgatccggggacgcgtgctgcacgacggcgcc
tactcgctgaccctgcaaggactgggcatccgatggctggggctgcgctcgctgcgggaa
ctgggcagtgggctggccctcatccaccgcaacgcccacctctgctttgtccacacggtg
ccctgggaccagctcttccggaaccctcaccaggccctgctccacagtgccaaccggcca
gaggatgagtgtgtgggtgagggcctggcctgctacccgctgtgcgcccacgggcactgc
tggggtccggggcccacccagtgtgtcaactgcagccagttccttcggggccaggagtgc
gtggaggagtgccgagtactgcaggggctccccagggagtatgtgaaggacaggtactgt
ctgccttgccaccccgagtgccagccccagaatggctcagtgacctgcttaggatcggag
gccgaccagtgcatggcctgcgcccactacaaggacgcccccctctgcgtggctcggtgc
cccagtggcgtgaagactgaccactccttcatgcccatctggaagttccccgacgaggag
ggcacgtgccagccatgccccatcaactgcacccactcctgcgtggacctggatgagaag
ggctgccccgccgagcagagagccagccctgtgacgtccatcattgctgctgtggtgggc
attctgctggtgatggtcgtgggggcagtcctcggcgtcctgatcaggagaaggcggcag
aagatccggaagtacacgatgcggaggctgctgcaggaaacggagctggtggagccgctg
acgcctagcggggcgatgcccaaccaggctcagatgcggatcctcaaagagaccgagctg
aggaaggtgaaggtgctcggatccggagcttttggcaccgtctacaagggcatctggatc
cccgatggggagaatgtgaagatcccagtggccatcaaagtgttgagggaaaacacatct
cccaaagccaacaaagaaatcttggatgaagcatatgtgatggccggtgtgggctccccg
tatgtgtcgcgcctcctgggcatctgcttgacctccacggtgcagctggtgacacagctc
atgccctatggctgcctcctggaccacgtccgcgaacaccgcgggcgcctgggctcccag
gacctgctgaactggtgtgtgcagattgccaagggaatgagctacttggaggaagtgcgg
cttgtgcacagggacctggctgcccggaatgtactggtcaagagtcccaaccacgtcaag
atcacagactttgggctggctcggctgctggacatcgacgagacggagtaccatgcagat
gggggcaaggtgcccatcaagtggatggcgctggagtccattctccgccgacggttcacc
caccagagtgatgtgtggagctacggtgtgactgtgtgggagctgatgacttttggggcc
aaaccttacgatgggatcccagcccgggagatccctgacctgctggagaagggggaacgg
ctgccccagccgcccatctgcaccatcgatgtctacatgatcatggtcaaatgttggatg
attgactctgaatgccggccccggttccgggagttggtgaccgaattctcccgcatggcc
agggacccccagcgcttcgtggttatccagaacgaggacttgggccccaccagccccttg
gacagcaccttctaccgatcgctgctggaggatgacgacatgggggacctggtggatgcc
gaggagtacctggtaccccagcaaggcttcttctgcccagaccctgccccgggtgcgggg
ggcacggcccaccgcaggcatcgcagctcatccaccaggagtggcggtggcgaactgaca
ctgggcctggagccccctgaggaggagcccccgaaatctccactggcaccctccgagggg
gcgggctctgatgtgtttgagagcgacctgggaatgggggcggccaaggggctgcagagc
ctctccccacatgaccccagccctctacagcggtacagtgaggaccccacagtgcccctg
ccccctgagactgatggctacgttgcccctgcgacctgcagtccccagccagaatacgtg
aaccagccagaggtccgcccgaagcccccctcacccttagagggccccctgccgcctcct
cgatctgccagtgccactctggaaaagcccaagactctctcccccaagactctgtcccct
gggaagaacggggttgtcaaagacgttttcgcctttgggggtgccgtggagaaccctgag
tacctggcaccccgcggcagggctgcccctcagccccaccctcctcccgccttcagtcca
gcctttgacaacctctattactgggaccaggacccatccgagcgtggctctctgcccagc
acctttgaagggacccctacagcagagaaccccgagtatctgggcctggatgcgccagtg
tga

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