KEGG   Mustela nigripes (black-footed ferret): 132011553
Entry
132011553         CDS       T09425                                 
Symbol
VHL
Name
(RefSeq) von Hippel-Lindau disease tumor suppressor isoform X1
  KO
K03871  von Hippel-Lindau disease tumor supressor
Organism
mnp  Mustela nigripes (black-footed ferret)
Pathway
mnp04066  HIF-1 signaling pathway
mnp04120  Ubiquitin mediated proteolysis
mnp05200  Pathways in cancer
mnp05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:mnp00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    132011553 (VHL)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    132011553 (VHL)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    132011553 (VHL)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    132011553 (VHL)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:mnp04121]
    132011553 (VHL)
Ubiquitin system [BR:mnp04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul2 complex
    Target recognizing subunit
     132011553 (VHL)
SSDB
Motif
Pfam: VHL VHL_C Arm_vescicular
Other DBs
NCBI-GeneID: 132011553
NCBI-ProteinID: XP_059246299
LinkDB
Position
2:51738840..51746703
AA seq 219 aa
MPRKAGNVEEAEAGAEEVGAEEVGPEEDGGEESGAEESGPEESDLEEPGAQEEMEAVQPR
PVLRSVNSCEPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHSYRGHLWLFR
DAGTYDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKERCLQVVRSLVKPENYRRLDI
VRSLYEDLEDHPNVRKDLERLTQEHFENQRLEGETEDFK
NT seq 660 nt   +upstreamnt  +downstreamnt
atgccccggaaggcagggaacgtggaagaggccgaggcgggtgcggaggaggtgggcgcc
gaggaggtgggtcctgaagaggacggcggggaggagtcgggcgcggaggagtccgggccg
gaagagtctgatctggaggagccgggcgcccaggaggagatggaggccgtgcagccgcgt
ccggtgctgcgctcggtgaactcctgcgagccgtcgcaggtcatcttctgcaaccgtagc
ccgcgcgtcgtgctgccggtgtggctcaacttcgacggcgagccgcagccctacccgacg
ctgccgccgggcacgggccgccgcatccacagctaccgaggtcacctttggctcttcaga
gatgcagggacatatgatggccttctggttaaccagactgagctctttgtgccatctctc
aatgttgatggacagcctatttttgccaacatcacactgccagtgtatacgctgaaagaa
cggtgcctccaggttgtccgaagcctagtcaagcccgagaattacaggagactggacatc
gtgagatcactctatgaagatctggaggaccacccgaatgtaaggaaagacctggagcgg
ctgacacaggagcattttgaaaatcaacggctggaaggggagactgaggattttaagtga

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