Macaca nemestrina (pig-tailed macaque): 105498012 Help Entry 105498012         CDS       T08765                                  Symbol PKLR Name (RefSeq) pyruvate kinase PKLR isoform X1   KO K12406   pyruvate kinase isozymes R/L [EC:2.7.1.40] Organism mni  Macaca nemestrina (pig-tailed macaque) Pathway mni00010   Glycolysis / Gluconeogenesis mni00620   Pyruvate metabolism mni01100   Metabolic pathways mni01200   Carbon metabolism mni01230   Biosynthesis of amino acids mni04910   Insulin signaling pathway mni04930   Type II diabetes mellitus mni04932   Non-alcoholic fatty liver disease mni04950   Maturity onset diabetes of the young Module mni_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate mni_M00002   Glycolysis, core module involving three-carbon compounds Brite KEGG Orthology (KO) [BR:mni00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     105498012 (PKLR)    00620 Pyruvate metabolism     105498012 (PKLR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     105498012 (PKLR)  09160 Human Diseases   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     105498012 (PKLR)    04950 Maturity onset diabetes of the young     105498012 (PKLR)    04932 Non-alcoholic fatty liver disease     105498012 (PKLR)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:mni04147]     105498012 (PKLR) Enzymes [BR:mni01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.40  pyruvate kinase      105498012 (PKLR) Exosome [BR:mni04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    105498012 (PKLR) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK PK_C IMPDH HpcH_HpaI Motif Other DBs NCBI-GeneID:  105498012 NCBI-ProteinID:  XP_011768036 Ensembl:  ENSMNEG00000009109 LinkDB All DBs Position Unknown AA seq 574 aa AA seqDB search MSIQENIPSLRRWSWVSKSQRDLAKSILIGAPGGPAGYLRRASVAQLTQELGTAFFQQQQ LPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFS HGSHEYHAESIANVREAVESFAASPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKG SQVLVTVDPAFRTRGNANTVWVDYPNIVGVVPVGGRIYIDDGLISLVVQKIGPEGLVTQV ENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAA LGPEGQGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC NLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKM QHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVIAIGAVEAAFKCCAAAIIVLTTTGRS AQLLSQYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESG KLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSIS NT seq 1725 nt NT seq  +upstreamnt  +downstreamnt atgtcgatccaggagaacataccatccctgcggcgctggtcatgggtctctaagtcccaa agagacttagcgaagtccatcctgattggggctccaggagggccagcggggtatcttcgg cgggctagtgtggcccaactgacccaggagctgggcactgccttcttccagcagcagcag ttgccagctgctatggcagacaccttcctggagcacctctgcctactggacattgactcc gagcccgtggctgctcgcagtaccagcatcattgccaccatcgggccggcatctcgctcc gtggagcgcctcaaggagatgatcaaggccgggatgaacattgcgcgactcaatttctcc cacggctcccacgagtaccacgctgagtccatcgccaacgtccgggaggcggtggagagc tttgcagcttccccgctcagctaccggcccgtggccatcgccctggacaccaagggaccg gagatccgcactgggatcctgcaggggggtccggagtcggaagtggagctggtgaagggc tcccaggtgctggtgactgtggaccccgcgtttcggacgcgggggaacgcgaacaccgtg tgggtggactaccccaatattgtcggggtcgtgcctgtggggggccgcatctacattgac gacgggctcatctccctagtggtccagaaaatcggcccagagggactggtgacccaagtg gagaacggtggcgtcctgggcagccgtaagggcgtgaacttgccgggggcccaggtggac ttgcccgggctgtccgagcaggacgtccgggacctgcgcttcggggtggagcatggagtg gacatcgtgtttgcctcctttgtgcggaaagccagcgatgtggctgctgtcagggctgct ctggggccggaaggacagggcatcaagatcatcagcaaaattgagaaccacgaaggcgtg aagaggtttgatgaaatcctggaggtgagcgacggtatcatggtggcacggggggaccta ggcatcgagattccagcagagaaggttttcctggctcagaagatgatgattgggcgctgc aacttggcgggcaagcctgttgtctgtgctacacagatgctggagagcatgattaccaag ccccggccaacgagggcagagacaagcgatgtggccaatgctgtgctagatggggccgac tgcatcatgctgtcaggggagactgccaaaggcaacttccctgtggaagccgtgaagatg cagcatgcgattgcccgggaggcagaggctgcagtgtaccaccggcagctgtttgaggag ctacgtcgggcagcgccactgagccgtgatcccactgaggtcatcgccattggcgccgtg gaggctgccttcaagtgctgtgctgctgccatcatcgtactgaccacaactggccgctca gcccagcttctgtctcagtaccgacctcgggcagcagtcattgctgtcacccgctctgcc caagctgcccgccaggtccacttatgccgaggagtcttccccttgctttaccgtgaacct ccagaagccatctgggcagatgacgtagatcgccgggtgcaatttggcattgaaagtgga aagctccgtggcttcctccgtgttggagacctggtgattgtggtgacaggctggcgacct ggctccggctacaccaacatcatgcgggtgctgagcatatcctga

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