Macaca nemestrina (pig-tailed macaque): 105475871
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Entry
105475871 CDS
T08765
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
mni
Macaca nemestrina (pig-tailed macaque)
Pathway
mni04217
Necroptosis
mni04380
Osteoclast differentiation
mni04620
Toll-like receptor signaling pathway
mni04621
NOD-like receptor signaling pathway
mni04630
JAK-STAT signaling pathway
mni04658
Th1 and Th2 cell differentiation
mni04659
Th17 cell differentiation
mni05145
Toxoplasmosis
mni05160
Hepatitis C
mni05161
Hepatitis B
mni05162
Measles
mni05164
Influenza A
mni05165
Human papillomavirus infection
mni05167
Kaposi sarcoma-associated herpesvirus infection
mni05168
Herpes simplex virus 1 infection
mni05169
Epstein-Barr virus infection
mni05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
mni00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
105475871 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
105475871 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
105475871 (TYK2)
04621 NOD-like receptor signaling pathway
105475871 (TYK2)
04658 Th1 and Th2 cell differentiation
105475871 (TYK2)
04659 Th17 cell differentiation
105475871 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
105475871 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
105475871 (TYK2)
05160 Hepatitis C
105475871 (TYK2)
05171 Coronavirus disease - COVID-19
105475871 (TYK2)
05164 Influenza A
105475871 (TYK2)
05162 Measles
105475871 (TYK2)
05168 Herpes simplex virus 1 infection
105475871 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
105475871 (TYK2)
05169 Epstein-Barr virus infection
105475871 (TYK2)
05165 Human papillomavirus infection
105475871 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
105475871 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mni01001
]
105475871 (TYK2)
Enzymes [BR:
mni01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
105475871 (TYK2)
Protein kinases [BR:
mni01001
]
Non-receptor tyrosine kinases
JAK family [OT]
105475871 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
RIO1
ABC1
Motif
Other DBs
NCBI-GeneID:
105475871
NCBI-ProteinID:
XP_011729750
Ensembl:
ENSMNEG00000038855
LinkDB
All DBs
Position
Unknown
AA seq
1193 aa
AA seq
DB search
MPLRHRGTTRGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHI
AHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRMRFYFRNWHGMNPQEL
AVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSSEEEIHHFK
NESLGMAFLHLCHLALCRGVPLEEVAKKTSFKDCIPLSFRRQIRQHSALTRLRLRNVFRR
FLQDFQPDRLSQQMVMVKYLATLERLAPRFGTERVPVCHLKLLAQAEGEPCYIRDSGEAP
TDPGPESAARPPTHEVLVTGTGGIQWWPVQEEVNKEEVSKGSSGGSGRNPQASLSGKKAK
AHKAIGQPADRLREPLWAYFCDFRDITHVVLKECCVSIHRQDNKCLELSLPSRAAALSFV
SLVDGYFRLTADSSHYLCHEVAPPRLVMSIQDGIHGPLLEPFVQAKLRPEDGLYLIQWST
SHPYRLILTVAQRSQAPDGTQSLRLRKFPIEQQAGAFVLEGWGRSFPSVRELGAALQGCL
LRAGDDCFSLRRRCLPQPGETSNLIIMRGARASSRTLNLSQLSFHRVDQKEITQLSHLGQ
GTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYE
TASLMSQVSHVHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQ
LASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP
WMAPECLPGGPNSLSIAMDKWGFGATLLEICFDGEAPLQSRSSSEKEHFYQRQHRLPEPS
CPELATLTSQCLTYEPTQRPSFRTILRDLTRLQPHTLPDLADVLIVNPDSSASDPTVFHK
RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIEILRTL
YHEHIVKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYL
HAQHYIHRDLAARNVLLDNDKLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK
EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGITQGQMTVLRLTELLERGERL
PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC
NT seq
3582 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgcgccatcgggggacaaccaggggcagcaagcccgttggggatggagcccag
cccatggctgccatgggaggcctgaaggtgcttctgcactgggctggtccaggcggtgga
gagccctgggtcactttcagtgagtcatcgctgacagctgaggaagtctgcatccacatt
gcacataaagtcggtatcactcctccttgtttcaatctcttcgccctcttcgatgctcag
gcccaagtctggttgcccccaaaccacatcctagagatccccagagatgcaagcctgatg
ctgtatttccgcatgaggttttatttccggaactggcatggcatgaatcctcaggagctg
gctgtgtaccgttgtggccccccaggaaccgaggcatcctcagatcagacagcacagggg
atgcaactcctggacccagcctcatttgagtacctctttgagcagggcaagcatgagttt
gtgaatgacgtggcatcactgtgggagctatcgagcgaggaggagatccaccactttaag
aatgagagcctgggcatggcctttctgcacctctgtcacctcgctctctgccgtggtgtc
cccctggaggaggtggccaagaagaccagcttcaaggactgtatcccgctctccttccgt
cggcagatccggcagcacagcgccctgacccggctgcgccttcggaacgtcttccgcagg
ttcctgcaggacttccagccggacagactctcccagcagatggtcatggtcaaatacctg
gccacactcgaacggctggcaccccgctttggcacagagcgtgtgcccgtgtgccacctg
aagctgctggcccaggcagagggagagccctgctacatccgggacagtggggaggcccct
acagaccctggccctgagtctgctgctagacccccaacccatgaggtgctggtgacaggc
actggtggcatccagtggtggccagtacaggaggaggtgaacaaggaggaggtgagcaag
ggttctagtggcggcagcggcaggaacccccaagccagcctgtctgggaagaaggccaag
gctcacaaggcaattggccagccggcggacaggctgcgggagccactgtgggcctacttc
tgcgacttccgggacatcacccacgtggtgctgaaagagtgctgtgtcagcatccaccgg
caggacaacaagtgcctggagctgagcctgccttcccgggctgcagcgctgtccttcgtg
tcgctggtggacggctatttccgcctgacggccgactccagccactacctgtgccatgag
gtggctcccccacggctggtgatgagcatccaggatgggatccatggacccctgctggag
ccgtttgtgcaggccaagctgcggcccgaggacggcctgtacctcattcagtggagcacc
agccacccctaccgcctgatcctcacagtggcccagcgtagccaggcaccagacggcaca
cagagcttgcggctccggaagttccccattgagcagcaagccggggcctttgtgctggag
ggctggggccggtccttccccagcgttcgggaacttggggccgccttgcagggctgcttg
ctgagggccggggacgactgcttctctctgcgtcgccgttgcctgccccaaccaggagaa
acctccaacctcatcatcatgcggggggctcgggccagcagcaggacactcaacctcagc
cagctcagcttccaccgggttgaccagaaggagatcacccagctgtcccacttgggccag
ggcacaaggaccaacgtgtacgagggccgcctgcgagtggagggcagtggggaccctgag
gagggcaagatggacgacgaggaccccctcgtgcctggaagggaccgtgggcaggagcta
cgagtggtgctcaaagtgctggacccgagtcaccatgacatcgccctggccttctatgag
acagccagcctcatgagccaggtctcccacgtgcacctggccttcgtgcacggcgtctgt
gtgcgcggccctgaaaatatcatggtgacagagtacgtggagcacggacccctggacgtg
tggctgcggagggagcggggccatgtgcccatggcttggaagatggtggtggcccagcag
ctagccagcgccctcagctacctggagaacaagaacctggtacatggtaatgtgtgtggc
cggaacatcctgctggctcggctggggctggcagagggcacgagccccttcatcaagctg
agtgatcccggcgtgggcctcggcgccctctccagggaggagcgggtggagcggatcccc
tggatggcccccgaatgcctcccaggtgggcccaacagcctaagcattgccatggacaag
tgggggtttggtgccaccctcctggagatctgctttgatggagaggccccgctgcagagc
cgcagctcctccgagaaggagcatttctaccagaggcagcaccggctgcccgagccctcc
tgcccagagctggccacactcaccagccagtgtctgacctatgagccaacccagaggcct
tcattccgcaccatcctgcgtgacctcacccggctgcagccccacactcttccagatctt
gctgatgtcttgattgtgaacccggactcatcggcgtcagaccctacggttttccacaag
cgctatttgaaaaagatccgagatctgggcgagggtcacttcggcaaggtcagtttgtac
tgctacgatccgaccaacgacggcactggcgagatggtggcggtgaaagcccttaaggca
gactgcggcccccagcaccgctcgggctggaagcaggagattgagattctgcgcacgctc
tatcacgagcacatcgtcaagtacaagggctgctgcgaggaccaaggcgagaagtcgctg
cagctggtcatggagtacgtgcccctgggcagcctccgagactacctgccccggcacagc
gtcgggctggcccagctgctgctcttcgcccagcagatctgcgagggcatggcctatctg
cacgcgcagcactacatccaccgagacctagccgcgcgcaacgtgctgctggacaacgac
aagctggtcaagatcggggactttggcctagctaaggccgtgcccgaaggccacgagtac
taccgcgtgcgcgaggatggggacagccccgtgttctggtatgccccagagtgcctgaaa
gagtataagttctactatgcgtccgatgtctggtccttcggggtgaccctgtatgagctg
ctgacgcactgtgactccagccagagcccccccacgaaattccttgagctcataggcatc
acccagggtcagatgacagttctgagactcaccgagttgctggaacgaggggagaggctg
ccacgacctgacaaatgtccctgtgaggtctatcatctcatgaagaactgctgggagaca
gaggcgtccttccgcccaaccttcgagaacctcatacccatcctgaagacagtccatgag
aagtaccaaggccaggccccttccgtgttcagtgtgtgctga
DBGET
integrated database retrieval system
