KEGG   Macaca nemestrina (pig-tailed macaque): 105496309
Entry
105496309         CDS       T08765                                 
Symbol
SRC
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src isoform X1
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
mni  Macaca nemestrina (pig-tailed macaque)
Pathway
mni01521  EGFR tyrosine kinase inhibitor resistance
mni01522  Endocrine resistance
mni04012  ErbB signaling pathway
mni04015  Rap1 signaling pathway
mni04062  Chemokine signaling pathway
mni04081  Hormone signaling
mni04137  Mitophagy - animal
mni04144  Endocytosis
mni04360  Axon guidance
mni04370  VEGF signaling pathway
mni04510  Focal adhesion
mni04520  Adherens junction
mni04530  Tight junction
mni04540  Gap junction
mni04611  Platelet activation
mni04613  Neutrophil extracellular trap formation
mni04625  C-type lectin receptor signaling pathway
mni04727  GABAergic synapse
mni04750  Inflammatory mediator regulation of TRP channels
mni04810  Regulation of actin cytoskeleton
mni04912  GnRH signaling pathway
mni04915  Estrogen signaling pathway
mni04917  Prolactin signaling pathway
mni04919  Thyroid hormone signaling pathway
mni04921  Oxytocin signaling pathway
mni04926  Relaxin signaling pathway
mni05100  Bacterial invasion of epithelial cells
mni05135  Yersinia infection
mni05152  Tuberculosis
mni05161  Hepatitis B
mni05163  Human cytomegalovirus infection
mni05167  Kaposi sarcoma-associated herpesvirus infection
mni05168  Herpes simplex virus 1 infection
mni05203  Viral carcinogenesis
mni05205  Proteoglycans in cancer
mni05207  Chemical carcinogenesis - receptor activation
mni05208  Chemical carcinogenesis - reactive oxygen species
mni05219  Bladder cancer
mni05417  Lipid and atherosclerosis
mni05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mni00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    105496309 (SRC)
   04015 Rap1 signaling pathway
    105496309 (SRC)
   04370 VEGF signaling pathway
    105496309 (SRC)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    105496309 (SRC)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    105496309 (SRC)
   04137 Mitophagy - animal
    105496309 (SRC)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105496309 (SRC)
   04520 Adherens junction
    105496309 (SRC)
   04530 Tight junction
    105496309 (SRC)
   04540 Gap junction
    105496309 (SRC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    105496309 (SRC)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    105496309 (SRC)
   04613 Neutrophil extracellular trap formation
    105496309 (SRC)
   04625 C-type lectin receptor signaling pathway
    105496309 (SRC)
   04062 Chemokine signaling pathway
    105496309 (SRC)
  09152 Endocrine system
   04912 GnRH signaling pathway
    105496309 (SRC)
   04915 Estrogen signaling pathway
    105496309 (SRC)
   04917 Prolactin signaling pathway
    105496309 (SRC)
   04921 Oxytocin signaling pathway
    105496309 (SRC)
   04926 Relaxin signaling pathway
    105496309 (SRC)
   04919 Thyroid hormone signaling pathway
    105496309 (SRC)
  09156 Nervous system
   04727 GABAergic synapse
    105496309 (SRC)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    105496309 (SRC)
  09158 Development and regeneration
   04360 Axon guidance
    105496309 (SRC)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    105496309 (SRC)
   05207 Chemical carcinogenesis - receptor activation
    105496309 (SRC)
   05208 Chemical carcinogenesis - reactive oxygen species
    105496309 (SRC)
   05203 Viral carcinogenesis
    105496309 (SRC)
  09162 Cancer: specific types
   05219 Bladder cancer
    105496309 (SRC)
  09172 Infectious disease: viral
   05161 Hepatitis B
    105496309 (SRC)
   05168 Herpes simplex virus 1 infection
    105496309 (SRC)
   05163 Human cytomegalovirus infection
    105496309 (SRC)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105496309 (SRC)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    105496309 (SRC)
   05152 Tuberculosis
    105496309 (SRC)
   05100 Bacterial invasion of epithelial cells
    105496309 (SRC)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105496309 (SRC)
   05418 Fluid shear stress and atherosclerosis
    105496309 (SRC)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    105496309 (SRC)
   01522 Endocrine resistance
    105496309 (SRC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mni01001]
    105496309 (SRC)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mni04131]
    105496309 (SRC)
Enzymes [BR:mni01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     105496309 (SRC)
Protein kinases [BR:mni01001]
 Non-receptor tyrosine kinases
  SRC family
   105496309 (SRC)
Membrane trafficking [BR:mni04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    105496309 (SRC)
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    105496309 (SRC)
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    105496309 (SRC)
  Macropinocytosis
   Kinases
    105496309 (SRC)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 SH2_1 ABC1 Haspin_kinase
Other DBs
NCBI-GeneID: 105496309
NCBI-ProteinID: XP_011764940
Ensembl: ENSMNEG00000027187
LinkDB
Position
Unknown
AA seq 553 aa
MGSNKSKPKDASQRRRSLEPAENAHGAGGGAFPASQTPSKPASADGHRGPSAAFAPAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKV
DVSQTWFTFRWLQREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESER
LLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQF
NSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGE
VWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEY
MSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVC
KVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR
VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYF
TSTEPQYQPGENL
NT seq 1662 nt   +upstreamnt  +downstreamnt
atgggcagcaacaagagcaagcccaaggatgccagccagcggcgccgcagcctggagccc
gccgagaacgcgcatggcgctggcgggggcgctttccccgcctcccagacccccagcaag
ccagcctcggccgacggccaccgcggccccagcgcggccttcgcccccgcggccgccgag
cccaagctgttcggaggcttcaactcctcggacaccgtcacctccccgcagagggcgggc
ccgctggccggtggagtgaccacctttgtggccctctatgactatgagtctaggacggag
acagacctgtccttcaagaaaggcgagcggctccagattgtcaacaacacgaggaaggtg
gatgtcagccagacctggttcacattcagatggctgcaaagagagggagactggtggctg
gcccactcgctcagcacgggacagacaggctacattcccagcaactacgtggcgccctcc
gactccatccaggccgaggagtggtattttggcaagatcaccagacgggagtcagagcgg
ttactgctcaatgcggagaacccgagagggaccttcctcgtgcgagaaagtgagaccaca
aaaggtgcctactgcctctcagtgtccgacttcgacaacgccaagggcctcaacgtgaag
cactacaagatccgcaagctggacagcggcggcttctacatcacctcccgcacccagttc
aacagcctgcagcagctggtggcctactactccaaacatgccgatggcctgtgccaccgc
ctcaccactgtgtgccccacatccaagcctcagactcagggcctggccaaggatgcctgg
gagatccctcgggagtcgctgcggctggaggtcaagctgggccagggctgctttggcgag
gtgtggatggggacctggaacggcactactagggtggccatcaaaaccctgaagcctggc
acgatgtctccagaggccttcctgcaggaggcccaggtcatgaagaagctgaggcatgag
aagctggtgcagttgtatgctgtggtttcggaggagcccatttacatcgtcacagagtac
atgagcaaggggagtttgctggactttctcaagggggagacgggcaagtacctgcggcta
cctcagctggtggacatggctgctcagatcgcctcaggcatggcatacgtggagcggatg
aactacgtccaccgggatcttcgtgcagccaacatcctggtgggagagaacctggtgtgc
aaagtggctgacttcgggctggctcggctcatcgaagacaatgagtacacggcccggcaa
ggtgccaaattccccatcaagtggacagctccggaagctgccctgtatggccgcttcacc
atcaagtcggacgtgtggtcctttgggatcctgctgactgagctcaccacaaagggacgg
gtgccctaccctgggatggtgaaccgcgaggtgctggaccaggtggaacggggctaccgg
atgccctgcccaccggagtgtcccgagtccctgcacgacctcatgtgccagtgctggcgg
aaggagcctgaggagcggcccaccttcgagtacctgcaggccttcctggaggactacttc
acgtccaccgagccccagtaccagcccggggagaacctctag

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