Mycolicibacterium neoaurum VKM Ac-1815D: D174_17795
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Entry
D174_17795 CDS
T02959
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mne
Mycolicibacterium neoaurum VKM Ac-1815D
Pathway
mne00300
Lysine biosynthesis
mne00550
Peptidoglycan biosynthesis
mne01100
Metabolic pathways
mne01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mne00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
D174_17795
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
D174_17795
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
D174_17795
Enzymes [BR:
mne01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
D174_17795
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AHC26301
UniProt:
V5XF29
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All DBs
Position
complement(3729413..3730912)
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AA seq
499 aa
AA seq
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MIEMTVAQVADIVGGELTDISAADAANTRITGTVEFDSRAVTPGGLFLALPGARSDGHDF
AAGAVAAGAVAVLAARPVGVPAIVVPPAVAGDAGSGAVEHDDAAGSGAAVLAALAKLAAA
VATELSAAGLRIIGVTGSSGKTSTKDLLAAVLAPLGEVVAPPGSFNNELGHPWTVLRATT
DTDFLILEMSARHPGNIAALAAIATPSIGVVLNVGTAHLGEFGSREVIAATKSELPQSVP
ASGVVILNADDSAVSAMADKTAARVVRVSRAPGADIWSADEHLDELARPRFTLHTAGGAV
QVALAVHGEHQVSNALAAAAVAVECGASLEQVATALAGAGPVSARRMNVSTRVDGVTVVN
DAYNANPDSMAAGLKALAWMARSGGPGGRRRSWAVLGEMAELGEDAIAEHDRIGRLAVRL
DVSRLIVVGTGRAMSAMHQGAVMEGSWGSESVLVPDADAALALLAAELSPGDVVLVKASN
AAGLGTLADRLAEQGNEQA
NT seq
1500 nt
NT seq
+upstream
nt +downstream
nt
atgatcgagatgaccgtggctcaggtggccgacatcgtcggcggcgaactgaccgatatc
agcgccgcggacgccgcgaacacccgcatcaccggaaccgtcgagttcgattcgcgcgcc
gtcacgccgggcgggttgttcctggcgctgccgggggcacgttcggacgggcatgatttc
gccgcgggcgccgtcgcggccggagcggtggcggtgctggccgcccgcccggtcggggtg
cctgccatcgtcgtaccgcccgcggtggccggcgacgccggttccggtgcggtggagcat
gacgatgccgcgggctcgggtgccgcggtgctggccgcgctggccaagctggccgcggcc
gtcgcgaccgagctgagcgcggccggtctgcgcatcatcggcgtcaccggttcgtcgggc
aagacctcgaccaaggatctgctggcggcggtgctggcaccgctgggtgaggtggtggcc
ccgcccgggtcgttcaacaacgagctcggccatccatggacggtgctgcgcgccaccacc
gacaccgacttcctgatcctggagatgtcggcgcgacatccgggcaacatcgccgcactg
gcggccatcgcgaccccgtcgatcggggtcgtgctcaatgtcgggacggcccatctcggt
gagttcggttcacgcgaggtgatcgcggccaccaaatccgaactgccgcaatcggttccc
gcatccggtgtggtgatcctcaatgccgacgactcggcggtgtcggcgatggccgacaag
accgcggcgcgggtggtgcgggtatcgcgcgcaccgggggccgatatctggtcggccgac
gagcatctcgacgaactggcccgcccgcgtttcaccctgcacaccgcgggcggtgcggtg
caggtcgccctcgcggtgcacggggagcatcaggtgtccaacgcgctggccgccgcggcg
gtcgcggtggagtgcggtgcgagcctggagcaggtggcgacggcactggccggcgccggt
ccggtctcggcgcgccggatgaatgtcagcacccgtgtcgacggggtcaccgtcgtcaac
gatgcctacaacgccaacccggattcgatggcggcggggctgaaggcgctggcctggatg
gcgcgctccggcggaccgggggggaggcgacgcagctgggcggtgctcggtgagatggcc
gagctcggcgaggacgcgattgccgaacacgatcgcatcggccggttggccgtgcgctta
gatgtctctcgattgatagtcgtgggaaccgggagagcgatgagcgccatgcatcagggg
gcggtgatggaagggtcgtggggcagtgaatccgtcctggtgcccgacgccgacgccgcg
ctggcgttgctggcggccgaactgagtcccggtgacgtggtgctggtgaaggcgtccaac
gcggccgggctcggcacgcttgccgatcgtctcgccgagcaggggaacgagcaggcatga
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