Myotis myotis (greater mouse-eared bat): 118671592
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Entry
118671592 CDS
T07220
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
mmyo
Myotis myotis (greater mouse-eared bat)
Pathway
mmyo04140
Autophagy - animal
mmyo04141
Protein processing in endoplasmic reticulum
mmyo04210
Apoptosis
mmyo04932
Non-alcoholic fatty liver disease
mmyo05010
Alzheimer disease
mmyo05012
Parkinson disease
mmyo05014
Amyotrophic lateral sclerosis
mmyo05016
Huntington disease
mmyo05017
Spinocerebellar ataxia
mmyo05022
Pathways of neurodegeneration - multiple diseases
mmyo05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mmyo00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
118671592 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
118671592 (ERN1)
09143 Cell growth and death
04210 Apoptosis
118671592 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
118671592 (ERN1)
05012 Parkinson disease
118671592 (ERN1)
05014 Amyotrophic lateral sclerosis
118671592 (ERN1)
05016 Huntington disease
118671592 (ERN1)
05017 Spinocerebellar ataxia
118671592 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
118671592 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
118671592 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
118671592 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmyo01001
]
118671592 (ERN1)
Enzymes [BR:
mmyo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
118671592 (ERN1)
Protein kinases [BR:
mmyo01001
]
Serine/threonine kinases: Other
IRE family
118671592 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
Beta-prop_ACSF4
PQQ_2
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
118671592
NCBI-ProteinID:
XP_036195874
LinkDB
All DBs
Position
Unknown
AA seq
1000 aa
AA seq
DB search
MPARRRLLLLLLLALLLPGSRIFGSSSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLK
EDPVLQVPTHVEEPAFLPDPNDGSLYTLGGKHSEGLTKLPFTIPELVQASPCRSSDGILY
MGKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNA
TYFDYAASLPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGL
RKVMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLMPTLYVGKYSTSLYASP
SMVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKLNPGLKGKNKLNYLRN
YWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEDRCNHPLPHKAIHLVD
QTSENAPSTVSQGVEEKFAHAPAKPEAPVDSVLKDIATIVLSTFLLIGWVAFIITYPLSV
HQQQQLQHRQFQKELEKIQLLQQQQLPFHAPGDVAQDAELLDSSGLYSESSGTSSPSTSP
RASNHSLHSSSSASRAGTSPCLEQDDEDEETSMVMVGKISFCPKDVLGHGAEGTIVYRGM
FDSRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQ
EYVEQKDFAHLGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMIS
DFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVVSE
GSHPFGKSLQRQANILLGAYSLDCLQPEKHEDVIARDLIEKMISMDPQKRPSAKHVLKHP
FFWSLEKQLQFFQDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFR
TYKGGSVRDLLRAMRNKKHHYRELPVEVRETLGSLPDDFVRYFTSRFPHLLSHTYRAMEL
CSHERLFQPYYFHPPPEPQAPLTADAPEPGRTPSCGPSCD
NT seq
3003 nt
NT seq
+upstream
nt +downstream
nt
atgcccgcccggcggcggctgctgctgctgctgctgttggcgctgctgctgcccggctcc
aggatttttggaagttccagcacagtgacgcttcctgaaaccttgctgtttgtgtcaacc
ctggatggaagtttgcacgctgtcagcaagaggacaggctcgatcaaatggactttaaaa
gaagatccagttctgcaggttccaacacacgttgaagagcctgccttcctcccggatccc
aacgatggcagtctgtatacacttgggggcaagcacagcgaaggcctaacgaaacttccc
tttaccatcccggagctggtacaggcatcgccatgccgaagttcagatgggattctctac
atgggtaaaaagcaggacatttggtatgtcattgaccttctgaccggggagaaacagcag
actttgtcatcggcctttgcagatagcctctgcccttcaacctctcttctgtaccttggg
cgcacagaatacaccatcaccatgtacgacaccaaaacccgagagctccggtggaacgcc
acctacttcgactacgcagcctcgctgcccgaggacgacgtggactacaagatgtcccat
tttgtgtccaatggcgatgggctggtggtgactgtggacagtgagtctggcgacgtcctg
tggatccagaactatgcctcccctgtggtggccttttacgtctggcagcgggaggggctg
cggaaggtgatgcacatcaacgtcgctgtggagaccctgcgctacctgaccttcatgtcc
ggggaggtggggcgcatcaccaagtggaagtaccccttccccaaggagacggaggccaag
agcaagctgatgcccaccctgtacgttgggaaatactctactagcctctacgcctccccc
tcaatggtccacgagggggttgctgttgtgccccgaggcagcacccttcctttgctggaa
ggcccccagactgacggcgtcaccattggggacaaaggggagtgtgtgatcacacccagc
acggacctgaagcttaaccctgggctcaaagggaagaacaagctcaactacttgaggaac
tactggcttctgatcggacaccatgaaacgccgctgtctgcgtctaccaagatgctggag
agattccccaacaatctgcccaaacaccgggaaaatgtgattcctgccgactctgagaaa
aagagctttgaggacagatgtaaccaccctctcccacacaaggctatccacctggttgac
cagacttcagagaatgcgcccagcaccgtttctcagggtgtggaggagaagttcgctcac
gcccccgccaagcccgaggcccctgtggactccgtgctcaaggacattgccaccatcgtc
ctgagcaccttcctactcatcggctgggtggccttcatcatcacctaccccctgagcgtg
catcagcagcagcagctccagcaccggcagttccagaaggaactggagaaaatccagctc
ctgcagcagcagcagctgcccttccacgcacccggggacgtggctcaggacgccgagctc
ctggactcgtccggcctgtactcggagagctcgggcaccagcagccccagcacgtccccc
cgagcctccaaccactcgctgcactccagcagctctgcctccagggccggcaccagcccc
tgcctggagcaggacgacgaggatgaggaaaccagcatggtgatggttgggaaaatttcc
ttctgtcccaaggacgtcctgggccacggagcggagggcacaattgtgtaccggggcatg
ttcgacagccgcgacgtggcggtcaagaggatcctccccgagtgcttcagcttcgccgac
cgcgaggtccagctgctgcgagagtctgacgagcacccaaacgtgatccgttacttctgc
accgagaaggaccggcagttccagtacatcgccattgagctgtgcgcggccacgctgcag
gagtacgtggagcagaaggactttgcccacctcggcctggagcccatcaccttgctgcag
cagaccacctccggcctggcccacctgcactccctcaacatcgttcacagagacctgaag
ccccacaacatcctcctctccatgcccaatgcgcatggcaggatcaaggccatgatctcc
gacttcggcctctgcaagaagctggcagtgggcaggcacagcttcagccgccgctcgggg
gtgcccggcaccgaaggctggatcgccccggagatgctgagtgaggactgcaaggagaac
cccacctacacggtggacatcttctctgcgggctgcgtgttctactacgtggtttctgag
ggcagccaccctttcggcaagtccctgcagcgacaggccaacatcctcctgggcgcctac
agcctcgactgcttacagcccgagaagcacgaagacgtcatcgcccgggatctgatagag
aagatgatctccatggaccctcagaagcgcccgtcagcgaagcatgtgctgaagcacccg
ttcttctggagcctcgagaagcagctccagttcttccaggacgtgagtgaccggatagaa
aaggagtccctggacggcccgatcgtgaagcagctggagagaggcgggcgagccgtggtg
aagatggactggagggagaacatcaccgtccccctccagacagatctgcgtaaattcaga
acctacaaaggcggctccgtcagagacctcctccgagccatgagaaataagaagcaccac
taccgggagctccccgtggaggtgcgggagaccctgggctccctccccgacgactttgtg
cgctacttcacatcccgcttcccccacctcctctctcacacctaccgggccatggagctg
tgcagccacgagaggctcttccagccctactacttccacccgccccccgagcctcaggcc
cccctgactgcagacgcccctgagccaggccggactccgtcttgtggccccagctgtgac
tga
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