Macaca nemestrina (pig-tailed macaque): 105493061
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Entry
105493061 CDS
T08765
Symbol
EGFR
Name
(RefSeq) epidermal growth factor receptor isoform X1
KO
K04361
epidermal growth factor receptor [EC:
2.7.10.1
]
Organism
mni
Macaca nemestrina (pig-tailed macaque)
Pathway
mni01521
EGFR tyrosine kinase inhibitor resistance
mni01522
Endocrine resistance
mni03272
Virion - Hepatitis viruses
mni04010
MAPK signaling pathway
mni04012
ErbB signaling pathway
mni04014
Ras signaling pathway
mni04015
Rap1 signaling pathway
mni04020
Calcium signaling pathway
mni04066
HIF-1 signaling pathway
mni04068
FoxO signaling pathway
mni04072
Phospholipase D signaling pathway
mni04144
Endocytosis
mni04151
PI3K-Akt signaling pathway
mni04510
Focal adhesion
mni04518
Integrin signaling
mni04519
Cadherin signaling
mni04520
Adherens junction
mni04540
Gap junction
mni04630
JAK-STAT signaling pathway
mni04810
Regulation of actin cytoskeleton
mni04912
GnRH signaling pathway
mni04915
Estrogen signaling pathway
mni04921
Oxytocin signaling pathway
mni04926
Relaxin signaling pathway
mni04928
Parathyroid hormone synthesis, secretion and action
mni04934
Cushing syndrome
mni05160
Hepatitis C
mni05163
Human cytomegalovirus infection
mni05165
Human papillomavirus infection
mni05171
Coronavirus disease
mni05200
Pathways in cancer
mni05205
Proteoglycans in cancer
mni05206
MicroRNAs in cancer
mni05207
Chemical carcinogenesis - receptor activation
mni05208
Chemical carcinogenesis - reactive oxygen species
mni05210
Colorectal cancer
mni05212
Pancreatic cancer
mni05213
Endometrial cancer
mni05214
Glioma
mni05215
Prostate cancer
mni05218
Melanoma
mni05219
Bladder cancer
mni05223
Non-small cell lung cancer
mni05224
Breast cancer
mni05225
Hepatocellular carcinoma
mni05226
Gastric cancer
mni05230
Central carbon metabolism in cancer
mni05231
Choline metabolism in cancer
mni05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
mni00001
]
09120 Genetic Information Processing
09125 Information processing in viruses
03272 Virion - Hepatitis viruses
105493061 (EGFR)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
105493061 (EGFR)
04012 ErbB signaling pathway
105493061 (EGFR)
04014 Ras signaling pathway
105493061 (EGFR)
04015 Rap1 signaling pathway
105493061 (EGFR)
04630 JAK-STAT signaling pathway
105493061 (EGFR)
04066 HIF-1 signaling pathway
105493061 (EGFR)
04068 FoxO signaling pathway
105493061 (EGFR)
04020 Calcium signaling pathway
105493061 (EGFR)
04072 Phospholipase D signaling pathway
105493061 (EGFR)
04151 PI3K-Akt signaling pathway
105493061 (EGFR)
09133 Signaling molecules and interaction
04518 Integrin signaling
105493061 (EGFR)
04519 Cadherin signaling
105493061 (EGFR)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
105493061 (EGFR)
09144 Cellular community - eukaryotes
04510 Focal adhesion
105493061 (EGFR)
04520 Adherens junction
105493061 (EGFR)
04540 Gap junction
105493061 (EGFR)
09142 Cell motility
04810 Regulation of actin cytoskeleton
105493061 (EGFR)
09150 Organismal Systems
09152 Endocrine system
04912 GnRH signaling pathway
105493061 (EGFR)
04915 Estrogen signaling pathway
105493061 (EGFR)
04921 Oxytocin signaling pathway
105493061 (EGFR)
04926 Relaxin signaling pathway
105493061 (EGFR)
04928 Parathyroid hormone synthesis, secretion and action
105493061 (EGFR)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105493061 (EGFR)
05206 MicroRNAs in cancer
105493061 (EGFR)
05205 Proteoglycans in cancer
105493061 (EGFR)
05207 Chemical carcinogenesis - receptor activation
105493061 (EGFR)
05208 Chemical carcinogenesis - reactive oxygen species
105493061 (EGFR)
05230 Central carbon metabolism in cancer
105493061 (EGFR)
05231 Choline metabolism in cancer
105493061 (EGFR)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
105493061 (EGFR)
09162 Cancer: specific types
05210 Colorectal cancer
105493061 (EGFR)
05212 Pancreatic cancer
105493061 (EGFR)
05225 Hepatocellular carcinoma
105493061 (EGFR)
05226 Gastric cancer
105493061 (EGFR)
05214 Glioma
105493061 (EGFR)
05218 Melanoma
105493061 (EGFR)
05219 Bladder cancer
105493061 (EGFR)
05215 Prostate cancer
105493061 (EGFR)
05213 Endometrial cancer
105493061 (EGFR)
05224 Breast cancer
105493061 (EGFR)
05223 Non-small cell lung cancer
105493061 (EGFR)
09172 Infectious disease: viral
05160 Hepatitis C
105493061 (EGFR)
05171 Coronavirus disease
105493061 (EGFR)
05163 Human cytomegalovirus infection
105493061 (EGFR)
05165 Human papillomavirus infection
105493061 (EGFR)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
105493061 (EGFR)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
105493061 (EGFR)
01522 Endocrine resistance
105493061 (EGFR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mni01001
]
105493061 (EGFR)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mni04147
]
105493061 (EGFR)
Enzymes [BR:
mni01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
105493061 (EGFR)
Protein kinases [BR:
mni01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
105493061 (EGFR)
Exosome [BR:
mni04147
]
Exosomal proteins
Exosomal proteins of colorectal cancer cells
105493061 (EGFR)
Exosomal proteins of pancreatic cancer cells
105493061 (EGFR)
Exosomal proteins of bladder cancer cells
105493061 (EGFR)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Kinase-like
ABC1
GAPT
Motif
Other DBs
NCBI-GeneID:
105493061
NCBI-ProteinID:
XP_011758798
Ensembl:
ENSMNEG00000022279
UniProt:
A0A2K6B1P2
LinkDB
All DBs
Position
Unknown
AA seq
1210 aa
AA seq
DB search
MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEV
VLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALA
VLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSEFLSNMSMDF
QNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGC
TGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYV
VTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDTLSINATNIKHFK
NCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAF
ENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKL
FGTSSQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCQNVSRGRECVDKCN
ILEGEPREFVENSECIQCHPECLPQVMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVM
GENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCARNGPKIPSIATGMVGALLLLLVV
ALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGS
GAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGI
CLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAA
RNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSY
GVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPK
FRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQ
QGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTED
SIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLN
TVQPTCVNSTFDSPAHWAQKGSHHISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRV
APQSSEFIGA
NT seq
3633 nt
NT seq
+upstream
nt +downstream
nt
atgcgaccctccgggacggccggggccgcgctcctggcgctgctggctgcgctctgcccc
gcgagtcgggctctggaggaaaagaaagtttgccaaggcacgagtaacaaactcacgcag
ttgggcacttttgaagatcattttctcagcctccagaggatgttcaataactgtgaggtg
gtccttgggaatttggaaattacctacgtgcagaggaattatgatctttccttcttaaag
accatccaggaggtggctggttatgtcctcatcgccctcaacacagtggagcggattcct
ttggaaaacctgcagatcatcagaggaaacatgtactatgaaaattcctatgccttagca
gtcttatctaactatgatgcaaataaaaccggactgaaggagctgcccatgagaaactta
caggaaatcctgcatggcgccgtgcggttcagcaacaaccctgctctgtgcaacgtggag
agcatccagtggcgggacatagtcagcagcgagtttctcagcaacatgtcgatggacttc
cagaaccacctgggcagctgccaaaagtgtgatccaagctgtcccaatgggagctgctgg
ggtgcaggagaggagaactgccagaaactgaccaagatcatctgtgcccagcagtgctcc
gggcgctgccgcggcaagtcccccagtgactgctgccacaaccagtgtgccgcgggctgc
acgggcccccgggagagcgactgcctggtctgccgcaaattccgagacgaagccacgtgc
aaggacacctgccccccactcatgctctacaaccccaccacataccagatggatgtgaac
cccgagggcaaatacagctttggtgccacctgcgtgaagaagtgtccccgtaattatgtg
gtgacagatcacggctcgtgcgtccgagcctgcggggccgacagctatgagatggaggaa
gacggcgtccgcaagtgtaagaagtgcgaagggccttgccgcaaagtgtgtaatggaata
ggtattggtgaatttaaagacacactctccataaatgctacaaatattaaacacttcaaa
aactgcacctccatcagtggcgatctccacatcctgccggtggcatttaggggtgactcc
ttcacacacactccgcctctggatccacaggaactggatattctgaaaaccgtaaaggaa
atcacagggtttttgctgattcaggcttggcctgaaaacaggacggacctccatgctttt
gagaacctagaaatcatacgtggcaggaccaagcaacacggtcagttttctcttgcggtc
gtcagcctgaacataacatccttgggattacgctccctcaaggagataagcgatggagat
gtgataatttcaggaaacaaaaatttgtgctatgcaaatacaataaactggaaaaaactg
tttgggacctccagtcagaaaaccaaaattataagcaacagaggtgaaaacagctgcaag
gccacgggccaggtctgccatgccttgtgctcccccgagggctgctggggcccggagccc
agggactgcgtctcctgccagaatgtcagccgaggcagagaatgcgtggacaagtgcaac
atcctggagggcgagccaagggagtttgtggagaactctgagtgcatacagtgccaccca
gaatgcctgccccaggtcatgaacatcacctgcacaggacggggaccagacaactgtatc
cagtgtgcccactacattgacggcccccactgcgtcaagacctgcccagcaggagtcatg
ggagaaaacaacaccctggtctggaagtacgcagacgccggccacgtgtgccacctgtgc
catccaaactgcacctacggatgcactgggccaggtcttgaaggctgtgcaaggaacggg
cctaagatcccatccatcgccactgggatggtgggggccctcctcttgctgctggtggtg
gccctggggatcggcctcttcatgcgaaggcgccacatcgttcggaagcgcacactgcgg
aggctgctgcaggagagggagcttgtggagcctcttacgcccagtggagaagctcccaac
caagctctcttgaggatcttgaaggaaactgaattcaagaagatcaaagtgctgggctcc
ggtgcgttcggaactgtgtataagggactctggatcccagaaggtgagaaagttaaaatt
cccgtcgctatcaaggaattaagagaagcaacatctccgaaagccaacaaggaaatcctc
gatgaagcctacgtgatggccagcgtggacaacccccatgtgtgccgcctgctgggcatc
tgcctcacctccaccgtgcagctcattacgcagctcatgcccttcggctgcctcctggac
tacgtccgggaacacaaggacaatatcggctcccagtacctgctcaactggtgtgtgcag
attgcaaagggcatgaactacttggaggaccggcgcttggtgcaccgcgacctggcagcc
aggaacgtactggtgaaaacgccacagcatgtcaagatcacggatttcgggctggccaaa
ctgctgggtgcagaagagaaagaataccatgcagaaggaggcaaagtgcctatcaagtgg
atggcattggaatcaattttacaccgaatttatacccaccagagtgatgtctggagctac
ggggtaaccgtttgggagttgatgacctttggatccaagccatatgacggaatccctgcc
agcgagatctcctccatcctggagaaaggagaacgcctcccccagccacccatatgtacc
atcgatgtctacatgatcatggtcaagtgctggatgatagacgcagatagtcgcccaaag
ttccgtgagttgatcattgaattctccaaaatggcccgagatccccagcgctaccttgtt
attcagggggatgaaagaatgcatttgccaagccctacagactccaacttctaccgtgcc
ctgatggatgaagaagacatggacgacgtggtggatgccgacgagtacctcatcccacag
cagggcttcttcagcagcccctccacgtcacggactcccctcctgagctctctgagtgca
accagcaacaattccactgtggcttgcattgatagaaatgggctgcaaagctgtcccatc
aaggaagacagcttcttacagcgatacagctcagaccccacaggcgccttgactgaggac
agcatagacgacaccttcctcccagtgcctgaatacataaaccagtccgttcccaaaagg
cccgctggctctgtgcagaatcctgtctatcacaatcagcctctgaaccctgcgcccagc
agagacccacactaccaggacccccacagcaccgcagtgggcaaccccgagtatctcaac
actgtccagcccacctgtgtcaacagcacattcgacagccctgctcattgggcccagaaa
ggcagccaccacattagcctggacaaccctgactaccagcaggacttctttcccaaggaa
gccaagccaaatggcatctttaagggctccacagctgaaaatgcagaatacctaagggtc
gcaccacaaagcagtgaatttattggagcatga
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integrated database retrieval system
