Macaca nemestrina (pig-tailed macaque): 105491847
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Entry
105491847 CDS
T08765
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X1
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
mni
Macaca nemestrina (pig-tailed macaque)
Pathway
mni01521
EGFR tyrosine kinase inhibitor resistance
mni04062
Chemokine signaling pathway
mni04081
Hormone signaling
mni04148
Efferocytosis
mni04151
PI3K-Akt signaling pathway
mni04217
Necroptosis
mni04550
Signaling pathways regulating pluripotency of stem cells
mni04630
JAK-STAT signaling pathway
mni04658
Th1 and Th2 cell differentiation
mni04659
Th17 cell differentiation
mni04725
Cholinergic synapse
mni04917
Prolactin signaling pathway
mni04920
Adipocytokine signaling pathway
mni04933
AGE-RAGE signaling pathway in diabetic complications
mni04935
Growth hormone synthesis, secretion and action
mni05140
Leishmaniasis
mni05145
Toxoplasmosis
mni05152
Tuberculosis
mni05161
Hepatitis B
mni05164
Influenza A
mni05167
Kaposi sarcoma-associated herpesvirus infection
mni05168
Herpes simplex virus 1 infection
mni05200
Pathways in cancer
mni05207
Chemical carcinogenesis - receptor activation
mni05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mni05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mni00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
105491847 (JAK2)
04151 PI3K-Akt signaling pathway
105491847 (JAK2)
09133 Signaling molecules and interaction
04081 Hormone signaling
105491847 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
105491847 (JAK2)
09143 Cell growth and death
04217 Necroptosis
105491847 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
105491847 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
105491847 (JAK2)
04659 Th17 cell differentiation
105491847 (JAK2)
04062 Chemokine signaling pathway
105491847 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
105491847 (JAK2)
04917 Prolactin signaling pathway
105491847 (JAK2)
04935 Growth hormone synthesis, secretion and action
105491847 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
105491847 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105491847 (JAK2)
05207 Chemical carcinogenesis - receptor activation
105491847 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
105491847 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
105491847 (JAK2)
05164 Influenza A
105491847 (JAK2)
05168 Herpes simplex virus 1 infection
105491847 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
105491847 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
105491847 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
105491847 (JAK2)
05140 Leishmaniasis
105491847 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
105491847 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
105491847 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
105491847 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mni01001
]
105491847 (JAK2)
Enzymes [BR:
mni01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
105491847 (JAK2)
Protein kinases [BR:
mni01001
]
Non-receptor tyrosine kinases
JAK family [OT]
105491847 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
105491847
NCBI-ProteinID:
XP_011756866
Ensembl:
ENSMNEG00000031180
UniProt:
A0A2K6BRZ3
LinkDB
All DBs
Position
Unknown
AA seq
1132 aa
AA seq
DB search
MGMACLTMTEMEGTSTSSIYQNGDISGNANSMKQIDPVLQVYLYHSLGKSEADYLTFPSG
EYVAEEICIAASKACGITPVYHNMFALMSETERIWYPPNHVFHIDESTRHNVLYRIRFYF
PRWYCSGSNRAYRHGISRGAEAPLLDDFVMSYLFAQWRHDFVHGWIKVPVTHETQEECLG
MAVLDMMRIAKENDQTPLAIYNSISYKTFLPECIRAKIQDYHILTRKRIRYRFRRFIQQF
SQCKATARNLKLKYLINLETLQSAFYTEKFEVKEPGSGPSGEEIFATIIITGNGGIQWSR
GKHKESETLTEQDLQLYCDFPNIIDVSIKQANQEGSDESRVVTIHKQDGKNLEIELSSLR
EALSFVSLIDGYYRLTADAHHYLCKEVAPPTVLENIQSNCHGPISMDFAISKLKKAGNQT
GLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNC
YQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKI
RNEDLIFNESLGQGTFTKIFKGIRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSKLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWA
MHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVP
PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAEL
ANLINNCMDYEPDFRPSFRAVIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRD
PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE
ILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI
CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW
YAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
LLKNNGRLPRPDGCPDEIYMIMTECWNNNVNLRPSFRDLALRVDQIRDNMAG
NT seq
3399 nt
NT seq
+upstream
nt +downstream
nt
atgggaatggcctgccttactatgacagaaatggagggaacatccacatcttctatatat
cagaatggtgatatttctggaaatgccaattctatgaagcaaatagatccagtccttcag
gtgtatctttaccattcccttgggaaatctgaggcagattatctgacctttccatctggg
gagtatgttgcagaagaaatctgtattgctgcttctaaagcttgtggtatcacacctgtg
tatcataatatgtttgctttaatgagtgaaacagaaaggatctggtatccacccaaccac
gtcttccatatagatgagtcaaccaggcataatgtactctacagaataagattttacttt
cctcgttggtattgcagcggcagcaacagagcctatcggcatggaatatctcgaggtgct
gaagctcctcttcttgatgactttgtcatgtcttacctctttgctcagtggcggcatgat
tttgtgcatggatggataaaagtacctgtgactcatgaaacacaggaagaatgtcttggg
atggcagtgttagatatgatgagaatagccaaagaaaatgatcaaaccccactggccatc
tataattctatcagctacaagacattcttaccagaatgtattcgagcaaagatccaagac
tatcatattttgacaaggaagcgaataaggtacagatttcgcagatttattcagcagttc
agccaatgcaaagccactgctagaaacttgaaacttaagtatcttataaatctggaaacc
ctgcagtctgccttctacacagagaaatttgaagtaaaagaacctggaagtggtccttca
ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga
gggaaacataaagaaagtgagacactgacagaacaggatttacaattatattgcgatttt
cctaatattattgatgtcagtattaagcaagcaaaccaagagggttcagatgaaagccga
gttgtaactatccataagcaagatggtaaaaatctggaaattgaacttagctcattaagg
gaagctttgtctttcgtgtcattaattgatggatattatagattaactgcagatgcacat
cattacctctgtaaagaagtagcacctccaacagtgcttgaaaatatacaaagcaactgt
catggcccaatttcgatggattttgccattagtaaactgaagaaagcaggtaatcagact
ggactgtatgtacttcgatgcagtcctaaggactttaataaatattttctgacttttgct
gtcgagcgagaaaatgtcattgaatataaacactgtttgattacaaaaaatgagaatgaa
gagtacaacctcagtgggacaaagaagaacttcagcagtcttaaagatcttttgaattgt
taccagatggaaaccgttcgctcagacaatataattttccagtttactaagtgctgtccc
ccaaagccaaaagataaatcaaaccttctagtcttcagaacgaatggtgtttctgatgta
ccaacctcaccaacattacagaggcctactcatatgaaccaaatggtgtttcacaaaatc
agaaatgaagatttgatatttaatgaaagccttggccaaggcactttcacaaagattttt
aaaggcatacgaagagaagtaggagactatggtcaacttcatgaaacagaagttctttta
aaagttctggataaagcacatagaaactattcagagtctttctttgaagcagcaagcatg
atgagcaagctttctcacaagcatttggttttaaattatggagtatgtgtctgtggagag
gagaatattctggttcaggagtttgtaaaatttggatcactagatacatacctgaaaaag
aataaaaattgtataaatatattatggaaacttgaagttgcgaaacagttggcatgggcc
atgcattttctagaagaaaacacccttattcatgggaatgtgtgcgccaaaaatattcta
cttatcagagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcct
ggcattagtattacagttttgccaaaggacattcttcaggagagaataccatgggtacca
cctgaatgcattgaaaatcctaaaaatttaaatttggcaacagacaaatggagttttggt
accactttgtgggaaatctgcagtggaggagataaacctctaagtgccctggattctcaa
agaaagctgcaattttatgaagataggcaccagcttcctgcaccaaagtgggcagaatta
gcaaaccttataaataattgtatggattatgaacccgatttcaggccttctttcagagcc
gtcatacgagatcttaacagtttgtttactccagattatgaactattaacagaaaatgac
atgttaccaaatatgaggataggtgccctagggttttctggtgcctttgaagacagggat
cctacacagtttgaagagagacatttgaaatttctacagcaacttggcaagggtaacttt
gggagtgtggagatgtgccggtatgaccctctacaggacaacactggggaggtggtggct
gtaaaaaagcttcagcatagtactgaagagcacctgagagactttgaaagggaaattgaa
atcctgaaatccctacagcatgacaacattgtaaagtacaagggagtgtgctacagtgct
ggtcggcgtaatctaaaattaattatggaatatttaccatatggaagtttacgagactat
cttcaaaaacataaagaacggatagatcacaaaaaacttctgcagtacacatctcagata
tgcaagggtatggagtatcttggtacaaaaaggtatatccacagggatctggcaacaaga
aatatattggtggagaatgagaacagagttaaaattggagattttgggttaaccaaagtc
ttgccacaagacaaagaatactataaagtaaaagaacctggtgaaagtcccatattctgg
tatgctccagaatcactgacagagagcaagttttctgtggcctcagatgtttggagcttt
ggagtggttctgtatgaacttttcacatacattgagaagagtaaaagtccaccagcggaa
tttatgcgtatgattggcaatgataaacaaggacagatgatcgtgttccatttgatagaa
cttttgaagaataatggaagattaccaagaccagatggatgcccagatgagatttatatg
atcatgacagaatgctggaacaataatgtaaatctacgcccctcctttagagatctagct
cttcgagtggatcaaataagggataacatggctggatga
DBGET
integrated database retrieval system
