Mustela nigripes (black-footed ferret): 132009576
Help
Entry
132009576 CDS
T09425
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp00310
Lysine degradation
mnp01100
Metabolic pathways
mnp05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
132009576 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
132009576 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mnp03036
]
132009576 (DOT1L)
Enzymes [BR:
mnp01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
132009576 (DOT1L)
Chromosome and associated proteins [BR:
mnp03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
132009576 (DOT1L)
HMT complexes
Dot1-containing complex
132009576 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
132009576
NCBI-ProteinID:
XP_059243598
LinkDB
All DBs
Position
2:1346764..1404416
Genome browser
AA seq
1692 aa
AA seq
DB search
GAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVLIDYDTKSFESMQR
LCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVTDPEKLNNYEPFSP
EVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCKHHYGVEKADIPAK
YAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFVNNFAFGPEVDHQL
KERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLKGSVSWTGKPVSYY
LHTIDRTILENYFSSLKNPKLREEQEAARRRQQRESKSATTTPTKGPESKAAASADAPTD
SGAEEEKAGATTIKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSTANPERKPKKSQTAL
DLLHAQAAPQTAAPSPQDAYKSPQSPFYQLPPSVQRHPPDQLLLAPTPPALQKLLESFKI
QYLQFLAYTKTAQYKASLQQLLDQEKEKNARLLGAAQQLFGHCQAQKEEIKRLFQQKLDE
LGVKALTYNDLIQAQKEISAHNQQLREQTEQLQKDNGELRTQSLRLLKARCEELKLDWST
LSLENLLKEKQALRTQISEKQRHCLELQISIVELEKSQRRQELLQLKSCVPPDDGLSAHL
RGKGALGRELEAEPGRLHLDLDGPKFSLPHLSSASPELSMNGHVAGYEVCGALSRPSSKQ
NTPQYLASPLDQDVVPCTPSHGGRPRLEKMAGLALPDYTRLSPAKLVLRRHLSQDHAAGG
KPAAGELHPRAEHAKENGLPYQSPGIANGIKLSPQDPRPSSPAALQMTGERGSEKGVKER
AYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKVRSTPSPVSQTRESSST
LEKQMGANAHGAGSKNLAPASTGFYTGSGAVSGALAGSPAPLAPGAEPGTLDEVSSSGSL
FAGMGSCGSAPQLPPLLQQSRSSGAASPAHPLCASPRLSSAAQGPLPEANKGDLPSEAGI
SDPEGEVKRRIVFTISAGGGAKQSPPGKPSPLPAGARGDSGQGHGPDSRKRGRRKRAAAG
TPSLSSGVSPKRRALPSVAGLFTQSSGSPLNLNSMVSNINQPLEITAISSPESLKSSPVP
YQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEEQGSEDEPGSARIERKIATISLESKSPPK
TLESGGGLTGRKPAPASEPANSSKWKSTFSPISDLGLAKCADSPLQASSALSQNSLFAFR
PPLEEPGLADAKLAAHPRKGFPGALAGAGGLSPSSNPPNGFAFSGGLTADLSLHSFSDGA
SLSHKVPETASLSGPLSFPTPRGKEGAAAEPGTFVNKRQLDGLSGPKAREAGEPGLPACG
PPDKASLTHSKPGKGRDREPDLKNGHNLFISAATVPPGGLLSGPGLATVASSTVSAAPSA
QTHRPFLGTFAPGPQFALGPMSLQANLGSSVLQSLFSSVPAAAGLVHVSSAATRLTNSHA
MGSFSSGVAGGAVGGVFNHAVPSASAHPFGASFGSGAACRSGTPGVTALQAAGAPASSFQ
APPPPPQGRPALPAPAPPNAALPPAPALLPANSEPVLLQNLASLPANQAFLPAASAASLQ
PANASLSIQLTSLPHKAPRPSFTVHHQPLPGLALAQAAPVIPQAGSTGPSAVWVSLGMPP
PYAARLAGVKPR
NT seq
5079 nt
NT seq
+upstream
nt +downstream
nt
ggggccgagcccgccgtctacccgtggccgctgccggtctacgacaaacaccacgatgct
gctcacgaaatcatcgagaccatccggtgggtctgtgaggagatcccggacctcaagctt
gctatggagaattacgttctcatcgactacgacaccaaaagcttcgaaagcatgcagagg
ctctgtgacaagtacaaccgcgccatcgacagcatccaccagctgtggaaggggaccacg
cagcccatgaagctgaacacgcggccgtccaacgggctcctgcggcacatcctgcagcag
gtctacaaccactcggtgacggaccccgagaagctcaacaactacgagcccttctccccg
gaggtgtacggggagacgtcctttgacttggtcgctcagatgatcgacgagatcaagatg
actgaggacgacctgtttgtggacctgggcagtggagtgggccaggtcgtgctacaggtc
gccgcggccaccaactgtaagcatcactacggcgtggagaaagcggacatcccagccaag
tacgcggagaccatggaccgagagttcaggaagtggatgaaatggtatggaaaaaagcat
gcagaatacacactggagagaggcgacttcctctcagaggagtggagagagcggatcgcc
aacacaagtgttatatttgtgaataactttgcctttggtcctgaggtggatcaccagctg
aaggagcggtttgccaacatgaaggaaggtggcagaatcgtgtcctcgaagcccttcgca
cctctgaactttagaataaacagcaggaacttgagcgacatcggcaccatcatgcgggtc
gtagagctctcgcccctgaagggctcagtgtcctggacggggaagccggtctcctactat
ctgcacaccatcgaccgcaccatacttgaaaactatttttctagtctgaaaaatccaaaa
ctcagggaggagcaagaggcagctcggcggcggcaacagcgggaaagcaagagcgccacg
accactcccaccaaggggcccgagagcaaggctgccgcgtctgcggatgccccgacggat
tcgggggccgaggaagaaaaagctggggcaaccaccatcaaaaagccgtccccctccaaa
gcccggaaaaagaagctgaacaagaaggggcggaagatggccggccggaagcgcgggcgc
cccaagaagatgagcactgcgaaccccgagcgtaagcccaagaagagccaaaccgcactg
gacctcctgcacgcccaggccgcgccgcagacggcagcgccctcgccgcaggacgcgtac
aagtcacctcagagcccgttttaccagctacctcccagcgtgcagcggcacccccccgac
cagctgctgctggctcccaccccgcccgcactgcagaagctgctagagtccttcaagatt
cagtacttgcagttcttggcctacaccaagaccgcccagtataaggccagcctgcagcag
ctgctggaccaggagaaggagaagaacgcccggttgctgggcgccgcgcagcagctattt
ggccactgccaggcccagaaggaggagatcaagaggctcttccagcagaagctggacgag
ctgggagtgaaggcgctgacctacaacgacctgatccaggcgcagaaggagatctcggcc
cacaaccagcagctgcgggagcagacggagcagctgcagaaggacaacggggagctgagg
acgcagagcctgcggctgctcaaggctcggtgtgaggagctgaagctggactggtccacg
ctgtccctggagaacctgctgaaggagaagcaggccctgaggacccagatctccgagaag
cagaggcactgtctggagctgcagatcagcatcgtggagctggagaagagccagcggcgg
caggagctcctgcagctgaagtcgtgcgtgccgcccgacgacggcctgtccgcacacctg
cgtgggaagggcgccctgggccgggagctggaggctgagcctggccgtctgcacctcgac
ctggacggccccaagttctcactgccccacttgagcagcgccagcccggagctctccatg
aacggccacgtggccggctatgaggtgtgcggtgcgctgagccggccctcgtccaagcag
aacacgccccagtacctggcctccccgctggaccaggacgtcgtgccctgtactcccagc
cacggtggtcggccacggcttgagaagatggcaggcctggccttgcccgactatacccgg
ctctccccggccaagctggtactcaggcggcacctgagccaggaccatgcagccggcggc
aagcctgcggccggcgagctacacccacgagctgagcacgccaaggagaacggccttcca
taccagagccctggcatcgccaacggtatcaagctgagccctcaggacccgcgaccgtcc
tcccccgccgccttacagatgacaggggagaggggcagcgagaagggtgtgaaggagcgc
gcctacgccagcagcggggaggccatcaccagcctgcccgtcagcatcccgctcagcacc
gtgcagcccagcaaactgcccgtcagcatccccctggccagcgtggtgctgcccagccgc
gccgagaaggtgagaagcacccccagccctgtgtcacagacccgagagtcctcgtccaca
cttgaaaagcagatgggcgctaatgcccacggcgctggaagcaaaaacctcgctccagct
tctacaggcttctacacgggctccggggccgtcagtggggccctggcaggcagcccggct
cccctcgctcccggagccgagcccggcaccttggatgaggtctcgagctcaggaagcctg
ttcgctggcatggggtcctgtggctccgccccgcagctcccgcccctgctccagcagtcc
cgcagctccggtgcggcctctcctgcccatccgctctgcgccagcccgcggctcagcagc
gctgcccagggcccgctgcccgaggccaacaaaggggaccttccctctgaggcaggcatc
tccgaccccgagggcgaggtcaagaggaggatcgtctttaccatctcggctggcggcggt
gccaaacagtcgcctcctggcaaacccagccctctgcccgcgggcgcccgtggggacagc
ggccaaggccatgggccggacagccgtaagcggggcaggaggaagcgggcggcggccggg
acccccagcctgagttccggcgtgtcgcccaagcgtcgggcactgccgtccgtcgccggc
ctcttcacacagtcttcagggtccccgctgaacctcaactcgatggtcagcaacattaac
cagcctttggaaatcacggccatctcgtcccctgagagcctgaagagctcccctgtccct
taccaggacaacgaccagccacccgttctcaagaaggagaagcccttgagccagaccaac
ggggcccactactccccactgacctcagacgaggagcagggctccgaggacgagccgggc
agcgccagaattgagaggaaaattgcaaccatctccttagaaagcaaatctcctccgaaa
accttggaaagcggtggtggcctgaccgggaggaagccggcgcctgccagcgagcccgcc
aacagcagcaagtggaaatccaccttctcacccatctccgaccttggcctggccaagtgc
gccgacagcccgctgcaggccagctccgccctgagccagaactccctgttcgctttccgg
ccgcccctggaggagcctggcctggccgatgccaagctggctgcccacccgaggaagggc
tttcccggtgccctggcgggggccgggggactgagccccagcagcaaccctcccaacggc
ttcgccttcagcgggggcctgaccgccgacctcagtttacacagcttcagcgatggtgct
tctctctcccacaaggtcccggagacggccagcctgagcggccccctgagttttcccacc
ccgcggggcaaggagggtgccgccgcagagcctggcacctttgtgaacaagaggcagctg
gacggactgagtggccccaaggccagagaggcgggcgagccgggcctcccggcgtgtggg
cctccagacaaggcctcgctgacgcacagcaagccgggcaagggccgggaccgcgagccc
gacttgaagaacggtcacaacctcttcatttctgccgccactgtgcctcccgggggcctt
ctcagcggcccgggccttgccacagtggcgtcctcgacggtcagcgcggctccctctgcc
cagacacaccgccccttcctgggcacctttgcccccggcccacagttcgccctgggtccc
atgtccctgcaggccaacctgggctcctccgtgctgcagtccctgttcagctctgtgccg
gccgccgccggcctggtgcacgtctcgtccgccgcgaccagactgaccaactcgcacgcc
atgggcagcttctcctctggggtggcaggcggcgcagttggaggtgtctttaaccacgcg
gtgccttccgcctccgcccatccgtttggagccagtttcggcagcggggccgcgtgtcgc
agcggcacgccgggcgtaaccgcgctgcaggcggccggcgcccccgcctcttcctttcag
gccccgcccccgcccccgcaggggcggcccgccctccccgcacccgcaccccctaacgct
gccttgcctcctgcccctgcgctgctcccggctaactctgagcccgtgcttctgcagaac
ctcgcgtccctcccggctaaccaggctttcttacccgccgcctctgccgcctctctgcag
cctgctaacgcctctctgtccatccagctcacctccctcccgcacaaggccccccgcccc
tccttcacggtgcaccaccagcccctgcccgggctggccctggcccaggctgcgcccgtg
atcccgcaggccggctccacggggccgtctgccgtgtgggtttcccttggcatgccgcct
ccgtatgccgcgcgccttgcgggggttaagccgagataa
DBGET
integrated database retrieval system
