KEGG   Macaca nemestrina (pig-tailed macaque): 105480656
Entry
105480656         CDS       T08765                                 
Symbol
MAPK1
Name
(RefSeq) LOW QUALITY PROTEIN: mitogen-activated protein kinase 1
  KO
K04371  mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
Organism
mni  Macaca nemestrina (pig-tailed macaque)
Pathway
mni01521  EGFR tyrosine kinase inhibitor resistance
mni01522  Endocrine resistance
mni01524  Platinum drug resistance
mni04010  MAPK signaling pathway
mni04012  ErbB signaling pathway
mni04014  Ras signaling pathway
mni04015  Rap1 signaling pathway
mni04022  cGMP-PKG signaling pathway
mni04024  cAMP signaling pathway
mni04062  Chemokine signaling pathway
mni04066  HIF-1 signaling pathway
mni04068  FoxO signaling pathway
mni04071  Sphingolipid signaling pathway
mni04072  Phospholipase D signaling pathway
mni04114  Oocyte meiosis
mni04140  Autophagy - animal
mni04148  Efferocytosis
mni04150  mTOR signaling pathway
mni04151  PI3K-Akt signaling pathway
mni04210  Apoptosis
mni04218  Cellular senescence
mni04261  Adrenergic signaling in cardiomyocytes
mni04270  Vascular smooth muscle contraction
mni04350  TGF-beta signaling pathway
mni04360  Axon guidance
mni04370  VEGF signaling pathway
mni04371  Apelin signaling pathway
mni04380  Osteoclast differentiation
mni04510  Focal adhesion
mni04517  IgSF CAM signaling
mni04520  Adherens junction
mni04540  Gap junction
mni04550  Signaling pathways regulating pluripotency of stem cells
mni04611  Platelet activation
mni04613  Neutrophil extracellular trap formation
mni04620  Toll-like receptor signaling pathway
mni04621  NOD-like receptor signaling pathway
mni04625  C-type lectin receptor signaling pathway
mni04650  Natural killer cell mediated cytotoxicity
mni04657  IL-17 signaling pathway
mni04658  Th1 and Th2 cell differentiation
mni04659  Th17 cell differentiation
mni04660  T cell receptor signaling pathway
mni04662  B cell receptor signaling pathway
mni04664  Fc epsilon RI signaling pathway
mni04666  Fc gamma R-mediated phagocytosis
mni04668  TNF signaling pathway
mni04713  Circadian entrainment
mni04720  Long-term potentiation
mni04722  Neurotrophin signaling pathway
mni04723  Retrograde endocannabinoid signaling
mni04724  Glutamatergic synapse
mni04725  Cholinergic synapse
mni04726  Serotonergic synapse
mni04730  Long-term depression
mni04810  Regulation of actin cytoskeleton
mni04910  Insulin signaling pathway
mni04912  GnRH signaling pathway
mni04914  Progesterone-mediated oocyte maturation
mni04915  Estrogen signaling pathway
mni04916  Melanogenesis
mni04917  Prolactin signaling pathway
mni04919  Thyroid hormone signaling pathway
mni04921  Oxytocin signaling pathway
mni04926  Relaxin signaling pathway
mni04928  Parathyroid hormone synthesis, secretion and action
mni04929  GnRH secretion
mni04930  Type II diabetes mellitus
mni04933  AGE-RAGE signaling pathway in diabetic complications
mni04934  Cushing syndrome
mni04935  Growth hormone synthesis, secretion and action
mni04960  Aldosterone-regulated sodium reabsorption
mni05010  Alzheimer disease
mni05020  Prion disease
mni05022  Pathways of neurodegeneration - multiple diseases
mni05034  Alcoholism
mni05132  Salmonella infection
mni05133  Pertussis
mni05135  Yersinia infection
mni05140  Leishmaniasis
mni05142  Chagas disease
mni05145  Toxoplasmosis
mni05152  Tuberculosis
mni05160  Hepatitis C
mni05161  Hepatitis B
mni05163  Human cytomegalovirus infection
mni05164  Influenza A
mni05165  Human papillomavirus infection
mni05166  Human T-cell leukemia virus 1 infection
mni05167  Kaposi sarcoma-associated herpesvirus infection
mni05170  Human immunodeficiency virus 1 infection
mni05171  Coronavirus disease - COVID-19
mni05200  Pathways in cancer
mni05203  Viral carcinogenesis
mni05205  Proteoglycans in cancer
mni05206  MicroRNAs in cancer
mni05207  Chemical carcinogenesis - receptor activation
mni05208  Chemical carcinogenesis - reactive oxygen species
mni05210  Colorectal cancer
mni05211  Renal cell carcinoma
mni05212  Pancreatic cancer
mni05213  Endometrial cancer
mni05214  Glioma
mni05215  Prostate cancer
mni05216  Thyroid cancer
mni05218  Melanoma
mni05219  Bladder cancer
mni05220  Chronic myeloid leukemia
mni05221  Acute myeloid leukemia
mni05223  Non-small cell lung cancer
mni05224  Breast cancer
mni05225  Hepatocellular carcinoma
mni05226  Gastric cancer
mni05230  Central carbon metabolism in cancer
mni05231  Choline metabolism in cancer
mni05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mni05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mni00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105480656 (MAPK1)
   04012 ErbB signaling pathway
    105480656 (MAPK1)
   04014 Ras signaling pathway
    105480656 (MAPK1)
   04015 Rap1 signaling pathway
    105480656 (MAPK1)
   04350 TGF-beta signaling pathway
    105480656 (MAPK1)
   04370 VEGF signaling pathway
    105480656 (MAPK1)
   04371 Apelin signaling pathway
    105480656 (MAPK1)
   04668 TNF signaling pathway
    105480656 (MAPK1)
   04066 HIF-1 signaling pathway
    105480656 (MAPK1)
   04068 FoxO signaling pathway
    105480656 (MAPK1)
   04072 Phospholipase D signaling pathway
    105480656 (MAPK1)
   04071 Sphingolipid signaling pathway
    105480656 (MAPK1)
   04024 cAMP signaling pathway
    105480656 (MAPK1)
   04022 cGMP-PKG signaling pathway
    105480656 (MAPK1)
   04151 PI3K-Akt signaling pathway
    105480656 (MAPK1)
   04150 mTOR signaling pathway
    105480656 (MAPK1)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    105480656 (MAPK1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    105480656 (MAPK1)
   04148 Efferocytosis
    105480656 (MAPK1)
  09143 Cell growth and death
   04114 Oocyte meiosis
    105480656 (MAPK1)
   04210 Apoptosis
    105480656 (MAPK1)
   04218 Cellular senescence
    105480656 (MAPK1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105480656 (MAPK1)
   04520 Adherens junction
    105480656 (MAPK1)
   04540 Gap junction
    105480656 (MAPK1)
   04550 Signaling pathways regulating pluripotency of stem cells
    105480656 (MAPK1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    105480656 (MAPK1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    105480656 (MAPK1)
   04613 Neutrophil extracellular trap formation
    105480656 (MAPK1)
   04620 Toll-like receptor signaling pathway
    105480656 (MAPK1)
   04621 NOD-like receptor signaling pathway
    105480656 (MAPK1)
   04625 C-type lectin receptor signaling pathway
    105480656 (MAPK1)
   04650 Natural killer cell mediated cytotoxicity
    105480656 (MAPK1)
   04660 T cell receptor signaling pathway
    105480656 (MAPK1)
   04658 Th1 and Th2 cell differentiation
    105480656 (MAPK1)
   04659 Th17 cell differentiation
    105480656 (MAPK1)
   04657 IL-17 signaling pathway
    105480656 (MAPK1)
   04662 B cell receptor signaling pathway
    105480656 (MAPK1)
   04664 Fc epsilon RI signaling pathway
    105480656 (MAPK1)
   04666 Fc gamma R-mediated phagocytosis
    105480656 (MAPK1)
   04062 Chemokine signaling pathway
    105480656 (MAPK1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    105480656 (MAPK1)
   04929 GnRH secretion
    105480656 (MAPK1)
   04912 GnRH signaling pathway
    105480656 (MAPK1)
   04915 Estrogen signaling pathway
    105480656 (MAPK1)
   04914 Progesterone-mediated oocyte maturation
    105480656 (MAPK1)
   04917 Prolactin signaling pathway
    105480656 (MAPK1)
   04921 Oxytocin signaling pathway
    105480656 (MAPK1)
   04926 Relaxin signaling pathway
    105480656 (MAPK1)
   04935 Growth hormone synthesis, secretion and action
    105480656 (MAPK1)
   04919 Thyroid hormone signaling pathway
    105480656 (MAPK1)
   04928 Parathyroid hormone synthesis, secretion and action
    105480656 (MAPK1)
   04916 Melanogenesis
    105480656 (MAPK1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    105480656 (MAPK1)
   04270 Vascular smooth muscle contraction
    105480656 (MAPK1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    105480656 (MAPK1)
  09156 Nervous system
   04724 Glutamatergic synapse
    105480656 (MAPK1)
   04725 Cholinergic synapse
    105480656 (MAPK1)
   04726 Serotonergic synapse
    105480656 (MAPK1)
   04720 Long-term potentiation
    105480656 (MAPK1)
   04730 Long-term depression
    105480656 (MAPK1)
   04723 Retrograde endocannabinoid signaling
    105480656 (MAPK1)
   04722 Neurotrophin signaling pathway
    105480656 (MAPK1)
  09158 Development and regeneration
   04360 Axon guidance
    105480656 (MAPK1)
   04380 Osteoclast differentiation
    105480656 (MAPK1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    105480656 (MAPK1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105480656 (MAPK1)
   05206 MicroRNAs in cancer
    105480656 (MAPK1)
   05205 Proteoglycans in cancer
    105480656 (MAPK1)
   05207 Chemical carcinogenesis - receptor activation
    105480656 (MAPK1)
   05208 Chemical carcinogenesis - reactive oxygen species
    105480656 (MAPK1)
   05203 Viral carcinogenesis
    105480656 (MAPK1)
   05230 Central carbon metabolism in cancer
    105480656 (MAPK1)
   05231 Choline metabolism in cancer
    105480656 (MAPK1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105480656 (MAPK1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    105480656 (MAPK1)
   05212 Pancreatic cancer
    105480656 (MAPK1)
   05225 Hepatocellular carcinoma
    105480656 (MAPK1)
   05226 Gastric cancer
    105480656 (MAPK1)
   05214 Glioma
    105480656 (MAPK1)
   05216 Thyroid cancer
    105480656 (MAPK1)
   05221 Acute myeloid leukemia
    105480656 (MAPK1)
   05220 Chronic myeloid leukemia
    105480656 (MAPK1)
   05218 Melanoma
    105480656 (MAPK1)
   05211 Renal cell carcinoma
    105480656 (MAPK1)
   05219 Bladder cancer
    105480656 (MAPK1)
   05215 Prostate cancer
    105480656 (MAPK1)
   05213 Endometrial cancer
    105480656 (MAPK1)
   05224 Breast cancer
    105480656 (MAPK1)
   05223 Non-small cell lung cancer
    105480656 (MAPK1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105480656 (MAPK1)
   05170 Human immunodeficiency virus 1 infection
    105480656 (MAPK1)
   05161 Hepatitis B
    105480656 (MAPK1)
   05160 Hepatitis C
    105480656 (MAPK1)
   05171 Coronavirus disease - COVID-19
    105480656 (MAPK1)
   05164 Influenza A
    105480656 (MAPK1)
   05163 Human cytomegalovirus infection
    105480656 (MAPK1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105480656 (MAPK1)
   05165 Human papillomavirus infection
    105480656 (MAPK1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105480656 (MAPK1)
   05135 Yersinia infection
    105480656 (MAPK1)
   05133 Pertussis
    105480656 (MAPK1)
   05152 Tuberculosis
    105480656 (MAPK1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    105480656 (MAPK1)
   05140 Leishmaniasis
    105480656 (MAPK1)
   05142 Chagas disease
    105480656 (MAPK1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105480656 (MAPK1)
   05020 Prion disease
    105480656 (MAPK1)
   05022 Pathways of neurodegeneration - multiple diseases
    105480656 (MAPK1)
  09165 Substance dependence
   05034 Alcoholism
    105480656 (MAPK1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105480656 (MAPK1)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    105480656 (MAPK1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    105480656 (MAPK1)
   04934 Cushing syndrome
    105480656 (MAPK1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    105480656 (MAPK1)
   01524 Platinum drug resistance
    105480656 (MAPK1)
   01522 Endocrine resistance
    105480656 (MAPK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mni01001]
    105480656 (MAPK1)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mni03036]
    105480656 (MAPK1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mni04147]
    105480656 (MAPK1)
Enzymes [BR:mni01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     105480656 (MAPK1)
Protein kinases [BR:mni01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   105480656 (MAPK1)
Chromosome and associated proteins [BR:mni03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Protein kinases
     105480656 (MAPK1)
Exosome [BR:mni04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   105480656 (MAPK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH STATB_N Haspin_kinase FTA2 Kdo
Other DBs
NCBI-GeneID: 105480656
NCBI-ProteinID: XP_024648346
Ensembl: ENSMNEG00000030093
LinkDB
Position
Unknown
AA seq 360 aa
MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFE
HQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQH
LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDH
TGFLTEYGGVHVGTGSRIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI
LGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHK
RIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
NT seq 1083 nt   +upstreamnt  +downstreamnt
atggcggcggcggcggcggcgggcgcgggcccggagatggtccgcgggcaggtgttcgac
gtgggaccgcgctacaccaacctctcgtacatcggcgagggtgcctacggcatggtgtgc
tctgcttatgataatgtcaacaaagttcgagtagctatcaagaaaatcagcccctttgag
caccagacctactgccagagaaccctgcgggagataaaaatcttactgcgcttcagacat
gagaacatcattggaatcaatgacattattcgagcaccaaccatcgagcaaatgaaagat
gtatatatagtacaagacctcatggaaacagatctttacaagctcttgaagacacaacac
ctcagcaacgaccatatctgctattttctttaccagatcctcagagggttaaaatatatc
cattcagctaacgttctgcaccgtgacctcaagccttccaacctgctgctcaacaccacc
tgtgatctcaagatctgtgactttggcctggcccgtgttgcagatccagaccatgatcac
acagggttcctgacagaatatggtggcgtacacgttggtacaggctccagaattatgttg
aattccaagggctacaccaagtccattgatatttggtctgtaggctgcattctggcagaa
atgctttctaacaggcccatctttccagggaagcattatcttgaccagctgaaccacatt
ctgggtattcttggatccccgtcacaagaagacctgaattgtataataaatttaaaagct
aggaactatttgctttctcttccacacaaaaataaggtgccatggaacaggctgttccca
aatgctgactccaaagctctggacttactggacaaaatgttgacattcaaccctcacaag
aggattgaagtagaacaggctctggcccacccatatctggagcagtattacgacccgagt
gacgagcccattgccgaagcaccattcaaatttgacatggaattggatgacttgcctaag
gaaaagctcaaagaactaatttttgaagagactgctagattccagccgggatacagatct
taa

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