Miniopterus natalensis (Natal long-fingered bat): 107533604
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Entry
107533604 CDS
T05883
Symbol
JAK1
Name
(RefSeq) tyrosine-protein kinase JAK1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
mna
Miniopterus natalensis (Natal long-fingered bat)
Pathway
mna01521
EGFR tyrosine kinase inhibitor resistance
mna04151
PI3K-Akt signaling pathway
mna04217
Necroptosis
mna04380
Osteoclast differentiation
mna04550
Signaling pathways regulating pluripotency of stem cells
mna04620
Toll-like receptor signaling pathway
mna04621
NOD-like receptor signaling pathway
mna04630
JAK-STAT signaling pathway
mna04658
Th1 and Th2 cell differentiation
mna04659
Th17 cell differentiation
mna05140
Leishmaniasis
mna05145
Toxoplasmosis
mna05152
Tuberculosis
mna05160
Hepatitis C
mna05161
Hepatitis B
mna05162
Measles
mna05163
Human cytomegalovirus infection
mna05164
Influenza A
mna05165
Human papillomavirus infection
mna05166
Human T-cell leukemia virus 1 infection
mna05167
Kaposi sarcoma-associated herpesvirus infection
mna05168
Herpes simplex virus 1 infection
mna05169
Epstein-Barr virus infection
mna05171
Coronavirus disease - COVID-19
mna05200
Pathways in cancer
mna05203
Viral carcinogenesis
mna05212
Pancreatic cancer
mna05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
mna00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
107533604 (JAK1)
04151 PI3K-Akt signaling pathway
107533604 (JAK1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
107533604 (JAK1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
107533604 (JAK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
107533604 (JAK1)
04621 NOD-like receptor signaling pathway
107533604 (JAK1)
04658 Th1 and Th2 cell differentiation
107533604 (JAK1)
04659 Th17 cell differentiation
107533604 (JAK1)
09158 Development and regeneration
04380 Osteoclast differentiation
107533604 (JAK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
107533604 (JAK1)
05203 Viral carcinogenesis
107533604 (JAK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
107533604 (JAK1)
09162 Cancer: specific types
05212 Pancreatic cancer
107533604 (JAK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
107533604 (JAK1)
05161 Hepatitis B
107533604 (JAK1)
05160 Hepatitis C
107533604 (JAK1)
05171 Coronavirus disease - COVID-19
107533604 (JAK1)
05164 Influenza A
107533604 (JAK1)
05162 Measles
107533604 (JAK1)
05168 Herpes simplex virus 1 infection
107533604 (JAK1)
05163 Human cytomegalovirus infection
107533604 (JAK1)
05167 Kaposi sarcoma-associated herpesvirus infection
107533604 (JAK1)
05169 Epstein-Barr virus infection
107533604 (JAK1)
05165 Human papillomavirus infection
107533604 (JAK1)
09171 Infectious disease: bacterial
05152 Tuberculosis
107533604 (JAK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
107533604 (JAK1)
05140 Leishmaniasis
107533604 (JAK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
107533604 (JAK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mna01001
]
107533604 (JAK1)
Enzymes [BR:
mna01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
107533604 (JAK1)
Protein kinases [BR:
mna01001
]
Non-receptor tyrosine kinases
JAK family [OT]
107533604 (JAK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
ABC1
SH2
RIO1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
107533604
NCBI-ProteinID:
XP_016063856
LinkDB
All DBs
Position
Unknown
AA seq
1153 aa
AA seq
DB search
MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVLFYLTDREPLRLGSGEYTAEEL
CIRAAQECSISPLCHNLFALYDESTKLWYAPNRTITVDDKTSLRLHYRMRFYFTNWHGTN
DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
DGHDIENECLGMAVLAISHYAMIKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEIN
RFNTNDSGNILYYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKHKKEEEKSKAR
EEWSSFSYFPEITHIVIKDAAVSINKQDNRKMELKLSSHEEALSFVSLVDGYFRLTADAH
HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
CFEKPEVLGGQKQFKNFQIEVQKGRYSLHGSDRGFPSLEELMSHLKKQILRTDNISFVLK
RCCQPKPREISNLLVATKKAQEWQPVFPMSQLSFDRILKKDITQGEHLGRGTRTHIYSGT
LMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV
ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL
LAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT
TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI
MRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT
GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS
GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD
FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD
SSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTT
FQNLIEGFEALLK
NT seq
3462 nt
NT seq
+upstream
nt +downstream
nt
atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgagg
agctccaagaagaccgaggtgaatctggaggcccctgagccaggggtagaagtgctcttc
tatctgacggacagggagcccctccggctgggcagcggagaatacaccgcggaggagctg
tgcatcagggcagcgcaggagtgctctatctctcctttgtgccacaacctctttgcccta
tatgatgagagcaccaagctttggtatgctccgaatcgcaccatcacagttgacgacaag
acttcgcttcggcttcactaccggatgaggttctattttaccaactggcatgggaccaat
gataatgagcagtcagtgtggcgacattctccaaagaagcagaaaaatggctacgagaaa
aaaaaagttccagatgcaactcctcttcttgacgccagctccctggagtatctgtttgct
cagggacagtatgatttggtcaaatgcctggctcccattcgagaccccaagacggagcag
gatgggcacgacatcgagaacgagtgtctggggatggccgtcctggccatctcccactat
gccatgataaagaaaatgcagttgccagaactccccaaggacatcagctacaagcgatat
attccagaaacattgaataaatccatcagacagaggaaccttcttaccaggatgcggata
aataatgtcttcaaggatttcctaaaggaatttaacaacaagaccatttgtgacagcagt
gtgtccactcatgacctgaaggtgaaatacctggctaccttggaaactttgacaaaacat
tatggtgctgaaatatttgagacttccatgttactgatttcatcagaaaatgagatcaat
cggtttaatacgaatgacagtggaaacattctctactatgaagtgatggtgactggaaat
cttggaattcagtggaggcagaaaccaaatgttgttcctgttgaaaaggaaaaaaataaa
ttgaaacggaaaaaacttgaaaataaacacaagaaggaggaggagaagagcaaggcccgc
gaggagtggagcagcttttcctacttccccgagatcacccacattgtgatcaaggacgcg
gccgtcagcattaataagcaggacaacaggaaaatggaactgaagctctcttctcacgag
gaggccttgtcatttgtgtccctggtagacggctactttcggctcacagcagatgcccat
cattacctctgcaccgatgtggctcccccattgatcgtccacaacatacagaatggctgt
cacggtccaatttgcacagaatacgccatcaataaattgcggcaagaaggaagcgaggag
gggatgtatgtgctgcggtggagctgcactgactttgacaacatcctcatgaccgtcacc
tgctttgaaaagcctgaggtgctgggtggccagaaacagttcaagaactttcagatcgag
gtgcagaagggtcgctacagtctgcacggctccgaccgcggcttccccagcctggaggag
ctcatgagccacctcaagaagcagatcctgcgcacagacaacatcagcttcgtgctgaag
cgctgctgccagcccaagccccgagaaatctccaatctgctggtggctaccaagaaagcc
caggagtggcagcccgtcttccccatgagtcagctgagtttcgatcggatcctcaagaaa
gacatcacgcaaggcgagcaccttgggagaggcacacggacacacatctactctgggacc
ctcatggattacaaagatgacgaaggaacttctgaagagaagaaaataaaagtgatcctc
aaagtcctggaccccagccacagggacatttctctggccttcttcgaggcagccagcatg
atgaggcaggtctcccacaagcacatcgtgtacctctatggtgtctgtgtccgagacgtg
gagaatatcatggtggaagagtttgtggagggagggcccctggatctcttcatgcaccgg
aaaagcgacgtcctcaccacaccgtggaaattcaaagttgctaaacagctggccagtgcc
ctgagctacttggaagataaagacctggtccatggaaacgtgtgcactaaaaacctcctc
ctggcccgcgagggcatcgacagtgagtgtggcccattcatcaagctcagtgaccccggc
atccccatcactgtgctgtccaggcaagagtgcatagaacgaatcccgtggattgctccc
gagtgtgttgaagactccaagaacctgagcgtggctgctgacaaatggagctttggaacc
acactctgggaaatctgctacaatggcgagatccccctgaaagacaagacactgattgag
aaagagagattctacgaaagccggtgcagaccagtgacaccgtcttgtaaggagctggct
gaccttatgactcgctgcatgaactatgaccccaatcagagaccctttttccgagccatc
atgagagatatcaataagctggaagagcagaatccagacattgtttcagaaaaaaagcct
gcaaccgaagtggatcccacacattttgaaaagcggttcttaaaaaggatccgtgacttg
ggagagggccactttgggaaggttgagctctgcaggtatgaccctgaaggggacaataca
ggggagcaggtggctgtcaaatccctgaagcctgagagtggaggtaaccacatagctgat
ctgaagaaggaaattgaaatcttaaggaacctgtatcatgagaacattgtcaagtacaaa
ggcatctgcacagaagacggaggaaatggaattaagctcatcatggaatttctcccttcg
ggaagccttaaggaatatcttccaaagaataagaacaaaattaacctcaaacagcagtta
aaatatgctgttcagatttgtaaggggatggactatttgggttcacgacagtacgttcac
cgggacttagcagcaaggaatgtccttgttgagagtgagcaccaagtgaaaattggagac
ttcggcttaaccaaagcaattgaaaccgataaggagtactacacagtcaaagacgatcgc
gacagccctgtgttctggtatgctccggaatgtttaattcagtgtaaattttatatcgcc
tctgacgtctggtcttttggagtgactctgcatgagctgcttacttactgtgattcagat
tccagccccatggccctgttcctgaaaatgataggccccactcacggccagatgacagta
acaagacttgtgaatacgttaaaagaaggaaaacgtttgccttgtccacctaactgtcca
gatgaggtttatcaacttatgagaaaatgctgggaattccaaccatctaatcggacaacc
tttcagaaccttattgagggatttgaagcacttttaaaataa
DBGET
integrated database retrieval system
