Mustela nigripes (black-footed ferret): 132016307
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Entry
132016307 CDS
T09425
Symbol
SIRT1
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1 isoform X1
KO
K11411
NAD-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp00760
Nicotinate and nicotinamide metabolism
mnp01100
Metabolic pathways
mnp04068
FoxO signaling pathway
mnp04148
Efferocytosis
mnp04152
AMPK signaling pathway
mnp04211
Longevity regulating pathway
mnp04213
Longevity regulating pathway - multiple species
mnp04218
Cellular senescence
mnp04310
Wnt signaling pathway
mnp04922
Glucagon signaling pathway
mnp04936
Alcoholic liver disease
mnp05031
Amphetamine addiction
mnp05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
132016307 (SIRT1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
132016307 (SIRT1)
04068 FoxO signaling pathway
132016307 (SIRT1)
04152 AMPK signaling pathway
132016307 (SIRT1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
132016307 (SIRT1)
09143 Cell growth and death
04218 Cellular senescence
132016307 (SIRT1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
132016307 (SIRT1)
09149 Aging
04211 Longevity regulating pathway
132016307 (SIRT1)
04213 Longevity regulating pathway - multiple species
132016307 (SIRT1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
132016307 (SIRT1)
09165 Substance dependence
05031 Amphetamine addiction
132016307 (SIRT1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
132016307 (SIRT1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mnp03036
]
132016307 (SIRT1)
03029 Mitochondrial biogenesis [BR:
mnp03029
]
132016307 (SIRT1)
Enzymes [BR:
mnp01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
132016307 (SIRT1)
Chromosome and associated proteins [BR:
mnp03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
132016307 (SIRT1)
Mitochondrial biogenesis [BR:
mnp03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
132016307 (SIRT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SIR2
DUF592
Motif
Other DBs
NCBI-GeneID:
132016307
NCBI-ProteinID:
XP_059253518
LinkDB
All DBs
Position
4:134595165..134621719
Genome browser
AA seq
747 aa
AA seq
DB search
MADEAALALQPGGSPSAVAAEREAASPPVGEPLRKRPRKDCPGLGRSPGEPGGAAPEREV
PAATGGCPAAAAALWREAAASAAAAGGEREAQAATAGEGDNGPGLQGLSREPPPADDFYD
DDDDDEGEEEEEAAAAAIGYRDDLLFDDEIITNGFHSCESDEDDRASHASSSDWTPRPRI
GPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINT
IEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAIDFPDLPDPQAMFDIEYF
RKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQC
HGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQF
HRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDC
DVIINELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELAHLSELPPTPLNISEDSSSPE
RTSPPHSSVIVKLLDQASKSNVDNPGVSESNDCMEEKSQEGQNSTKNIESVTEQVESPDV
RNVGSNTGEKNERTLVADSVRKCWPARLAKEQISKRLDGNQYLFLPPNRYIFHGAEVYSD
SEDDILSSSSCGSNSDSGTCQSPSLEEHLEDESEIEEFYNGLEDEADVNDRAGGTGFGIG
GGDQEAVSEALSMKQEATDINYPSNKS
NT seq
2244 nt
NT seq
+upstream
nt +downstream
nt
atggcggacgaggcggcgctcgcccttcagcccggcggctccccctcggcggtggcggcc
gagagggaggccgcgtcgccgcccgtcggggagccacttcgcaagagaccacggaaagac
tgtcccggcctggggcggagcccgggcgagcccggtggggcggcccctgaacgtgaggtg
ccggcggcgaccgggggctgccccgcggcggcggcggctctgtggcgggaggcggcggcg
tcggcggcggcggcgggcggggagcgggaggcccaggcggcgacggccggagaaggagac
aatgggccgggcctacagggcctatcccgggagccgccgccggccgacgacttctacgac
gacgacgacgacgacgagggcgaagaggaggaagaggcggcggcggcagcgattgggtac
cgagatgaccttctttttgatgatgaaataatcaccaatggttttcattcctgtgaaagt
gatgaggatgatagagcctcacatgcaagctctagtgactggactccaaggccacggata
ggtccatatactttcgttcagcaacatctcatgattggcacagatcctcgtacaattctt
aaagatttgctaccagaaacaattcctccacctgaattggatgatatgacactgtggcag
attgttattaatatcctttcagaaccaccaaaaagaaaaaaaagaaaagatattaataca
attgaagatgctgtgaaattactgcaagaatgcaaaaaaataatagttctgacaggagct
ggggtttctgtttcttgtggaatacctgacttcaggtcaagagatggtatttatgctcgc
cttgcaatagacttcccagaccttccagatcctcaagcaatgtttgatattgaatatttc
agaaaagatccaagaccattcttcaagtttgcaaaggaaatatatcctggacagttccaa
ccatctctctgtcacaaattcatagccttgtcagataaagaaggaaaactacttcggaac
tatactcagaacatagatacactggaacaggttgcgggaatccagaggataattcagtgt
catggatcctttgcaacagcatcttgtctgatttgtaaatacaaagtagactgtgaagct
gtacgaggagatatttttaatcaggtggttcctcgttgtcctagatgcccagcagatgag
ccacttgctatcatgaaaccagagattgtcttttttggtgaaaatttaccagagcagttt
catagagccatgaagtacgacaaagatgaagttgatctcctcattgttattgggtcttcc
ctgaaagtaagaccagtagcactaattccaagttccataccccatgaagtgcctcagata
ttaataaatagagaacctttgcctcatctgcattttgatgtagagcttcttggagactgt
gatgtcataataaatgaattatgtcataggttaggtggtgaatatgccaaactttgctgc
aaccctgtaaagctttcagaaattactgaaaaacctccacgaacacagaaagaattggct
catttgtcagagttgccacccacacctcttaatatttcagaagactcaagttcaccagaa
agaacttcaccaccacattcttcagtgattgttaaacttttagaccaagcatctaagagt
aatgttgataatcctggtgtgtccgagtcaaatgattgtatggaagaaaaatcacaggaa
ggacagaattctactaagaacattgaaagcgttactgaacaggtggaaagtccagatgtg
aggaatgttggctctaatactggggagaaaaatgaaagaactttagttgctgactcggtg
aggaagtgctggccagctagacttgcaaaggagcagattagcaaacggcttgatggtaac
caatatctgttcttaccaccaaaccgttatatttttcatggcgctgaggtatattcagac
tctgaagatgacatcttatcctctagttcttgtggcagtaacagtgatagtggaacatgc
cagagtccaagtttagaagaacacttggaggatgaaagtgagattgaagaattttacaat
ggtttggaagatgaagctgatgttaatgacagagctggaggaactggatttggaattggt
ggcggtgatcaagaggcagtcagtgaagctctatccatgaaacaggaagcaacagacatt
aactatccatcaaacaaatcataa
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