KEGG   Macaca nemestrina (pig-tailed macaque): 105487544
Entry
105487544         CDS       T08765                                 
Symbol
PDE10A
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1
  KO
K18438  cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35]
Organism
mni  Macaca nemestrina (pig-tailed macaque)
Pathway
mni00230  Purine metabolism
mni01100  Metabolic pathways
mni04024  cAMP signaling pathway
mni05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:mni00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    105487544 (PDE10A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    105487544 (PDE10A)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    105487544 (PDE10A)
Enzymes [BR:mni01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.17  3',5'-cyclic-nucleotide phosphodiesterase
     105487544 (PDE10A)
    3.1.4.35  3',5'-cyclic-GMP phosphodiesterase
     105487544 (PDE10A)
SSDB
Motif
Pfam: PDEase_I GAF GAF_2 GAF_3 SpoVT_C HD DUF7334
Other DBs
NCBI-GeneID: 105487544
NCBI-ProteinID: XP_011749301
Ensembl: ENSMNEG00000027445
LinkDB
Position
Unknown
AA seq 847 aa
MSKKRKALEGGGGGGEPQLPEEEPTAWFGDSSEEQASRLPFMLKGGSKGPALLALRSGTD
PRAQMSDDTAEGTLDPCSAPGLTDEKVKAYLSLHPQVLDEFVSESVSAETVEKWLKRKNN
KSEDESAPKEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNQLLLYELSSIIKIATKADGF
ALYFLGECNNSLCIFTPPGIKEGKPRLIPAGPITQGTTISAYVAKSRKTLLVEDILGDER
FPRGTGLESGTRIQSVLCLPIVTAIGDLIGILELYRHWGKEAFCLSHQEVATANLAWASV
AIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQV
DHKNKELYSDLFDIGEEKEGKPVFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRF
NREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALAL
HCANMYHRIRHSECIYRVTMEKLSYHSICTAEEWQGLMRFTLPVRLCKEIELFHFDIGPF
ENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQ
NNHALFTDLERKGLLIACLCHDLDHRGFSNTYLQKFDHPLAALYSTSTMEQHHFSQTVSI
LQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHR
DRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEV
PQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLNQWEKVIRGEETATWISSPSVAQ
KAAASED
NT seq 2544 nt   +upstreamnt  +downstreamnt
atgtcgaagaaacgcaaagccctcgagggtggaggaggtggcggagaaccccagctccca
gaggaggaacccactgcctggtttggggacagcagcgaggagcaagccagccgcctcccc
ttcatgcttaaaggtgggagcaaaggacccgctttgttggctttgaggagcgggacagac
ccccgggcacagatgagcgatgacacagcagaaggcaccctggacccctgcagtgcgcca
ggtttgacagatgaaaaagtgaaggcatatctttctcttcacccccaggtattagatgaa
tttgtatctgaaagtgttagtgcagagacagtagagaaatggctgaagaggaagaacaac
aaatcagaagatgaatcggctcctaaggaagtcagcaggtaccaagatacgaatatgcag
ggagttgtatatgaactaaacagctatatagaacaacggttggacacaggaggagacaac
cagctactcctctatgaactgagcagcatcatcaaaatagccacaaaagctgatggattt
gcattgtatttccttggagagtgcaataatagcctgtgcatattcacaccacctgggata
aaggaaggaaaaccccgcctcatccctgctgggcccatcactcagggcaccaccatctct
gcttatgtggccaagtccaggaagacattgctagtagaagacatccttggagatgagcga
tttccaagaggtactggactggaatcagggactcgtatccagtctgttctttgcttacca
attgtcactgcaattggtgacttgattggtattcttgagctgtatcggcactggggcaaa
gaagccttctgtcttagtcaccaggaggttgcaacagcaaatcttgcctgggcttccgta
gcaatacatcaggtgcaggtatgcagaggccttgccaaacagactgaattgaatgacttt
ctactcgacgtatcaaaaacatactttgataacatagttgcaatagattctctacttgaa
cacataatgatatatgcaaaaaacctggtgaatgccgaccgttgtgcacttttccaggta
gaccataagaacaaggagttatattcagacctttttgatattggagaggaaaaggaagga
aaacccgtcttcaagaagaccaaagagataagattttcaattgagaaaggaattgctggc
caagtagcaagaacaggggaagtcctgaacattccagatgcctatgcagacccacgcttt
aacagagaagtagacttgtacacaggctacaccacgcggaacatcctgtgcatgcccatc
gtcagccgaggcagcgtgataggtgtggtgcagatggtcaacaaaatcagtggcagtgcc
ttctctaaaaccgatgaaaacaacttcaaaatgtttgccgtcttttgtgctttagcctta
cactgtgctaatatgtatcatagaattcgccactcagagtgcatttaccgggtaacaatg
gaaaagctgtcctaccatagcatttgtactgcagaagagtggcaaggcctcatgcgattt
acccttcctgtgcgtctctgcaaagaaattgaattattccactttgacattggtcctttt
gaaaacatgtggcctggaatttttgtctacatggttcatcggtcctgtgggacatcctgc
tttgagctcgaaaagttgtgtcgttttattatgtctgtgaagaagaactatcggcgggtt
ccttatcacaactggaagcatgcggtcactgtagcacactgcatgtacgccatacttcag
aacaaccacgcgcttttcacagaccttgagcgcaaaggactgctgatcgcgtgtctgtgt
catgacctagaccacagaggcttcagtaacacctacctgcagaagttcgaccaccctcta
gcagctctctactccacttccaccatggagcagcaccacttctcccagaccgtgtccatc
ctccagctggaagggcacaatatcttctccactctgagctccagtgaatacgagcaggtg
cttgagatcatccgcaaagccatcattgccacagaccttgctttatactttggaaacagg
aaacagttggaagagatgtaccagaccggatcgctaaaccttaataatcaatcacataga
gaccgtgtaattggtttgatgatgactgcctgtgacctttgttctgtgacaaaactgtgg
cccgttacaaaattgacggcaaatgatatatatgcagaattctgggctgagggtgatgaa
atgaagaaattgggaatacagcctattcctatgatggacagagacaagaaggatgaagtc
ccccaaggccagcttgggttctacaatgccgtagccattccctgctatacaacccttacc
cagatcctccctcccacggagcctctccttaaagcatgcagggataatctcaatcagtgg
gagaaggtgattcgaggggaggagactgcaacctggatttcatccccgtccgtggctcag
aaggcagctgcatctgaagattga

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