Mustela nigripes (black-footed ferret): 132011867
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Entry
132011867 CDS
T09425
Symbol
MYLK
Name
(RefSeq) myosin light chain kinase, smooth muscle isoform X1
KO
K00907
myosin-light-chain kinase [EC:
2.7.11.18
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp04020
Calcium signaling pathway
mnp04022
cGMP-PKG signaling pathway
mnp04270
Vascular smooth muscle contraction
mnp04371
Apelin signaling pathway
mnp04510
Focal adhesion
mnp04517
IgSF CAM signaling
mnp04611
Platelet activation
mnp04810
Regulation of actin cytoskeleton
mnp04921
Oxytocin signaling pathway
mnp04971
Gastric acid secretion
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
132011867 (MYLK)
04020 Calcium signaling pathway
132011867 (MYLK)
04022 cGMP-PKG signaling pathway
132011867 (MYLK)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
132011867 (MYLK)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
132011867 (MYLK)
09142 Cell motility
04810 Regulation of actin cytoskeleton
132011867 (MYLK)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
132011867 (MYLK)
09152 Endocrine system
04921 Oxytocin signaling pathway
132011867 (MYLK)
09153 Circulatory system
04270 Vascular smooth muscle contraction
132011867 (MYLK)
09154 Digestive system
04971 Gastric acid secretion
132011867 (MYLK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mnp01001
]
132011867 (MYLK)
Enzymes [BR:
mnp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.18 myosin-light-chain kinase
132011867 (MYLK)
Protein kinases [BR:
mnp01001
]
Serine/threonine kinases: CAMK group
MLCK family
132011867 (MYLK)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
I-set
Ig_3
ig
Ig_2
Pkinase
23ISL
V-set
PK_Tyr_Ser-Thr
Ig_VEGFR-1-like_5th
C2-set_2
VEGFR1-3_N_Ig-like
Ig_MYOM1
fn3
Ig_4
V-set_CD47
Receptor_2B4
FN3_DSCAM-DSCAML_C
Fn3_PBP1
Ig_SEMA-3_4_7A
Kinase-like
Kdo
DUF5898
AvrM_N
Ig_J_second
Motif
Other DBs
NCBI-GeneID:
132011867
NCBI-ProteinID:
XP_059247066
LinkDB
All DBs
Position
2:complement(99045722..99311077)
Genome browser
AA seq
1974 aa
AA seq
DB search
MGDVKLAASTQVSKASISVDHSRAGSVPLTDAPAFIVPPRNLCIREGATAKFEGRVRGYP
EPHVTWHRNGQPITSGGRFLLDCSIRGAFSLVIRAVREEDKGKYTCEATNDSGARQVTVE
LTVEGGFIKKHGQPAVSKTLGDRFAAPAVETRPSIWGECPPKFATKLGRAIVREGQMGRF
SCKITGRPQPQVTWLKGEVPLQPSARVSMSEKNGVQVLEIHEVSRDDVGVYTCLVVNGSG
KASMSAELSIQGLDNANRSLVRGTKAPSSDIRKEVTNGTTQGTKVDSLESAAERRNCSSA
QRGSSLTWAPSSQPQPLQESQPELSEDSSRKALRSPILQKTSSTITLQAAKVQPEPRALI
SSTLSSSGEEREWPAAPHQATHPTRQTGLGSQEVVSKVATRKIPVESQRDSTFPKFESKP
QSQEISEDQTVKFRCEVSGTPKPEVTWFLEGAPVRRREGMVEMYEEGGCHYLCLLRARPR
DSGSYSCTASNVRGQVSCGWNLLVKRLAALEVAPSFSRVLKDCTVVEGQDFVLQCSVQGT
PVPQITWLLNEQPIQYAHSSCEAGVAELHIQDALPEDDGIYTCLAKNTVGQVSCSARVTV
HERKSDRKSGSLLPAAPSKPVAPVFLQGLSDLKVMDGSHVTMTVQVSGNPPPEVIWLHDG
NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSVGEVHTQAVLMVQEPQDGTQ
PWFISRPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALSKDTGHFEVLQNEGVFTLV
LKNVQPWHAGQYEILLKNRVGECSCQVSLMLQSNPTRAPLRGREPASCEGLCSQGAGADG
GGRDCYGTLRPGWPARGQGWPEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL
LGKKVSTKTVSEEDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK
GTPKTPVPEKAPLPKPATPDFRSVLGSKKKLPAENGSNNAEALNAKAAESPKAVSNAQPL
GSLKPLGNAKPAETLKPVGNAKPAEPTKPVGNAKPAETPKPIGNAKPAETPKPMGNAKPA
ETPKPMGNAKPAETPKPIGNAKPAETPKPMGNAKPAETPKPAGKEELKKEVKNDVNCRRG
QAGATDNENRSENQGTAPTFKEKLQDVRVTEGEKLLLQCQVSSDPPATITWTLNGKTLKT
TKFIILSQEGSLCSVSIEKALPEDRGLYKCIAKNGAGQAECSCQVTVDDAPTKENVKAPE
MKARRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK
VAGTQPITCTWMKFRKQIQESEHIKVENSENGSRLTIVAARQEHCGCYTLLVENKLGSRQ
AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSVEIWDSVDKTWKE
LATCRSTSFNVQDLLPDREYKFRVRAINVYGTSEPSQESELTAVGEKPEEPKDEVEASDD
DEKEPEIDYRNVTVNTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTGKIWAGKFFKAYSA
KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER
ECIQYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARKLENAGSLKV
LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF
DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM
ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV
AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD
EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
NT seq
5925 nt
NT seq
+upstream
nt +downstream
nt
atgggggatgtgaagctggctgcctcaacacaggtttctaaagcttccatcagtgtggat
cactcgagagccggttccgtgcccctgaccgacgcccctgctttcattgtgccccctcgg
aacctctgcatcagagaaggagccaccgccaagttcgaagggagggtccggggttaccca
gagccccacgtgacgtggcaccgaaatgggcaaccaatcaccagtgggggccgcttcctg
ctggactgcagtatccggggagctttcagccttgtgattcgtgctgtccgggaggaggac
aaaggaaagtatacctgtgaagccaccaatgatagtggtgcccgccaagtgactgtggag
ttgacggtggaagggggctttattaagaagcatggtcagcctgctgtttctaaaaccttg
ggggacagattcgctgcccctgccgtggagactcgtcctagcatctggggagagtgccca
ccaaagtttgctaccaagttgggccgagccatagtccgagaaggacagatgggacggttt
tcgtgcaagatcactggccggccccaaccacaggtcacctggctcaagggagaggttccc
ctgcagccaagtgcccgtgtgtctatgtctgagaagaatggggtacaagttctggaaatc
cacgaggtcagccgcgatgatgtgggcgtgtacacatgcctggtggtgaatgggtcaggg
aaggcctccatgtcggccgaactttctatccaaggtttggacaatgccaataggtcactg
gtgagaggaacaaaggcacccagttcagatatcaggaaggaagtgaccaatggaaccaca
caggggacgaaagtggacagcctggagtctgccgccgaaagaaggaactgctccagcgcc
cagagggggagctccctgacctgggccccaagtagccagcctcagcccctgcaggagtcc
cagccagagctgtccgaggactcatccaggaaggccctgaggagccccatcttacagaag
acttctagtaccatcaccctgcaggctgcaaaagtccagccggaacccagagcactgatc
tcgagcaccctctcgtcttctggagaagagagggagtggccagctgcaccccaccaagcc
actcaccctaccaggcagactggtctgggaagccaggaggtggtgagcaaggttgctacc
aggaaaatccccgtagagagccagagggactccaccttccccaaatttgagagcaagccc
caaagccaggaaatcagtgaagatcagacagtcaagttcagatgtgaggtttcagggacc
ccaaaacctgaagtgacctggttcttggaaggtgcccccgtgaggagacgagaaggcatg
gttgagatgtatgaagaaggtggatgccattacctctgcctgctgagagcacggcccagg
gacagtgggagctatagctgcacggcctccaatgtccggggccaggtgtcctgtggttgg
aacctcctggtgaaacgtctggctgcactggaggtagcaccctcgttctccagggtcctg
aaggactgcactgtcgtcgagggccaggactttgtgctgcagtgctcagtgcaggggacc
ccggtcccccaaattacttggctgctcaatgagcagcccatccagtatgctcactcctcc
tgtgaggctggcgtggccgagctccacatccaggacgccctgccggaagatgacggcatc
tacacctgtctggccaagaacaccgtggggcaggtgtcctgcagcgcccgggtcactgtc
catgaaaggaagagtgacaggaagagcgggtccctcctgcccgcagctcccagcaagcct
gtcgcaccggtattcctgcagggcctctccgacctcaaagtcatggatggaagccacgtc
accatgacagtccaggtgtcagggaacccaccccctgaggtcatctggcttcacgatggg
aatgagatccaggagtcagaagacttccactttgagcagagaggcactcagcacagcctc
tgtatccaggaagtgttcccagaggacacaggcacatatacctgtgaagcctggaacagt
gtcggagaggtccacacccaggcggtgctcatggtgcaagagcctcaggatggtacccag
ccctggttcatcagcaggcctcgctcagtgacagcctccctgggccagagtgtcctcatc
tcctgtgccatcgctggggaccccttccctactgtgcactggctgcgagacggcaaagcc
ctctccaaagacactggccacttcgaggtgctacagaatgagggcgtgttcacactggtt
ctaaagaatgtgcaaccttggcatgccggccaatatgaaatcctgctcaagaaccgggtt
ggcgaatgcagttgccaggtgtcactgatgttacagagcaaccccaccagagcccccctg
cgggggagggagcctgccagctgtgagggcctctgcagccagggagccggtgctgatggt
ggtggccgtgactgctatgggaccctgaggcccggctggcctgcgagagggcagggttgg
ccggaggaggaagacggcgaggacgttcggggggtgctaaagaggcgcgtggagactcgg
cagcacacggaggaggccatccgccagcaggaggtggaacagctggacttccgtgacctc
ctggggaagaaggtgagtaccaagaccgtgtcagaagaagacctcaaggagatcccagct
gagcagatggatttccgcgccaacctgcagcggcaggtgaagccgaagacggtgtcagag
gaagagagaaaggtgcacagccctcagcaggtcgacttccgctcggtcctagccaaaaag
gggactcctaagaccccggtgcctgagaaggcgccgcttcccaaacctgccaccccagat
ttccgctcggtgttaggcagcaagaagaaattaccagcagagaacggtagcaacaacgct
gaggccttgaatgccaaggcagcagaaagtcccaaggctgtgagcaatgcccagccttta
gggtccctgaaacccttgggcaatgccaagcctgctgaaaccctaaaacctgtgggcaat
gccaaacctgccgagcccacgaaacccgtgggcaatgccaagcctgctgagaccccaaaa
cccataggcaacgccaagcctgctgagaccccaaaacccatgggcaacgccaagcctgct
gagactccaaaacccatgggcaacgccaagcctgctgagaccccgaaacccataggcaat
gccaagcctgctgagaccccaaaacccatgggcaatgccaagcctgctgagaccccaaaa
ccagctgggaaggaagaactcaagaaggaggttaagaatgatgtgaactgtaggaggggg
caagcaggagccacagataatgaaaacaggtcagagaaccaagggacagccccaaccttc
aaggagaagctacaagatgtccgtgtgacagaaggcgagaagctgctactccagtgtcag
gtgtcctctgaccccccagccaccatcacctggacactgaatggaaagacactcaagacc
accaagttcatcatcctctcccaagaaggctcactgtgctctgtctccatcgagaaggca
ctgcccgaggacagaggtttatacaagtgcatagccaagaatggcgccggccaggctgag
tgctcctgccaagtcaccgtggacgatgctcccaccaaagagaatgtcaaggccccggag
atgaaagcccggaggcccaagagctctcttccccctgtgctaggaacagagagtgatgca
actgtgaaaaagaaacctgcccccaagacgcctccgaaggcagccatgccccctcagatc
atccagtttcccgaggaccagaaggtgcgcgcaggagagtctgtggagctgtttgggaaa
gtggcaggcacccagcccatcacctgtacttggatgaagttccgaaagcagatccaggag
agcgagcacatcaaggtggagaacagcgagaatggcagcaggctcaccatcgtggccgca
cgccaggaacactgcggctgctacactctgctggtggagaacaagctgggcagcaggcag
gcccaggtcaacctcactgtcgtggacaagccagaccccccagctggcacgccttgcgcc
tctgacatccggagctcctcgttgaccctgtcctggtatggctcttcatacgacgggggc
agtgccgtgcagtcctacagcgtcgagatctgggactccgtggacaaaacgtggaaggag
ctagccacatgccgcagcacctcttttaacgtccaggacctcctgcctgaccgagagtat
aaattccgtgtgcgtgccatcaatgtgtatggaaccagtgagccgagccaggagtctgaa
ctcacagcagtgggagagaaaccagaggagccaaaggacgaagtggaggcctcagatgat
gatgagaaggaacctgagatcgactaccggaacgtgactgtcaacactgaacaaaaagtg
tctgacttctatgacatcgaagagagactaggctctgggaaatttggacaggtctttcga
cttgtagagaagaaaactggaaaaatctgggcagggaaattcttcaaggcatattctgca
aaagagaaagagaatatccggcaggagatcagcatcatgaactgcctccaccaccccaag
ctggtccagtgtgtggacgctttcgaagaaaaagccaacatcgtcatggtcctggagatc
gtgtcggggggtgagctgttcgagcgcatcatcgacgaggacttcgagctgacggagcgg
gagtgcattcagtacatgaggcagatatcagaaggggtggaatacatccacaagcagggc
atcgtccacctggacctcaagcccgagaacatcatgtgtgtcaataaaaccggcaccaga
atcaagctcattgacttcggtctggccagaaagctggagaatgcggggtctctgaaggtc
ctctttggcaccccggagtttgtggctcctgaagtcatcaactacgagcccatcggctat
gccacagacatgtggagcatcggagtcatctgctacatcctggttagtggactttccccc
ttcatgggtgacaacgataatgaaaccctagccaacgttacctcagccacctgggacttc
gatgatgaagcgttcgatgagatctctgatgatgccaaggattttatcagcaatttactg
aagaaagatatgaaaaaccgcctagactgcacccagtgccttcagcatccatggctaatg
aaagacaccaagaacatggaggccaagaaactctccaaggaccggatgaagaagtacatg
gcaagaaggaaatggcagaaaacgggcaatgctgtgagagccattggaagactgtcctct
atggcaatgatctcaggactcagtggcaggaaatcctcaacagggtcaccaaccagccca
ctcaatgcagaaaaattagaatctgaagaagatgtgtctcaagctttccttgaggctgtt
gctgaggaaaagccccatgtaaaaccctatttctctaagaccatccgtgatttagaagtt
gtggagggaagcgctgctagatttgactgcaagattgaaggatacccagaccctgaagtt
gtctggttcaaagatgaccagtcaatccgggagtctcgccacttccagatagactacgat
gaggatgggaactgctctttaatcattagcgatgtttgcggggacgatgatgccaagtac
acctgcaaggccgtcaacagtctgggagaagccacctgcacagcggagctcattgtggag
accatggaggaaggagaaggggaaggggaagaagaggaagagtga
DBGET
integrated database retrieval system
