Mustela nigripes (black-footed ferret): 132011663
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Entry
132011663 CDS
T09425
Symbol
PLCD1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1
KO
K05857
phosphatidylinositol phospholipase C, delta [EC:
3.1.4.11
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp00562
Inositol phosphate metabolism
mnp01100
Metabolic pathways
mnp04020
Calcium signaling pathway
mnp04070
Phosphatidylinositol signaling system
mnp04919
Thyroid hormone signaling pathway
mnp04933
AGE-RAGE signaling pathway in diabetic complications
Module
mnp_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
132011663 (PLCD1)
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
132011663 (PLCD1)
04070 Phosphatidylinositol signaling system
132011663 (PLCD1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
132011663 (PLCD1)
09160 Human Diseases
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
132011663 (PLCD1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mnp04131
]
132011663 (PLCD1)
Enzymes [BR:
mnp01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
132011663 (PLCD1)
Membrane trafficking [BR:
mnp04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
132011663 (PLCD1)
Endocytosis
Macropinocytosis
Phospholipase C
132011663 (PLCD1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
EF-hand_like
EF-hand_10
C2
PH_12
PH
EF-hand_7
EF-hand_6
EF-hand_15
EF-hand_1
WHD_MCM8
EF-hand_5
TEP1_N
SPARC_Ca_bdg
Motif
Other DBs
NCBI-GeneID:
132011663
NCBI-ProteinID:
XP_059246539
LinkDB
All DBs
Position
2:62410683..62434150
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AA seq
777 aa
AA seq
DB search
MQCLGFPSRSRSRELYLQEQSLKVAALNGQRLGLQDDEDLQALLKGSQLLKVKSNSWRRE
RFYKLQEDCKTIWQESRKVMRTPESQLFSIEDIQEVRKGHRTEGMEKFARDVPEDRCFSV
VFKDQRNTLDLIAPSPAEAQHWVQGLRKIIHHSGSMDQRQKLQHWIHSCLRKADKNKDNK
MSFKELQNFLKELNIQVDDSYARKIFRECDHSQTDSLEDDEIEAFYKMLTQREEIDRTFA
EAAGSRETLSVDQLVTFLQHQQREEAAGPALALSLIERYEPSETAKAQRQMTKDGFLMYL
LSADGSAFSLAHRRVYQDMGQPLSHYLMSSSHNTYLLEDQLTGPSSTEAYIRALCKGCRC
LELDCWDGPNQEPVIYHGYTFTSKILLCDVLRAIRDYAFKASPYPVILSLENHCSLEQQR
VMARHLRTILGPMLLDRPLDGVTTSLPSPEQLKGKILLKGKKLGGLLPPGGEGGPEATVV
SDEDEAAEMEDEAVRSRVQRKPREDKLRLVKELSDMVIYCKSVHFGGFSSPGTPGQAFYE
MVSFSENRALRLLQESGNSLVRHNVNHLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNF
QTPGPEMDVYQGRFQDNGACGYVLKPAFLRDPNSTFNSRALTQGPWWTRKRLTVRVISGQ
QLPKVNKNKNSIVDPKVTVEIHGVGRDMASRQTAVVTNNGFNPWWDTEFEFEVVVPELAL
VRFVVEDYDASSKNDFIGQSTIPLGSLKQGYRHVHLLSKNGDQHPSATLFVKVSLQD
NT seq
2334 nt
NT seq
+upstream
nt +downstream
nt
atgcaatgcctaggattcccgagcaggagccgctccagagagctctacttgcaggagcag
agcctcaaggtggcagcgctcaatgggcagaggctgggcctacaggatgatgaggaccta
caggcactgctaaagggcagccagctcctgaaggtgaagtccaactcatggcggcgagaa
cgtttctacaagttgcaggaagactgcaagaccatctggcaggagtcgcgcaaggtcatg
cggaccccagagtcccagctgttctccattgaggacattcaggaggtgcggaaggggcac
cgcacagagggcatggagaagttcgcccgggatgtgcccgaggaccgttgcttctccgtg
gtcttcaaggaccagcgcaacacactagacctcattgcaccatcgccagcggaggcccag
cactgggtacagggtctgcgcaagatcatccatcactcgggctccatggaccagaggcag
aagctgcagcactggattcactcctgcttgcgaaaagctgacaaaaacaaggacaacaag
atgagcttcaaggagctgcagaacttcctgaaggagctcaacatccaggtggatgacagc
tatgcccggaagatcttcagggaatgtgaccactcccagacggactccctggaggatgat
gagattgaggctttctacaagatgctgacccagcgggaggagattgaccgcaccttcgcg
gaggcggcaggctccagggaaacgctgtcggtggatcagctggtgacgttcctgcagcac
cagcagcgggaggaggcggcagggcctgcactggccctctccctcattgagcgctatgag
cccagtgagactgccaaggcgcagcggcagatgaccaaggatggcttcctcatgtacctg
ctgtctgccgacggcagcgccttcagcctggcacaccggcgggtctaccaggacatgggc
cagccgctcagccactacctgatgtcctcctcgcacaacacctacttgctggaagaccag
ctcacagggcccagcagcactgaagcctacatccgggcgctgtgcaaaggctgccgctgc
ctggagctcgactgctgggacggccctaaccaggagccggtcatctaccacggctacacg
ttcacctccaagatccttctctgcgacgtgctcagggccatccgggactacgccttcaag
gcgtccccctaccccgtcatcctgtccctggagaatcactgcagcctggagcagcagcgt
gtgatggcgcgacacctgcgcaccatcctgggccccatgctgttggaccggcccctggac
ggggtcaccaccagtctgccttcccctgagcaactgaaggggaagatcttgctgaagggg
aagaagcttggggggctcctgccccctggcggggagggtggccctgaagccactgtcgtg
tctgatgaggacgaggctgctgagatggaggacgaagccgtgaggagccgtgtgcagcgc
aagcccagggaggacaagctcaggctagtgaaggagctctccgatatggtcatttactgc
aagagtgtccactttgggggcttctccagccctggcacaccagggcaggctttctatgag
atggtgtccttctccgagaaccgcgccctccggctgctccaagagtcaggaaacagctta
gtgcgccacaatgtcaatcacctgagcagaatctaccctgctgggtggagaacggactcc
tccaactacagccctgtggagatgtggaacgggggctgccagatcgtggccctgaatttc
caaacacctggcccagagatggatgtataccagggccgcttccaggacaacggggcctgc
gggtatgtgctgaagcccgccttcctgcgagatccgaactctacctttaactcacgtgcc
ctgactcaggggccctggtggacccggaagcggctcactgtcagggtaatctccgggcag
cagttgccaaaagtcaacaagaataagaattcaattgtggaccccaaggtgacggtggag
atccacggtgtgggccgggacatggccagccgccagacagctgtagtcaccaataacggt
ttcaacccgtggtgggacacagagtttgagtttgaggtggtcgtgcctgagcttgccctc
gtgcgctttgtggtggaggattatgacgcatcctccaagaacgacttcattggtcagagc
accatccccttgggcagtctcaagcaaggataccgccatgtccatctcttgtctaagaat
ggagaccagcacccgtctgccaccctctttgtgaaggtgtctctccaggactag
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