Mustela nigripes (black-footed ferret): 132003912
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Entry
132003912 CDS
T09425
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp01521
EGFR tyrosine kinase inhibitor resistance
mnp01522
Endocrine resistance
mnp01524
Platinum drug resistance
mnp04010
MAPK signaling pathway
mnp04012
ErbB signaling pathway
mnp04020
Calcium signaling pathway
mnp04066
HIF-1 signaling pathway
mnp04151
PI3K-Akt signaling pathway
mnp04510
Focal adhesion
mnp04520
Adherens junction
mnp04530
Tight junction
mnp05200
Pathways in cancer
mnp05205
Proteoglycans in cancer
mnp05206
MicroRNAs in cancer
mnp05212
Pancreatic cancer
mnp05213
Endometrial cancer
mnp05215
Prostate cancer
mnp05219
Bladder cancer
mnp05223
Non-small cell lung cancer
mnp05224
Breast cancer
mnp05226
Gastric cancer
mnp05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
132003912 (ERBB2)
04012 ErbB signaling pathway
132003912 (ERBB2)
04066 HIF-1 signaling pathway
132003912 (ERBB2)
04020 Calcium signaling pathway
132003912 (ERBB2)
04151 PI3K-Akt signaling pathway
132003912 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
132003912 (ERBB2)
04520 Adherens junction
132003912 (ERBB2)
04530 Tight junction
132003912 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
132003912 (ERBB2)
05206 MicroRNAs in cancer
132003912 (ERBB2)
05205 Proteoglycans in cancer
132003912 (ERBB2)
05230 Central carbon metabolism in cancer
132003912 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
132003912 (ERBB2)
05226 Gastric cancer
132003912 (ERBB2)
05219 Bladder cancer
132003912 (ERBB2)
05215 Prostate cancer
132003912 (ERBB2)
05213 Endometrial cancer
132003912 (ERBB2)
05224 Breast cancer
132003912 (ERBB2)
05223 Non-small cell lung cancer
132003912 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
132003912 (ERBB2)
01524 Platinum drug resistance
132003912 (ERBB2)
01522 Endocrine resistance
132003912 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mnp01001
]
132003912 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mnp04147
]
132003912 (ERBB2)
04090 CD molecules [BR:
mnp04090
]
132003912 (ERBB2)
Enzymes [BR:
mnp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
132003912 (ERBB2)
Protein kinases [BR:
mnp01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
132003912 (ERBB2)
Exosome [BR:
mnp04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
132003912 (ERBB2)
CD molecules [BR:
mnp04090
]
Proteins
132003912 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
ABC1
Haspin_kinase
Bestrophin-like
Kinase-like
CcmD
Motif
Other DBs
NCBI-GeneID:
132003912
NCBI-ProteinID:
XP_059235795
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All DBs
Position
16:complement(21773213..21797438)
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AA seq
1260 aa
AA seq
DB search
MELAAWCRWGLLLALLPSGAVGTQVCTGTDMKLRLPASPETHLDMLRHLYQACQVVQGNL
ELTYLPANASLSFLQDIQEVQGYVLIAHSQVRQVPLQRLRIVRGTQLFEDHYALAVLDNG
DPPEGGPSVAGAAPGGLRELQLRSLTEILKGGVLIQRNPQLCHQDTILWKDIFHKNNQLA
LTLIDTNRSRACQPCSPACKDLHCWGASSGDCQSLTRTVCAGGCARCKGPKPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTSCP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSAN
IQEFAGCKKIFGSLAFLPESFEGDPASNTAPLQPEQLRVFEALEEITGYLYISAWPDSLP
DLSVFQNLRVIRGRVLHDGAYSLTLRGLGISSLGLRSLRELGSGLVLIHRNAHLCFIHTV
PWDQLFRNPHQALLHSANRPEAECVGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLQGLPREYVKDRYCLPCHSECRPQNGSVTCFGSEADQCVACAHYKDTPFCVARC
PSGVKPDLSFMPIWKFADEEGTCQPCPINCTHSCADLDERGCPAEQRASPVTSIIAAVVG
ILLAVLVGLVLGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGAGGPAHRRHRSSSTRSGGGELTLGLEPSEEEPPKSPRAPSEG
AGSDVFDGDLGMGAAKGLQSLPPQDTSPLQRYSEDPTAPLPPETDGYVAPLTCSPQPEYV
NQPEVWPQPPSPLEGPLPPPRPAGATLERPKTLSPKTLSPGKNGVAKDVFAFGSAVENPE
YLVPRGRAAPQPHPPPAFSPAFDNLYYWDQDPSERGSPPSTFEGTPTAENPEYLGLDVPV
NT seq
3783 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctgctcgccctcctgccctccggagcc
gtgggcacccaagtgtgcaccggcacagacatgaagctgcggctcccagccagtcccgag
acccacctggatatgctccgccacctctaccaggcctgtcaagtggtgcagggtaacctg
gagctcacctacctgcctgccaatgccagcctgtccttcctgcaggatatccaggaggtg
cagggctacgtgctcatcgctcacagccaagtgaggcaggtcccgctgcagaggctccga
attgtacggggcacccagctctttgaggaccactatgccctggccgtgctggacaatgga
gacccgcccgaggggggcccctctgtggcaggggctgccccaggagggctgcgggagctg
cagcttcgaagcctcacagagatcctgaagggcggggtcttgattcagcggaacccacag
ctctgccaccaggacacgatcctgtggaaggacatcttccacaagaacaaccagctggcc
ctcacgctaatagacaccaaccgctctcgggcctgccagccctgttctccagcttgtaaa
gacctccactgctggggagcaagttccggggactgtcagagcttgacgcgaaccgtctgt
gctggcggctgtgcccgctgcaagggcccgaaacccacggactgctgccacgagcagtgt
gcggctggctgcacgggccccaagcactcggactgcctggcctgccttcacttcaaccac
agtggcatctgtgagctacactgtccagccctggtcacctacaacacagacaccttcgaa
tccatgcccaaccctgagggccggtacaccttcggagccagctgtgtgacctcctgtccc
tacaattacctgtcaacggatgtgggatcctgcaccctggtctgtcccctgaacaaccaa
gaggtgacggctgaggatggaacgcagcgttgtgagaaatgcagcaagccctgtgcccga
gtgtgctacggcctgggcatggagcacctgcgggaggtgagggcggtcaccagcgccaac
atccaagagtttgccggctgcaagaagatctttgggagcctggcatttctgccagagagc
tttgagggagacccagcctccaacactgcccccctccagcctgagcagctcagagtgttt
gaggccttggaggagatcacaggttacctgtacatctcagcatggccagacagcctgcct
gacctcagtgtcttccagaacctgcgagtcatccggggacgagttctgcatgacggtgcc
tactcgctgaccctgcgagggctgggcatcagctctctggggctgcgctcgctgcgggaa
ctgggcagcgggctggtcctcatccaccgcaacgcccacctgtgcttcatacacacggtg
ccctgggaccagctcttccggaacccgcaccaggccctgctccacagcgccaaccggcca
gaggctgagtgtgtgggcgagggcctggcctgctacccgctgtgcgcccatgggcactgc
tggggtccggggcccacccagtgcgtcaactgcagccaattccttcggggccaggagtgc
gtggaggaatgccgagtactgcaggggctaccccgggagtatgtgaaggacaggtactgt
ctcccatgccactccgagtgtcggccgcagaacggctcagtaacctgctttgggtcggaa
gctgaccagtgtgtggcctgcgcccactacaaagacactcccttttgcgtggctcgctgc
cccagtggcgtgaaacccgacctctccttcatgcccatttggaagttcgccgatgaggag
ggcacgtgccagccatgccccatcaactgcacccactcctgtgcggatctggacgagagg
ggctgccccgccgagcagagagccagccctgtgacgtccatcattgccgctgtggtgggc
attctgctggccgtgcttgtggggctggtcctcggcatcctaatcaagcgaaggcggcag
aagatccgcaagtacacgatgcggaggctgctgcaggaaaccgagctggtggagccgctg
acgcccagcggagccatgcccaaccaggctcagatgcggatcctgaaagagacagaactg
aggaaggtgaaagtgcttggatccggagcctttggcactgtctacaagggcatctggatc
cctgatggggaaaatgtgaagattccagtggccattaaagtgttgagggaaaacacatct
cccaaagccaacaaagaaatcttggacgaagcatatgtgatggctggcgtgggctcccca
tatgtgtcccgccttctgggcatctgcctgacatccacggtgcagctggtgacacagctt
atgccctatggctgcctcttagaccacgtccgagagcatcgtgggcgcctgggctcccaa
gacctgctgaactggtgtgtgcagatcgccaaggggatgagctacttagaggatgttcgg
ctggtgcacagggacctggctgcccggaacgtgctggtcaagagtcccaaccatgtcaag
ataacagactttgggctggctcggctgctggacattgacgagaccgagtaccacgcagat
gggggcaaggtgcccatcaagtggatggcgctggagtccattctccgccggcggttcacc
caccagagtgacgtgtggagctacggtgtgactgtgtgggaactgatgacttttggggcc
aaaccttacgatgggatcccagcccgggagatccctgacctgctggaaaagggggaacgg
ctgccccagccccccatctgcaccattgacgtctacatgatcatggtcaaatgttggatg
atagactctgaatgtcgaccacggttccgggagttggtggccgaattctcccgcatggcc
agggacccccagcgcttcgtggtcatccagaatgaagacttgggccccgccagcccactg
gacagcaccttctaccgctcgctgctggaagatgatgacatgggggacctcgtggatgct
gaggagtacctggtgccccagcaggggttcttctgccccgaccctgccccaggtgctggg
ggcccagcccaccgcaggcaccgcagctcatccacgaggagtggcggtggtgagctgaca
ctgggactggagccctccgaggaggagccccccaagtctccacgggcaccctcagagggg
gctggctctgacgtgtttgatggcgacttgggaatgggggcagccaaggggctgcagagc
cttcccccacaggacaccagccctctacagcggtacagcgaagaccctactgcacccctg
cccccagagactgatggctacgttgcccccctgacctgcagcccccagcctgaatacgtg
aaccagccggaggtttggccgcagcccccctcacccctagaaggccctctgccaccgcct
cgacctgccggtgccactctggaaaggcccaagactctgtcccccaagactctctcccct
ggcaagaatggggttgccaaagacgtttttgcctttgggagtgctgtggagaaccctgag
tacttggtaccccggggcagggctgcccctcagccccaccctcctccagccttcagtcca
gcctttgacaacctctattactgggaccaggacccatcagagcggggctctccacccagc
acctttgaagggacccctacagcagagaaccctgagtacctgggcctggatgtgccagtg
tga
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