Macaca nemestrina (pig-tailed macaque): 105474624 Help Entry 105474624         CDS       T08765                                  Symbol RYR2 Name (RefSeq) ryanodine receptor 2   KO K04962   ryanodine receptor 2 Organism mni  Macaca nemestrina (pig-tailed macaque) Pathway mni04020   Calcium signaling pathway mni04024   cAMP signaling pathway mni04260   Cardiac muscle contraction mni04261   Adrenergic signaling in cardiomyocytes mni04371   Apelin signaling pathway mni04713   Circadian entrainment mni04911   Insulin secretion mni04921   Oxytocin signaling pathway mni04972   Pancreatic secretion mni05020   Prion disease mni05022   Pathways of neurodegeneration - multiple diseases mni05410   Hypertrophic cardiomyopathy mni05412   Arrhythmogenic right ventricular cardiomyopathy mni05414   Dilated cardiomyopathy mni05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:mni00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     105474624 (RYR2)    04020 Calcium signaling pathway     105474624 (RYR2)    04024 cAMP signaling pathway     105474624 (RYR2)  09150 Organismal Systems   09152 Endocrine system    04911 Insulin secretion     105474624 (RYR2)    04921 Oxytocin signaling pathway     105474624 (RYR2)   09153 Circulatory system    04260 Cardiac muscle contraction     105474624 (RYR2)    04261 Adrenergic signaling in cardiomyocytes     105474624 (RYR2)   09154 Digestive system    04972 Pancreatic secretion     105474624 (RYR2)   09159 Environmental adaptation    04713 Circadian entrainment     105474624 (RYR2)  09160 Human Diseases   09164 Neurodegenerative disease    05020 Prion disease     105474624 (RYR2)    05022 Pathways of neurodegeneration - multiple diseases     105474624 (RYR2)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     105474624 (RYR2)    05412 Arrhythmogenic right ventricular cardiomyopathy     105474624 (RYR2)    05414 Dilated cardiomyopathy     105474624 (RYR2)    05415 Diabetic cardiomyopathy     105474624 (RYR2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:mni04040]     105474624 (RYR2)    04990 Domain-containing proteins not elsewhere classified [BR:mni04990]     105474624 (RYR2) Ion channels [BR:mni04040]  Voltage-gated cation channels   Ryanodine receptor    105474624 (RYR2) Domain-containing proteins not elsewhere classified [BR:mni04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    105474624 (RYR2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8 Motif Other DBs NCBI-GeneID:  105474624 NCBI-ProteinID:  XP_011727740 Ensembl:  ENSMNEG00000006610 LinkDB All DBs Position Unknown AA seq 4967 aa AA seqDB search MADGGEGEDEIQFLRTDDEVVLQCTATIHKEQQKLCLAAEGFGNRLCFLESTSNSKNVPP DLSICTFVLEQSLSVRALQEMLANTVEKSEGQVDVEKWKFMMKTAQGGGHRTLLYGHAIL LRHSYSGMYLCCLSTSRSSTDKLAFDVGLQEDTTGEACWWTIHPASKQRSEGEKVRVGDD LILVSVSSERYLHLSYGNGSLHVDAAFQQTLWSVAPISSGSEAAQGYLIGGDVLRLLHGH MDECLTVPSGEHGEEQRRTVHYEGGAVSVHARSLWRLETLRVAWSGSHIRWGQPFRLRHV TTGKYLSLMEDKNLLLMDKEKADVKSTAFTFRSSKEKLDVGVRKEVDGMGTSEIKYGDSV CYIQHVDTGLWLTYQSVDVKSVRMGSIQRKAIMHHEGHMDDGISLSRSQHEESRTARVIR STVFLFNRFIRGLDALSKKAKATTVDLPIESVSLSLQDLIGYFHPPDEHLEHEDKQNRLR ALKNRQNLFQEEGMINLVLECIDRLHVYSSAAHFADVAGREAGESWKSILNSLYELLAAL IRGNRKNCAQFSGSLDWLISRLERLEASSGILEVLHCVLVESPEALNIIKEGHIKSIISL LDKHGRNHKVLDVLCSLCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSSMRPNIF LGVSEGSAQYKKWYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGD DLFSYGFDGLHLWSGCIARTVSSPNQHLLRTDDVISCCLDLSAPSISFRINGQPVQGMFE NFNIDGLFFPVVSFSAGIKVRFLLGGRHGEFKFLPPPGYAPCYEAVLPKEKLKVEHSREY KQERTYTRDLLGPTVSLTQAAFTPIPVDTSQIVLPPHLERIREKLAENIHELWVMNKIEL GWQYGPVRDDNKRQHPCLVEFSKLPEQERNYNLQMSLETLKTLLALGCHVGISDEHAEDK VKKMKLPKNYQLTSGYKPAPMDLSFIKLTPSQEAMVDKLAENAHNVWARDRIRQGWTYGI QQDVKNRRNPRLVPYTLLDDRTKKSNKDSLREAVRTLLGYGYNLEAPDQDHAARAEVCSG TGERFRIFRAEKTYAVKAGRWYFEFETVTAGDMRVGWSRPGCQPDQELGSDERAFAFDGF KAQRWHQGNEHYGRSWQAGDVVGCMVDMNEHTMMFTLNGEILLDDSGSELAFKDFDVGDG FIPVCSLGVAQVGRMNFGKDVSTLKYFTICGLQEGYEPFAVNTNRDITMWLSKRLPQFLQ VPSNHEHIEVTRIDGTIDSSPCLKVTQKSFGSQNSHTDIMFYRLSMPIECAEVFSKTVAG GLPGAGLFGPKNDLEDYDADSDFEVLMKTAHGHLVPDRVDKDKEATKPEFNNHKDYAQEK PSRLKQRFLLRRTKPDYSTSHSARLTEDVLADDRDDYDFLMQTSTYYYSVRIFPGQEPAN VWVGWITSDFHQYDTGFDLDRVRTVTVTLGDEKGKVHESIKRSNCYMVCAGESMSPGQGR NNNGLEIGCVVDAASGLLTFIANGKELSTYYQVEPSTKLFPAVFAQATSPNVFQFELGRI KNVMPLSAGLFKSEHKNPVPQCPPRLHVQFLSHVLWSRMPNQFLKVDVSRISERQGWLVQ CLDPLQFMSLHIPEENRSVDILELTEQEELLKFHYHTLRLYSAVCALGNHRVAHALCSHV DEPQLLYAIENKYMPGLLRAGYYDLLIDIHLSSYATARLMMNNEYIVPMTEETKSITLFP DENKKHGLPGIGLSTSLRPRMQFSSPSFVSVSNECYQYSPEFPLDILKAKTIQMLTEAVK EGSLHARDPVGGTTEFLFVPLIKLFYTLLIMGIFHNEDLKHILQLIEPSVFKEAATPEEE SDTLEKELSVDDAKLQGAGEEEAKGGKRPKEGLLQMKLPEPVKLQMCLLLQYLCDCQVRH RIEAIVAFSDDFVAKLQDNQRFRYNEVMQALNMSAALTARKTKEFRSPPQEQINMLLNFK DDKSECPCPEEIRDQLLDFHEDLMTHCGIELDEDGSLDGNSDLTIRGRLLSLVEKVTYLK KKQAEKPVESDSKKSSTLQQLISETMVRWAQESVIEDPELVRAMFVLLHRQYDGIGGLVR ALPKTYTINGVSVEDTINLLASLGQIRSLLSVRMGKEEEKLMIRGLGDIMNNKVFYQHPN LMRALGMHETVMEVMVNVLGGGESKEITFPKMVANCCRFLCYFCRISRQNQKAMFDHLSY LLENSSVGLASPAMRGSTPLDVAAASVMDNNELALALREPDLEKVVRYLAGCGLQSCPLL VSKGYPDIGWNPVEGERYLDFLRFAVFCNGESVEENANVVVRLLIRRPECFGPALRGEGG NGLLAAMEEAIKIAEDPSRDGPSPNSGSSKTLDTEEEEDDTIHMGNAIMTFYAALIDLLG RCAPEMHLIHAGKGEAIRIRSILRSLIPLGDLVGVISIAFQMPTIAKDGNVVEPDMSAGF CPDHKAAMVLFLDRVYGIEVQDFLLHLLEVGFLPDLRAAASLDTAALSATDMALALNRYL CTAVLPLLTRCAPLFAGTEHHASLIDSLLHTVYRLSKGCSLTKAQRDSIEVCLLSICGQL RPSMMQHLLRRLVFDVPLLNEHAKMPLKLLTNHYERCWKYYCLPGGWGNFGAASEEELHL SRKLFWGIFDALSQKKYEQELFKLALPCLSAVAGALPPDYMESNYVSMMEKQSSMDSEGN FNPQPVDTSNITIPEKLEYFINKYAEHSHDKWSMDKLANGWIYGEIYSDSSKVQPLMKPY KLLSEKEKEIYRWPIKESLKTMLAWGWRIERTREGDSMALYNRTRRISQTSQVSVDAAHG YSPRAIDMSNVTLSRDLHAMAEMMAENYHNIWAKKKKMELESKGGGNHPLLVPYDTLTAK EKAKDREKAQDILKFLQINGYAVSRGFKDLELDTPSIEKRFAYSFLQQLIRYVDEAHQYI LEFDGGSRGKGEHFPYEQEIKFFAKVVLPLIDQYFKNHRLYFLSAASRPLCSGGHASNKE KEMVTSLFCKLGVLVRHRISLFGNDATSIVNCLHILGQTLDARTVMKTGLESVKSALRAF LDNAAEDLEKTMENLKQGQFTHTRNQPKGVTQIINYTTVALLPMLSSLFEHIGQHQFGED LILEDVQVSCYRILTSLYALGTSKSIYVERQRSALGECLAAFAGAFPVAFLETHLDKHNI YSIYNTKSSRERAALSLPTNVEDVCPNIPSLEKLMEEIVELAESGIRYTQMPHVMEVILP MLCSYMSRWWEHGPENNPERAEMCCTALNSEHMNTLLGNILKIIYNNLGIDEGAWMKRLA VFSQPIINKVKPQLLKTHFLPLMEKLKKKAAMVVSEEDHLKAEARGDMSEAELLILDEFT TLARDLYAFYPLLIRFVDYNRAKWLKEPNPEAEELFRMVAEVFIYWSKSHNFKREEQNFV VQNEINNMSFLITDTKSKMSKAAVSDQERKKMKRKGDRYSMQTSLIVAALKRLLPIGLNI CAPGDQELIALAKNRFSLKDTEDEVRDIIRSNIHLQGKLEDPAIRWQMALYKDLPNRTDD TSDPEKTVERVLDIANVLFHLEQKSKRVGRRHYCLVEHPQRSKKAVWHKLLSKQRKRAVV ACFRMAPLYNLPRHRAVNLFLQGYEKSWIETEEHYFEDKLIEDLAKPGADPPEEDEGTKR VDPLHQLILLFSRTALTEKCKLEEDFLYMAYADIMAKSCHDEEDDDGEEEVKSFEEKEME KQKLLYQQARLHDRGAAEMVLQTISASKGETGPMVAATLKLGIAILNGGNSTVQQKMLDY LKEKKDVGFFQSLAGLMQSCSVLDLNAFERQNKAEGLGMVTEEGSGEKVLQDDEFTCDLF RFLQLLCEGHNSDFQNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDVIDE QGQRNFSKAIQVAKQVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSQ DSSQIELLKELMDLQKDMVVMLLSMLEGNVVNGTIGKQMVDMLVESSNNVEMILKFFDMF LKLKDLTSSDTFKEYDPDGKGVISKRDFHKAMESHKHYTQSETEFLLSCAETDENETLDY EEFVKRFHEPAKDIGFNVAVLLTNLSEHMPNDTRLQTFLELAESVLNYFQPFLGRIEIMG SAKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEKEKMELFVNFCEDTIFEM QLAAQISESDLNERSANKEESEKERPEEQGPRMAFFSILTVKSALFALRYNILTLMRMLS LKSLKKQMKKVKKMTVKDMVTAFFSSYWSIFMTLLHFVASVFRGFFRIICSLLLGGSLVE GAKKIKVAELLANMPDPTQDEVRGDGEEGERKTLEAALPSEDLTDLKELTEESDLLSDIF GLDLKREGGQYKLIPHNPNAGLSDLMSNPVPMPEVQEKFQEQKAKEEEKEEKEETKSEPE KAEGEDGEKEEKAKEDKGKQKLRQLHTHRYGEPEVPESAFWKKIIAYQQKLLNYFARNFY NMRMLALFVAFAINFILLFYKVSTSSVVEGKELPTRSSSENAKVTSLDSSSHRIIAVHYV LEESSGYMEPTLRILAILHTVISFFCIIGYYCLKVPLVIFKREKEVARKLEFDGLYITEQ PSEDDIKGQWDRLVINTQSFPNNYWDKFVKRKVMDKYGEFYGRDRISELLGMDKAALDFS DAREKKKPKKDSSLSAVLNSIDVKYQMWKLGVVFTDNSFLYLAWYMTMSVLGHYNNFFFA AHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDGD TPDMKCDDMLTCYMFHMYVGVRAGGGIGDEIEDPAGDEYEIYRIIFDITFFFFVIVILLA IIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTVPHGFETHTLQEHNLANYLF FLMYLINKDETEHTGQESYVWKMYQERCWEFFPAGDCFRKQYEDQLN NT seq 14904 nt NT seq  +upstreamnt  +downstreamnt atggccgatgggggcgagggcgaagacgagatccagttcctgcgaactgatgatgaagtg gttctgcagtgcaccgcaaccatccacaaagaacaacagaaactatgcttggcagcagaa ggatttggcaacagactttgtttcttggagtccacttccaattccaagaatgtgccccca gacctctccatctgcacctttgtgctggagcagtccctctctgtccgggccctgcaggag atgctggctaacaccgtggagaaatcagaagggcaagttgatgtggaaaaatggaaattc atgatgaagactgctcaaggtggtggtcatcgaacactcctctatggacatgccatattg ctgcgccattcctacagtggcatgtatctgtgctgcctgtccacctcccggtcttcaact gataagctggcttttgatgttggcttgcaagaggacaccacaggagaggcttgttggtgg accatacaccctgcctctaagcagcgatcagaaggagaaaaagtacgagttggagatgac ctcatcttagttagcgtgtcctctgaaaggtacttgcacttgtcttacggcaacggcagc ttacatgtggatgccgctttccagcagactctctggagcgtggccccaatcagctcagga agtgaggcagcccaagggtatctcattggtggtgatgtcctcaggttgctgcatggacac atggacgagtgtctcactgtcccttcaggagaacatggtgaagagcagcggagaactgtt cattacgaaggtggcgctgtgtctgttcatgcacgttccctttggagactagagacacta agagttgcgtggagtggaagccacataagatggggccagccgttccgactacgccatgtc acaacaggaaaatacttgagtctcatggaagacaaaaaccttctactcatggacaaagag aaagctgatgtaaaatcaacagcatttaccttccggtcttccaaggaaaaattggatgta ggggtgagaaaagaagtcgacggcatgggaacatctgaaataaaatacggtgactcagta tgctatatacaacatgtggacacgggcctatggcttacttaccagtctgtggatgtgaaa tctgtgagaatgggatctatacaacgtaaggctattatgcaccatgaaggccacatggat gatggcataagtttatcgagatcccagcatgaagaatcacgcacagcacgagttatccgg agcacagtcttccttttcaatagatttataaggggcctcgatgcgctcagcaagaaagca aaggctaccaccgtcgatttgccgatagaatccgtgagtctaagtctgcaggatctcatt ggctactttcacccgcccgatgagcatttagaacatgaagacaaacagaacagactacga gccctgaagaatcggcaaaatctcttccaggaagagggaatgatcaacctcgtgctcgag tgcatagaccgattgcacgtctacagcagtgcagcacactttgctgatgttgctgggcga gaagcaggggagtcttggaaatccattctgaattctctgtatgagttgctggcggctctt attagaggaaatcgtaaaaactgtgctcagttttccggctcccttgactggttgatcagc agattggaaagactggaagcttcttcgggcattctggaagttttacactgtgttttagta gaaagtccagaagctctaaatattattaaagaaggacatattaaatccattatctcactt ttagacaagcatggaagaaatcacaaggtcctggacgtgttgtgctcactctgtgtttgc catggggttgcagtccgttctaaccagcacctcatctgtgacaatctcttaccaggaaga gatctgttattgcagacacgtcttgtgaaccacgtcagcagcatgagacccaatattttt ctgggcgtcagtgaaggttctgctcagtataagaaatggtactatgaattgatggtggac cacacagagccctttgtgacagctgaagcaacgcacctgcgagtgggctgggcttccact gaagggtattctccctaccctggagggggcgaagagtggggtggaaatggtgttggagat gatctcttctcctatggatttgatggccttcatctctggtcaggttgtattgctcgtact gtaagctcaccaaaccaacatctgttaagaactgatgatgtcatcagttgctgtttagat ctaagtgccccaagcatctcgttccgaattaatggacaacctgttcaaggaatgtttgag aatttcaacatcgatggcctcttctttccagtcgttagtttctctgcgggaataaaagta cgctttctgcttggggggcgacatggagaattcaaatttcttcctccacccgggtacgct ccttgttatgaagctgttctgccaaaagaaaagttgaaagtggaacacagccgagagtac aagcaagaaagaacttacacacgcgacctgctgggccccacggtttccctgacacaagct gccttcacaccgatccctgtggataccagccagattgtgttgcctcctcatctagaaaga ataagagaaaaactggcagagaatatccatgaactctgggttatgaataaaattgagctt ggctggcagtatggaccggttagagatgacaacaagagacagcacccatgcctggtggag ttctccaagctgcctgaacaggagcgcaattacaacttacaaatgtcgcttgagaccctg aagactttgttggcattaggatgtcatgtgggtatatcagatgaacatgctgaagacaag gtgaaaaaaatgaagctacccaagaattaccagctgacaagtggatacaagcccgcccct atggacctgagctttatcaaactcaccccgtctcaagaagcaatggtggacaagttggca gaaaatgcacacaatgtgtgggcacgggatcgaatccggcagggctggacttacggcatc cagcaggacgtaaagaacagaagaaatccccgccttgttccctacactcttctggatgac cgaaccaagaaatccaacaaggacagcctccgcgaggccgtgcgcacgctgctggggtac ggttacaacttggaagcaccagatcaagaccatgcagccagagccgaagtgtgcagcggc actggggaaaggttccgaatcttccgtgccgagaagacttacgcagtgaaggcgggacgg tggtattttgaatttgagacggtcactgctggagacatgagagttggttggagtcggcct ggttgtcaaccggatcaggagctcggctcggatgaacgtgcctttgcctttgatggcttc aaggcccagcggtggcatcagggcaacgaacactatgggcgctcttggcaagcaggcgat gtcgtgggctgtatggttgacatgaacgaacacaccatgatgttcacactgaatggtgaa atccttcttgatgattcaggttcagaactggctttcaaggactttgatgttggcgacgga ttcatacctgtgtgtagccttggagtggctcaagtgggcaggatgaactttggaaaggat gtcagcaccttgaaatacttcaccatctgtggcttacaagagggctatgaaccatttgcc gttaatacaaacagggatattactatgtggctgagcaagaggcttcctcagtttctccaa gttccatcaaaccatgaacatatagaggtgaccagaatagacggcaccatagacagttcc ccatgtttaaaggtcactcagaagtcttttggttctcagaacagccacactgatatcatg ttctatcgcctgagcatgccgatcgagtgcgcggaggtcttctccaagactgtggctgga gggctccctggggctggcctttttgggcccaagaatgatttggaagattatgatgctgat tctgactttgaggttctgatgaagacagctcatggccatctagtgcccgatcgtgttgac aaagacaaagaagctaccaagccagagtttaataaccacaaagattatgcccaggaaaag ccctctcgtctgaaacaaagatttttgcttagaagaacaaagccagattatagcacgagc cattctgcaagactcaccgaagatgtccttgctgatgatcgggatgattatgatttcttg atgcaaacgtccacgtactattactcagtgagaatcttccctggacaagaacctgctaat gtctgggtgggctggattacatcggatttccatcagtatgacacaggctttgacttggac agagttcgcacagtaacagttactctaggagatgaaaaaggaaaagtgcatgaaagcatc aaacgcagcaactgctatatggtatgtgcgggtgagagcatgagccccgggcaaggacgc aacaataatggactggagatcggctgtgtggtggatgctgccagcgggctgctcacgttc attgccaatggcaaggaactgagcacatactatcaggtggagccgagtacaaaattattt cctgcggtttttgcacaagctacaagtcccaatgttttccagtttgagttgggaagaata aagaatgtgatgcctctctcggcgggattattcaagagtgagcacaagaaccccgtgccg cagtgtcccccgcgcctccacgtgcagttcctgtcacacgtgctgtggagcagaatgccc aaccagtttttgaaggtagatgtgtctcgaataagtgaacgccaaggctggttggtgcag tgtttggatcccctgcagttcatgtctcttcatatccctgaggaaaacagatctgttgac atcttggagttgacagagcaggaggagttgctgaaatttcactatcacactctgcggctc tactcagctgtctgtgctcttgggaaccaccgggtggcccacgccctgtgcagccacgtg gatgaacctcagctcctctacgccattgagaacaagtacatgcctggcttgctgcgtgct ggctactatgacctgctgatcgacatccacctgagctcctatgccactgccaggctcatg atgaacaacgagtacattgtccccatgacggaggagacgaagagcatcaccctgttccct gatgagaacaaaaagcatggccttccagggatcggcctcagcacctctctcaggccacgg atgcagttttcctcccccagttttgtaagtgttagtaatgaatgttaccagtatagtcca gagttcccactggacatcctcaaggccaagaccatacagatgctgacggaagctgttaaa gagggcagtcttcatgcccgggacccagttggagggactactgaattcctctttgtgcct ctcatcaagcttttctataccctgctaatcatgggcatcttccacaacgaggacttgaag cacatcttgcagcttatcgagcccagtgtgtttaaagaagcggccactccagaggaggag agtgatacactggagaaagagctcagtgtggatgacgcaaagctgcaaggagctggtgag gaagaagccaaggggggcaagcggcccaaggaaggcctgctccaaatgaaactgccagag ccagttaaattgcagatgtgcctactgcttcaatacctctgtgactgccaggtccggcac cggatagaagccattgtagccttttcagatgattttgtagctaagctccaagacaatcaa cgtttccgatacaacgaagttatgcaagccttaaacatgtcagctgcactcacagccagg aaaacaaaggaattcagatcaccacctcaagagcagatcaatatgcttctcaattttaag gatgacaaaagtgaatgtccgtgtccagaagaaattcgtgaccaactattggatttccat gaagatttgatgacgcattgtggaattgagctggatgaagatgggtctctggatggaaac agtgatttaacaattagagggcgtctgctatccctggtagaaaaggtgacatacctgaag aagaagcaagcagaaaaaccagttgagagtgactccaaaaagtcctccactctgcagcag ctgatctctgagaccatggtcagatgggctcaggagtctgtcattgaagaccccgagctg gtgagggccatgtttgtgttgctccatcggcagtatgatggcattgggggtcttgttcgg gccctgccaaagacctacacgataaatggtgtgtccgtggaggacaccatcaacctgctg gcgtcccttggtcagattcggtccctgctgagtgtgagaatgggcaaagaagaggagaag cttatgattcgcggattaggggatattatgaataacaaggtgttttaccagcaccctaat ctcatgagggcactggggatgcatgagactgtgatggaggtcatggtgaacgtccttgga ggtggagagtccaaggaaatcacctttcccaagatggtggccaactgttgccgttttctc tgttacttctgtcgtataagtaggcagaatcaaaaagctatgtttgatcatctcagttat ttactggaaaacagcagtgttggtcttgcctccccagctatgagaggttcaacaccactg gatgtggctgcagcttcggtgatggataataatgaactagcattagctctgcgtgagccg gatctagaaaaggtagttcgttacttggctggttgtggactgcagagctgcccgttgctg gtgtctaagggttacccagacattgggtggaatccagttgaaggagagagataccttgac tttctcagatttgctgtcttctgtaatggggagagtgtggaggagaatgcaaatgtcgtg gtgagattgcttattcggaggcctgagtgttttggtcctgctttgagaggagaaggtggg aatgggcttcttgcagcaatggaagaagccatcaaaatcgccgaggatccttctcgagat ggtccctcaccaaatagcggatccagtaaaacacttgatacagaggaggaggaagatgac actatccacatggggaacgcgatcatgaccttctatgcagctttgattgacctcttggga cgctgtgcgcctgagatgcatttgattcatgctggtaagggagaagccatcagaattagg tctattttgagatctctaattcccttgggagatttggtgggcgttatcagcatcgctttt cagatgccaacaatagccaaagatgggaatgtggtggaacctgacatgtctgcggggttt tgcccagatcacaaggcagccatggttttattccttgacagggtctatggaattgaggtt caagacttcctcctccatcttcttgaggttggctttctgccagatctccgggcggctgct tctttagatacggcggctttgagtgctacagacatggccttggccctcaatcggtacctt tgcacggccgtcttgccgttgctaacaagatgtgctcctctctttgctggcacagagcac catgcttctctcattgactcattgcttcatactgtatatagactttctaagggctgttca cttaccaaagctcagcgggattctatagaagtttgtttgctctctatttgtggacaactg agaccttctatgatgcagcacttactcagaagattagtatttgatgttccattattaaat gaacatgcaaagatgcctcttaaactgctgacaaatcattatgaaagatgctggaaatat tactgcctgcctggagggtggggaaactttggtgctgcctcagaagaagaacttcattta tcgagaaagttgttctggggcatttttgatgccctgtctcaaaagaaatatgaacaagag cttttcaaactggcactgccttgcctgagtgcagttgcgggagctttgcctccagactac atggagtcaaattatgtcagtatgatggaaaaacagtcatcaatggattctgaagggaac tttaacccacaacctgttgatacctcaaatattacaattcctgagaagttggaatacttc attaacaaatatgcagaacactcgcatgacaaatggtcaatggacaagttggcaaatgga tggatttatggagaaatatattcagactcttctaaggttcaaccattaatgaagccatac aagctattgtctgaaaaggaaaaagaaatttatcgctggccaatcaaagaatctttaaaa actatgctggcttggggctggagaattgaaagaactcgagagggagacagcatggccctt tacaaccggactcgtcgtatttctcagacaagccaggtttctgtagacgctgcccatggt tacagtccccgggccattgacatgagcaatgttacgctatctagagacctgcatgctatg gcagaaatgatggctgaaaactaccataatatatgggcaaagaaaaagaaaatggagttg gagtccaaaggaggaggtaaccaccctctgctggtgccctatgatacactgacagccaaa gagaaagccaaggatagagaaaaagcacaggacatcctcaagttcttgcagatcaatgga tatgctgtatccagaggatttaaggacctggaactggacacgccttctattgagaaacga tttgcctacagtttcctccaacaactcattcgctatgtggatgaagcccatcagtatatc ctggagtttgatggtggcagcagaggcaaaggagaacatttcccttatgaacaagaaatc aagttctttgcaaaagtcgttcttcctttaattgatcagtatttcaaaaaccatcgttta tacttcttatctgcagcaagcagacctctctgctctggaggacatgcttccaacaaagag aaagaaatggtgactagcctattctgcaaacttggagttcttgtcaggcataggatttca ctatttggcaatgatgcaacatcaattgtcaactgtcttcatattttgggtcagactctg gatgcaaggacagtgatgaagactggcctggagagtgttaaaagtgcactcagagctttt ctggacaatgccgcagaggatctggagaagaccatggaaaacctcaagcagggccagttc actcacacccgaaaccagcccaaaggggttactcagattatcaattacaccacagtggcc ctgcttccaatgctgtcgtcattatttgaacatattggccagcatcagttcggagaagac ctcatattggaagatgtccaggtgtcttgttatagaattctgactagcttatatgctttg ggaaccagcaagagtatttatgtggagaggcaacgttctgcattaggagaatgtcttgct gcgtttgctggtgcctttcctgtagcatttttggaaactcatctggacaaacataatatt tactccatctacaataccaagtcttcacgagaaagagcagctctcagtttgccaactaat gtggaagatgtttgtccaaatataccgtctttggagaaactcatggaagaaatcgtggaa ttagctgagtccggcattcgctacactcaaatgccacatgtgatggaagtcatactgccc atgctttgcagctacatgtctcgttggtgggagcatgggcctgagaacaatccagaacgg gccgagatgtgctgcacagccctgaactcagagcacatgaacacacttctagggaacata ttgaaaatcatatataataacttggggattgatgagggagcctggatgaagaggctagca gtgttttcccagcctataataaataaagtgaaacctcagctcttgaaaactcatttcttg ccgttaatggagaaactcaagaaaaaggcagccatggtggtgtctgaggaagaccacctg aaagccgaggccaggggggacatgtcagaggctgaactcctcatcctagatgagttcacc acgctggccagagatctctatgccttctaccctctcttgattagatttgtggactataac agggcaaagtggctgaaggagcctaacccggaagcagaggagctcttccgcatggtggca gaagtgtttatctactggtcgaaatcccataatttcaaaagagaagagcagaacttcgtt gtacagaatgaaatcaacaatatgtctttccttattactgataccaagtccaagatgtcc aaggcagcggtttctgatcaggaaaggaagaaaatgaagcgcaaaggagatcggtattcc atgcagacctctctgattgtagcagctctgaagcgcttactgcccattgggttgaacatc tgtgccccaggggaccaggagctcattgctctagccaaaaatcgatttagcctgaaagat actgaggatgaagtacgagatataatccgcagcaatattcatttacaaggcaagttggag gatcctgctattagatggcaaatggctctttacaaagacttgccaaacaggactgatgat acctcagatccagagaagacggtagaaagagtattggatatagcaaatgtgctttttcat cttgaacagaagtctaaacgtgtgggtcggagacattactgtctggtggaacatcctcag agatctaaaaaggctgtatggcataaactactctctaagcagaggaaaagagctgttgtc gcctgcttccggatggcccccttatataatctgccaaggcatcgggctgtcaatctcttt cttcagggatatgaaaagtcttggattgaaacagaagaacattactttgaagataaactg atagaagatttagcaaaacctggggctgaccctccagaagaagatgaaggcactaagaga gttgatcctctacatcagctgatccttctgtttagtcggacagctttaacagagaaatgc aaactggaggaagattttttatatatggcctatgcagatattatggcaaagagttgtcat gatgaggaagatgatgacggggaagaggaagtgaagagttttgaagaaaaagaaatggaa aagcaaaagcttctataccagcaagcccgactccacgaccgtggtgcggctgagatggtg ctgcagaccatcagtgccagcaaaggtgaaactggaccaatggtagcagctactttgaaa cttggaattgctattttaaatggtgggaactccacagtacagcagaaaatgcttgactac ctcaaggagaaaaaggatgtgggcttctttcagagcctggctggcctgatgcagtcatgt agtgtccttgacctaaatgcatttgagcgacaaaacaaagctgaaggtcttgggatggtg acagaggaaggatcaggagaaaaggttctacaggacgatgagttcacctgtgacctcttc cgattcctgcagctactctgtgagggacacaactcagattttcagaattatctgagaact cagactggcaataatacaactgtcaacataatcatctccactgtagactacctactgaga gttcaggaatcaattagtgacttttactggtattactctgggaaagatgttattgatgaa caaggacaacggaatttctccaaagctattcaagtggcaaaacaagtctttaacactctt acagagtatattcagggtccttgcactgggaatcaacagagtttggcacacagcaggctg tgggatgctgtggtcggctttcttcatgtatttgcccatatgcagatgaagctgtcgcag gattccagtcagattgagcttttaaaagaattaatggatctgcagaaggatatggtggtc atgttgctgtccatgctagaaggtaatgttgttaacggaacgattggcaaacagatggtg gatatgcttgtggaatcttccaacaatgtggagatgattctcaaattttttgacatgttc ttaaaactgaaagatttgacgtcgtctgatacttttaaagaatatgaccccgatggcaag ggagtcatttccaagagggacttccacaaagcgatggagagtcataagcactacacgcag tcagaaacggaatttcttttgtcttgtgcggagacggatgagaatgaaacccttgactat gaggagttcgtcaaacgcttccacgaacctgcaaaggacatcggcttcaatgtcgccgtc cttctgacaaacctctctgagcacatgcccaacgatacccgacttcagactttcctagaa ttagcagagagtgtcctgaattatttccagccctttctgggccgcatcgaaatcatggga agcgccaaacgcatcgagagagtctattttgaaatcagtgagtctagccgaacccagtgg gagaagccccaggtcaaggagtccaaacgacagttcatatttgatgtggtcaatgaagga ggagaaaaagagaagatggaactctttgtgaacttctgcgaggacaccatctttgaaatg cagctggcggctcagatctcagagtcggatttgaacgagaggtcagcgaataaggaagaa agtgagaaggagaggccggaagagcaggggccgagaatggctttcttctccattctgacg gtcaagtcggccctgtttgcgctcaggtacaatatcttgacccttatgcgaatgctcagt ctgaagagcctgaagaagcagatgaaaaaagtcaaaaagatgaccgtgaaggacatggtc acggccttcttttcatcctactggagtatttttatgaccctcttgcacttcgtggccagc gttttcagaggctttttccgcatcatttgcagcctgctgcttgggggaagcctcgtcgaa ggtgctaaaaagatcaaagttgcagaactcttagccaacatgccagaccccactcaggat gaggttagaggagatggggaggagggagagaggaaaaccctggaagccgccctgccctct gaggatctgaccgacttaaaggagctgacagaggagagtgaccttctttcggacatcttc ggcctggatctgaagagagaaggaggacagtacaaactaatccctcataatccaaatgct gggctcagtgacctcatgagcaacccagtccccatgcctgaggtgcaagaaaaatttcag gaacagaaggcaaaagaagaagaaaaggaagaaaaagaagaaaccaaatctgaacctgaa aaagccgagggagaagatggagaaaaagaagagaaagccaaggaagacaagggcaaacaa aagttgaggcagcttcacacacacagatacggagaaccggaagtgcccgagtcagcgttc tggaagaaaatcatagcataccaacagaaacttctaaactattttgctcgcaacttttac aacatgagaatgttagccttatttgttgcatttgctatcaatttcatcttgctcttttat aaggtctccacttcttctgtggttgaaggaaaggagctccccactagaagttcaagtgaa aatgccaaagtgaccagcctggacagcagctcccatagaatcatcgcagttcactatgta ctggaggagagcagtggctacatggagcccacgttgcgtatcttagctattctccacacg gtcatttccttcttctgcatcattggatactactgcttgaaagtcccattggttattttt aagcgagaaaaggaagtagcacggaaattggaatttgatgggctttatattacagaacag ccttcagaagatgatattaaaggccagtgggatagactcgtaatcaacacacagtcattt cccaacaactactgggacaaatttgttaaaagaaaggtaatggataagtacggagagttc tacggccgagacagaattagtgaattacttggcatggacaaggcagctctggacttcagt gatgccagagaaaagaagaagccaaagaaagacagctccttatcagctgtactgaactct attgatgtgaagtatcagatgtggaaactaggagtcgttttcactgacaactccttcctc tacctagcctggtatatgactatgtctgttcttggacactataacaactttttttttgct gctcaccttctcgacattgctatgggattcaagacattaagaaccatcttgtcctcagta actcacaatggcaaacagctcgtattaactgttggcttgttagctgttgttgtgtacctg tacaccgtggtggcattcaattttttccgaaaattctacaataaaagtgaagacggtgat acaccagatatgaaatgtgatgatatgctaacgtgctatatgttccacatgtatgttgga gttcgtgccggaggagggatcggggatgaaatcgaagacccagcaggagatgaatatgag atctatcgaatcatctttgacatcactttcttcttctttgttattgtcattctcttggcc ataatacaaggtctaattatcgatgcttttggagaactaagagaccaacaggaacaagtc aaagaagacatggagaccaaatgcttcatctgtgggataggcaatgattacttcgacaca gtgccacatggctttgaaacccacactttacaggagcacaacttggctaattacttgttt tttctgatgtatcttataaacaaagacgaaacagaacacacaggacaggaatcttatgtc tggaagatgtatcaagaaaggtgctgggaatttttcccagcaggggattgtttccggaaa cagtatgaagaccagctaaattaa

DBGET integrated database retrieval system