Mustela nigripes (black-footed ferret): 132005665
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Entry
132005665 CDS
T09425
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp00562
Inositol phosphate metabolism
mnp01100
Metabolic pathways
mnp01521
EGFR tyrosine kinase inhibitor resistance
mnp04012
ErbB signaling pathway
mnp04014
Ras signaling pathway
mnp04020
Calcium signaling pathway
mnp04062
Chemokine signaling pathway
mnp04064
NF-kappa B signaling pathway
mnp04066
HIF-1 signaling pathway
mnp04070
Phosphatidylinositol signaling system
mnp04072
Phospholipase D signaling pathway
mnp04360
Axon guidance
mnp04370
VEGF signaling pathway
mnp04380
Osteoclast differentiation
mnp04611
Platelet activation
mnp04613
Neutrophil extracellular trap formation
mnp04625
C-type lectin receptor signaling pathway
mnp04650
Natural killer cell mediated cytotoxicity
mnp04662
B cell receptor signaling pathway
mnp04664
Fc epsilon RI signaling pathway
mnp04666
Fc gamma R-mediated phagocytosis
mnp04670
Leukocyte transendothelial migration
mnp04722
Neurotrophin signaling pathway
mnp04750
Inflammatory mediator regulation of TRP channels
mnp04919
Thyroid hormone signaling pathway
mnp04933
AGE-RAGE signaling pathway in diabetic complications
mnp04935
Growth hormone synthesis, secretion and action
mnp05167
Kaposi sarcoma-associated herpesvirus infection
mnp05169
Epstein-Barr virus infection
mnp05170
Human immunodeficiency virus 1 infection
mnp05171
Coronavirus disease - COVID-19
mnp05200
Pathways in cancer
mnp05205
Proteoglycans in cancer
mnp05206
MicroRNAs in cancer
mnp05214
Glioma
mnp05223
Non-small cell lung cancer
mnp05225
Hepatocellular carcinoma
Module
mnp_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
132005665 (PLCG2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
132005665 (PLCG2)
04014 Ras signaling pathway
132005665 (PLCG2)
04370 VEGF signaling pathway
132005665 (PLCG2)
04064 NF-kappa B signaling pathway
132005665 (PLCG2)
04066 HIF-1 signaling pathway
132005665 (PLCG2)
04020 Calcium signaling pathway
132005665 (PLCG2)
04070 Phosphatidylinositol signaling system
132005665 (PLCG2)
04072 Phospholipase D signaling pathway
132005665 (PLCG2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
132005665 (PLCG2)
04613 Neutrophil extracellular trap formation
132005665 (PLCG2)
04625 C-type lectin receptor signaling pathway
132005665 (PLCG2)
04650 Natural killer cell mediated cytotoxicity
132005665 (PLCG2)
04662 B cell receptor signaling pathway
132005665 (PLCG2)
04664 Fc epsilon RI signaling pathway
132005665 (PLCG2)
04666 Fc gamma R-mediated phagocytosis
132005665 (PLCG2)
04670 Leukocyte transendothelial migration
132005665 (PLCG2)
04062 Chemokine signaling pathway
132005665 (PLCG2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
132005665 (PLCG2)
04919 Thyroid hormone signaling pathway
132005665 (PLCG2)
09156 Nervous system
04722 Neurotrophin signaling pathway
132005665 (PLCG2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
132005665 (PLCG2)
09158 Development and regeneration
04360 Axon guidance
132005665 (PLCG2)
04380 Osteoclast differentiation
132005665 (PLCG2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
132005665 (PLCG2)
05206 MicroRNAs in cancer
132005665 (PLCG2)
05205 Proteoglycans in cancer
132005665 (PLCG2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
132005665 (PLCG2)
05214 Glioma
132005665 (PLCG2)
05223 Non-small cell lung cancer
132005665 (PLCG2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
132005665 (PLCG2)
05171 Coronavirus disease - COVID-19
132005665 (PLCG2)
05167 Kaposi sarcoma-associated herpesvirus infection
132005665 (PLCG2)
05169 Epstein-Barr virus infection
132005665 (PLCG2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
132005665 (PLCG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
132005665 (PLCG2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mnp04131
]
132005665 (PLCG2)
Enzymes [BR:
mnp01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
132005665 (PLCG2)
Membrane trafficking [BR:
mnp04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
132005665 (PLCG2)
Endocytosis
Macropinocytosis
Phospholipase C
132005665 (PLCG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
C2
SH3_1
PH
SH3_9
PH_12
SH2_1
SH3_2
PH_14
GDPD
EF-hand_like
Motif
Other DBs
NCBI-GeneID:
132005665
NCBI-ProteinID:
XP_059239046
LinkDB
All DBs
Position
17:53495448..53642207
Genome browser
AA seq
1265 aa
AA seq
DB search
MTAPANVDTLPEHEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADK
IEGFLDIMEIKEIRPGKNSKDFERAKVVHQKKDCCFTIFYGTQFVLSTLSLAADSKEDAS
KWLSGLKILHQEAMSASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLVNFKVSSA
KFLKDKFVEIGAHKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASA
VYLHDFQRFLLHEQQELWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENS
IWDEKYDVVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRAGCRCIELDC
WDGPDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCCVEQQRHMARV
FKEVFGDQLLTKPTEASADQLPSPSQLREKFIIKHKKLGPRGDVDVNMEDKKDEHKQQGE
LYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTAEEELPQDIPPTELHFGEEWFHKKVEKR
TSAERLLQEYCAETGGKDGTFLVRESKTFPNDYTLSFWRSGRVQHCRIRSTMEGGTMKYF
LTDNVTFTSIYDLIQHYRETHLRCTEFELRLTDPVPNPNPHESKPWYYDGLSRGEAEDML
MRVPRDGAFLIRRREGTDSYAITFRARGKVKHCRIHRDGRHFVLGTSAYFESLVELVSYY
EKHALYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEISPSMPQRTVKALYDY
KAKRNDELSFCRGALIHNVSKEPWGWWRGDYGTRIQQYFPSNYVEDISTADVEELEKQII
EDNPLGSLCRGILDLNTYNVVKAPHGKNQKQFVFILEPKKQGDPPVEFATDKVEELFEWF
QSIREITWKMDTKENSMKYWEKNQSIAIELSDLVVYCKPTSKAKDNLENPDFREIRSFVE
TKADSVVRQKPVDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTPDKY
MQMNHALFSLNGRTGYVLQPESMRSEQYDPMPPENQRKILMTLSVKVLGARHLPKLGRSI
ACPFVEVEICGAEYDNNKFKTTVVNDNGLSPIWAPTQEKVTFEIYDPNLAFLRFVVYEED
MFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMQPVLESEEELYSSC
RQLRRRQEELNNQLFLYDTHQNLRNANRDALVKEFNVNENQLQLYQEKCNRRLREKRVSN
SRFYS
NT seq
3798 nt
NT seq
+upstream
nt +downstream
nt
atgaccgccccggccaacgtggacaccctccccgagcacgaaaagagtcagatcaagagg
gcgctggagctgggcacggtgatgacggtgttcagcttccgcaagtccaccccggagcgg
aggaccgtccaagtcatcatggagacccgccaggtggcctggagcaagaccgccgacaag
atcgagggtttcttggatatcatggaaatcaaggaaatccgccccgggaagaactccaag
gattttgagcgtgcaaaggttgtgcatcagaagaaagactgctgcttcaccatcttctac
gggacccagttcgtcctcagcaccctcagcctggcagccgactccaaggaggatgcgagt
aagtggctctcgggcttgaaaatccttcaccaggaagcgatgagcgcgtctacacccacc
atcattgagagctggctgagaaagcagatctattcagtggatcaaaccagaagaaacagc
atcagcctccgagagttgaagaccatcttacccctggtcaacttcaaagtgagcagtgcc
aagttcctcaaagacaagtttgtggaaattggtgcacacaaagatgaactcagctttgag
cagttccacctgttctataaaaaacttatgtttgagcagcaaaagtcgattcttgatgaa
ttcaaaaaagattcttctgtgttcatcttgggcaacaccgaccggccggacgcctctgcg
gtttacctgcacgacttccagcgctttctcttacacgagcagcaggagctttgggctcag
gatctgaacaaagtccgagagcggatgactaagttcatcgatgacaccatgagggagact
gccgagcccttcttgtttgtcgatgagttcctcacgtacctcttttcgcgggagaacagc
atctgggatgagaagtacgacgtggtggacatgcaggacatgaacaaccccttgtcccat
tactggatctcctcttcgcataacacgtacctcaccggcgaccagctgcggagcgagtcg
tccacagaagcctacatccgctgcctgcgggcgggctgccgctgcattgagctggactgc
tgggatgggcccgacgggaagcccatcatctaccatggctggacacggaccaccaagatc
aagtttgatgacgtcgtgcaggccatcaaagaccatgcctttgtcacctccagcttccca
gtgatcctgtccatcgaggagcactgttgcgtggagcagcagcgccacatggcccgggtg
ttcaaggaggtgtttggcgaccagctgctgacgaagcccacggaggccagcgctgaccag
ctgccctcacccagccagctgcgggagaagttcatcatcaagcataagaagctgggtccc
cggggcgacgtggatgtcaacatggaggacaagaaggatgagcacaagcagcagggtgaa
ctgtacatgtgggattccatcgaccagaaatggactcggcactactgtgccatcgccgat
gccaagctgtcgttcagcgacgacattgaacagacagcagaagaggagctgccccaggat
ataccccccacagagctgcattttggggaggagtggttccacaagaaggtggagaagagg
acgagtgccgagaggctgctgcaggagtactgtgcggagacggggggcaaagacgggacc
ttcctggtgcgagagagcaagaccttccccaacgactacaccctgtccttctggcggtct
ggccgggtccagcactgccggatccggtccaccatggagggtgggaccatgaagtacttc
ctgaccgacaacgtcacgttcaccagcatctatgacctcatccagcattaccgcgagacg
cacctgcgctgcaccgagttcgagctccggctcaccgaccccgtgcccaaccccaacccc
cacgagtcaaagccgtggtactacgacgggctgagccgcggggaagcggaggacatgcta
atgagggttccccgggacggcgccttcctcatccggaggcgagaaggcaccgactcgtac
gccatcaccttcagggccaggggcaaggtcaagcactgccgcatccaccgggacggccgg
cacttcgtgctggggacctcggcctacttcgagagcctcgtggagctcgtgagctactac
gagaagcacgcgctgtaccggaagatgcggctgcgctaccccgtgacgccggagctcctg
gagcgctacaacatggaaagagacataaactccctttacgacgtcagcagaatgtatgtg
gatcccagtgaaatcagcccctccatgcctcagagaactgtgaaagctctgtatgactac
aaagccaagcggaacgatgagttgagcttctgccgtggggccctcattcacaacgtctcc
aaggagccctggggctggtggagaggggactatggaaccagaatccagcagtacttcccg
tccaattacgtcgaggacatttcaacagccgacgtggaggagctggagaagcagattatt
gaggacaatcccttagggtctctctgtcggggaatattggatctcaacacctataacgtg
gtgaaagcgccccacgggaagaaccagaagcagttcgtgttcatcctggagcccaagaag
caaggtgacccgccggtggagttcgccacggacaaggtggaggagctcttcgagtggttt
cagagtatccgagagatcacgtggaagatggacaccaaggagaacagcatgaagtactgg
gagaagaaccagtccatcgccatcgagctctcagacctggtcgtctactgcaagccaacc
agcaaggccaaggacaatctcgaaaaccccgacttccgagaaatccgctcctttgtggag
acgaaggcggacagtgtcgtcaggcagaaacctgtcgacctcctgaagtacaaccagaaa
ggcctgactcgagtttaccccaagggacagagggtggactcctccaactacgaccccttt
cgcctctggctgtgcggctcccagatggtggctctcaatttccagactccagataagtac
atgcagatgaaccatgccttgttctcactcaatggtcgcacgggctacgtcctccagccc
gagagcatgaggtccgagcagtacgacccgatgcctcccgagaaccagagaaagatcttg
atgaccctgtcggtcaaggttctcggggctcgccatctccccaaacttggacgaagtatt
gcgtgtccctttgtggaggtggaaatttgtggagctgagtatgacaacaacaagtttaag
acaacagttgtgaatgacaatggcctcagcccgatttgggctccaacacaggagaaagtg
acctttgaaatttatgaccccaacctggcgtttctgcgttttgtcgtctacgaggaagat
atgttcagtgatcccaacttccttgcccacgccacttaccccatcaaaggaatcaaatcg
ggattcagatctgttcctctgaagaacgggtacagtgaagacatcgagctggcttccctc
ctggttttctgtgagatgcagccagtcctggagagcgaagaggagctctactcctcctgc
cgccagctgcgaaggcggcaggaagagctaaacaatcagctctttctgtacgacacgcac
cagaacttgcgcaatgccaaccgtgacgccctcgttaaggagttcaatgtcaacgagaac
cagctccagctgtaccaggagaagtgcaaccggaggttgcgagagaagagagtcagcaac
agcaggttttactcctag
DBGET
integrated database retrieval system
