Myotis myotis (greater mouse-eared bat): 118677255
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Entry
118677255 CDS
T07220
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3 isoform X1
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
mmyo
Myotis myotis (greater mouse-eared bat)
Pathway
mmyo00230
Purine metabolism
mmyo00670
One carbon pool by folate
mmyo01100
Metabolic pathways
mmyo01523
Antifolate resistance
Module
mmyo_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mmyo00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
118677255 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
118677255 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
118677255 (GART)
Enzymes [BR:
mmyo01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
118677255 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
118677255 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
118677255 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_4
ATP-grasp_2
CPSase_L_D2
ATP-grasp_3
Dala_Dala_lig_C
RimK
Sacchrp_dh_NADP
Motif
Other DBs
NCBI-GeneID:
118677255
NCBI-ProteinID:
XP_036208115
LinkDB
All DBs
Position
Unknown
AA seq
1009 aa
AA seq
DB search
MAARVLVIGNGGREHTLAWKLAQSRHVKQVLVAPGNAGTADSGKISNTAISVSDHSALAQ
FCKEEDIEFVVVGPEAPLAAGIVGDLAAAGVRCFGPTAQAAQLESSKRFAKEFMDRHGIP
TARWRAFTEPEEARGFILSADFPALVVKASGLAAGKGVIVAESREEACRAVQEIMQDKAF
GAAGETIVIEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDRGPNTGGMGAYCPAP
QVSKDLLLKIKNAILQRTVDGMQQEGTPYTGVLYAGVMLTRDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCAAPPLWLENRAAITVVMASQGYPGDYAKGVEVAGIAEA
QALGLEVFQAGTALKDGKVVTSGGRVLTVTAIRDTLVAALEGAKQGLAAIKFEGAVYRKD
IGSRAIAFLQQPRGLTYKDSGVDIAAGNLLVKKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFKDPLLVSGTDGVGTKLKIAQQCNQHGTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDVGTAAAVVAGIAEACRKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAVERDQQLP
RLESIAEGDVVIGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPHGCGDQTLGDLLLTPTR
IYSQSLLPVLRSGHVKALAHITGGGLLENIPRVLPPRCGVELDARAWRVPPIFSWLQQEG
RLSEEEMARTFNCGVGAALVVSEDLAEPVLRDVRQHQEEAWLIGRVVACPEGSPRVRVRH
LLDALQLSGPVVQNGCTHTPSSAPEKARVAVLISGTGSNLQALIDSTREPSSAAHIVVVV
SNKAAVAGLDRAARAGIPTRVLNHKLYKSRVEFDTAIDQVLAEFSADIVCLAGFMRILSG
PFVRKWNGRMLNVHPSLLPSFKGADAHEQALAAGVAVTGCTVHFVAEDVDAGRIILQEAV
PVRRGDTVATLSERVKVAEHRIFPAALQLVASGAVRLGEDGQLCWAQEE
NT seq
3030 nt
NT seq
+upstream
nt +downstream
nt
atggctgcccgagtgcttgtcattggcaatgggggcagagagcacacgctggcctggaaa
ctggcgcagtctcgtcacgtcaaacaggtgttggtcgcccccgggaatgcaggcactgcc
gactctgggaagatttcaaacactgccatctccgtcagcgatcacagtgcgctcgctcag
ttctgcaaagaggaggacattgaattcgtggttgttggaccagaggcacctctggctgcg
gggatcgtcggggacctggcggcggccggcgtgcggtgctttggccccacagcacaggcg
gctcagctagagtccagcaaaaggtttgccaaagagttcatggaccgacacggcatcccc
accgcccggtggagagccttcaccgagcccgaggaggcccgcggcttcatcctgagtgca
gacttccctgctctggtcgtgaaggccagcggcctggccgccgggaagggggtgatcgtg
gcagagagcagagaagaggcctgcagagccgtgcaggagatcatgcaggataaagctttt
ggagcagctggagaaacgattgtcattgaagaacttcttgaaggagaagaggtttcttgt
ctgtgcttcaccgatgggaggaccgtggctcccatgccccccgcgcaggaccacaagcgg
ctgctggagggagatcgcggccccaacacaggcgggatgggggcctactgcccagccccc
caggtctctaaggatttgctgctgaagattaaaaacgccatccttcagcggacagtggac
ggcatgcagcaggagggcacgccgtacacaggtgttctctatgcgggtgtgatgctcacc
agggatggcccgaaggttctggagtttaactgccgtttcggggacccggagtgccaggtg
atcctcccgctcctgaaaagcgatctctatgaggtgattcagtccaccctggacggcctg
ctctgtgcagctccgcccctttggcttgaaaaccgggcggccatcactgtcgtcatggca
agtcagggctatcccggagactacgccaagggtgtggaggtagcaggcatcgccgaagcc
caggctttagggctggaggtgttccaggcaggcacagccctgaaagacggcaaagtggtg
accagcggagggcgagtcctcacggtgaccgccatccgggacactctcgtcgcagccctc
gaaggggccaagcaaggactggctgccatcaagtttgagggcgccgtctacaggaaggac
attggcagccgcgccatagcgttcctccagcagcccaggggcctgacgtacaaggactct
ggggtagacattgcagctggaaatctgctggtcaagaaaattaagcctttagccaaagcc
acctccagaccaggctgtgatgtggatcttggaggttttgctggtctttttgatttgaaa
gcagcgggtttcaaagaccctctcctggtcagtggaactgatggcgttggcacgaaactg
aagattgcccagcagtgcaaccaacatggtaccattggccaggacttggttgccatgtgt
gtgaacgatatcctggcacaaggggcagagcccctcttcttcctcgactatttttcctgc
gggaaacttgatgttggcacagctgcagcggtcgttgctggcatcgccgaagcgtgcagg
aaagctgggtgtgccctcctcggaggggaaacagcagaaatgccggacatgtatccccct
ggggagtacgacctggctgggttcgccgtgggggccgtggagcgggaccagcaactccct
cgcctggaaagcatcgctgaaggggacgtggttattggaatagcgtcatcgggtctccac
agcaatgggttcagccttgtgaggaagattgtggcgaaatcttcccttcagtactcctcc
ccggcaccccacggctgcggcgaccagaccttgggggacttacttctgactccgaccaga
atctacagccagtccctgttacctgtcttgcgttcgggtcatgtcaaggccttggcccac
atcaccggcggagggctgctggagaacatcccgcgggtcctccccccgaggtgcggggtg
gagttagacgcccgggcctggagggtcccccccatcttctcgtggctgcagcaggaagga
cgcctctcggaggaggagatggccaggacctttaactgcggggtcggggctgccctcgtg
gtgtcggaggacctggcggagccggtgctgagggacgttcggcagcaccaggaggaggcc
tggctgatcggcagggtggtggcctgccccgaaggttctccccgagtgagagtcaggcac
ctgctggatgccctgcagctgagcgggcccgtggtgcagaacggctgcacgcacactccc
tcctctgccccggaaaaggccagagtggccgtcctcatctctgggacaggctcgaacctg
caggcgctgatagacagcacccgggagccgagcagcgccgcacacatcgtcgtggtcgtc
tccaacaaggccgcggtggccgggctggaccgagcggcgcgtgcgggcattcccaccagg
gttcttaatcacaagttatacaaaagccgtgtcgaatttgacacggccattgaccaggtc
ctcgcagagttctccgcggacatcgtctgcctggcagggttcatgaggatcttgtctggc
cccttcgtcaggaagtggaatgggagaatgctcaacgtccacccgtccctgctgccgtcc
ttcaagggcgccgatgcccacgagcaggccctggccgccggcgtcgcggtgacggggtgc
accgtgcactttgtggcggaagacgtggatgccgggcggatcattttacaagaagctgtg
ccggtgaggaggggggacacggtggccaccctgtccgagcgggtgaaggtcgcggagcac
aggatcttccccgcagccctgcagctggtggccagcggtgccgtgcggctgggcgaggac
ggccagctctgctgggcccaggaggagtga
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