KEGG   Mustela nigripes (black-footed ferret): 132016358
Entry
132016358         CDS       T09425                                 
Symbol
GCK
Name
(RefSeq) hexokinase-4
  KO
K12407  glucokinase [EC:2.7.1.2]
Organism
mnp  Mustela nigripes (black-footed ferret)
Pathway
mnp00010  Glycolysis / Gluconeogenesis
mnp00052  Galactose metabolism
mnp00500  Starch and sucrose metabolism
mnp00520  Amino sugar and nucleotide sugar metabolism
mnp00524  Neomycin, kanamycin and gentamicin biosynthesis
mnp01100  Metabolic pathways
mnp01200  Carbon metabolism
mnp01250  Biosynthesis of nucleotide sugars
mnp04910  Insulin signaling pathway
mnp04911  Insulin secretion
mnp04917  Prolactin signaling pathway
mnp04922  Glucagon signaling pathway
mnp04930  Type II diabetes mellitus
mnp04950  Maturity onset diabetes of the young
mnp05230  Central carbon metabolism in cancer
Module
mnp_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
mnp_M00549  UDP-Glc biosynthesis, Glc => UDP-Glc
Brite
KEGG Orthology (KO) [BR:mnp00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    132016358 (GCK)
   00052 Galactose metabolism
    132016358 (GCK)
   00500 Starch and sucrose metabolism
    132016358 (GCK)
  09107 Glycan biosynthesis and metabolism
   00520 Amino sugar and nucleotide sugar metabolism
    132016358 (GCK)
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    132016358 (GCK)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    132016358 (GCK)
   04910 Insulin signaling pathway
    132016358 (GCK)
   04922 Glucagon signaling pathway
    132016358 (GCK)
   04917 Prolactin signaling pathway
    132016358 (GCK)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    132016358 (GCK)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    132016358 (GCK)
   04950 Maturity onset diabetes of the young
    132016358 (GCK)
Enzymes [BR:mnp01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.2  glucokinase
     132016358 (GCK)
SSDB
Motif
Pfam: Hexokinase_2 Hexokinase_1
Other DBs
NCBI-GeneID: 132016358
NCBI-ProteinID: XP_059253576
LinkDB
Position
4:complement(92786911..92806923)
AA seq 544 aa
MGFTAFCSHRLHAGKNPSAIMEAFLSCCPSWPILSPFLQREDGTEPPVYCKRWTYEHTRS
QANPGMNPSHVTHSSNNNPKLPEKQEIQISKKEKAEQILADFQLQEADLKKVMRRMQTEM
ARGLRLQTHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGAEGQWSV
TTKHQMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDK
GILLNWTKGFKASGAEGNNIVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRRCE
VGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRVVDENS
LNPGQQLYEKLIGGKYMGELVRLVLLKLVDENLLFRGEASEQLRTRGAFETRFVSQVESD
SGDRKQIYNILSTLGLRPSATDCDIVRRACESVSTRAAHMCAAGLAGVINRMRESRSEDV
MRITVGVDGSVYKLHPSFKERFHASVRRLTPFCEITFIESEEGSGRGAALISAVACKKAC
MLGQ
NT seq 1635 nt   +upstreamnt  +downstreamnt
atggggttcacagccttttgctcccaccgcctacatgctggcaagaacccctcagccatc
atggaggccttcctaagctgctgccccagctggcccatcctgtccccattcctccagagg
gaggacggcacagagccccccgtctattgcaaaagatggacctacgagcacacccgaagt
caggccaacccgggaatgaaccccagccacgtcacgcacagctccaacaacaaccctaag
ctcccagaaaaacaggaaatacagataagcaaaaaggaaaaggccgagcagatcctggca
gacttccagctgcaggaggcggacctgaagaaggtgatgcggcggatgcagacggagatg
gcgcggggcctgcggctgcagacccacgaggaggccagtgtgaagatgctgcccacctat
gtgcgctccaccccggagggctcagaagtcggggacttcctctccctggacctgggcggc
accaacttcagggtgatgctggtgaaggtgggggagggcgcggaggggcaatggagcgtg
acgaccaagcaccagatgtactccatccccgaggacgctatgaccggcaccgcggagatg
ctgttcgactacatctccgagtgcatctccgacttcctggacaagcatcagatgaagcac
aagaaactgcccttgggcttcacattctccttccccgtgaggcatgaagacatcgacaag
ggcatcctcctcaattggaccaagggcttcaaggcctctggagcagaagggaacaacatc
gtggggctcctccgtgacgccatcaaacggagaggggacttcgaaatggacgtggtagcg
atggtcaacgatacagtggccaccatgatctcctgctactacgaagaccgccggtgtgag
gtcggcatgattgtgggcacaggctgtaacgcctgctacatggaggagatgcagaatgtg
gagctcgtggaaggggacgagggccgcatgtgcgtcaacactgagtggggcgccttcggg
gactctggggagctggacgagttcctgctggagtacgaccgtgtggtggacgagaactcc
ctgaaccccggccagcagctgtacgagaagctcattggcggcaagtacatgggcgagctg
gtgcggctcgtgctgctcaaactcgtggacgaaaacctgcttttccgcggggaggcctcg
gaacagctgcgcacgcgcggcgccttcgagacacgcttcgtgtcgcaggtggagagtgac
tctggcgaccgcaagcagatctacaacatcctgagcacgctggggctgcggccctcggcc
accgactgcgacatcgtgcgccgcgcctgcgagagcgtgtccacgcgcgccgcgcacatg
tgcgctgcggggctggcgggtgtcatcaaccgcatgcgcgagagccgcagcgaggacgtg
atgcgcatcaccgtgggcgtggacggctcggtgtacaagctgcaccccagcttcaaggag
aggttccatgccagcgtacgcaggctgacgcccttctgcgagatcaccttcatcgagtcg
gaggagggcagcggtcggggcgcggcgctgatctccgccgtggcctgcaaaaaggcctgc
atgctgggccagtga

DBGET integrated database retrieval system