Macaca nemestrina (pig-tailed macaque): 105485816 Help Entry 105485816         CDS       T08765                                  Symbol TSC2 Name (RefSeq) tuberin isoform X13   KO K07207   tuberous sclerosis 2 Organism mni  Macaca nemestrina (pig-tailed macaque) Pathway mni04072   Phospholipase D signaling pathway mni04115   p53 signaling pathway mni04140   Autophagy - animal mni04150   mTOR signaling pathway mni04151   PI3K-Akt signaling pathway mni04152   AMPK signaling pathway mni04211   Longevity regulating pathway mni04218   Cellular senescence mni04714   Thermogenesis mni04910   Insulin signaling pathway mni04919   Thyroid hormone signaling pathway mni05163   Human cytomegalovirus infection mni05165   Human papillomavirus infection mni05168   Herpes simplex virus 1 infection mni05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:mni00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     105485816 (TSC2)    04151 PI3K-Akt signaling pathway     105485816 (TSC2)    04152 AMPK signaling pathway     105485816 (TSC2)    04150 mTOR signaling pathway     105485816 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     105485816 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     105485816 (TSC2)    04218 Cellular senescence     105485816 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     105485816 (TSC2)    04919 Thyroid hormone signaling pathway     105485816 (TSC2)   09149 Aging    04211 Longevity regulating pathway     105485816 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     105485816 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     105485816 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     105485816 (TSC2)    05163 Human cytomegalovirus infection     105485816 (TSC2)    05165 Human papillomavirus infection     105485816 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:mni01009]     105485816 (TSC2) Protein phosphatases and associated proteins [BR:mni01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      105485816 (TSC2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Cnd1 Motif Other DBs NCBI-GeneID:  105485816 NCBI-ProteinID:  XP_011746622 Ensembl:  ENSMNEG00000044090 LinkDB All DBs Position Unknown AA seq 1821 aa AA seqDB search MAKPTSKDSGLKEKFRILFGLGTPRPNPRSAEGKQTEFIITAEILRELSVECGLSNRIRM IGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIIQGQGERLGVLR ALFFKVIKDYPSNEDLHERLDVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVL VNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFI VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVG MALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVTWDI LLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPE SSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFY EEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLS PPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKH SYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKAS GPLSPPTGPPGPAPAGPAVRLGSLPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYK VLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTELHLAVVPVLTALISYHNYL DKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIMIKALPVLVVKLTHISATASMA VPLLEFLSTLARLPQLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC RLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNS PPVKEFKESSAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSVAQADDSLKSLHL ELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSL LGLDSGELQSGPESSSSPGMNVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVG ALDVPASQFPGSAASPGPQTAPAAKPEKASAGTRLPVQEKTNLAAYVPLLTQGWAEILVR RPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAAST AKPPPLPRSNTVASFSSLYQSSCQGQLHRSVSWADSAVVMEEGSPGEVPVPVEPPGLEDF EAALGVDRRTDAYSRSSSTSSQEEKSFHAEELVAGGIPIERAVSSEGGRPSVDLSFQPSQ PLSKSSSSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGILDGESAAWPASGEDSRGQ PEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGRRVERDAFKSRATASNAEKVPGINPSFV FLQLYHSPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELA ILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFH IATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIITPLDYEC NLVSLQCRKGGARVGPVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVH HSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHTKGPAQTPAEPTP GYEMGQRKRLISSVEDFTEFV NT seq 5466 nt NT seq  +upstreamnt  +downstreamnt atggccaaaccaacaagcaaagattcaggcttgaaggagaagtttaggattctgtttgga ctgggaacaccgaggccaaatcccaggtctgcagagggcaaacagacggaatttatcatc accgccgaaatcctgagagagctgagtgtggaatgcggcctcagcaatcgcatccggatg atagggcagatttgtgaagtcgcaaaaaccaagaaatttgaagagcacgcagtggaagca ctctggaaggcggttgcggatctgttgcagccagaacggccgctggaggcccggcacgcg gtgctggctctgctgaaggccatcattcaggggcagggcgagcgtttgggggtcctcagg gccctcttctttaaggtcatcaaggattacccttccaacgaagacctccacgagaggctg gacgttttcaaggccctcacagacaatgggagacacatcacctacttggaggaagagctg gcggactttgtcctgcagtggatggatgtcggcttgtcctcggaattccttctggtgctg gtgaacttggtcaaattcaacagctgttacctcgatgagtacatcgcaaggatggttcag atgatctgcctgctctgcgtccggaccgcatcctctgtggacatagaggtctccctgcag gtgctggacgccgtggtctgctacaactgcctgccggctgagagcctcccgctgttcatc gtcaccctgtgccgcaccatcaatgtcaaggagctctgcgagccttgctggaagctgatg cggaacctccttggcacccacctgggccacagtgccatctacaacatgtgccacctcatg gaggacagagcctacatggaggacgcgcccctgctgagaggagccgtgttttttgtgggc atggctctctggggagcccaccggctctattctctcaggaactcgccgacatcggtgctg ccatcattttaccaggccatggcatgtccgaacgaggtggtgtcctatgagatcgtcctg tccatcaccaggctcatcaagaagtataggaaggagctccaggtggtgacgtgggacatt ctgctgaacatcatcgaacggctccttcagcagctccagaccttggacagcccggagctc aggaccatcgtccatgacctgctgaccacggtggaggagctgtgtgaccagaatgagttc cacgggtctcaggagagatactttgaactggtggagagatgtgcagaccagaggcctgag tcctccctcctgaacctgatctcctacagagcacagtccattcacccggccaaggacggc tggattcagaacctgcaggcgctgatggagagattcttcaggagcgagtcccgaggcgcc gtgcgcatcaaggtgctggatgtgctgtcctttgtgctgctcatcaacaggcagttctac gaggaggagctgattaactcagtggtcatctctcagctctcccacatccccgaggataaa gaccatcaggtccgaaagctggccacccagttgctggtggacctggcagagggctgccac acacaccacttcaacagtctgctggacatcatcgagaaggtgatggcccgctccctctcc ccacccccggagttggaagaaagggatgtggccgcgtactcggcgtccttggaggatgtg aagacagctgtcctggggcttctggtcatccttcagactaagctgtacaccctgcctgcg agccatgccacgcgcgtttatgagatgctggtcagccacattcagctccactacaagcac agctacaccctgccaatcgccagcagcatccggctgcaggcctttgacttcctgttgctg ctgcgggccgactcactgcaccgcctcggcctgcccaacaaggatggggtcgtgcggttc agcccctactgcgtctgcgactacatggagccggagagaggctctgagaagaaggccagc ggccccctttctcctcccacagggccacctggcccggcgcctgcaggcccggctgtgcgg ctgggctccctgccctactccctgctcttccgcgtcctgctgcagtgcttgaagcaggag tctgactggaaggtgctgaagctggttctgggcaggctgcctgagtccctgcgctacaaa gtactcatctttacctccccttgcagtgtggaccagctgtgctctgctctctgctccatg ctttcaggcccaaagacactggagcggctccgaggcgccccggaaggcttctccagaact gagctgcacctggctgtggttccagtgctgacagcattaatctcttaccataactacctg gacaaaaccaaacagcgcgagatggtctactgcctggagcagggcctcatccaccgctgt gccagccagtgcgtcgtagccttgtccatctgcagcgtggagatgcctgacatcatgatc aaggcgctgcccgtcctggtggtgaagctcacacacatctcggccacagccagcatggcc gtcccgctgctggagttcctgtccactctggccaggctgccgcagctctacaggaacttc gccgcggagcagtatgccagtgtgttcgccatctcactgccgtacaccaacccctccaag tttaatcagtacatcgtgtgtctggcccatcacgtcatagccatgtggtttatcaggtgc cgcctgcccttccggaaggattttgtccctttcatcactaagggcctgcggtccaatgtt ctcttgtcttttgatgacacccccgagaaggacagcttcagggcccggagtactagtctc aacgagaggcccaagagtctgaggatagccagaccccccaaacaaggcttgaataactct ccacccgtgaaagaattcaaggagagctctgcagccgaggccttccggtgccgcagcatc agtgtgtctgaacatgtggtccgcagcaggatacagacgtccctcaccagtgccagcctg gggtctgcagacgagaactccgtggcccaggctgacgatagcctgaaaagcctccatctg gagctcacggaaacctgtctggacatgatggcccgatacgtcttctccaacttcacagct gtcccgaagaggtctcctgtgggcgagttcctcctggcgggtggcaggaccaaaacctgg ctggttgggaacaagcttgtcactgtgacgacgagtgtgggaaccgggacccggtcgtta ctaggcctggactcgggggagctgcagtccggcccggagtcgagctccagccccggcatg aatgtgagacagacgaaggaggcgccagccaagctggagtcccaggctgggcagcaggtg tcccgtggggcccgggaccgggtccgttctatgtcagggggccatggtcttcgagttggc gccctggatgtgccggcctcccagttcccgggcagtgccgcttctccaggaccacagact gcaccagccgcgaagcctgagaaggcctcggccggcacccggcttcctgtgcaggagaag acgaacctggccgcctacgtgcccctgctgacccagggctgggcggagatcctggtccgg aggcccacagggaacaccagctggctgatgagcctggagaacccgctcagccctttctcc tcggacatcaacaacatgcccctgcaggagctgtccaacgccctcatggcagctgagcgc ttcaaggagcaccgggacacagccctgtacaagtcgctgtcggtgccagcggccagcacg gccaaaccccctcctctgcctcgctccaacacagtggcctctttctcctccctgtaccag tccagctgccaaggacagctgcacaggagcgtttcctgggcagactccgccgtggtcatg gaggagggaagtcctggcgaggttcctgtgccagtggagcccccaggattggaggacttt gaggcggcgctaggcgtggacaggcgcacagacgcctacagcaggtcgtcctcaacctcc agccaggaggagaagtcattccacgcagaggagctggttgccgggggaatccccattgaa cgagccgtctcctcggagggtggccggccctctgtggacctctccttccagccctcacag cccctgagcaagtctagctcctctcctgagctgcagaccctgcaggacatcctcggggac cctggggacaaggctgacgtgggccggctgagccctgaggttaaggcccgttcacagtca gggatcctggacggggaaagtgctgcctggccagcctcgggcgaagacagtcggggccag cccgagggtcccttgccttccagctccccccgctcacccagtggcctccggccccgcggt tacaccatctccgactcggccccatcacgcaggggcaggagggtagaaagggatgccttt aagagcagagccacagcttccaatgcagagaaagtgccaggcatcaaccccagtttcgtg ttcctgcagctctaccattcgcctttctttggcgacgagtcaaacaagccaatcctgctg cccaatgagtcacagtcctttgagcggtcggtgcagctcctcgaccagatcccatcatac gacacccacaagatcgccgtcctgtatgtgggagaaggccagagcaacagtgagctcgcc atcctgtccaatgagcatggctcctacaggtacacggagttcctgacgggcctgggccgg ctcatcgagctcaaggactgccagccagacaaggtgtacctgggcggcctggacgtgtgt ggtgaggacggccagttcacctactgctggcacgacgacatcatgcaagccgtcttccac atcgccaccctgatgcccaccaaggacgtggacaagcatcgttgcgacaagaagcgccac ctgggcaacgatttcgtgtccattgtctacaatgactctggcgaggacttcaagctcggc accatcaagggccagttcaactttgtccacgtgatcatcaccccgctggactatgagtgc aacctggtgtccctgcagtgcaggaaaggtggggccagggtggggccggtgtccctgcag tgcaggaaagacatggagggccttgtggacaccagcgtggccaagatcgtgtctgaccgc aacctgccttttgtggcccgtcagatggccctgcatgcaaacatggcctcacaggtgcac cacagccgctccaaccccaccgatatctacccctccaagtggattgcccggctccgccac atcaagagactccgccagcggatctgcgaggaagccgcctactccaaccccagcctgcct ctggtgcaccccccatcccataccaaagggcctgcacagactccagccgagcccacgccc ggctacgagatgggccagcggaagcgcctcatctcctctgtggaggacttcaccgagttc gtgtga

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