Macaca nemestrina (pig-tailed macaque): 105481847
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Entry
105481847 CDS
T08765
Symbol
SOS2
Name
(RefSeq) LOW QUALITY PROTEIN: son of sevenless homolog 2
KO
K03099
son of sevenless
Organism
mni
Macaca nemestrina (pig-tailed macaque)
Pathway
mni01521
EGFR tyrosine kinase inhibitor resistance
mni01522
Endocrine resistance
mni04010
MAPK signaling pathway
mni04012
ErbB signaling pathway
mni04014
Ras signaling pathway
mni04062
Chemokine signaling pathway
mni04068
FoxO signaling pathway
mni04072
Phospholipase D signaling pathway
mni04150
mTOR signaling pathway
mni04151
PI3K-Akt signaling pathway
mni04510
Focal adhesion
mni04540
Gap junction
mni04630
JAK-STAT signaling pathway
mni04650
Natural killer cell mediated cytotoxicity
mni04660
T cell receptor signaling pathway
mni04662
B cell receptor signaling pathway
mni04664
Fc epsilon RI signaling pathway
mni04714
Thermogenesis
mni04722
Neurotrophin signaling pathway
mni04810
Regulation of actin cytoskeleton
mni04910
Insulin signaling pathway
mni04912
GnRH signaling pathway
mni04915
Estrogen signaling pathway
mni04917
Prolactin signaling pathway
mni04926
Relaxin signaling pathway
mni04935
Growth hormone synthesis, secretion and action
mni05034
Alcoholism
mni05160
Hepatitis C
mni05161
Hepatitis B
mni05163
Human cytomegalovirus infection
mni05165
Human papillomavirus infection
mni05200
Pathways in cancer
mni05205
Proteoglycans in cancer
mni05206
MicroRNAs in cancer
mni05207
Chemical carcinogenesis - receptor activation
mni05208
Chemical carcinogenesis - reactive oxygen species
mni05210
Colorectal cancer
mni05211
Renal cell carcinoma
mni05213
Endometrial cancer
mni05214
Glioma
mni05215
Prostate cancer
mni05220
Chronic myeloid leukemia
mni05221
Acute myeloid leukemia
mni05223
Non-small cell lung cancer
mni05224
Breast cancer
mni05225
Hepatocellular carcinoma
mni05226
Gastric cancer
mni05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mni00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
105481847 (SOS2)
04012 ErbB signaling pathway
105481847 (SOS2)
04014 Ras signaling pathway
105481847 (SOS2)
04630 JAK-STAT signaling pathway
105481847 (SOS2)
04068 FoxO signaling pathway
105481847 (SOS2)
04072 Phospholipase D signaling pathway
105481847 (SOS2)
04151 PI3K-Akt signaling pathway
105481847 (SOS2)
04150 mTOR signaling pathway
105481847 (SOS2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
105481847 (SOS2)
04540 Gap junction
105481847 (SOS2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
105481847 (SOS2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
105481847 (SOS2)
04660 T cell receptor signaling pathway
105481847 (SOS2)
04662 B cell receptor signaling pathway
105481847 (SOS2)
04664 Fc epsilon RI signaling pathway
105481847 (SOS2)
04062 Chemokine signaling pathway
105481847 (SOS2)
09152 Endocrine system
04910 Insulin signaling pathway
105481847 (SOS2)
04912 GnRH signaling pathway
105481847 (SOS2)
04915 Estrogen signaling pathway
105481847 (SOS2)
04917 Prolactin signaling pathway
105481847 (SOS2)
04926 Relaxin signaling pathway
105481847 (SOS2)
04935 Growth hormone synthesis, secretion and action
105481847 (SOS2)
09156 Nervous system
04722 Neurotrophin signaling pathway
105481847 (SOS2)
09159 Environmental adaptation
04714 Thermogenesis
105481847 (SOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105481847 (SOS2)
05206 MicroRNAs in cancer
105481847 (SOS2)
05205 Proteoglycans in cancer
105481847 (SOS2)
05207 Chemical carcinogenesis - receptor activation
105481847 (SOS2)
05208 Chemical carcinogenesis - reactive oxygen species
105481847 (SOS2)
05231 Choline metabolism in cancer
105481847 (SOS2)
09162 Cancer: specific types
05210 Colorectal cancer
105481847 (SOS2)
05225 Hepatocellular carcinoma
105481847 (SOS2)
05226 Gastric cancer
105481847 (SOS2)
05214 Glioma
105481847 (SOS2)
05221 Acute myeloid leukemia
105481847 (SOS2)
05220 Chronic myeloid leukemia
105481847 (SOS2)
05211 Renal cell carcinoma
105481847 (SOS2)
05215 Prostate cancer
105481847 (SOS2)
05213 Endometrial cancer
105481847 (SOS2)
05224 Breast cancer
105481847 (SOS2)
05223 Non-small cell lung cancer
105481847 (SOS2)
09172 Infectious disease: viral
05161 Hepatitis B
105481847 (SOS2)
05160 Hepatitis C
105481847 (SOS2)
05163 Human cytomegalovirus infection
105481847 (SOS2)
05165 Human papillomavirus infection
105481847 (SOS2)
09165 Substance dependence
05034 Alcoholism
105481847 (SOS2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
105481847 (SOS2)
01522 Endocrine resistance
105481847 (SOS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
RHG20_PH
IQ_SEC7_PH
Motif
Other DBs
NCBI-GeneID:
105481847
NCBI-ProteinID:
XP_011739946
Ensembl:
ENSMNEG00000027545
UniProt:
A0A2K6B554
LinkDB
All DBs
Position
Unknown
AA seq
1227 aa
AA seq
DB search
MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPTLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPSDI
EKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPEFNEHFNKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEQEDRECLNQAITALMNLQGSMDRIYKQHSPRRRPGDPVCPFYSHQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHGQTRLPG
YSSAEYRLKEKFVMRKIQICDKEDTCECKHAFELVSKDENSVVFAAKSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTDADKLA
IEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPAIEWHISKPGQFETFDLMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAVLSRVIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKILD
EAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPDMRRFFENLNPMGNSSEKEFTDYLFNKSLEIEPRNCK
QPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTV
SAPTSPNTPSTPPVSASSDLSVFLDVDLSSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS
EEPLIPPPLPPRKKFDHDASNSKGNMKSDDDPPAIPPRQPPPPKVKPRVPVPTVHLMGLC
IVHLHHHQEILFLIPLHRFPFGLQNTL
NT seq
3684 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaggcgccgcagccttacgagttcttcagtgaggagaatagtccgaaatggcgg
ggactgttggtctcggccctgcggaaggttcaggaacaagtgcatcccactctctcagct
aatgaagagtctctctattatattgaagagctgatttttcagctgcttaataaattatgc
atggcccagccaaggactgttcaagatgtagaggagcgagttcagaagacctttcctcac
ccaattgataaatgggccattgctgatgcacaatctgctatagaaaaacgaaaaagaaga
aatcctcttttactgcctgtggacaaaatccatccttcgttgaaggaagtgttagggtac
aaagtggactaccatgtgtccctatatattgtggctgtactagaatatatctcagctgat
attttaaaattggctggtaattatgtttttaatatccggcattatgaaatatctcagcag
gacattaaagtgtcaatgtgtgcggataaggttttgatggacatgtttgatcaggatgat
ataggcttggtttctctctgtgaagatgaacctagttcttccggtgaattaaactactat
gatcttgtcagaactgaaattgcagaagaaagacagtatctacgggaattaaatatgatc
ataaaagtgtttcgagaagcctttctttctgatagaaagctgtttaaaccttctgatatt
gaaaagatttttagtaatatttcagatatacatgaattgactgtgaaacttttaggtttg
attgaagacacagttgaaatgactgatgaaagcagtcctcatcccttagctggcagctgt
tttgaagatttggcagaagagcaagcatttgatccttatgaaacattatcacaagacatt
ctttcaccagagtttaatgaacatttcaataaattgatggccagacctgcagttgctcta
cactttcagtctattgctgatggctttaaagaggcagttcgttatgtccttccacgtctt
atgctggtgccagtgtatcactgttggcactattttgagttactaaagcaattgaaagca
tgtagtgaagaacaagaagacagagaatgtttgaaccaagctattactgctctcatgaat
ctccaaggtagcatggaccgaatttacaagcagcattcacctagacgccgacctggagat
cctgtttgccctttttatagtcaccaattaagaagcaaacacctggctatcaaaaaaatg
aatgaaattcagaaaaatatcgatggatgggaaggcaaagatattggacagtgttgtaat
gaattcattatggagggaccattgacaagaatcggtgccaaacatgaacggcatattttt
ctgtttgatggcttaatgatcagttgtaaacctaatcatggccagactcggcttccaggt
tacagtagtgcagaatacaggttaaaagaaaaatttgtcatgaggaaaatacaaatttgt
gataaagaagatacttgtgagtgcaagcatgcttttgaattagtatccaaagatgagaac
agcgtagtatttgctgctaagtctgctgaagaaaaaaacaactggatggcagcccttatt
tctcttcattatcgtagtactctagatcgaatgttagattcagtattactgaaagaagaa
aatgagcaaccactgagattaccaagtcctgaagtatatcgttttgtagtaaaagactct
gaggaaaacattgtttttgaagacaacttgcaaagtagaagtggcatccccattattaaa
ggaggaactgtagtgaagttaattgaaaggttaacatatcatatgtatgcagatcccaat
tttgttcgtacttttcttaccacatatcgttcattttgtaaaccacaggaattgctgagc
ttactgattgaacggtttgaaatcccagagccagaacctactgacgcagacaaactggca
atagagaaaggcgagcagccaatcagtgcagaccttaaaagatttcgcaaggaatacgtc
caaccagtacaacttaggatcttaaatgtatttcggcattgggttgaacatcatttttat
gactttgaaagagatttggaattgcttgaaagactagaatccttcatttcaagtgtaaga
gggaaagctatgaagaaatgggtagagtcaatcgctaagatcatcaagaggaagaagcaa
gctcaggcaaacggaataagccataatattacctttgaaagtccacctccagcaattgaa
tggcatatcagcaaaccaggacagtttgaaacatttgatctcatgacacttcatccaata
gaaattgcacgtcagctgacacttttggagtctgatctctacaggaaagttcaaccatct
gaacttgtaggaagtgtgtggaccaaagaagataaagaaataaattctccaaatttatta
aaaatgattcgccataccacaaatctcaccctctggtttgaaaaatgcattgtggaagca
gaaaattttgaagaacgggttgcagtactaagtagagttatagaaattctgcaagttttt
caagatttgaataatttcaatggcgtattggagatagtcagtgcagtaaattcagtgtca
gtatacagactagaccatacctttgaggcactgcaggaaagaaaaaggaaaattttggat
gaagctgtggaattaagtcaagatcactttaaaaaatacctagtaaaacttaagtcaatc
aatccaccttgtgtgcctttttttggaatatatttaacaaatattctgaagactgaagaa
gggaacaatgattttttaaaaaagaaagggaaagatttaatcaatttcagtaagaggagg
aaagtagctgaaattactggagaaattcagcagtatcagaatcagccttactgtttacgg
atagaaccagatatgaggagattctttgaaaaccttaaccccatgggaaattcgtctgaa
aaagagtttacagattatttgttcaacaagtcactagaaattgaacctcgaaactgcaaa
cagccacctcgatttcctagaaaatcaactttctccttgaaatctcctggaataaggcct
aacacaggccgacatggctctacctcaggtactttacgaggtcacccaacaccattagaa
agagaaccatgtaaaataagctttagtcggattgctgaaactgagctggaatcaacagtg
tcagcaccaacttctccaaatacaccatctactccaccagtatctgcttcttcagacctt
agtgtatttttagatgtggatctcagcagctcctgtggcagcaatagcatctttgctcca
gtgcttttgccacattcaaagtctttctttagttcatgtggtagtttacataaactaagt
gaagagcccctgattcctcctcctcttcctcctcgaaaaaagtttgatcatgatgcttca
aattctaagggaaatatgaaatctgatgatgatcctcctgctattccaccgagacagcct
cctcctcccaaggtaaaacccagagttcctgttcctactgtgcatttgatgggcctctgc
atagtccacctccaccaccaccaagagatcctcttcctgatacccctccaccggttcccc
ttcggcctccagaacactttataa
DBGET
integrated database retrieval system
