KEGG   Mustela nigripes (black-footed ferret): 132001060
Entry
132001060         CDS       T09425                                 
Symbol
MAPK10
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
mnp  Mustela nigripes (black-footed ferret)
Pathway
mnp01522  Endocrine resistance
mnp04010  MAPK signaling pathway
mnp04012  ErbB signaling pathway
mnp04014  Ras signaling pathway
mnp04024  cAMP signaling pathway
mnp04068  FoxO signaling pathway
mnp04071  Sphingolipid signaling pathway
mnp04137  Mitophagy - animal
mnp04140  Autophagy - animal
mnp04141  Protein processing in endoplasmic reticulum
mnp04210  Apoptosis
mnp04215  Apoptosis - multiple species
mnp04217  Necroptosis
mnp04310  Wnt signaling pathway
mnp04380  Osteoclast differentiation
mnp04510  Focal adhesion
mnp04530  Tight junction
mnp04620  Toll-like receptor signaling pathway
mnp04621  NOD-like receptor signaling pathway
mnp04622  RIG-I-like receptor signaling pathway
mnp04625  C-type lectin receptor signaling pathway
mnp04657  IL-17 signaling pathway
mnp04658  Th1 and Th2 cell differentiation
mnp04659  Th17 cell differentiation
mnp04660  T cell receptor signaling pathway
mnp04664  Fc epsilon RI signaling pathway
mnp04668  TNF signaling pathway
mnp04722  Neurotrophin signaling pathway
mnp04723  Retrograde endocannabinoid signaling
mnp04728  Dopaminergic synapse
mnp04750  Inflammatory mediator regulation of TRP channels
mnp04910  Insulin signaling pathway
mnp04912  GnRH signaling pathway
mnp04914  Progesterone-mediated oocyte maturation
mnp04917  Prolactin signaling pathway
mnp04920  Adipocytokine signaling pathway
mnp04926  Relaxin signaling pathway
mnp04930  Type II diabetes mellitus
mnp04931  Insulin resistance
mnp04932  Non-alcoholic fatty liver disease
mnp04933  AGE-RAGE signaling pathway in diabetic complications
mnp04935  Growth hormone synthesis, secretion and action
mnp04936  Alcoholic liver disease
mnp05010  Alzheimer disease
mnp05012  Parkinson disease
mnp05016  Huntington disease
mnp05017  Spinocerebellar ataxia
mnp05020  Prion disease
mnp05022  Pathways of neurodegeneration - multiple diseases
mnp05132  Salmonella infection
mnp05133  Pertussis
mnp05135  Yersinia infection
mnp05142  Chagas disease
mnp05145  Toxoplasmosis
mnp05152  Tuberculosis
mnp05161  Hepatitis B
mnp05162  Measles
mnp05166  Human T-cell leukemia virus 1 infection
mnp05167  Kaposi sarcoma-associated herpesvirus infection
mnp05169  Epstein-Barr virus infection
mnp05170  Human immunodeficiency virus 1 infection
mnp05171  Coronavirus disease - COVID-19
mnp05200  Pathways in cancer
mnp05208  Chemical carcinogenesis - reactive oxygen species
mnp05210  Colorectal cancer
mnp05212  Pancreatic cancer
mnp05231  Choline metabolism in cancer
mnp05415  Diabetic cardiomyopathy
mnp05417  Lipid and atherosclerosis
mnp05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mnp00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    132001060 (MAPK10)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    132001060 (MAPK10)
   04012 ErbB signaling pathway
    132001060 (MAPK10)
   04014 Ras signaling pathway
    132001060 (MAPK10)
   04310 Wnt signaling pathway
    132001060 (MAPK10)
   04668 TNF signaling pathway
    132001060 (MAPK10)
   04068 FoxO signaling pathway
    132001060 (MAPK10)
   04071 Sphingolipid signaling pathway
    132001060 (MAPK10)
   04024 cAMP signaling pathway
    132001060 (MAPK10)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    132001060 (MAPK10)
   04137 Mitophagy - animal
    132001060 (MAPK10)
  09143 Cell growth and death
   04210 Apoptosis
    132001060 (MAPK10)
   04215 Apoptosis - multiple species
    132001060 (MAPK10)
   04217 Necroptosis
    132001060 (MAPK10)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    132001060 (MAPK10)
   04530 Tight junction
    132001060 (MAPK10)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    132001060 (MAPK10)
   04621 NOD-like receptor signaling pathway
    132001060 (MAPK10)
   04622 RIG-I-like receptor signaling pathway
    132001060 (MAPK10)
   04625 C-type lectin receptor signaling pathway
    132001060 (MAPK10)
   04660 T cell receptor signaling pathway
    132001060 (MAPK10)
   04658 Th1 and Th2 cell differentiation
    132001060 (MAPK10)
   04659 Th17 cell differentiation
    132001060 (MAPK10)
   04657 IL-17 signaling pathway
    132001060 (MAPK10)
   04664 Fc epsilon RI signaling pathway
    132001060 (MAPK10)
  09152 Endocrine system
   04910 Insulin signaling pathway
    132001060 (MAPK10)
   04920 Adipocytokine signaling pathway
    132001060 (MAPK10)
   04912 GnRH signaling pathway
    132001060 (MAPK10)
   04914 Progesterone-mediated oocyte maturation
    132001060 (MAPK10)
   04917 Prolactin signaling pathway
    132001060 (MAPK10)
   04926 Relaxin signaling pathway
    132001060 (MAPK10)
   04935 Growth hormone synthesis, secretion and action
    132001060 (MAPK10)
  09156 Nervous system
   04728 Dopaminergic synapse
    132001060 (MAPK10)
   04723 Retrograde endocannabinoid signaling
    132001060 (MAPK10)
   04722 Neurotrophin signaling pathway
    132001060 (MAPK10)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    132001060 (MAPK10)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    132001060 (MAPK10)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    132001060 (MAPK10)
   05208 Chemical carcinogenesis - reactive oxygen species
    132001060 (MAPK10)
   05231 Choline metabolism in cancer
    132001060 (MAPK10)
  09162 Cancer: specific types
   05210 Colorectal cancer
    132001060 (MAPK10)
   05212 Pancreatic cancer
    132001060 (MAPK10)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    132001060 (MAPK10)
   05170 Human immunodeficiency virus 1 infection
    132001060 (MAPK10)
   05161 Hepatitis B
    132001060 (MAPK10)
   05171 Coronavirus disease - COVID-19
    132001060 (MAPK10)
   05162 Measles
    132001060 (MAPK10)
   05167 Kaposi sarcoma-associated herpesvirus infection
    132001060 (MAPK10)
   05169 Epstein-Barr virus infection
    132001060 (MAPK10)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    132001060 (MAPK10)
   05135 Yersinia infection
    132001060 (MAPK10)
   05133 Pertussis
    132001060 (MAPK10)
   05152 Tuberculosis
    132001060 (MAPK10)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    132001060 (MAPK10)
   05142 Chagas disease
    132001060 (MAPK10)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    132001060 (MAPK10)
   05012 Parkinson disease
    132001060 (MAPK10)
   05016 Huntington disease
    132001060 (MAPK10)
   05017 Spinocerebellar ataxia
    132001060 (MAPK10)
   05020 Prion disease
    132001060 (MAPK10)
   05022 Pathways of neurodegeneration - multiple diseases
    132001060 (MAPK10)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    132001060 (MAPK10)
   05418 Fluid shear stress and atherosclerosis
    132001060 (MAPK10)
   05415 Diabetic cardiomyopathy
    132001060 (MAPK10)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    132001060 (MAPK10)
   04936 Alcoholic liver disease
    132001060 (MAPK10)
   04932 Non-alcoholic fatty liver disease
    132001060 (MAPK10)
   04931 Insulin resistance
    132001060 (MAPK10)
   04933 AGE-RAGE signaling pathway in diabetic complications
    132001060 (MAPK10)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    132001060 (MAPK10)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mnp01001]
    132001060 (MAPK10)
Enzymes [BR:mnp01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     132001060 (MAPK10)
Protein kinases [BR:mnp01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   132001060 (MAPK10)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like APH FTA2
Other DBs
NCBI-GeneID: 132001060
NCBI-ProteinID: XP_059231233
LinkDB
Position
1:complement(150309737..150903402)
AA seq 464 aa
MSLHLLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAA
VNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
NT seq 1395 nt   +upstreamnt  +downstreamnt
atgagcctccatttattgtactactgcagtgaaccaaccttggatgtgaaaattgccttt
tgtcagggattcgataaacaagtggatgtgtcatatattgccaaacattacaacatgagc
aaaagcaaagttgacaaccagttctacagtgtggaagtgggagactcaaccttcacagtt
ctcaagcgctaccagaatttgaagcctattggctctggggctcagggaatagtttgtgct
gcgtatgatgctgttcttgacagaaatgtggccattaagaagctcagcagaccttttcag
aaccaaacgcatgccaagagagcttaccgggagctggtcctcatgaagtgtgtgaaccat
aagaacattattagtttattaaatgtcttcacaccccagaaaacattggaggagttccaa
gatgtttacttagtcatggaactgatggatgccaacttgtgtcaggtgattcagatggaa
ttagaccatgagcgaatgtcttacctgctataccaaatgttgtgtggcatcaagcacctt
cattctgctggaattattcacagggatttaaaaccaagtaacattgtagtcaagtctgat
tgtacattgaaaatcctcgactttggactggccaggacggcaggcacgagcttcatgatg
actccttatgtggtcacacgttattatagagcccccgaggttattctgggaatgggctac
aaggagaatgtggatatatggtctgtgggatgcattatgggagaaatggttcgccacaaa
atcctctttccaggaagggactatattgaccagtggaacaaggtaattgagcaactagga
acaccatgtcctgaattcatgaagaaattgcaacctacagtaagaaactatgtggagaat
cggcccaagtatgcaggactcaccttccccaagctctttccagattccctcttcccagcg
gactctgagcacaataaactcaaagccagccaagccagggacttactgtcaaagatgcta
gtgatcgacccagcaaaaagaatatcggtggatgacgccttacagcatccttacatcaat
gtttggtatgaccctgccgaagtggaggcgcctccacctcagatttatgacaaacaattg
gatgaaagagaacacaccattgaagaatggaaagaacttatctacaaagaagtaatgaat
tcagaagaaaagactaaaaacggtgttgtaaaaggacaaccatctccttcaggtgcagca
gtgaacagcagtgagagtctccctccatcttcgtccgtcaatgacatctcctccatgtcc
accgaccagaccctggcatctgacactgacagcagcctggaagcttcagcaggacccctg
ggttgttgcaggtga

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