Mustela nigripes (black-footed ferret): 132010973
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Entry
132010973 CDS
T09425
Symbol
PDE4A
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X1
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp00230
Purine metabolism
mnp01100
Metabolic pathways
mnp04024
cAMP signaling pathway
mnp04928
Parathyroid hormone synthesis, secretion and action
mnp05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
132010973 (PDE4A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
132010973 (PDE4A)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
132010973 (PDE4A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
132010973 (PDE4A)
Enzymes [BR:
mnp01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
132010973 (PDE4A)
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GFIT
Motif
Pfam:
PDEase_I
PDE4_UCR
Motif
Other DBs
NCBI-GeneID:
132010973
NCBI-ProteinID:
XP_059244975
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Position
2:7644194..7695831
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AA seq
871 aa
AA seq
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MEPPAAPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAEPERS
PHRPIERADAVDTGDRPGLRTSRMSWPSSFHGTGTGSGGASGGSCRRFEAENGPSPSPGR
SPLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTP
FAQVLASLRSVRSNFSLLTNVPIPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDW
CLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEI
SSPTMKDREKQPAPRQRPSQQPPPPGTQFQPMSQITGVKKLRHSSSLNDSSIPRFGVKTD
QEELLAQELENLNKWGLNIFCVSEYAGGRSLSCIMYTIFQERDLLKKFRIPVDTMVTYML
TLEDHYHPDVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGV
SNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEENCDIFQNLSKRQRQSLRKMVIDM
VLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLE
LYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL
VHPDAQEILDTLEDNRDWYYSAIRQSPSPPPDEEPRGPGHPPPPDKFQFELTLEEEEEEE
VSTAPGAFEVRDLTMAQDPSPAEEPWEVDGHVLPTEVKVEEPGVTQQGDTAHSVATGEDG
AMSPDASVEAGGRSSPLALSTESPPLPSLRTPPSPEEAPGLQGLPSVAAEVGAQKEHQAA
KRACSACTGTSGEEPTPLPAPGGWGSAGGPT
NT seq
2616 nt
NT seq
+upstream
nt +downstream
nt
atggagcccccggccgccccctcggagaggagcctgtctctgtctctgcccgggccccgg
gagggccaggccaccctgaagccgcccccccagcacctgtggcggcagccgcggaccccc
attcgtatccagcagcgcggctactccgacagcgcggagcgcgcagagcccgagcggtcg
ccacaccggcccatagagcgcgccgacgccgtggacaccggcgaccggcccggcctgcgc
acttcccgcatgtcctggccctcgtccttccacggtaccggcaccggcagcggcggcgcg
agcggaggcagctgcaggcgctttgaggcagagaatgggccctcgccgtctcccggccgc
agccccctggactcgcaggcgagcccgggcctcgtgctgcatgctggggccgccaccagc
cagcgccgggagtccttcctgtaccgctcagacagcgactacgacatgtcccccaaaact
atgtcccggaactcgtcggtcaccagcgaggcgcacgctgaggacctcattgtgacacct
tttgcccaggtgctggccagtctccggagtgttcgcagcaacttctcactcctgaccaat
gtacccattcccagcaacaaacggtccccattgggcggcccaaccccagtctgcaaggcc
acgctatcagaagagacatgtcagcaactggcccgggagacactggaggagctggactgg
tgtctcgaacagctggagaccatgcagacataccgctccgtgagcgagatggcttctcac
aagttcaagaggatgttaaaccgagaactcacacacctgtcagagatgagcaggtcagga
aaccaggtctctgagtacatctccaccacattcctggacaagcagaatgaagtggagatc
tcatcgcccacaatgaaggatcgagaaaaacagccagccccacggcagagaccctcccag
cagcccccgccccccgggacacagttccagcccatgtctcagatcacaggggtgaagaag
ttgagacacagcagcagcctgaatgattccagcatcccccgctttggggtaaagaccgac
caagaggagctcctggcccaagaactggagaacctgaacaagtggggcctgaacatcttt
tgcgtgtcggaatacgcgggcggccgctccctcagctgcatcatgtacacgatatttcag
gagcgggacttgctaaagaagtttcgcatcccagtggacaccatggtgacctacatgctg
accctggaggaccactaccaccccgacgtggcctaccacaacagcctgcacgcggctgat
gtgctgcagtccacacacgtgctgctggccacgcccgcgctcgatgctgtgtttacggac
ctggagattcttgccgccctctttgcagctgccattcatgacgtggaccaccctggggtc
tccaaccagttcctcatcaacaccaattcggagctggcgctcatgtacaacgacgagtcg
gtgctggagaaccaccacctggccgtgggcttcaagctgctgcaggaagagaactgcgac
atcttccagaatctcagcaagcgccagcggcagagcctgcgcaagatggtcatcgacatg
gtgctggccacggacatgtccaaacacatgaccctcctggctgacctgaagaccatggtg
gagaccaagaaagtgaccagctcgggtgtcctcctgctggacaactactccgaccgcatc
caggtccttcgcaacatggtgcactgtgccgacctcagcaaccccaccaaaccactggag
ctgtaccgacagtggacggaccgcatcatggccgagttcttccagcagggtgaccgggag
cgggagcggggcatggagatcagccctatgtgtgacaagcacacagcctcggtggagaag
tctcaggtgggtttcattgactatattgtacacccgctgtgggagacgtgggctgacctg
gtccacccagatgcgcaggagatcctggacacgttggaggacaatcgggactggtactac
agcgccattcggcagagcccttccccgccacctgacgaggagcccagagggccaggccac
ccacccccaccggacaagttccagtttgagctgactctggaggaggaagaggaagaggag
gtgtctaccgccccaggtgcatttgaagttcgggacttgaccatggctcaggatccatcc
ccggctgaggaaccgtgggaggtggatggccacgtcctgcccacagaggtgaaggtagag
gaacctggcgtcacacagcaaggcgacacagcacatagtgtggctacgggcgaggacggg
gccatgtccccagacgcatccgtggaggctgggggccgcagcagccccctggccctgtcc
actgagagcccccctctgccttccttgaggaccccaccctctccagaggaagccccgggc
ctccagggcctcccctccgtggcggccgaggtgggggcccaaaaagagcaccaggctgcc
aagagggcgtgcagtgcctgcacgggaacatctggcgaggagcccaccccactcccagct
cctggtgggtgggggtcagctggaggtcctacctga
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