Macaca nemestrina (pig-tailed macaque): 105472217
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Entry
105472217 CDS
T08765
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
mni
Macaca nemestrina (pig-tailed macaque)
Pathway
mni01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
mni00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
105472217 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
mni03032
]
105472217 (TOP2A)
03036 Chromosome and associated proteins [BR:
mni03036
]
105472217 (TOP2A)
Enzymes [BR:
mni01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
105472217 (TOP2A)
DNA replication proteins [BR:
mni03032
]
Eukaryotic type
DNA Topoisomerases
105472217 (TOP2A)
Chromosome and associated proteins [BR:
mni03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
105472217 (TOP2A)
Centrosome formation proteins
Centriole proteins
105472217 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
105472217
NCBI-ProteinID:
XP_011723543
Ensembl:
ENSMNEG00000030734
UniProt:
A0A2K6BNE0
LinkDB
All DBs
Position
Unknown
AA seq
1531 aa
AA seq
DB search
MEVSPLQPVNENMQVNKIKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQ
MWVYDEDVGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFKQTWMDNMGRAGEMELKPFSGEDYTCITFQPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQPKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQ
VQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTDCTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKMLNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKS
STPNYKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD
RKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLKFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNFKGTIE
ELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR
DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENEESDNEKETEKSDSVTDSGPTFNYLLDMPLWYLTKEK
KDELCRLRNEKEQELDTLKRKSPSDLWKEDLATFIEELEAVEAKEKQDEQVGLPGKGGKA
KGKKTQMAEVLPSPCGQRVIPRITIEMKAEAEKKNKKKIKNENTEGSPQEDGMELEGLKQ
RLEKKQKREPGTKTKKQTTLPFKPIKKGKKRNPWSDSESDRSSDESNFDVPPRETEPRRA
ATKTKFTVDLDSDEDFSDFDEKTDDEDFVPSDASPPKTKTSPKLTNKDLKPQKSAMSDLE
ADDAKDSVPLSSSPPATHFPNETEITNTVPKKNVTVKKTAAKSQSSTSTTGAKKRAAPKG
TKKEPALNSGISQKPDPAKTKIRRKRKPSTSDDSDSNFEKIVSKAVTSKKSRGESDDFHM
DFDSAVAPRAKSVRAKKPIKYLEESDEDDLF
NT seq
4596 nt
NT seq
+upstream
nt +downstream
nt
atggaagtgtcaccattgcagcctgtaaatgaaaatatgcaagtcaacaaaataaagaaa
aatgaagatgctaagaaaagactgtctattgaaagaatctatcaaaagaaaacacaattg
gaacatattttgcttcggccagacacctacattggttctgtggaattagtaacccagcaa
atgtgggtttacgatgaagatgttggcattaactatagggaagtcacttttgttcctggt
ttgtacaaaatctttgatgagattctagttaatgctgcggacaacaaacaaagggaccca
aaaatgtcttgtattagagtcacaattgatccggaaaacaatttaattagtatatggaat
aatggaaaaggtattcctgttgttgaacacaaagttgaaaagatgtatgtcccagctctc
atatttggacagctcctaacttctagtaactatgatgatgatgaaaagaaagtgacaggt
ggtcgaaatggctatggagccaaattgtgtaacatattcagtaccaaatttactgtggaa
acagccagtagagaatacaagaaaatgttcaaacagacatggatggataatatggggaga
gctggtgagatggaactcaagcccttcagtggagaagattatacatgtatcacctttcag
cctgatttgtctaagtttaaaatgcaaagcctggacaaagatattgttgcactaatggtc
aggagagcatatgatattgctggatccaccaaagatgtcaaagtctttcttaatggaaat
aaactgccagtaaaaggatttcgtagttatgtggacatgtatttgaaggacaagttggat
gaaactggtaacccattgaaagtaatacatgaacaagtgaaccacaggtgggaagtgtgt
ttaaccatgagtgaaaaaggctttcagcaaattagctttgtcaacagcattgctacttcc
aagggtggcagacatgttgattatgtagctgatcagattgtgactaaacttgttgatgtt
gtgaagaagaagaacaagggtggtgttgcagtaaaagcacatcaggtgaaaaatcacatg
tggatatttgtaaatgccttaattgaaaacccaacctttgactctcagacaaaagaaaac
atgaccttacaaccaaagagctttggatcaacatgccaattaagtgaaaaatttatcaaa
gctgcaattggctgtggtattgtagaaagcatactaaactgggtgaaatttaaggcccaa
gtccagttaaacaagaagtgttcagctgtaaaacataacagaatcaagggaattcccaaa
cttgatgatgccaatgatgcagggggccgaaactccactgattgtacacttatcctgact
gagggagactcagccaaaactttggctgtttcaggccttggtgtggttgggagagacaaa
tatggggttttccctctgagaggaaaaatgctcaatgttcgagaagcttctcataagcag
atcatggaaaatgctgagattaacaatatcatcaagattgtgggtcttcagtacaagaaa
aactatgaagatgaagattcactgaagactcttcgttatgggaagataatgattatgaca
gatcaggaccaagatggttcccacatcaaaggcttgctgattaattttatccatcacaac
tggccctctcttctgcgacatcgtttcctggaggaatttatcactcccattgtgaaggtg
tccaaaaacaagcaagaaatggcattttatagccttcctgaatttgaagaatggaagagt
tctactccaaattataaaaaatggaaagtcaaatattacaaaggtttgggtaccagcaca
tcaaaggaagctaaagaatattttgcagatatgaaaagacatcgtatccagttcaaatat
tctggtcctgaagatgatgctgctatcagcctggcctttagcaaaaaacagatagatgat
cgaaaggaatggttaactaatttcatggaggatagaagacaacgaaagttacttggactt
cctgaggattacttgtatggacaaactaccacatatctgacatataatgacttcatcaac
aaggaacttatcttgttctcaaattctgataacgagagatctatcccttctatggtggat
ggtttgaaaccaggtcagagaaaggttttgtttacttgcttcaaacggaatgacaagcga
gaggtaaaggttgcccagttagctggatcagtggctgaaatgtcttcttatcatcatggt
gagatgtcactaatgatgaccattatcaatttggctcagaattttgtgggtagtaataat
ctgaacctcttgcagcccattggtcagtttggtaccaggctacatggtggcaaggattcc
gctagtccacgatacatcttcacaatgctcagctctttggctcggttgttatttccacca
aaagatgatcacacattgaagtttttatatgacgacaaccagcgtgttgagcctgaatgg
tacattcctattattcccatggtgctgataaatggtgctgaaggaattggtaccgggtgg
tcctgcaaaatccccaactttgatgtacgtgaagttgtaaataacatcaggcgtttgatg
gatggagaagaacctttgccaatgcttccaagttacaagaacttcaagggtactattgaa
gaactggctccaaatcaatatgtgattagtggtgaagtagctattcttaattccacaacc
attgaaatctcagagcttcccatcagaacatggacccagacatacaaagaacaagttcta
gaacccatgttgaatggcactgagaagacacctcctctcataacagactatagggaatac
catacagataccactgtgaaatttgttgtgaagatgactgaagaaaaactggcagaggca
gagagagttggactacacaaagtcttcaaactccaaactagtctcacatgcaactctatg
gtgctttttgaccacgtaggctgtttaaagaaatatgacacggtgttggatattctaaga
gacttttttgaactcagacttaaatattatggattaagaaaagaatggctcctaggaatg
cttggtgctgaatctgctaaactgaataatcaggctcgctttatcttagagaaaatagat
ggcaaaataatcattgaaaataagcctaagaaagaattaattaaagttctgattcagagg
ggatatgattcggatcctgtgaaggcctggaaagaagcccagcaaaaggttcctgatgaa
gaagaaaatgaagagagtgacaatgaaaaggaaactgaaaagagtgactctgtaacagat
tctggaccaaccttcaactatcttcttgatatgcccctttggtatttaaccaaggaaaag
aaagatgaactctgcagactaagaaatgaaaaagaacaagagctggacacattaaagaga
aagagtccatcagatttgtggaaagaagacttggctacatttattgaagaactggaggct
gttgaagccaaggagaaacaagatgaacaagttggacttcctgggaaaggggggaaggcc
aaggggaaaaaaacacaaatggctgaagttttgccttctccatgtggtcaaagagtcatt
ccgcgaataaccatagaaatgaaagcagaggcagaaaagaaaaataaaaagaaaattaag
aatgaaaatactgaaggaagccctcaagaagatggtatggaactagaaggcctaaaacaa
agattagaaaagaaacagaaaagagaaccaggtacaaagacaaagaaacaaactacattg
ccatttaagccaatcaaaaaaggaaagaagagaaatccctggtctgattcagaatcagat
aggagcagtgacgaaagtaattttgatgtccctccacgagaaacagagccacgaagagca
gcaacaaaaaccaaattcacagtggatttggattcagatgaagatttctcagattttgat
gaaaaaactgatgatgaagattttgtcccatcagatgctagtccacctaagaccaaaact
tccccaaaacttactaacaaagatctgaaaccacagaaaagtgctatgtcagaccttgaa
gctgatgatgctaaggacagtgtaccactgtcttcaagccctcctgctacacatttccca
aatgaaactgaaattacaaacacagttcctaaaaagaatgtgacagtgaagaagacagca
gcaaaaagtcagtcttccacctccactaccggtgccaaaaaaagggctgcccctaaagga
actaaaaaggaaccagctttgaattctggtatctctcaaaagcctgatcctgccaaaacc
aagattcgccgcaaaaggaagccatccacttctgatgattctgactctaattttgagaaa
attgtttcgaaagcagtcacaagcaagaaatccaggggggagagtgatgacttccatatg
gactttgactcagctgtggctcctcgggcaaaatctgtgcgggcaaagaaacctataaag
tacctggaagagtcagatgaagatgatctgttttaa
DBGET
integrated database retrieval system
