Mustela nigripes (black-footed ferret): 132002754
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Entry
132002754 CDS
T09425
Symbol
PDE5A
Name
(RefSeq) cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1
KO
K13762
cGMP-specific 3',5'-cyclic phosphodiesterase [EC:
3.1.4.35
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp00230
Purine metabolism
mnp01100
Metabolic pathways
mnp04022
cGMP-PKG signaling pathway
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
132002754 (PDE5A)
09130 Environmental Information Processing
09132 Signal transduction
04022 cGMP-PKG signaling pathway
132002754 (PDE5A)
Enzymes [BR:
mnp01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
132002754 (PDE5A)
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Motif
Pfam:
PDEase_I
GAF
GAF_2
HD-CE
DUF6970
Motif
Other DBs
NCBI-GeneID:
132002754
NCBI-ProteinID:
XP_059233849
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Position
1:complement(180514298..180662662)
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AA seq
865 aa
AA seq
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MERASPGSGGSQLQRDQDCVEAWLDDHWDFTFSYFVRKATREMVNAWFAERVHTIPVCKE
GIRSHTESCSCLSQPSPRADSSAPGTPTRKISASEFDRPLRPIVVKDSEGTVSFLADSEK
KEQMPLTPRRFDNDEGDQCSRLLELVKDISSHLDVTALCHKIFLHIHGLISADRYSLFLV
CEDSSNDKFLISRLFDVAEGSTLEEASNNCICLEWNKGIVGHVAAFGEPLNIKDAYEDPR
FNAEVDQITGYKTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDEKDFAAYLAFC
GIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQKCTIF
IVDEDCSDSFSSVFHMECEELEKSSDTLTRERDANRINYMYAQYVKNTMEPLNIPDVSKD
KRFPWTNENTGNINQQCIRSLLCTPIKNGKKNKVIGVCQLVNKMEENTGKVKPFNRNDEQ
FLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETRELQSLAAAVVPS
AQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNV
AYHNWRHAFNTAQCMFAALKAGKIQSKLTDLEILALLIAALSHDLDHRGVNNSYIQRSEH
PLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKMIKQAILATDLALYIK
RRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQG
DRERKELNIEPADLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCFPLLDGCRKNR
QKWQALAEQQEKMLINGESSQAKRN
NT seq
2598 nt
NT seq
+upstream
nt +downstream
nt
atggagcgggccagccccggttccggggggtcgcagctgcagcgggaccaggattgcgtg
gaagcgtggctggatgatcactgggactttaccttctcttactttgttaggaaagccacc
agagaaatggtcaatgcctggttcgctgagagagttcacacaatccccgtgtgcaaggaa
ggcattagaagccacacggaatcttgttcttgcctctcgcagccgagtcctcgtgcagac
agcagtgcgcctggtacaccaaccaggaaaatctctgcctctgaatttgatcggcctctt
agacccattgttgtcaaggattccgagggcactgtgagcttcctcgctgactcagaaaag
aaggaacagatgcctctaaccccccgaaggtttgataatgacgaaggggaccagtgctca
agactcttggaattagtgaaagatatttctagtcatttggatgtcacagccttatgtcac
aaaattttcttgcatattcatggacttatctccgccgatcgctattctctgtttctggtc
tgtgaggacagctccaatgacaagtttcttatcagccgtctgtttgatgttgcggaaggt
tcaacactggaagaagcttcaaataactgtatctgcttagaatggaacaaaggcattgtg
gggcacgtggcagcatttggtgagcccttgaacatcaaagatgcttatgaggatcctcgg
ttcaatgcagaagttgaccaaattacaggctacaagacacagagtattctttgtatgcca
attaagaatcacagggaagaggttgttggtgtagcccaggccatcaacaagaaatcagga
aatggtgggacattcactgaaaaagatgaaaaggactttgctgcttatttggcattttgt
ggtattgttcttcataatgctcaactctatgagacttcactgctggagaacaagagaaat
caggtgctgcttgaccttgctagcttaatttttgaagaacaacaatcattagaagtaatt
ctaaagaaaatagctgccactattatctctttcatgcaggtgcagaaatgcaccattttc
atagtggatgaagattgctccgattctttttctagtgtgtttcacatggagtgtgaggaa
ttagaaaaatcgtcagatactttaacaagggaacgtgatgcaaacagaatcaattacatg
tatgctcagtatgtcaaaaatactatggaaccacttaatatcccagatgtcagtaaggac
aaaagatttccctggacaaatgaaaacacaggaaatataaaccagcagtgcattagaagt
ttgctttgtacacctataaaaaatggaaagaagaataaagtgataggggtttgccaactt
gttaataagatggaggagaatactggcaaggttaagcctttcaaccgaaatgatgaacag
ttcctggaggcttttgtcatcttttgtggcttggggatccagaacacacagatgtatgaa
gcggtggagagagccatggccaagcaaatggtcacactggaggttctgtcgtatcatgct
tcagcagcagaggaagaaacaagagaactccagtccttagcggccgctgtggtaccatct
gctcagacacttaaaattactgacttcagcttcagtgactttgagctgtctgacctagaa
acggcactgtgcacaattcggatgttcactgacctcaaccttgtgcagaacttccagatg
aaacatgaggttctttgcaggtggattttaagtgttaagaagaattatcggaagaatgtt
gcctatcataattggagacacgcctttaatacagctcagtgcatgtttgctgctctaaaa
gcaggcaagattcagagcaagctgactgacctggagatccttgcgctgctcatcgcggct
ctcagccatgacttggaccaccggggtgtgaataactcttacatccagcgaagtgaacac
ccacttgctcagctctactgccattcaatcatggaacatcatcattttgaccagtgcctg
atgattcttaatagcccaggcaaccagatcctcagtggcctctccattgaagaatataaa
accacgctgaaaatgatcaagcaagctattttagctacagacctagcactgtacattaag
agacgaggagaattttttgaacttataagaaaaaatcaattcaacttagaagatcctcat
caaaaagaattgtttttagcgatgttgatgacagcttgcgatctctctgccattaccaaa
ccctggcctattcaacaacggatagcagaacttgtagcgactgaattttttgaccaagga
gacagagagagaaaagagctcaacatagagcctgctgatctaatgaacagggagaagaaa
aataaaattccaagtatgcaagttgggttcatagatgccatctgcttgcaactctatgag
gccctgacccatgtatcagaggactgtttccctttgctggatggctgcagaaaaaacagg
caaaaatggcaggctctcgcagaacagcaggagaaaatgctgattaatggggagagcagc
caggccaagcggaactga
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