Mustela nigripes (black-footed ferret): 132015570
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Entry
132015570 CDS
T09425
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase 3 isoform X1
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp00220
Arginine biosynthesis
mnp00330
Arginine and proline metabolism
mnp01100
Metabolic pathways
mnp04020
Calcium signaling pathway
mnp04022
cGMP-PKG signaling pathway
mnp04066
HIF-1 signaling pathway
mnp04071
Sphingolipid signaling pathway
mnp04151
PI3K-Akt signaling pathway
mnp04370
VEGF signaling pathway
mnp04371
Apelin signaling pathway
mnp04611
Platelet activation
mnp04915
Estrogen signaling pathway
mnp04921
Oxytocin signaling pathway
mnp04926
Relaxin signaling pathway
mnp04931
Insulin resistance
mnp04933
AGE-RAGE signaling pathway in diabetic complications
mnp05415
Diabetic cardiomyopathy
mnp05417
Lipid and atherosclerosis
mnp05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
132015570 (NOS3)
00330 Arginine and proline metabolism
132015570 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
132015570 (NOS3)
04371 Apelin signaling pathway
132015570 (NOS3)
04066 HIF-1 signaling pathway
132015570 (NOS3)
04020 Calcium signaling pathway
132015570 (NOS3)
04071 Sphingolipid signaling pathway
132015570 (NOS3)
04022 cGMP-PKG signaling pathway
132015570 (NOS3)
04151 PI3K-Akt signaling pathway
132015570 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
132015570 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
132015570 (NOS3)
04921 Oxytocin signaling pathway
132015570 (NOS3)
04926 Relaxin signaling pathway
132015570 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
132015570 (NOS3)
05418 Fluid shear stress and atherosclerosis
132015570 (NOS3)
05415 Diabetic cardiomyopathy
132015570 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
132015570 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
132015570 (NOS3)
Enzymes [BR:
mnp01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
132015570 (NOS3)
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Gene cluster
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
132015570
NCBI-ProteinID:
XP_059252099
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All DBs
Position
4:complement(5742700..5760641)
Genome browser
AA seq
1204 aa
AA seq
DB search
MGNLKSVGQEPGPPCGLGLGLGLGLCGKQGPASPTSSEPSRAPAPTPAPPPAPDRSSPPL
TRPPDGPKFPRVKNWEVGSITYDTLSAQSQQDGPCTPRRCLGSLVFPRKLQSRPSQDPQP
TEQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWR
NAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRG
DFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEP
PELFALPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMS
TEIGARNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVTIVD
HHAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYVLSPAFRYQPDP
WKGSGSKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLG
RLFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNS
SPRPEQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPH
FCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQASCETFCVGEDAKAA
ARDIFSPKRSWKRQRYRLSTQAEGLQLLPGLIHVHRRKMFQATVLSVENLQSSKSTRATI
LVRLDTGGQEALQYQPGDHIGICPPNRPGLVEALLSRVEDPPPPGEPVAVEQLEKGSPGG
PPPGWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEESSEQQELESLSQDPRR
YEEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSAHPGEIHLTVAV
LAYRTQDGLGPLHYGVCSTWLSQLKAGDPVPCFIRGAPSFRLPPDPTLPCILVGPGTGIA
PFRGFWQERLHDIDSKGLQPAPMTLVFGCRCSQLDHLYRDEVQDAQQRGVFGRVLTAFSR
EPDSPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATSVLQTVQRILATEGDMEL
DEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERHLRGAVPWAFDPPGPD
TPSP
NT seq
3615 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagtgtgggccaggagcccgggcccccctgtggcctggggctgggc
ctgggcctggggctgtgcggcaagcagggtccggcctcccccacctcctctgagcccagc
agggcacccgcgcccacgcccgcgcccccacccgcaccagaccgcagcagccccccactc
acccggcccccggacgggcccaagttccctcgagtgaagaactgggaggtggggagcatc
acctacgataccctgagtgcccagtcacagcaggatgggccctgcaccccccgacgctgc
ctgggctcgctggtgttcccgcggaaactgcagagtcggccatctcaggacccccaaccc
acggagcagctgctgagtcaggccagggactttatcaaccagtactacagctccatcaag
aggagcggctcccaggcccatgagcagaggcttcaggaggtggaagccgaggtggcagcc
acgggcacctaccagctccgggagagtgagctggtgttcggggccaagcaggcctggcgc
aacgcaccccgctgcgtgggccggatccagtgggggaagctgcaggtgtttgatgcccgg
gactgcagctcagcccaggagatgttcacctacatctgcaaccacatcaagtatgccacc
aaccggggcaacctccgctcagccatcacagtgttcccccagcgcgccccaggccgggga
gacttccgaatctggaacagccagctggtacgctatgcgggctacaggcagcaggatggc
tcagtgcggggggacccagccaacgtggagatcaccgagctctgcatccagcatggctgg
accccaggaaacggccgctttgacgtgctgccactcctgctccaggccccggatgagccc
ccagagctctttgctctgccccccgagctggtcctcgaggtgcccctggagcaccccacg
ctggagtggtttgcagccctgggcctgcgctggtacgccctcccggcggtgagtaacatg
ctgctggagatcgggggcctggagttccccgcggcccctttcagcggctggtacatgagc
acggagatcggcgcgcggaacctgtgtgaccctcaccgatataacatcctggaggatgtg
gcagtctgcatggacttggacaccaggacaacctcatccctgtggaaagacaaggcagca
gtggaaatcaatttggccgtgctgcacagttaccagctggccaaagtgaccattgtggac
caccacgctgccaccgcctccttcatgaagcacctggagaacgagcagaaggctaggggg
ggctgccctgccgattgggcctggatcgtgccccccatctctggcagcctcacccctgtc
ttccatcaggagatggtcaactacgtcctgtcccctgccttccgctatcagccagaccca
tggaaggggagtggatccaagggtaccggcatcaccaggaagaagacctttaaggaagtg
gccaatgcagtgaagatctcagcctcactcatgggcactgtgatggcaaagcgagtgaag
gcgaccatcctgtatggctccgagaccggccgggcccagagctacgcacagcagctgggg
agactcttccggaaggctttcgacccccgggtcttgtgcatggatgagtatgatgtggtg
tcccttgagcatgagacgctggtgttggtggtgaccagtacgtttgggaatggtgacccc
ccagagaatggagagagttttgcggcggccctgatggagatgtcgggcccctacaacagc
tcccctcggccagaacagcacaagagttacaaaatccgcttcaacagcgtctcctgctca
gacccgctggtgtcctcttggaggcggaagagaaaggagtccagtaacacagacagcgca
ggggccctggggaccctcaggttctgtgtgttcgggctgggctcccgggcatacccccac
ttctgcgcctttgctcgtgcggtggacacacggctggaagagctgggcggggagcggcta
ctgcagctgggccagggagatgagctgtgcggccaggaggaggccttccgtggctgggcc
caggctgccttccaggcctcctgtgagactttctgcgtgggagaggatgccaaggccgct
gcccgggacatattcagccccaaacggagctggaagcgccagcggtaccggctgagcacc
caggccgagggcctccagctgctgccaggcctgatccacgtgcacaggagaaagatgttc
caggctacggtcctctcagtggaaaacctgcaaagcagcaagtccacccgggccaccatc
ctggtgcgcctagacaccggaggccaggaggcgctacagtaccagcccggggatcacata
ggcatctgcccgcccaaccggccaggcctcgtggaggcactgctgagccgcgttgaggat
cctcctccacccggcgagcctgtggctgtggagcagctggagaagggcagccctggtggc
ccgccccctggctgggttcgggacccccggctgcccccatgcacactgcgccaggctctc
accttcttcctggacatcacttccccgcccagtcctcaactccttcgactgctcagcacc
ctggccgaagagtccagcgaacagcaggagcttgagagcctcagccaggacccgcggcgg
tacgaggagtggaagtggttccgctgccccacgctgctggaggtgctggagcagtttcca
tcggtggccctgcccgcgccgctgctcctcacccagctgcccctgctccagccccggtac
tactcagtcagctcggcgcccagcgcccacccaggagagatccacctcacagtagctgtg
ctagcatacaggacacaggacggactgggcccccttcattatggagtctgctccacgtgg
ctgagccagctgaaggccggggatcctgtaccctgcttcatcaggggggctccctccttc
cggctgccacctgaccccaccttgccctgcatcctagtgggccctggcacaggtattgcc
cccttccggggattctggcaggagcggctgcatgacattgacagcaaaggcctgcagccc
gcccccatgactttggtgttcggctgccgatgctcccagctcgaccacctttaccgcgac
gaggtgcaggatgcccagcagcgcggagtttttgggcgcgtcctcaccgccttctcccgg
gagcccgacagccctaagacctacgtgcaggacatcctgcggacggagctggctgctgag
gtgcaccgcgtgctgtgcctcgagcggggccacatgtttgtgtgcggcgacgtcaccatg
gcaaccagcgttctgcagacggtgcagcgcatcctagcgacggagggcgacatggagctg
gacgaggccggcgacgtcatcggcgtgctgcgggatcagcaacgctatcacgaggacatt
ttcgggctcacactgcgcacccaggaggtgacaagccgcatacgcacccagagcttttcc
ttgcaggagcgacatctgcggggcgcagtgccctgggcgttcgacccgcctgggccagac
acccccagcccctga
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integrated database retrieval system
