Mustela nigripes (black-footed ferret): 132011454
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Entry
132011454 CDS
T09425
Symbol
PDHB
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit beta, mitochondrial
KO
K00162
pyruvate dehydrogenase E1 component subunit beta [EC:
1.2.4.1
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp00010
Glycolysis / Gluconeogenesis
mnp00020
Citrate cycle (TCA cycle)
mnp00620
Pyruvate metabolism
mnp00785
Lipoic acid metabolism
mnp01100
Metabolic pathways
mnp01200
Carbon metabolism
mnp01210
2-Oxocarboxylic acid metabolism
mnp04066
HIF-1 signaling pathway
mnp04922
Glucagon signaling pathway
mnp05230
Central carbon metabolism in cancer
mnp05415
Diabetic cardiomyopathy
Module
mnp_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
132011454 (PDHB)
00020 Citrate cycle (TCA cycle)
132011454 (PDHB)
00620 Pyruvate metabolism
132011454 (PDHB)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
132011454 (PDHB)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
132011454 (PDHB)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
132011454 (PDHB)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
132011454 (PDHB)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
132011454 (PDHB)
Enzymes [BR:
mnp01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
132011454 (PDHB)
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Motif
Pfam:
Transket_pyr
Transketolase_C
Motif
Other DBs
NCBI-GeneID:
132011454
NCBI-ProteinID:
XP_059246040
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Position
2:complement(26745311..26751031)
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AA seq
359 aa
AA seq
DB search
MAAVSGLMRRPLEQVSGLLRRRFHRTAPAALQVTVRDAINQGMDEELERDEKVFLLGEEV
AQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAI
DQVINSAAKTYYMSGGLQPVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNS
EDAKGLIKSAIRDNNPVVVLENELMYGVPFELPSEAQSKDFLIPIGKAKIERQGTHITVV
AHSRPVGHCLEAATVLSKEGIECEVINMRTIRPMDIETIEASVMKTNHLVTVEGGWPQFG
VGAEVCARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTLNI
NT seq
1080 nt
NT seq
+upstream
nt +downstream
nt
atggcggcagtgtctggcctgatgcggagaccccttgaacaggtctccgggctgctgagg
aggcgcttccaccggacggcgccggcggcgctgcaggtgacagttcgtgatgctataaac
caaggtatggatgaggagctggaaagagatgagaaggtatttctgcttggggaagaagtt
gcccagtatgatggggcatataaggttagtcgaggcctgtggaagaaatacggagataag
aggatcatagacactcccatatctgaaatgggctttgctggaattgctgtgggtgcagct
atggctgggttgaggcccatttgtgaatttatgaccttcaatttctctatgcaagccatt
gaccaggttataaactcagctgccaagacctactacatgtcggggggccttcagcctgtg
cccatagtcttcagggggcccaatggtgcctcagcaggagtggctgcccagcactcacag
tgctttgctgcctggtatgggcactgcccaggcctaaaggtcgtcagcccctggaattca
gaggatgcaaaaggacttattaaatcagccattcgggataataatccagtggtggtgcta
gagaatgaattgatgtatggagttccttttgaattaccctcagaagctcagtcaaaagat
tttctgattcccattggaaaagccaaaatagaaagacaagggacacacataaccgtagtt
gcccattcaagacctgtgggccactgcttagaagctgcaacagtgctatccaaagaggga
attgaatgtgaggtgataaatatgcgaaccatcagaccaatggacattgaaacaatagaa
gccagtgtcatgaagaccaatcatcttgtaactgtggaaggaggctggccacagtttgga
gtaggagctgaagtttgtgccaggatcatggaaggccctgcattcaatttcctggatgct
cctgcagttcgtgtcactggtgctgacgtccccatgccttatgcaaagattctagaagac
aactctatacctcaggttaaagacatcatatttgcaataaagaaaacattaaatatttag
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