KEGG   Macaca nemestrina (pig-tailed macaque): 105469063
Entry
105469063         CDS       T08765                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
mni  Macaca nemestrina (pig-tailed macaque)
Pathway
mni04010  MAPK signaling pathway
mni04015  Rap1 signaling pathway
mni04218  Cellular senescence
mni04380  Osteoclast differentiation
mni04620  Toll-like receptor signaling pathway
mni04664  Fc epsilon RI signaling pathway
mni04668  TNF signaling pathway
mni04750  Inflammatory mediator regulation of TRP channels
mni04912  GnRH signaling pathway
mni04935  Growth hormone synthesis, secretion and action
mni04936  Alcoholic liver disease
mni05014  Amyotrophic lateral sclerosis
mni05022  Pathways of neurodegeneration - multiple diseases
mni05132  Salmonella infection
mni05135  Yersinia infection
mni05145  Toxoplasmosis
mni05161  Hepatitis B
mni05163  Human cytomegalovirus infection
mni05167  Kaposi sarcoma-associated herpesvirus infection
mni05169  Epstein-Barr virus infection
mni05170  Human immunodeficiency virus 1 infection
mni05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mni05417  Lipid and atherosclerosis
mni05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mni00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105469063 (MAP2K6)
   04015 Rap1 signaling pathway
    105469063 (MAP2K6)
   04668 TNF signaling pathway
    105469063 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    105469063 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    105469063 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    105469063 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    105469063 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    105469063 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    105469063 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    105469063 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105469063 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    105469063 (MAP2K6)
   05161 Hepatitis B
    105469063 (MAP2K6)
   05163 Human cytomegalovirus infection
    105469063 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105469063 (MAP2K6)
   05169 Epstein-Barr virus infection
    105469063 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105469063 (MAP2K6)
   05135 Yersinia infection
    105469063 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    105469063 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    105469063 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    105469063 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105469063 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    105469063 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    105469063 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mni01001]
    105469063 (MAP2K6)
Enzymes [BR:mni01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     105469063 (MAP2K6)
Protein kinases [BR:mni01001]
 Serine/threonine kinases: STE group
  STE7 family
   105469063 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Haspin_kinase Choline_kinase DUF4344 APH
Other DBs
NCBI-GeneID: 105469063
NCBI-ProteinID: XP_011717939
Ensembl: ENSMNEG00000036682
LinkDB
Position
Unknown
AA seq 278 aa
MELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFY
GALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVI
HRDVKPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSV
KSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLK
KNSKERPTYPELMQHPFFTLHESKGTDVASFVKLILGD
NT seq 837 nt   +upstreamnt  +downstreamnt
atggaactgggacgaggtgcgtacggggtggtggagaagatgcggcacgtgcccagcggg
cagatcatggcagtgaagcggattcgagccacagtaaatagccaggaacagaaaaggcta
ctgatggatttggatatttccatgaggacggtggactgtccattcaccgtcaccttttat
ggcgcactgtttcgggagggtgatgtgtggatctgcatggagctcatggacacatcacta
gataaattctacaaacaagttattgataaaggccagacaattccagaggacatcttaggg
aaaatagcagtttctattgtaaaagcattagaacatttacacagtaagctgtctgtcatt
cacagagacgtcaagccttctaatgtactcattaatgctctcggtcaagtgaagatgtgc
gattttggaatcagtggctacttggtggactctgttgctaaaacaattgatgcgggttgc
aaaccatacatggcccctgaaagaataaacccagagctcaaccagaagggatacagtgtg
aagtctgacatttggagtctgggcatcacgatgattgagttggccatccttcgatttccc
tatgattcctggggaactccatttcagcagctcaaacaggtggtagaggagccatcgcca
caactcccagcagacaagttctctgcagagttcgttgactttacctcacagtgcttaaag
aagaattccaaagaacggcctacatacccagagctaatgcaacatccatttttcacccta
catgaatccaaaggaacagatgtggcatcttttgtaaaactgattcttggagattaa

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