Macaca nemestrina (pig-tailed macaque): 105474900
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Entry
105474900 CDS
T08765
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase, endothelial isoform X1
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
mni
Macaca nemestrina (pig-tailed macaque)
Pathway
mni00220
Arginine biosynthesis
mni00330
Arginine and proline metabolism
mni01100
Metabolic pathways
mni04020
Calcium signaling pathway
mni04022
cGMP-PKG signaling pathway
mni04066
HIF-1 signaling pathway
mni04071
Sphingolipid signaling pathway
mni04151
PI3K-Akt signaling pathway
mni04370
VEGF signaling pathway
mni04371
Apelin signaling pathway
mni04611
Platelet activation
mni04915
Estrogen signaling pathway
mni04921
Oxytocin signaling pathway
mni04926
Relaxin signaling pathway
mni04931
Insulin resistance
mni04933
AGE-RAGE signaling pathway in diabetic complications
mni05415
Diabetic cardiomyopathy
mni05417
Lipid and atherosclerosis
mni05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mni00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
105474900 (NOS3)
00330 Arginine and proline metabolism
105474900 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
105474900 (NOS3)
04371 Apelin signaling pathway
105474900 (NOS3)
04066 HIF-1 signaling pathway
105474900 (NOS3)
04020 Calcium signaling pathway
105474900 (NOS3)
04071 Sphingolipid signaling pathway
105474900 (NOS3)
04022 cGMP-PKG signaling pathway
105474900 (NOS3)
04151 PI3K-Akt signaling pathway
105474900 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
105474900 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
105474900 (NOS3)
04921 Oxytocin signaling pathway
105474900 (NOS3)
04926 Relaxin signaling pathway
105474900 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
105474900 (NOS3)
05418 Fluid shear stress and atherosclerosis
105474900 (NOS3)
05415 Diabetic cardiomyopathy
105474900 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
105474900 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
105474900 (NOS3)
Enzymes [BR:
mni01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
105474900 (NOS3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
DUF6285
Motif
Other DBs
NCBI-GeneID:
105474900
NCBI-ProteinID:
XP_011728085
Ensembl:
ENSMNEG00000024070
UniProt:
A0A2K6B252
LinkDB
All DBs
Position
Unknown
AA seq
1205 aa
AA seq
DB search
MGNLKSVAQEPGPPCGLGLGLGLGLCGKQGPATSAPEPSRAPASLPPPAPEHSPPSSPLT
QPPEGPKFPRVKNWEVGSIAYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAP
EQLLSQARDFINQYYSSIRRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRN
APRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGD
FRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPP
ELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMST
EIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDH
HAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPW
KGSAAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGR
LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSS
PRPEQHKSYKIRFNSISCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHF
CAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDAKAAA
RDIFSPKRSWKRQRYRLSAQAEGLQLLPGLIHVHRRKMFQATILSVENLQSSKSTRATIL
VRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPAPTEPVAVEQLEKGSPGGP
PPSWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEEPREQQELEALSQDPRRY
EEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSTHPGEIHLTVAVL
AYRTQDGLGPLHYGVCSTWLSQLKPGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAP
FRGFWQERLHDIESKGLQPTPMTLVFGCRCSQLDHLYRDEVQNAQQRGVFGRVLTAFSRE
PDNPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATNVLQTVQRILATEGDMELD
EAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWAFDPPGSDT
NTNGP
NT seq
3618 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagcgtggcccaggaacctgggccaccctgtggcctggggctgggg
ctgggccttgggctgtgcggcaagcagggcccagccacctcagcccctgagcccagccgg
gccccggcatccctacccccgccagcaccagaacacagccccccgagctccccgctaacc
cagcccccggaggggcccaagttccctcgtgtgaagaactgggaggtggggagcatcgcc
tatgacaccctcagcgcccaggcgcagcaggatgggccctgcaccccaagacgctgcctg
ggctccctggtatttccacggaaactacagggccggccctcccctggccccccggcccct
gagcagctgctgagtcaggcccgggacttcatcaaccagtactacagctccatcaggagg
agcggctcccaggcccacgaacagcggcttcaagaggtggaagccgaggtggcagccaca
ggcacctaccagcttagggagagcgagctcgtgttcggggccaagcaggcctggcgcaac
gctccccgctgtgtgggccggatccagtgggggaagctgcaggtgttcgatgcccgggac
tgcaggtctgcacaggaaatgttcacctacatctgcaaccacatcaaatacgccaccaac
cggggcaaccttcgctcggccatcacagtgttcccgcagcgctgccctggccgaggagac
ttccgaatctggaacagccagctggtgcgctatgcgggctaccggcagcaggacggctct
gtgcggggggacccagccaacgtcgagatcaccgagctctgcattcagcatggctggacc
ccaggaaacggtcgctttgacgtgcttcccctgctgctgcaggccccggatgagccccca
gaactcttccttctgccccctgagctggtccttgaggtgcccctggagcaccctacgctg
gagtggtttgcagccctgggcctgcgctggtacgccctcccagcagtgtccaacatgctg
ctggaaattgggggcctggagttccccgcagcccccttcagtggctggtacatgagcact
gagatcggcacgaggaacctgtgtgaccctcaccgctacaacatcctggaggacgtggct
gtctgcatggacctggatacccggacaacttcgtccctatggaaagacaaggcagcggtg
gaaatcaacgtggccgtgctgcacagttaccagctggccaaagtcaccattgtggaccac
cacgccgccacagcctccttcatgaagcacctggagaatgagcagaaggccagggggggc
tgccctgcagactgggcctggatcgtgccccccatctcgggcagcctcactcctgtcttc
catcaggagatggtcaactatttcctgtcaccagccttccgctaccagccagacccctgg
aaggggagtgcggccaagggcaccggcatcaccaggaagaagacctttaaagaagtggcc
aatgccgtgaagatctctgcctcgctcatgggcaccgtgatggcgaagcgagtgaaggcg
acaatcctgtatggctccgagaccggccgggcccagagctacgcacagcagctggggaga
cttttccggaaagcttttgatccccgggtcctgtgtatggatgagtatgacgtggtgtcc
ctcgaacacgagacgctggtgctggtggtaaccagcacattcgggaatggggatcccccg
gagaatggagagagctttgcagctgccctgatggagatgtccggtccctacaacagctcc
cctcggccggaacagcacaagagttataagatccgcttcaacagcatctcctgctcagac
ccactggtgtcctcttggcggcggaagaggaaggagtccagtaacacagacagtgcaggg
gccctgggcacactcaggttctgtgtgttcgggctgggctcccgggcctacccccacttc
tgcgcctttgctcgtgcggtggacacgcggctggaggaactgggcggggagcggctgctg
cagctgggccagggcgacgagctgtgtggccaggaggaggccttccgcggctgggcccag
gctgccttccaggccgcctgtgagaccttctgtgtgggagaggatgccaaggctgctgcc
cgagacatcttcagccccaaaaggagttggaagcgccagaggtaccggctgagcgcccag
gccgagggcctgcagttgctgccaggtctgatccacgtgcacaggcggaagatgttccag
gctacaattctctcagtggaaaacctgcaaagcagcaagtccacgagggccaccatcctg
gtgcgcctggacactggaggccaggaggggctgcagtaccagccgggggatcacataggt
gtctgcccacccaaccggcccggccttgtggaggcgctgctgagccgcgtggaggacccg
cctgcgcccaccgagcccgtggcagtagagcaactggagaagggcagccctggtggccct
ccccccagctgggtgcgggacccccggctgcccccatgcacgctgcgccaggctctcacc
ttcttcctggacatcacctccccgcccagccctcagctcttgcggctgctcagcaccttg
gcagaagagcccagggaacagcaggagctggaggccctcagtcaggatccccgacgctac
gaggagtggaagtggttccgctgccccacgctgctggaggtgctggagcagttcccgtcg
gtggcactgcctgccccactgctcctcacccagctgcctctgctccaaccccggtactac
tcagtcagctcagcacccagcacccacccaggagagatccacctcactgtagctgtgctg
gcatacaggacccaggatgggctgggccccctgcactatggagtctgctccacgtggcta
agccaactcaagcccggagaccctgtgccctgcttcatccggggggctccctccttccgg
ctgccacctgatcccagcttgccctgcatcctggtgggcccaggcactggcattgccccc
ttccggggattctggcaggagcggctgcatgacattgagagcaaagggctgcagcccact
cccatgactttggtgtttggctgccgatgctcccaactcgaccatctctaccgcgacgag
gtgcagaacgcccagcagcgcggggtgttcggccgagtcctcaccgccttctcccgggaa
cctgacaaccccaagacctacgtgcaggacatcctgaggacggagctggctgcggaggtg
caccgcgtgctgtgcctcgagcggggccacatgtttgtctgcggcgatgtcaccatggca
accaacgtcctgcagaccgtgcagcgcatcctggcaacggagggcgacatggagctggac
gaggccggcgacgtcatcggcgtgctgcgggatcagcaacgctaccacgaagacattttc
gggctcacgctgcgcacccaggaggtgacaagccgcatacgcacccagagcttttccttg
caggagcggcagctacggggcgcagtgccctgggcgttcgacccgcccggctcggacacc
aacaccaacggcccctga
DBGET
integrated database retrieval system
