Macaca nemestrina (pig-tailed macaque): 105495113
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Entry
105495113 CDS
T08765
Symbol
NOS1
Name
(RefSeq) nitric oxide synthase, brain isoform X1
KO
K13240
nitric-oxide synthase, brain [EC:
1.14.13.39
]
Organism
mni
Macaca nemestrina (pig-tailed macaque)
Pathway
mni00220
Arginine biosynthesis
mni00330
Arginine and proline metabolism
mni01100
Metabolic pathways
mni04020
Calcium signaling pathway
mni04145
Phagosome
mni04371
Apelin signaling pathway
mni04713
Circadian entrainment
mni04730
Long-term depression
mni04926
Relaxin signaling pathway
mni04970
Salivary secretion
mni05010
Alzheimer disease
mni05014
Amyotrophic lateral sclerosis
mni05022
Pathways of neurodegeneration - multiple diseases
mni05410
Hypertrophic cardiomyopathy
mni05412
Arrhythmogenic right ventricular cardiomyopathy
mni05414
Dilated cardiomyopathy
mni05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
mni00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
105495113 (NOS1)
00330 Arginine and proline metabolism
105495113 (NOS1)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
105495113 (NOS1)
04020 Calcium signaling pathway
105495113 (NOS1)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
105495113 (NOS1)
09150 Organismal Systems
09152 Endocrine system
04926 Relaxin signaling pathway
105495113 (NOS1)
09154 Digestive system
04970 Salivary secretion
105495113 (NOS1)
09156 Nervous system
04730 Long-term depression
105495113 (NOS1)
09159 Environmental adaptation
04713 Circadian entrainment
105495113 (NOS1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
105495113 (NOS1)
05014 Amyotrophic lateral sclerosis
105495113 (NOS1)
05022 Pathways of neurodegeneration - multiple diseases
105495113 (NOS1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
105495113 (NOS1)
05412 Arrhythmogenic right ventricular cardiomyopathy
105495113 (NOS1)
05414 Dilated cardiomyopathy
105495113 (NOS1)
05416 Viral myocarditis
105495113 (NOS1)
Enzymes [BR:
mni01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
105495113 (NOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
PDZ
PDZ_6
PDZ_2
Motif
Other DBs
NCBI-GeneID:
105495113
NCBI-ProteinID:
XP_011762639
Ensembl:
ENSMNEG00000035883
UniProt:
A0A2K6CM21
LinkDB
All DBs
Position
Unknown
AA seq
1434 aa
AA seq
DB search
MEDHMFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA
GDIILAVNGRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI
RVTQPLGPPTKAVDLSHQPSAGKEQPLAVDGASGPGNGPQHAQDDGQEAGSLPHANGLAP
RPPGQDPAKKAARVGLQGRGENNELLKEIEPVLNLLTSGSRGVKGGAPAKAEMKDMGIQV
DRDLDGKSHKPLPLGVENDRVFNDLWGKGNVPVVLNNPYSEKEQPPASGKQSPTKNGSPS
KCPRFLKVKNWETDVVLTDTLHLNSTLETGCTEYICMGSIMLPSQHIRRPEDVRTKEQLF
PLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIETTSTYQLKDTELIYGAKHAWRNASRC
VGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVW
NSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQ
IPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV
RDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT
ESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHV
WKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCE
IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQ
EERKSYKVRFNSVSSYSDSQKSSGDGPDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAF
GHAVDTLLEELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANN
SLISNDRSWKRNKFRLTYVAEAPELTQGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFV
RLHTNGNQELQYQPGDHLGVFPGNHEDLVNALIERLEDAPPVNQMVKVELLEERNTALGV
ISNWTDEHRLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATNEKEKQRLLVLSKGLQEY
EEWKWGKNPTIVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIV
SYRTRDGEGPIHHGVCSSWLNRIQADEVVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAP
FRSFWQQRQFDIQHKGMNPCPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSRE
PDKPKKYVQDILQEQLAESVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAE
DAGVFISRMRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDTDEVFSS
NT seq
4305 nt
NT seq
+upstream
nt +downstream
nt
atggaggatcacatgttcggtgttcagcaaatccagcccaatgtcatttctgttcgtctt
ttcaagcgcaaagttgggggcctgggattcctggtgaaggagcgggtcagtaagccaccc
gtgatcatctccgacctgattcgtgggggcgccgcggaacagagtggcctcatccaggcc
ggagacatcattcttgcggtcaacggccggcccttggtggacctgagctatgacagcgcc
ctggaggtactcagaggcattgcctccgagacccacgtggtcctcattctgaggggccct
gaaggcttcaccacgcacctggagaccacctttacaggtgatgggacccccaaaaccatc
cgggtgacgcagcccctgggtccccccaccaaagctgtggatctgtcccaccagccatca
gccggcaaagaacaaccgctggcagtggatggggcctcgggtcctgggaatgggcctcag
catgcccaagacgatgggcaggaggctggctcgctcccccatgccaacggcctggccccc
aggcccccgggccaggaccctgcaaagaaagcagccagagtcggcctccaaggcagaggg
gagaacaatgaactgctcaaggagatagagcctgtgctgaaccttctcaccagtgggagc
agaggggtcaagggaggggcacctgccaaggcagagatgaaagatatgggaatccaggtg
gacagagatttggacggcaaatcacacaaacctctgccccttggtgtggagaatgaccga
gtcttcaatgacctatgggggaagggcaatgtgcctgtggtcctcaacaacccatattca
gagaaggagcagccccctgcctcaggaaaacagtcccccacaaagaatggcagcccctcc
aagtgtccacgcttcctcaaagtcaagaactgggagactgacgtggttctcactgacacc
ctccaccttaacagcacattggaaacgggatgcactgagtacatctgcatgggctccatc
atgcttccttctcagcatatacggaggcctgaagatgtccgcacaaaagaacagctcttc
cctctcgccaaagagtttattgatcaatactattcatcaattaaaagatttggctccaaa
gcccacatggaaaggctggaagaggtgaacaaagagatcgaaaccactagcacctaccag
ctcaaggatacagagctcatctacggggccaagcatgcctggcggaatgcctcacgctgt
gtgggcaggatccagtggtccaagctgcaggtattcgatgctcgcgactgcaccacagcc
cacgggatgttcaactacatctgcaaccacgtcaagtatgccaccaacaaagggaacctc
aggtctgccatcaccatattcccccagaggacagacggcaagcacgacttccgagtctgg
aactcccagctcatccgctacgctggctacaagcagcccgacggctccaccctgggggac
ccggccaacgtgcagttcacagagatttgcatacagcagggctggaaacctccaagaggc
cgctttgatgtcctgccgctcctgcttcaggccaacggcaatgaccctgagctcttccag
attcctccagagctggtgttggaagttcccatcaggcaccccaagtttgagtggttcaag
gacctggggctgaagtggtacggcctccctgctgtgtccaacatgctcctggagattggc
ggcctggagttcagcgcctgtcccttcagtggctggtacatgggcacagagattggtgtc
cgtgactactgtgacaactcccgctacaatatcctggaggaagtggccaagaagatgaac
ttagacatgaggaagacgtcctcgctgtggaaggaccaggcgctggtggagatcaatatc
gcggttctctatagcttccagagtgacaaagtgaccattgttgaccatcactccgccacc
gagtccttcattaagcacatggagaacgagtaccgctgccggggaggctgccctgccgac
tgggtgtggattgtgccccccatgtctggaagcatcacccctgtgttccaccaggagatg
ctcaactaccggctcaccccctccttcgaataccagcctgatccctggaacacccacgtc
tggaaaggcaccaacgggacccccacaaagcggcgagccatcggcttcaagaaactggca
gaagctgtcaagttctcggccaagctgatggggcaggctatggccaagagggtcaaagca
accatcctgtatgccacggagacaggcaaatcgcaagcttatgccaagaccttgtgtgag
atcttcaaacacgcctttgatgccaaggtgatgtccatggaagaatatgacatcgtgcac
ctggaacatgaaactctggtcctcgtggttaccagcacctttggcaacggagatccccct
gagaatggggagaaatttggctgtgcgttgatggaaatgaggcaccccaactctgtgcag
gaagaaaggaagagctacaaggtccgattcaatagcgtctcctcctactctgactcccaa
aaatcatcaggcgatgggcccgacctcagagacaactttgagagtgctggacccctggcc
aatgtgaggttctcagtgtttggtcttggctcacgagcgtaccctcacttttgcgccttc
ggacatgctgtggacaccctcctggaagaactgggaggggagaggatcctgaagatgagg
gaaggggatgagctctgtgggcaggaagaggctttcaggacctgggccaagaaggtcttc
aaggcagcctgtgatgtcttctgtgtgggagatgatgtcaacattgaaaaggcgaacaat
tccctcatcagcaatgaccgcagctggaagagaaacaagttccgcctcacctatgtggcc
gaagctccagaactcacgcaaggtctatccaatgtccacaaaaagcgagtctcagctgcc
cgactccttagccgtcaaaacctccagagccctaaatccagtcggtcaactatcttcgtg
cgtctccacaccaacgggaatcaggagctgcagtaccagcctggggaccacctgggtgtc
ttccctggcaaccacgaggacctcgtgaatgccctgatcgagcggctggaggacgcaccc
cctgtcaaccagatggtgaaagtggagctgctggaggagcggaacacagctttaggcgtc
atcagtaactggacagacgagcaccgcctcccaccctgcaccatcttccaggccttcaag
tactacctggacatcaccacgccaccaacgcccctgcagctgcagcagtttgcctcccta
gccaccaatgagaaggagaaacagcgtctgctggtcctcagcaagggtttgcaggagtat
gaggaatggaaatggggcaagaaccccaccatcgtggaggtgctggaggagttcccatcc
atccagatgccggccaccctgctcctgacccagctgtccctgctgcagccccgctactat
tccatcagctcctccccagacatgtaccctgatgaagtgcacctcactgtggccatcgtt
tcctaccgcactcgagatggagaaggaccaattcaccacggcgtgtgctcctcctggctc
aaccggatacaggctgacgaagtggtcccctgtttcgtgagaggagcacccagcttccac
ctgccccggaacccccaagtcccctgcatcctcgttggaccgggcaccggcattgcacct
ttccgaagcttctggcaacagcggcaatttgatatccaacacaaaggaatgaacccctgc
cccatggtcctggtcttcgggtgccggcaatccaagatagatcatatctacagggaagag
accttgcaggccaagaacaagggggtcttcagagagctgtacacggcttactcccgggag
ccagacaaaccaaagaagtacgtgcaggacatcctgcaggagcagctggcggagtctgtg
taccgagccctgaaggagcaagggggccacatttacgtctgtggggacgtcaccatggcc
gctgatgtcctcaaagccatccagcgcatcatgacccagcaggggaagctctcggcagag
gacgccggcgtgttcatcagtcggatgagggatgacaaccggtaccacgaggatattttc
ggagtcaccctgcgaacgtatgaagtgaccaaccgccttagatctgagtccattgccttc
attgaagagagcaaaaaagacaccgatgaggttttcagctcctaa
DBGET
integrated database retrieval system
