Mustela nigripes (black-footed ferret): 132011747
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Entry
132011747 CDS
T09425
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
132011747 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
mnp03032
]
132011747 (TOP2B)
03036 Chromosome and associated proteins [BR:
mnp03036
]
132011747 (TOP2B)
Enzymes [BR:
mnp01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
132011747 (TOP2B)
DNA replication proteins [BR:
mnp03032
]
Eukaryotic type
DNA Topoisomerases
132011747 (TOP2B)
Chromosome and associated proteins [BR:
mnp03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
132011747 (TOP2B)
Centrosome formation proteins
Centriole proteins
132011747 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
132011747
NCBI-ProteinID:
XP_059246816
LinkDB
All DBs
Position
2:77764174..77823386
Genome browser
AA seq
1619 aa
AA seq
DB search
MAKAGGGAGAGGNGALTWVTLFDQNNASKKEESETANKNDSSKKLSVERVYQKKTQLEHI
LLRPDTYIGSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMT
CIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRN
GYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDL
SKFKMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETG
VALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKK
KNKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAAS
NCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGD
SAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYD
DAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKN
KQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGP
EDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKEL
ILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQA
LMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLSRLLFPAVDD
NLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGL
DPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPM
LNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLF
DHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKI
TIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEETQNQHDDSSSDSGTPSGPDFN
YILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQER
EDILAGMAGKAIKGKVGKPKVKKLQLEETMPSPYGRRIVPEITAMKADASKKLLKKKKGD
LDTTAVKVEFDEEFSGTPVEGTGEEALISSAPVNKGPKPKREKKEPGTRVRKTPTSSGKS
SAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADD
DDDNNDLEELKVKASPITNDGEDEFIPSDGLDKDEYTFSPGKSKATPEKSSHDKKSQDFG
NLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTTA
KPKRAPKQKKVEPINSDSDSEFGIPKKTTPLKGKGRGAKKRKASGSENEGDYNPGRKTSK
TTSKKLKKTSFDQDSDVDIFPSDFTSEPPSLPRTGRARKEVKYFAESDEEEDVDFAMFN
NT seq
4860 nt
NT seq
+upstream
nt +downstream
nt
atggccaaggcgggcggcggcgcgggagccggcggcaacggggcactgacctgggtgact
ctttttgatcagaacaatgcctcaaaaaaggaagagtcagaaaccgcaaacaaaaatgat
tcttcaaagaagttgtctgttgagagagtgtatcagaaaaagacacaacttgaacatatt
ctccttcgtcctgatacgtatattgggtcagtggaaccattgacacagctaatgtgggta
tatgatgaagatgtaggaatgaattgcagagaggttacctttgtgccaggtttatacaag
atctttgatgaaattttggtcaatgcagctgacaataaacagagggacaagaatatgact
tgtattaaagtttctattgatcctgaatcaaatattataagcatttggaataatgggaaa
ggcattccagtagtggaacacaaagtagagaaagtatatgttcctgcgttaatttttgga
cagcttttaacatccagtaactatgatgatgatgagaaaaaagtaacaggtggtcgcaat
ggttatggtgcaaaactttgtaatattttcagtacaaaatttacagtagaaactgcttgc
aaagaatacaaacacagttttaagcagacatggatgaataacatgatgaagacttctgaa
gccaaaattaaacattttgatggtgaagattacacatgcataacattccaaccagatctg
tctaaatttaagatggaaaaacttgacaaggatattgtggcccttatgaccagaagagct
tatgatttggctggttcatgcaagggtgtcaaggtcatgtttaatggaaagaaattgcct
gtaaatggatttcgcagttatgtagatctttatgtgaaagacaagttggatgaaactgga
gtggccctgaaagttattcatgaacttgcaaatgaaagatgggatgtttgtctcacactg
agtgaaaagggattccagcaaatcagctttgtaaatagtattgcaacaacaaaaggtgga
cgtcatgtggattatgtagtagatcaagttgttggtaaactgattgaagtagttaagaaa
aagaacaaagccggtgtatcagtaaaaccatttcaagtaaaaaaccatatatgggttttt
attaactgccttatcgaaaatccaacttttgattctcaaactaaggaaaacatgactctg
caacccaaaagttttgggtccaaatgccaactgtcagaaaaattttttaaagcagcttct
aactgtggcattgtagaaagtattctgaattgggtgaaatttaaggcccagactcagctg
aacaagaagtgttcatcagtaaagtatagtaaaatcaaaggtattcccaaactggatgat
gctaatgatgctggtggcaaacattccctggagtgtacactgatactaaccgagggagac
tctgccaaatcattggctgtgtctggattaggtgtgattgggcgagacagatatggagtc
tttccacttaggggaaaaattcttaacgtacgggaagcttctcataaacagatcatggaa
aatgcagaaataaacaatattatcaaaatagttggtctacagtacaagaaaagttatgat
gatgcagaatctctgaaaactttacgctatgggaagattatgattatgactgatcaggat
caagatggttctcacataaaaggtctgcttattaatttcatccatcacaattggccatca
cttttgaagcatggttttcttgaagagttcattactcctattgtaaaggctagcaaaaat
aaacaggaactttccttctatagtattcctgaatttgatgagtggaaaaaacatatagaa
aaccagaaagcctggaaaataaaatactacaaagggttgggtaccagtacagctaaagaa
gcaaaggaatattttgctgatatggaaaggcaccgcatcttatttagatatgctggtcct
gaagatgatgctgccattaccttggcattcagtaaaaagaagattgatgatagaaaagaa
tggttaacaaattttatggaagaccggagacagcgtaggttacatggcttaccagagcaa
tttttgtatggtacagcaacaaagcatttgacttacaatgatttcatcaacaaggaattg
attctcttctcaaattcagacaatgaaagatctataccatctcttgttgatggatttaaa
ccaggacaacgaaaagttttatttacttgtttcaagaggaatgataaacgtgaagtaaaa
gttgcccagttggctggatctgttgctgagatgtctgcttatcatcatggagagcaagca
ttgatgatgactattgtgaatttggctcagaactttgtgggaagcaacaacattaatttg
cttcagcctattggtcagtttggaactcggcttcatggtggcaaagatgctgcaagccct
cgttatattttcacaatgttaagctctttatcaagactgctttttcctgctgtggacgac
aacctgcttaaattcctttatgatgataatcaacgtgttgagcctgagtggtatattcct
ataattcccatggttttaataaatggtgctgagggcattggtactggatgggcttgtaaa
ctacccaactatgatgctagggaaattgtgaacaatgtcagacgaatgctagatggcttg
gatcctcatcctatgcttccaaactacaaaaactttaaaggaaccatccaagagcttggt
caaaaccagtatgcagtcagtggtgaaatatttgtggtggatagaaacacagtagagatt
acagagcttccagttagaacttggacacaggtatacaaagaacaggttttagaaccaatg
ctcaatggaacagataaaacaccagcattaatttctgattataaagaatatcatactgat
acaactgtgaaatttgtggtgaaaatgactgaagagaagcttgcacaagcagaagctgct
ggattgcacaaagtttttaaacttcagactactcttacttgtaattccatggtactcttt
gatcatatgggatgtctcaagaagtatgaaactgttcaagacatcttgaaagaattcttt
gatttacgattaagttactatggtttacgtaaggaatggcttgtaggaatgttgggagca
gagtccacaaagcttaacaatcaagcccgtttcattttagagaagatacaaggaaaaatt
actatagagaataggtcaaagaaagatttgattcaaatgttagtccagagaggttatgaa
tctgacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagaggaagaaaca
caaaaccagcatgatgatagttcctctgattcaggaactccttcaggccccgattttaat
tatattttaaatatgtctctgtggtctcttactaaagaaaaagttgaagaactgattaaa
cagagagatgcaaaagggcgagaggtcaatgatcttaaaagaaaatctccttcagatctt
tggaaagaagacttagcagcatttgttgaagaactggataaagtggaagcgcaagaacgg
gaggatattctggctggaatggcaggaaaagcaataaaaggtaaagttggcaaacctaag
gtgaagaaacttcaactggaagagacaatgccctcaccttatgggagaagaatagttcct
gaaattactgctatgaaggcagatgccagcaaaaagttgctgaagaagaaaaagggtgat
cttgataccacagcggtaaaagtagaatttgatgaagaatttagtggaacaccggtagag
ggtactggagaagaggcattgatctcgtcagctcctgtaaataaaggtcccaaacccaaa
agggaaaaaaaggaacctggtaccagggtgagaaaaacacctacatcctctggtaaatcc
agtgcaaagaaagtgaagaaacggaatccttggtcagatgatgaatccaagtcagaaagt
gacctggaagaaacagaacctgtggttattccaagagattctttacttaggagagcagct
gcggaaaggcctaagtacacatttgatttctcagaggaagaggatgatgatgctgatgat
gatgatgataataatgatttagaggagttgaaagttaaagcatctcctataacaaatgat
ggggaagatgaatttattccttcagatggcctagataaagatgaatatacattttcacca
ggcaaatcaaaagctactccagaaaaatcttcacatgacaaaaaaagtcaagattttggg
aatctcttctcatttccttcgtactctcagaagtcagaagatgattcagctaaatttgac
agtaatgaagaagattctgcctctgtattttcaccatcatttggtctgaaacaaacagat
aaggttccaagtaaaactgtagctgctaaaaagggcaaaccatcttcagatacaactgct
aagcccaagagagcccctaaacagaaaaaagtagagcctatcaactctgattcagattca
gaatttggcattccaaagaagactacacccctaaaaggtaaaggccgaggggcaaagaaa
aggaaagcatctggctctgaaaatgaaggtgattataaccctggcaggaaaacatccaaa
acaacaagcaagaaactgaagaaaacatcttttgatcaggattcagatgtggacatcttc
ccatcagacttcacttctgaaccaccttctctgccacggaccggtagggctaggaaagaa
gtaaaatattttgcagagtctgatgaagaagaagatgttgattttgcaatgtttaattaa
DBGET
integrated database retrieval system
