Macaca nemestrina (pig-tailed macaque): 105463958
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Entry
105463958 CDS
T08765
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
mni
Macaca nemestrina (pig-tailed macaque)
Pathway
mni00790
Folate biosynthesis
mni01100
Metabolic pathways
mni01240
Biosynthesis of cofactors
mni01523
Antifolate resistance
mni04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
mni00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
105463958 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
105463958 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
105463958 (FPGS)
Enzymes [BR:
mni01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
105463958 (FPGS)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
105463958
NCBI-ProteinID:
XP_011709761
Ensembl:
ENSMNEG00000042960
UniProt:
A0A2K6DWC6
LinkDB
All DBs
Position
Unknown
AA seq
588 aa
AA seq
DB search
MSRARNHLRAALFLAAASARGVTTQVAAQRGLSAWPVPQEPSMEYQDAVRMLNTLQTNAG
YLEQVKRQRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGSTCAFTECILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDGSCVSMPPYFRF
LTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEKIA
WQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPTLEALEEGGPPLALGLDGE
HQRSNAALALQLAHCWLQRQDHHGAGEVKASRPGLLWQLPLAPVFQPTSHMRLGLRNTEW
LGRTQVLRRGPLTWYLDGAHTPSSVQACVRWFRQALQGRERPSGSGPEVRVLLFNATGDR
DPAALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEHQQHWNHLDE
EQASPDLWSAPSPEPAGPTSLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPVFQPPT
PPKGLLTHPVAHSGASVLHEAAAIHVLVTGSLHLVGGVLKLLEPALSQ
NT seq
1767 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgggcgcggaaccacctgcgcgccgctctattcctggcagcggcgtctgcgcgc
ggcgtaacgacccaggtcgcggcgcagcggggcttgagcgcgtggccggtgccgcaggag
cccagcatggagtaccaggatgccgtgcgcatgcttaataccctgcagaccaatgccggc
tacctggagcaggtgaagcgccagcggggtgacccccagacacagctggaagccatggaa
ctgtacctggcacggagtgggctgcaggtggaggacttggaccggctgaacatcatccac
gtcactgggacgaaggggaagggctccacttgtgccttcacggaatgtatcctccgaagc
tatggcctgaaaacgggattctttagctctccccacctggtgcaggttcgggagcggatc
cgcatcaatgggcagcccatcagtcccgagctcttcaccaagtacttctggcgcctctac
caccggctggaggagaccaaggatggcagctgtgtttccatgcccccctacttccgcttc
ctgacactcatggccttccacgtcttcctccaagagaaggtggacctggcagtggtggag
gtgggcattggcggggcttatgactgcaccaacatcatcaggaagcctgtggtgtgcggc
gtctcttctcttggcatcgaccacaccagcctcctgggggacacggtggagaagattgca
tggcagaaagggggcatctttaagcaaggcgtccctgccttcactgtgctccaacctgaa
ggtcccctggcagtgctgagggaccgagcccagcagatctcatgtcctctctacctgtgt
ccgacgctggaggccctggaggaaggggggccgccgctggccctgggcctggacggggag
caccagcggtccaatgccgccttggccttgcaactggcccactgctggctgcagcggcag
gaccaccatggtgctggggaggtgaaagcatccaggccggggctcctgtggcagctgccc
ctggcacccgtgttccagcccacatcccacatgcggctcgggcttcggaacacggagtgg
ctggggcggacacaggtgctgcggcgcgggccccttacctggtacctggacggcgcgcac
acccccagcagcgtgcaggcctgcgtgcgctggttccgccaggcgctgcagggccgagag
aggccgagcggcagtgggcccgaggttcgagtcttgctcttcaatgctaccggggaccgg
gacccagcggccttgctgaaactgctgcagccgtgccagtttgactatgccgtcttctgc
cccaacctgacagaggtgtcatccacaggcaatgcagaccaacagaacttcacggtgaca
ctggaccaggttctgctccgctgcctggaacaccagcagcactggaaccacctggacgaa
gagcaggccagcccagacctctggagcgcccccagcccagagcctgctgggcccacatcc
ctactgctggcgccccacccaccccacacctgcagcgccagctccctcgtcttcagctgt
atttcacatgccttgcaatggatcagccaaggccgagaccctgtcttccagccacccact
cccccaaagggcctcctcacccaccctgtggctcacagtggggccagcgtactccatgag
gctgctgccatccatgtgctggtcactggcagcctgcacctggtgggtggtgtcctgaag
ctgctggagcctgcactgtcccagtag
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