KEGG   Macaca nemestrina (pig-tailed macaque): 105475450
Entry
105475450         CDS       T08765                                 
Symbol
ABCB1
Name
(RefSeq) multidrug resistance protein 1
  KO
K05658  ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2]
Organism
mni  Macaca nemestrina (pig-tailed macaque)
Pathway
mni02010  ABC transporters
mni04976  Bile secretion
mni05206  MicroRNAs in cancer
mni05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:mni00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    105475450 (ABCB1)
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    105475450 (ABCB1)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    105475450 (ABCB1)
  09162 Cancer: specific types
   05226 Gastric cancer
    105475450 (ABCB1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:mni02000]
    105475450 (ABCB1)
   04147 Exosome [BR:mni04147]
    105475450 (ABCB1)
   04090 CD molecules [BR:mni04090]
    105475450 (ABCB1)
Enzymes [BR:mni01000]
 7. Translocases
  7.6  Catalysing the translocation of other compounds
   7.6.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.6.2.2  ABC-type xenobiotic transporter
     105475450 (ABCB1)
Transporters [BR:mni02000]
 ABC transporters, eukaryotic type
  ABCB (MDR/TAP) subfamily
   ABCB1, 4, 5 subgroups
    105475450 (ABCB1)
Exosome [BR:mni04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   105475450 (ABCB1)
CD molecules [BR:mni04090]
 Proteins
  105475450 (ABCB1)
SSDB
Motif
Pfam: ABC_membrane ABC_tran SMC_N ABC_ATPase AAA_22 AAA_16 RsgA_GTPase Rad17 AAA_5 Zeta_toxin G-alpha AAA_29 AAA_7 AAA_14 DUF815 nSTAND1 AAA_15 NTPase_1 DUF2207_C
Other DBs
NCBI-GeneID: 105475450
NCBI-ProteinID: XP_011728984
Ensembl: ENSMNEG00000034486
UniProt: A0A2K6CD88
LinkDB
Position
Unknown
AA seq 1280 aa
MDLEGDRNGGAEKKNFFKLNNKSKKDKKERKPTVSVFSMFRYSNWLDKLYMVVGTLAAII
HGAGLPLMMLVFGDMTDTFANAGNLEALLSNNTNSSNITDTGPVMNLEEDMTRYAYYYSG
IGAGVLVAAYIQVSFWCLAAGRQIHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVS
KINEGIGDKIGMFFQSMATFFTGFIVGFTRGWKLTLVILAISPILGLSAAVWAKILSSFT
DKELLAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAITANISIG
AAFLLIYASYALAFWYGTTLVLSKEYSIGQVLTVFFSVLIGAFSVGQASPSIEAFANARG
AAFEIFKIIDNKPSIDSYSKSGHKPDNIKGNLEFRNVHFSYPSRKEVKILKGLNLKVQSG
QTVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDGQDIRTINVRFLREIIGVVSQEPVLF
ATTIAENIRYGREDVTMDEIEKAVKEANAYDFIMKLPQKFDTLVGERGAQLSGGQKQRIA
IARALVRNPKILLLDEATSALDTESEAVVQVALDKARKGRTTIVIAHRLSTVRNADVIAG
FDDGVIVEKGNHDELMKEKGIYFKLVTMQTAGNEIELENAADESKSEIDTLEMSSHDSGS
SLIRKRSTRRSVRGSQGQDRKLSTKEALDESIPPVSFWRIMKLNLTEWPYFVVGVFCAII
NGGLQPAFAVIFSKIIGIFTRNDDPETKQQNSNLFSLLFLVLGIVSFITFFLQGFTFGKA
GEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVITQNI
ANLGTGIIISLIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGAGKIATEA
IENFRTVVSLTQEQKFEHMYDQSLQVPYRNSLRKAHIFGITFSFTQAMMYFSYAGCFRFG
AYLVAHSLMSFEDVLLVFSAVVFGAMAVGQVSSFAPDYAKAKVSAAHIIMIIEKTPLIDS
YSTEGLKPNTLEGNVTFNEVVFNYPTRLDIPVLQGLSLEVKKGQTLALVGSSGCGKSTVV
QLLERFYDPLAGKVLLDGKEIKQLNVQWLRAHLGIVSQEPILFDCSISENIAYGDNSRVV
SQEEIVRAAKEANIHAFIESLPNKYSTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLD
EATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVFQNGRVKEHGTHQQL
LAQKGIYFSMVSVQAGAKRQ
NT seq 3843 nt   +upstreamnt  +downstreamnt
atggatcttgaaggggaccgcaatggaggagcagagaagaagaacttttttaaactgaac
aataaaagtaaaaaagataagaaggaaaggaaaccaactgtcagtgtattttcaatgttt
cgctattcaaattggcttgacaagttgtatatggtggtgggaactttggctgccatcatc
catggagctggacttcctctcatgatgctggtgtttggagacatgacggatacctttgca
aatgcaggaaatttagaagctctgttgtcaaacaacactaatagcagtaatatcactgat
acagggcccgtcatgaatctggaggaagatatgaccaggtatgcctattattacagtgga
attggtgctggggtgctggttgctgcttacattcaggtttcattttggtgcctggcagct
ggaagacaaatacacaaaattagaaaacagttttttcatgctataatgcgacaggagata
ggctggtttgatgtgcacgatgttggggagcttaacacccggcttacagatgatgtctcc
aagattaatgaaggaattggtgacaaaattggaatgttctttcagtcaatggcaacattt
ttcactgggtttatagtaggatttacacgtggttggaagctaacccttgtgattttggcc
atcagtcctattcttggactgtcagctgctgtctgggcaaagatactgtcttcatttact
gataaagaactcttagcttatgcaaaagctggagcagtagctgaagaggtcttggcagca
attagaactgtgattgcatttggaggacaaaagaaagaactcgaaaggtacaacaaaaat
ttagaagaagctaaaagaattgggataaagaaagctattacagccaatatttctataggt
gctgctttcctgcttatctatgcatcttatgctctggccttctggtatgggaccaccttg
gtcctctcaaaggaatattctattggacaagtactcactgtattcttttctgtattaatt
ggggcttttagtgttggacaggcatctccaagcattgaagcatttgcaaatgcaagagga
gcagcttttgaaatcttcaagataattgataataagccaagtattgacagctattcgaag
agtgggcacaaaccagataatattaagggaaatttggaattcagaaatgttcacttcagt
tacccatctcgaaaagaagttaagatcttgaagggcctgaacctgaaggtgcagagtggg
cagacggtggccctggttggaaacagcggctgtgggaagagcacaacggtccagctgatg
cagaggctttatgaccccacagagggcatggtcagtgttgatggacaggatattaggacc
ataaacgtaaggtttctacgggaaatcatcggtgtggtgagtcaggaacctgtattgttt
gccaccacgatagctgaaaacattcgctatggtcgtgaagatgtcaccatggatgagatt
gagaaagctgtcaaggaagccaatgcctatgactttatcatgaaactgcctcagaaattt
gacaccctggttggagagagaggggcccagctgagtggtgggcagaagcagaggatcgcc
attgcacgtgccctggttcgcaaccccaagatcctcctgctggacgaggccacgtcagcc
ttggacacagaaagtgaagcagtggttcaggtggctctggataaggccagaaaaggtcgg
accaccattgtgatagctcatcgtttgtctacggttcgtaatgccgacgtcatcgctggt
ttcgatgatggagtcattgtggagaaaggaaatcatgatgagctcatgaaagagaaaggc
atttacttcaaacttgtcacaatgcagacagcaggaaatgaaattgaattagaaaatgca
gctgatgaatccaaaagtgaaattgataccttggaaatgtcttcacatgattcaggatcc
agtctaataagaaaaagatccactcgtaggagtgtccgtggatcacaaggccaagacaga
aagcttagtaccaaagaggctctggatgaaagtatacctccagtttccttttggaggatt
atgaagctaaatttaactgagtggccttattttgttgttggtgtattttgtgccattata
aatggaggtctgcaaccagcatttgcagtaatattttcaaagattatagggatttttaca
agaaatgatgatcccgaaacaaaacaacagaatagtaacttgttttcactattgtttcta
gtccttggaattgtttcttttattacatttttccttcagggcttcacatttggcaaagct
ggagagatcctcaccaagcggctccgatacatggttttccgatccatgctcagacaggat
gtgagctggtttgatgaccctaaaaacaccactggagcattgactaccaggctcgccaat
gatgctgctcaagttaaaggggctataggttccaggcttgctgtaattacccagaatata
gcaaatcttgggacaggaataattatatccttaatctatggttggcaactgacactgtta
ctcttagcaattgtacccatcattgcaatagcaggagttgttgaaatgaaaatgttgtct
ggacaagcactgaaagataagaaagaactagaaggtgctgggaagatcgctactgaagca
atagaaaacttccgaactgttgtttctttgactcaggagcagaagtttgaacatatgtat
gatcagagtttgcaggtaccatacagaaactctttgaggaaagcacacatctttggaatc
acgttttccttcacccaggcaatgatgtatttttcctatgctggatgtttccggtttgga
gcctacttggtggcacatagtctcatgagctttgaggatgttctcttagtattttcagct
gttgtctttggtgccatggccgtggggcaagtcagttcatttgctcctgactatgccaaa
gccaaagtatcagcagcccacatcatcatgatcattgaaaaaacccctttgattgacagc
tacagcacagaaggcctaaagccgaacacattggaaggaaatgtcacatttaatgaagtt
gtattcaactatcccacccgactggacatcccagtgcttcaggggctgagcctggaagtg
aagaagggccagacgctggccctggtgggcagcagtggctgtgggaagagcacggtggtc
cagctcctggagcggttctatgaccccttggcggggaaagtgctgcttgacggcaaagaa
ataaagcaactgaatgttcagtggctccgagcacacctgggcatcgtgtcccaggagccc
atcctgtttgactgcagcattagtgagaacattgcctatggagacaacagccgggtggtg
tcacaggaagagatcgtgagggcagccaaggaggccaatatacacgccttcatcgagtca
ctgcctaataaatatagcaccagagtaggagataaaggaactcagctctctggtggccag
aaacaacgcattgccatagctcgtgcccttgttagacagcctcatattttgcttttggat
gaagccacatcagctctggatacagaaagtgaaaaggttgtccaagaagccctggacaaa
gccagagaaggccgtacctgcattgtgattgctcaccgcctgtccaccatccagaatgca
gacttaatagtggtgtttcagaatggcagagtcaaggagcacggcacacatcagcagctg
ctggcacagaaaggcatctatttttcaatggtcagtgtccaggctggagcaaagcgccag
tga

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