Macaca nemestrina (pig-tailed macaque): 105488936
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Entry
105488936 CDS
T08765
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
mni
Macaca nemestrina (pig-tailed macaque)
Pathway
mni01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
mni00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
105488936 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
mni03032
]
105488936 (TOP2B)
03036 Chromosome and associated proteins [BR:
mni03036
]
105488936 (TOP2B)
Enzymes [BR:
mni01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
105488936 (TOP2B)
DNA replication proteins [BR:
mni03032
]
Eukaryotic type
DNA Topoisomerases
105488936 (TOP2B)
Chromosome and associated proteins [BR:
mni03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
105488936 (TOP2B)
Centrosome formation proteins
Centriole proteins
105488936 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
105488936
NCBI-ProteinID:
XP_011751757
Ensembl:
ENSMNEG00000031938
UniProt:
A0A2K6BXX5
LinkDB
All DBs
Position
Unknown
AA seq
1626 aa
AA seq
DB search
MAKSGGCGAGAGVGGGNGALTWVTLFDQNNAAKKEESETANKNDSSKKLSVERVYQKKTQ
LEHILLRPDTYIGSVEPLTQFMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRD
KNMTCIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVT
GGRNGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITF
QPDLSKFKMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKL
DETGVALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIE
VVKKKNKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFF
KAASNCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLIL
TEGDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYK
KSYDDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVK
ASKNKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFR
YAGPEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFI
NKELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHH
GEQALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFP
AVDDNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRM
LDGLDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQV
LEPMLNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNS
MVLFDHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKI
QGKITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSG
PDFNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVE
AQEREDILAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRVIPEITAMKADASKKLLKK
KKGDLDTTAVKVEFDEEFSGVPVEGAGEEALIPSAPINKGPKPKREKKEPGTRVRKTPTS
SGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDD
DADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKK
SQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQIDKVPSKTVAAKKGKPS
SDTAPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTPPKGKGRGAKKRKASGSENEGDYNP
GRKTSKTASKKPKKTSFDQDSDVDIFPSDFPSEPPSLPRTGRARKEVKYFAESDEEEEDV
DFAMFN
NT seq
4881 nt
NT seq
+upstream
nt +downstream
nt
atggccaagtcgggtggctgcggcgcgggagccggcgtgggcggcggcaacggtgcactg
acctgggtgactctttttgatcagaacaatgctgcaaaaaaagaagagtcagaaactgcc
aacaaaaatgattcttcaaagaagttgtctgttgagagagtgtatcagaagaagacacaa
cttgaacacattcttcttcgtcctgatacatatattgggtcagtggagccattgacgcag
ttcatgtgggtgtatgatgaagatgtaggaatgaattgcagagaggttacctttgtgcca
ggtttatacaagatctttgatgaaattttggttaatgctgctgacaataaacagagggat
aagaacatgacttgtattaaagtttctattgatcctgaatctaacattataagcatttgg
aataatggaaaaggcattccagtagtagaacacaaggtagagaaagtttatgttcctgct
ttaatttttggacagcttttaacatccagtaactatgatgatgatgagaaaaaagttaca
ggtggtcgtaatggttatggtgcaaaactttgtaatattttcagtacaaagtttacagta
gaaacagcttgcaaagaatacaaacacagttttaagcagacatggatgaataatatgatg
aagacttctgaagccaaaattaaacattttgatggtgaagattacacatgcataacattc
caaccagatctgtccaaatttaagatggaaaaacttgacaaggatattgtggccctcatg
accagaagggcatatgatttggctggttcatgtaaaggggtcaaggtcatgtttaatgga
aagaaattgcctgtaaatggatttcgcagttatgtagatctttatgtgaaagacaaattg
gatgaaactggggtggccctcaaagttattcatgagcttgcaaatgaaagatgggatgtt
tgtctcacattgagtgaaaaaggattccagcagatcagctttgtaaatagtattgcgact
acaaaaggtggacggcacgtggattatgtggtagatcaagttgttggtaaactgattgaa
gtggttaagaaaaagaacaaagctggtgtatcagtgaaaccatttcaagtaaaaaaccat
atatgggtttttattaattgccttattgaaaatccaacttttgattctcagactaaggaa
aacatgactctgcagcccaaaagttttgggtctaaatgccagctgtcagaaaaatttttt
aaagcagcctctaattgtggcattgtagaaagtatcctaaactgggtgaaatttaaggct
cagactcagctgaataagaagtgttcatcagtaaaatacagtaaaatcaaaggtattccc
aaactggatgacgctaatgatgctggtggcaaacattccctggagtgtacactgatatta
acagagggagactctgccaaatcactggctgtgtctggattaggtgtgattggacgagac
agatacggagtttttccactcaggggcaaaattcttaacgtacgggaagcttctcataaa
cagatcatggaaaatgctgaaataaataatattattaaaatagttggtctacaatataag
aaaagttacgatgatgcagaatctctgaaaaccttacgctatggaaagattatgattatg
accgatcaggatcaagatggttctcacataaaaggcctgcttattaatttcatccatcac
aattggccatcacttttgaagcatggttttcttgaagagttcattactcctattgtaaag
gcaagcaaaaataagcaggaactttccttctacagtattcctgaatttgatgagtggaaa
aaacatatagaaaatcagaaagcctggaaaatcaagtactataaaggattgggtactagt
acagctaaagaagcaaaggaatattttgctgatatggaaaggcatcgcatcttgtttaga
tacgctggtcctgaagatgatgctgccattaccttggcattcagtaagaagaagattgat
gacagaaaagaatggttaacaaattttatggaagaccggagacagcgtaggctacatggc
ttaccagagcaatttttatatggtactgcaacaaagcatttgacttacaatgatttcatc
aacaaggaattgattctcttctcaaactcagacaatgaaagatctataccatctcttgtt
gatggctttaaacctggccagcggaaagttttatttacctgtttcaagaggaatgataaa
cgtgaagtaaaagttgcccagttggctggatctgttgctgagatgtcggcttatcatcat
ggagaacaagcattgatgatgactattgtgaatttggctcagaactttgtgggaagtaac
aacattaacttgcttcagcctattggtcagtttggaactcggcttcatggtggcaaagat
gctgcaagccctcgttatattttcacaatgttaagctctttagcaaggctactttttcct
gccgtggatgacaacctgcttaagttcctttatgatgataatcaacgtgtagagcctgag
tggtatattcccataattcccatggttttaataaatggtgctgagggcattggtactgga
tgggcttgtaaactacccaactatgatgctagggaaattgtgaacaatgtcagacgaatg
ctagatggcttggatcctcatcccatgcttccaaactacaaaaactttaaagggacgatt
caagaacttggtcaaaaccagtatgcagtcagtggtgaaatatttgtagtggacagaaac
acagtagaaattacagagcttccagttagaacttggacacaggtatacaaagaacaggtt
ttagaacctatgctaaatggaacagataaaacaccagcattaatttctgattataaagaa
tatcatactgacacaactgtgaaatttgtggtgaaaatgactgaagagaaactagcgcaa
gcagaagctgctggactgcataaagtttttaaacttcaaactactcttacttgtaattcc
atggtactctttgatcatatgggatgtctgaagaaatatgaaactgtgcaagacattctg
aaagaattctttgatttacgattaagttattatggtttacgtaaggagtggcttgtggga
atgctgggagcagaatctacaaagcttaacaatcaagcccgtttcattttagagaagata
caagggaaaattactatagagaataggtcaaagaaagatttgattcaaatgttagtccag
agaggttatgaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaa
gaggatgaaacacaaaaccagcatgatgatagttcctccgattcaggaactccttcaggc
ccagattttaattatattttaaatatgtctctgtggtctcttactaaagaaaaagttgaa
gaactgattaaacagagagatgcaaaagggcgagaggtcaatgatcttaaaagaaaatct
ccttcagatctttggaaagaagatttagcagcgtttgttgaagaactggataaagtggaa
gctcaagaacgagaagatattctggctggaatgtctggaaaagcaattaaaggtaaagtt
ggcaaacctaaggtgaagaaactccaattggaagagacaatgccctcaccttatggcaga
agagtaattcctgaaattacagctatgaaggcagatgccagcaaaaagttgctgaagaag
aagaagggtgatcttgatactacagcagtaaaagtggaatttgatgaagaattcagtgga
gtgccagtagaaggtgcaggagaagaggcattgattccgtcagctcctataaataaaggc
cccaaacccaaaagggagaagaaggagcctggtaccagagtgagaaaaacacccacatca
tctggtaaacctagtgcaaagaaagtgaagaaacggaatccttggtcagatgatgaatcc
aagtcagaaagtgacttggaagaaacagaacctgtggttattccaagagattctttgctt
aggagagcagccgccgaaagacctaaatacacatttgatttctcagaagaagaggatgat
gatgctgatgatgatgatgatgacaataatgatttagaagaattgaaagttaaagcatct
cccataacaaatgatggggaagatgaatttgttccttcagatgggttagataaagatgaa
tatacattttcaccaggcaaatcaaaagccactccagaaaaatctttgcatgacaaaaaa
agtcaggattttggaaatctcttttcatttccttcatattctcagaagtcagaagatgat
tcagctaaatttgacagtaatgaagaagattctgcttctgttttctcaccatcatttggt
ctgaaacagatagataaagttccaagtaaaacagtagctgctaaaaagggaaaaccgtct
tcagatacagcccctaagcccaagagagcccccaaacagaagaaagtagtagaggctgta
aactctgactcagattcagaatttggcattccaaagaagactacaccaccaaaaggtaaa
ggccgaggggcaaagaaaaggaaagcatctggctctgaaaatgaaggcgactataaccct
ggcaggaaaacatccaaaacagcaagcaagaaaccgaagaaaacatcctttgatcaggat
tcagatgtggacatcttcccctcagacttcccttctgagccaccttctctgccacgaacc
ggtcgggctaggaaagaagtaaaatattttgcagagtctgatgaagaagaagaagatgtt
gattttgcaatgtttaattaa
DBGET
integrated database retrieval system
