KEGG   Myotis myotis (greater mouse-eared bat): 118678909
Entry
118678909         CDS       T07220                                 
Symbol
AKT3
Name
(RefSeq) RAC-gamma serine/threonine-protein kinase isoform X1
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
mmyo  Myotis myotis (greater mouse-eared bat)
Pathway
mmyo01521  EGFR tyrosine kinase inhibitor resistance
mmyo01522  Endocrine resistance
mmyo01524  Platinum drug resistance
mmyo04010  MAPK signaling pathway
mmyo04012  ErbB signaling pathway
mmyo04014  Ras signaling pathway
mmyo04015  Rap1 signaling pathway
mmyo04022  cGMP-PKG signaling pathway
mmyo04024  cAMP signaling pathway
mmyo04062  Chemokine signaling pathway
mmyo04066  HIF-1 signaling pathway
mmyo04068  FoxO signaling pathway
mmyo04071  Sphingolipid signaling pathway
mmyo04072  Phospholipase D signaling pathway
mmyo04140  Autophagy - animal
mmyo04150  mTOR signaling pathway
mmyo04151  PI3K-Akt signaling pathway
mmyo04152  AMPK signaling pathway
mmyo04210  Apoptosis
mmyo04211  Longevity regulating pathway
mmyo04213  Longevity regulating pathway - multiple species
mmyo04218  Cellular senescence
mmyo04261  Adrenergic signaling in cardiomyocytes
mmyo04370  VEGF signaling pathway
mmyo04371  Apelin signaling pathway
mmyo04380  Osteoclast differentiation
mmyo04510  Focal adhesion
mmyo04517  IgSF CAM signaling
mmyo04518  Integrin signaling
mmyo04550  Signaling pathways regulating pluripotency of stem cells
mmyo04611  Platelet activation
mmyo04613  Neutrophil extracellular trap formation
mmyo04620  Toll-like receptor signaling pathway
mmyo04625  C-type lectin receptor signaling pathway
mmyo04630  JAK-STAT signaling pathway
mmyo04660  T cell receptor signaling pathway
mmyo04662  B cell receptor signaling pathway
mmyo04664  Fc epsilon RI signaling pathway
mmyo04666  Fc gamma R-mediated phagosome formation
mmyo04668  TNF signaling pathway
mmyo04722  Neurotrophin signaling pathway
mmyo04725  Cholinergic synapse
mmyo04728  Dopaminergic synapse
mmyo04810  Regulation of actin cytoskeleton
mmyo04910  Insulin signaling pathway
mmyo04914  Progesterone-mediated oocyte maturation
mmyo04915  Estrogen signaling pathway
mmyo04917  Prolactin signaling pathway
mmyo04919  Thyroid hormone signaling pathway
mmyo04920  Adipocytokine signaling pathway
mmyo04922  Glucagon signaling pathway
mmyo04923  Regulation of lipolysis in adipocytes
mmyo04926  Relaxin signaling pathway
mmyo04929  GnRH secretion
mmyo04931  Insulin resistance
mmyo04932  Non-alcoholic fatty liver disease
mmyo04933  AGE-RAGE signaling pathway in diabetic complications
mmyo04935  Growth hormone synthesis, secretion and action
mmyo04936  Alcoholic liver disease
mmyo04973  Carbohydrate digestion and absorption
mmyo05010  Alzheimer disease
mmyo05017  Spinocerebellar ataxia
mmyo05132  Salmonella infection
mmyo05135  Yersinia infection
mmyo05142  Chagas disease
mmyo05145  Toxoplasmosis
mmyo05152  Tuberculosis
mmyo05160  Hepatitis C
mmyo05161  Hepatitis B
mmyo05162  Measles
mmyo05163  Human cytomegalovirus infection
mmyo05164  Influenza A
mmyo05165  Human papillomavirus infection
mmyo05166  Human T-cell leukemia virus 1 infection
mmyo05167  Kaposi sarcoma-associated herpesvirus infection
mmyo05168  Herpes simplex virus 1 infection
mmyo05169  Epstein-Barr virus infection
mmyo05170  Human immunodeficiency virus 1 infection
mmyo05200  Pathways in cancer
mmyo05205  Proteoglycans in cancer
mmyo05207  Chemical carcinogenesis - receptor activation
mmyo05208  Chemical carcinogenesis - reactive oxygen species
mmyo05210  Colorectal cancer
mmyo05211  Renal cell carcinoma
mmyo05212  Pancreatic cancer
mmyo05213  Endometrial cancer
mmyo05214  Glioma
mmyo05215  Prostate cancer
mmyo05218  Melanoma
mmyo05220  Chronic myeloid leukemia
mmyo05221  Acute myeloid leukemia
mmyo05222  Small cell lung cancer
mmyo05223  Non-small cell lung cancer
mmyo05224  Breast cancer
mmyo05225  Hepatocellular carcinoma
mmyo05226  Gastric cancer
mmyo05230  Central carbon metabolism in cancer
mmyo05231  Choline metabolism in cancer
mmyo05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mmyo05415  Diabetic cardiomyopathy
mmyo05417  Lipid and atherosclerosis
mmyo05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmyo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118678909 (AKT3)
   04012 ErbB signaling pathway
    118678909 (AKT3)
   04014 Ras signaling pathway
    118678909 (AKT3)
   04015 Rap1 signaling pathway
    118678909 (AKT3)
   04370 VEGF signaling pathway
    118678909 (AKT3)
   04371 Apelin signaling pathway
    118678909 (AKT3)
   04630 JAK-STAT signaling pathway
    118678909 (AKT3)
   04668 TNF signaling pathway
    118678909 (AKT3)
   04066 HIF-1 signaling pathway
    118678909 (AKT3)
   04068 FoxO signaling pathway
    118678909 (AKT3)
   04072 Phospholipase D signaling pathway
    118678909 (AKT3)
   04071 Sphingolipid signaling pathway
    118678909 (AKT3)
   04024 cAMP signaling pathway
    118678909 (AKT3)
   04022 cGMP-PKG signaling pathway
    118678909 (AKT3)
   04151 PI3K-Akt signaling pathway
    118678909 (AKT3)
   04152 AMPK signaling pathway
    118678909 (AKT3)
   04150 mTOR signaling pathway
    118678909 (AKT3)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    118678909 (AKT3)
   04518 Integrin signaling
    118678909 (AKT3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    118678909 (AKT3)
  09143 Cell growth and death
   04210 Apoptosis
    118678909 (AKT3)
   04218 Cellular senescence
    118678909 (AKT3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    118678909 (AKT3)
   04550 Signaling pathways regulating pluripotency of stem cells
    118678909 (AKT3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    118678909 (AKT3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    118678909 (AKT3)
   04613 Neutrophil extracellular trap formation
    118678909 (AKT3)
   04620 Toll-like receptor signaling pathway
    118678909 (AKT3)
   04625 C-type lectin receptor signaling pathway
    118678909 (AKT3)
   04660 T cell receptor signaling pathway
    118678909 (AKT3)
   04662 B cell receptor signaling pathway
    118678909 (AKT3)
   04664 Fc epsilon RI signaling pathway
    118678909 (AKT3)
   04666 Fc gamma R-mediated phagosome formation
    118678909 (AKT3)
   04062 Chemokine signaling pathway
    118678909 (AKT3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    118678909 (AKT3)
   04922 Glucagon signaling pathway
    118678909 (AKT3)
   04923 Regulation of lipolysis in adipocytes
    118678909 (AKT3)
   04920 Adipocytokine signaling pathway
    118678909 (AKT3)
   04929 GnRH secretion
    118678909 (AKT3)
   04915 Estrogen signaling pathway
    118678909 (AKT3)
   04914 Progesterone-mediated oocyte maturation
    118678909 (AKT3)
   04917 Prolactin signaling pathway
    118678909 (AKT3)
   04926 Relaxin signaling pathway
    118678909 (AKT3)
   04935 Growth hormone synthesis, secretion and action
    118678909 (AKT3)
   04919 Thyroid hormone signaling pathway
    118678909 (AKT3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    118678909 (AKT3)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    118678909 (AKT3)
  09156 Nervous system
   04725 Cholinergic synapse
    118678909 (AKT3)
   04728 Dopaminergic synapse
    118678909 (AKT3)
   04722 Neurotrophin signaling pathway
    118678909 (AKT3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    118678909 (AKT3)
  09149 Aging
   04211 Longevity regulating pathway
    118678909 (AKT3)
   04213 Longevity regulating pathway - multiple species
    118678909 (AKT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118678909 (AKT3)
   05205 Proteoglycans in cancer
    118678909 (AKT3)
   05207 Chemical carcinogenesis - receptor activation
    118678909 (AKT3)
   05208 Chemical carcinogenesis - reactive oxygen species
    118678909 (AKT3)
   05230 Central carbon metabolism in cancer
    118678909 (AKT3)
   05231 Choline metabolism in cancer
    118678909 (AKT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    118678909 (AKT3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    118678909 (AKT3)
   05212 Pancreatic cancer
    118678909 (AKT3)
   05225 Hepatocellular carcinoma
    118678909 (AKT3)
   05226 Gastric cancer
    118678909 (AKT3)
   05214 Glioma
    118678909 (AKT3)
   05221 Acute myeloid leukemia
    118678909 (AKT3)
   05220 Chronic myeloid leukemia
    118678909 (AKT3)
   05218 Melanoma
    118678909 (AKT3)
   05211 Renal cell carcinoma
    118678909 (AKT3)
   05215 Prostate cancer
    118678909 (AKT3)
   05213 Endometrial cancer
    118678909 (AKT3)
   05224 Breast cancer
    118678909 (AKT3)
   05222 Small cell lung cancer
    118678909 (AKT3)
   05223 Non-small cell lung cancer
    118678909 (AKT3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    118678909 (AKT3)
   05170 Human immunodeficiency virus 1 infection
    118678909 (AKT3)
   05161 Hepatitis B
    118678909 (AKT3)
   05160 Hepatitis C
    118678909 (AKT3)
   05164 Influenza A
    118678909 (AKT3)
   05162 Measles
    118678909 (AKT3)
   05168 Herpes simplex virus 1 infection
    118678909 (AKT3)
   05163 Human cytomegalovirus infection
    118678909 (AKT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    118678909 (AKT3)
   05169 Epstein-Barr virus infection
    118678909 (AKT3)
   05165 Human papillomavirus infection
    118678909 (AKT3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    118678909 (AKT3)
   05135 Yersinia infection
    118678909 (AKT3)
   05152 Tuberculosis
    118678909 (AKT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    118678909 (AKT3)
   05142 Chagas disease
    118678909 (AKT3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    118678909 (AKT3)
   05017 Spinocerebellar ataxia
    118678909 (AKT3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    118678909 (AKT3)
   05418 Fluid shear stress and atherosclerosis
    118678909 (AKT3)
   05415 Diabetic cardiomyopathy
    118678909 (AKT3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    118678909 (AKT3)
   04932 Non-alcoholic fatty liver disease
    118678909 (AKT3)
   04931 Insulin resistance
    118678909 (AKT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    118678909 (AKT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    118678909 (AKT3)
   01524 Platinum drug resistance
    118678909 (AKT3)
   01522 Endocrine resistance
    118678909 (AKT3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmyo01001]
    118678909 (AKT3)
Enzymes [BR:mmyo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     118678909 (AKT3)
Protein kinases [BR:mmyo01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   118678909 (AKT3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PH Pkinase_C Kinase-like PH_20 ABC1 PH_11 DUF6932
Other DBs
NCBI-GeneID: 118678909
NCBI-ProteinID: XP_036210987
LinkDB
Position
Unknown
AA seq 477 aa
MSDVTIVKEGWVQKRGEYIKNWRPRYFILKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMSCC
SPTSQIDNIGEEEMDASATHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKIL
KKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSR
ERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITD
TATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELIL
MEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDSKEIMRHSFFSGVNWQDVYDKKLV
PPFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDNESRPHFPQFSYSASGRE
NT seq 1434 nt   +upstreamnt  +downstreamnt
atgagcgatgtgaccattgtgaaagaaggttgggttcagaagaggggagaatatataaaa
aactggaggccacgatatttcattttgaagacagatggctcattcataggatataaagag
aaacctcaagacgtggacctgccttaccccctcaacaacttctcagtggcaaaatgccag
ttaatgaaaacagaacgaccaaagccaaacacattcattatcagatgtctccagtggacc
actgttatagagagaacctttcatgtagatacgccagaggaaagggaagaatggacggaa
gctattcaggctgtagcagacagactccagaggcaagaggaggagaggatgagttgttgc
agtccaacctcacaaattgataatataggggaggaggagatggatgcttctgcaacccat
cataaaagaaagacaatgaatgattttgactatttgaaactactaggtaaaggcactttt
gggaaagttattttggttcgagagaaggcaagtgggaagtattatgctatgaagattctg
aagaaagaagttattattgcaaaggatgaagtggctcacaccctcaccgagagccgggta
ttgaagaacacgaggcatcccttcttgacatccttgaaatattccttccagacaaaagac
cgtttgtgttttgtgatggaatatgtcaatgggggcgagctgtttttccatttgtcgaga
gagcgggtgttctccgaggaccgcacgcgcttctacggcgcggagatcgtctcggccctg
gactacctgcactcggggaagatcgtgtaccgggacctgaagttggagaatttgatgctg
gataaagatggccacataaaaatcacagatttcggactttgcaaagaggggatcacagac
acggccaccatgaagaccttctgtggaaccccggagtacctggcgccagaggtgttggag
gacaacgactacggccgggcggtggactggtggggcctgggggtcgtcatgtatgagatg
atgtgcggcaggctgcctttctacaaccaggaccacgagaagctgttcgaactgatcctg
atggaagacatcaaattccctcgcacgctctcctccgatgcaaaatcactgctttcaggg
ctcttgataaaggatccaaataaacgccttggcgggggaccagatgattcaaaagaaatt
atgagacacagtttcttctctggagtaaactggcaagatgtatatgataaaaagcttgta
ccgccttttaagcctcaagtaacatctgagacagataccagatattttgatgaagaattt
acagctcagactattacaataacaccacctgaaaaatacgacgaggacggcatggacaac
gagagccggccgcacttccctcagttctcctactcggcgagcggccgcgagtag

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