Macaca nemestrina (pig-tailed macaque): 105493427
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Entry
105493427 CDS
T08765
Symbol
ATP2A2
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform X1
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
mni
Macaca nemestrina (pig-tailed macaque)
Pathway
mni04020
Calcium signaling pathway
mni04022
cGMP-PKG signaling pathway
mni04024
cAMP signaling pathway
mni04148
Efferocytosis
mni04260
Cardiac muscle contraction
mni04261
Adrenergic signaling in cardiomyocytes
mni04380
Osteoclast differentiation
mni04919
Thyroid hormone signaling pathway
mni04972
Pancreatic secretion
mni05010
Alzheimer disease
mni05017
Spinocerebellar ataxia
mni05022
Pathways of neurodegeneration - multiple diseases
mni05410
Hypertrophic cardiomyopathy
mni05412
Arrhythmogenic right ventricular cardiomyopathy
mni05414
Dilated cardiomyopathy
mni05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mni00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
105493427 (ATP2A2)
04024 cAMP signaling pathway
105493427 (ATP2A2)
04022 cGMP-PKG signaling pathway
105493427 (ATP2A2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
105493427 (ATP2A2)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
105493427 (ATP2A2)
09153 Circulatory system
04260 Cardiac muscle contraction
105493427 (ATP2A2)
04261 Adrenergic signaling in cardiomyocytes
105493427 (ATP2A2)
09154 Digestive system
04972 Pancreatic secretion
105493427 (ATP2A2)
09158 Development and regeneration
04380 Osteoclast differentiation
105493427 (ATP2A2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
105493427 (ATP2A2)
05017 Spinocerebellar ataxia
105493427 (ATP2A2)
05022 Pathways of neurodegeneration - multiple diseases
105493427 (ATP2A2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
105493427 (ATP2A2)
05412 Arrhythmogenic right ventricular cardiomyopathy
105493427 (ATP2A2)
05414 Dilated cardiomyopathy
105493427 (ATP2A2)
05415 Diabetic cardiomyopathy
105493427 (ATP2A2)
Enzymes [BR:
mni01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
105493427 (ATP2A2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
105493427
NCBI-ProteinID:
XP_011759347
Ensembl:
ENSMNEG00000031586
UniProt:
A0A2K6BVP0
LinkDB
All DBs
Position
Unknown
AA seq
1042 aa
AA seq
DB search
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGV
KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL
NPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVTFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVL
LIMPLVIWVYSTDTNFSDMFWS
NT seq
3129 nt
NT seq
+upstream
nt +downstream
nt
atggagaacgcgcacacaaagacggtagaggaggtgctgggccacttcggcgtcaacgag
agtacggggctgagcctggagcaggtcaagaagctcaaggagagatggggctccaacgag
ttaccggctgaagaaggaaaaaccttgctggaacttgtgattgagcagtttgaagacttg
ctagttaggattttattactggcagcatgtatatcttttgttttggcttggtttgaagaa
ggtgaagaaacaattacagcctttgtagaaccttttgtaattttactcatattagtagcc
aatgcaattgtgggtgtatggcaggaaagaaatgctgaaaatgccattgaagcccttaag
gaatatgagcctgaaatgggcaaagtgtatcgacaggacagaaagagtgtacagcggatt
aaagctaaagacatagttcctggtgatattgtagaaattgctgttggtgacaaagttcct
gctgatataaggttaacttccatcaaatctaccacactaagagttgaccagtcgattctc
acaggtgagtctgtctctgtcatcaagcacactgaccccgtccctgacccacgagctgtc
aaccaagataaaaagaacatgctgttttctggtacaaacattgctgctgggaaagctatg
ggagtggtggtagcaactggagttaacactgaaattggcaagatccgggatgaaatggtg
gcaacagaacaggagagaacaccgcttcagcaaaaactagatgaatttggggaacagctt
tccaaagtcatctcccttatttgcattgcagtctggatcataaatatcggtcacttcaat
gacccagttcatggagggtcctggatcagaggtgctatttactactttaaaattgcagtg
gccctggctgtagcagccattcctgaaggtctgcctgcagtcatcaccacctgcctggct
cttggaactcgcagaatggcaaagaaaaatgctattgttcgaagcctcccgtctgtggaa
acccttggttgtacttctgttatctgctcagacaagactggtacacttacaacaaaccag
atgtcagtctgcaggatgttcattctggacagagtggaaggtgatacttgttcccttaat
gaatttaccataactggatcaacttatgcacctattggagaagtgcataaagatgataaa
ccagtgaaatgtcaccagtatgatgggctggtagaattagcaacaatttgtgctctttgt
aatgactctgctttggattacaatgaggcaaagggtgtatatgaaaaagttggagaagct
acagagactgctctcacttgcctagtagagaagatgaatgtatttgataccgaattgaag
ggtctttctaaaatagaacgtgcaaatgcctgcaactcagtcattaaacagctgatgaaa
aaggaattcactctcgagttttcacgtgacagaaagtcaatgtcggtttattgtacacca
aataaaccaagcaggacatcaatgagcaagatgtttgtgaagggtgctcctgaaggtgtc
attgacaggtgcacccacattcgagttggaagtactaaggttcctatgacctctggagtc
aaacagaagatcatgtctgtcattcgagagtggggtagtggcagcgacaccctgcgatgc
ctggccctggccactcacgacaacccactgagaagagaagaaatgcaccttgaagactct
gccaactttattaaatacgagaccaatctgaccttcgttggctgcgtgggcatgctggat
cctccaagaatcgaggtggcctcctccgtgaagctgtgccggcaagcaggcatccgggtc
atcatgatcactggggacaacaagggcactgctgtggccatctgtcgccgcatcggcatc
ttcgggcaggatgaggatgtgacgtcaaaagctttcacaggccgggagtttgatgaactc
aacccctctgcccagcgagatgcctgcctgaacgcccgctgttttgctcgagttgaaccc
tcccacaaatctaaaattgtagaatttcttcagtcttttgatgagattacagctatgact
ggtgatggcgtgaacgatgctcctgctctgaagaaatctgagattggcattgctatgggc
tctggcactgcggtggctaaaactgcctctgagatggtcttggcggatgacaacttctcc
accatagtggctgccgttgaggaggggcgggcaatctacaacaacatgaaacagttcatc
cgctacctcatctcatccaacgttggggaagttgtctgtattttcctgacagcagccctt
ggatttcccgaggctttgattcctgttcagctgctctgggtcaatctggtgacagatggc
ctgcctgccactgcactggggttcaaccctcctgatctggacatcatgaataaacctccc
cggaacccaaaggaaccattgatcagcgggtggctctttttccgttacttggctattggc
tgttacgtcggcgctgctaccgtgggtgctgctgcatggtggttcattgctgctgacggt
ggtccaagagtgaccttctaccagctgagtcatttcctacagtgtaaagaggacaacccg
gactttgaaggcgtggattgtgcaatctttgaatccccatacccgatgacaatggcgctc
tctgttctagtaactatagaaatgtgtaacgccctcaacagcttgtccgaaaaccagtcc
ttgctgaggatgcccccctgggagaacatctggctcgtgggctccatctgcctgtccatg
tcactccacttcctgatcctctatgtcgaacccttgccactcatcttccagatcacaccg
ctgaacgtgacccagtggctgatggtgctgaaaatctccttgcccgtgattctcatggac
gagacgctcaagtttgtggcccgcaactacctggaacctggtaaagagtgtgtgcagcct
gccaccaaatcctgctcgttctcggcatgcaccgatgggatttcctggccgtttgtgctg
ctcataatgcccctggtgatctgggtctatagcacagacactaactttagtgatatgttc
tggtcttga
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