Mustela nigripes (black-footed ferret): 132016358
Help
Entry
132016358 CDS
T09425
Symbol
GCK
Name
(RefSeq) hexokinase-4
KO
K12407
glucokinase [EC:
2.7.1.2
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp00010
Glycolysis / Gluconeogenesis
mnp00052
Galactose metabolism
mnp00500
Starch and sucrose metabolism
mnp00520
Amino sugar and nucleotide sugar metabolism
mnp00524
Neomycin, kanamycin and gentamicin biosynthesis
mnp01100
Metabolic pathways
mnp01200
Carbon metabolism
mnp01250
Biosynthesis of nucleotide sugars
mnp04910
Insulin signaling pathway
mnp04911
Insulin secretion
mnp04917
Prolactin signaling pathway
mnp04922
Glucagon signaling pathway
mnp04930
Type II diabetes mellitus
mnp04950
Maturity onset diabetes of the young
mnp05230
Central carbon metabolism in cancer
Module
mnp_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
mnp_M00549
UDP-Glc biosynthesis, Glc => UDP-Glc
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
132016358 (GCK)
00052 Galactose metabolism
132016358 (GCK)
00500 Starch and sucrose metabolism
132016358 (GCK)
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
132016358 (GCK)
09110 Biosynthesis of other secondary metabolites
00524 Neomycin, kanamycin and gentamicin biosynthesis
132016358 (GCK)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
132016358 (GCK)
04910 Insulin signaling pathway
132016358 (GCK)
04922 Glucagon signaling pathway
132016358 (GCK)
04917 Prolactin signaling pathway
132016358 (GCK)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
132016358 (GCK)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
132016358 (GCK)
04950 Maturity onset diabetes of the young
132016358 (GCK)
Enzymes [BR:
mnp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.2 glucokinase
132016358 (GCK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Hexokinase_2
Hexokinase_1
Motif
Other DBs
NCBI-GeneID:
132016358
NCBI-ProteinID:
XP_059253576
LinkDB
All DBs
Position
4:complement(92786911..92806923)
Genome browser
AA seq
544 aa
AA seq
DB search
MGFTAFCSHRLHAGKNPSAIMEAFLSCCPSWPILSPFLQREDGTEPPVYCKRWTYEHTRS
QANPGMNPSHVTHSSNNNPKLPEKQEIQISKKEKAEQILADFQLQEADLKKVMRRMQTEM
ARGLRLQTHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGAEGQWSV
TTKHQMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDK
GILLNWTKGFKASGAEGNNIVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRRCE
VGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRVVDENS
LNPGQQLYEKLIGGKYMGELVRLVLLKLVDENLLFRGEASEQLRTRGAFETRFVSQVESD
SGDRKQIYNILSTLGLRPSATDCDIVRRACESVSTRAAHMCAAGLAGVINRMRESRSEDV
MRITVGVDGSVYKLHPSFKERFHASVRRLTPFCEITFIESEEGSGRGAALISAVACKKAC
MLGQ
NT seq
1635 nt
NT seq
+upstream
nt +downstream
nt
atggggttcacagccttttgctcccaccgcctacatgctggcaagaacccctcagccatc
atggaggccttcctaagctgctgccccagctggcccatcctgtccccattcctccagagg
gaggacggcacagagccccccgtctattgcaaaagatggacctacgagcacacccgaagt
caggccaacccgggaatgaaccccagccacgtcacgcacagctccaacaacaaccctaag
ctcccagaaaaacaggaaatacagataagcaaaaaggaaaaggccgagcagatcctggca
gacttccagctgcaggaggcggacctgaagaaggtgatgcggcggatgcagacggagatg
gcgcggggcctgcggctgcagacccacgaggaggccagtgtgaagatgctgcccacctat
gtgcgctccaccccggagggctcagaagtcggggacttcctctccctggacctgggcggc
accaacttcagggtgatgctggtgaaggtgggggagggcgcggaggggcaatggagcgtg
acgaccaagcaccagatgtactccatccccgaggacgctatgaccggcaccgcggagatg
ctgttcgactacatctccgagtgcatctccgacttcctggacaagcatcagatgaagcac
aagaaactgcccttgggcttcacattctccttccccgtgaggcatgaagacatcgacaag
ggcatcctcctcaattggaccaagggcttcaaggcctctggagcagaagggaacaacatc
gtggggctcctccgtgacgccatcaaacggagaggggacttcgaaatggacgtggtagcg
atggtcaacgatacagtggccaccatgatctcctgctactacgaagaccgccggtgtgag
gtcggcatgattgtgggcacaggctgtaacgcctgctacatggaggagatgcagaatgtg
gagctcgtggaaggggacgagggccgcatgtgcgtcaacactgagtggggcgccttcggg
gactctggggagctggacgagttcctgctggagtacgaccgtgtggtggacgagaactcc
ctgaaccccggccagcagctgtacgagaagctcattggcggcaagtacatgggcgagctg
gtgcggctcgtgctgctcaaactcgtggacgaaaacctgcttttccgcggggaggcctcg
gaacagctgcgcacgcgcggcgccttcgagacacgcttcgtgtcgcaggtggagagtgac
tctggcgaccgcaagcagatctacaacatcctgagcacgctggggctgcggccctcggcc
accgactgcgacatcgtgcgccgcgcctgcgagagcgtgtccacgcgcgccgcgcacatg
tgcgctgcggggctggcgggtgtcatcaaccgcatgcgcgagagccgcagcgaggacgtg
atgcgcatcaccgtgggcgtggacggctcggtgtacaagctgcaccccagcttcaaggag
aggttccatgccagcgtacgcaggctgacgcccttctgcgagatcaccttcatcgagtcg
gaggagggcagcggtcggggcgcggcgctgatctccgccgtggcctgcaaaaaggcctgc
atgctgggccagtga
DBGET
integrated database retrieval system