KEGG   Mustela nigripes (black-footed ferret): 132016503
Entry
132016503         CDS       T09425                                 
Symbol
PPP3CB
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
mnp  Mustela nigripes (black-footed ferret)
Pathway
mnp04010  MAPK signaling pathway
mnp04020  Calcium signaling pathway
mnp04022  cGMP-PKG signaling pathway
mnp04114  Oocyte meiosis
mnp04218  Cellular senescence
mnp04310  Wnt signaling pathway
mnp04360  Axon guidance
mnp04370  VEGF signaling pathway
mnp04380  Osteoclast differentiation
mnp04625  C-type lectin receptor signaling pathway
mnp04650  Natural killer cell mediated cytotoxicity
mnp04658  Th1 and Th2 cell differentiation
mnp04659  Th17 cell differentiation
mnp04660  T cell receptor signaling pathway
mnp04662  B cell receptor signaling pathway
mnp04720  Long-term potentiation
mnp04724  Glutamatergic synapse
mnp04728  Dopaminergic synapse
mnp04921  Oxytocin signaling pathway
mnp04922  Glucagon signaling pathway
mnp04924  Renin secretion
mnp05010  Alzheimer disease
mnp05014  Amyotrophic lateral sclerosis
mnp05020  Prion disease
mnp05022  Pathways of neurodegeneration - multiple diseases
mnp05031  Amphetamine addiction
mnp05152  Tuberculosis
mnp05163  Human cytomegalovirus infection
mnp05166  Human T-cell leukemia virus 1 infection
mnp05167  Kaposi sarcoma-associated herpesvirus infection
mnp05170  Human immunodeficiency virus 1 infection
mnp05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mnp05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mnp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    132016503 (PPP3CB)
   04310 Wnt signaling pathway
    132016503 (PPP3CB)
   04370 VEGF signaling pathway
    132016503 (PPP3CB)
   04020 Calcium signaling pathway
    132016503 (PPP3CB)
   04022 cGMP-PKG signaling pathway
    132016503 (PPP3CB)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    132016503 (PPP3CB)
   04218 Cellular senescence
    132016503 (PPP3CB)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    132016503 (PPP3CB)
   04650 Natural killer cell mediated cytotoxicity
    132016503 (PPP3CB)
   04660 T cell receptor signaling pathway
    132016503 (PPP3CB)
   04658 Th1 and Th2 cell differentiation
    132016503 (PPP3CB)
   04659 Th17 cell differentiation
    132016503 (PPP3CB)
   04662 B cell receptor signaling pathway
    132016503 (PPP3CB)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    132016503 (PPP3CB)
   04921 Oxytocin signaling pathway
    132016503 (PPP3CB)
   04924 Renin secretion
    132016503 (PPP3CB)
  09156 Nervous system
   04724 Glutamatergic synapse
    132016503 (PPP3CB)
   04728 Dopaminergic synapse
    132016503 (PPP3CB)
   04720 Long-term potentiation
    132016503 (PPP3CB)
  09158 Development and regeneration
   04360 Axon guidance
    132016503 (PPP3CB)
   04380 Osteoclast differentiation
    132016503 (PPP3CB)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    132016503 (PPP3CB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    132016503 (PPP3CB)
   05170 Human immunodeficiency virus 1 infection
    132016503 (PPP3CB)
   05163 Human cytomegalovirus infection
    132016503 (PPP3CB)
   05167 Kaposi sarcoma-associated herpesvirus infection
    132016503 (PPP3CB)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    132016503 (PPP3CB)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    132016503 (PPP3CB)
   05014 Amyotrophic lateral sclerosis
    132016503 (PPP3CB)
   05020 Prion disease
    132016503 (PPP3CB)
   05022 Pathways of neurodegeneration - multiple diseases
    132016503 (PPP3CB)
  09165 Substance dependence
   05031 Amphetamine addiction
    132016503 (PPP3CB)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    132016503 (PPP3CB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mnp01009]
    132016503 (PPP3CB)
Enzymes [BR:mnp01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     132016503 (PPP3CB)
Protein phosphatases and associated proteins [BR:mnp01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     132016503 (PPP3CB)
SSDB
Motif
Pfam: Metallophos DUF5378
Other DBs
NCBI-GeneID: 132016503
NCBI-ProteinID: XP_059253774
LinkDB
Position
4:complement(139379458..139434385)
AA seq 534 aa
MAAPEPARAAPPPPPPPPPPPGADRVVKAVPFPPTHRLTSEEVFDMDGIPRVDVLKNHLV
KEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANT
RYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYS
ERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLL
WSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMY
RKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFT
WSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDERLIYGNKKVGSAAARKEIIRNKIR
AIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGF
SPPHRICSFEEAKGLDRINERMPPRKDAVQQDGFNSLNTAHATENHGTGNHSAQ
NT seq 1605 nt   +upstreamnt  +downstreamnt
atggccgccccggagccggcccgggctgcaccgcccccacccccgcccccgccgccccct
cccggggctgaccgcgtcgtcaaagctgtaccctttcccccaacacatcgcttgacatct
gaagaagtatttgatatggatgggatacccagggttgatgttctgaagaaccacttagta
aaagaaggtcgggtagatgaagaaattgcacttagaattatcaatgagggtgctgccatc
cttcggagagagaaaaccatgatagaagtagaggctccaatcacagtgtgtggtgacatc
catggccaattttttgatctgatgaaactttttgaagtaggaggatcacctgctaataca
cgatacctttttcttggtgattatgtggacagaggttattttagtatagagtgtgtctta
tatttatgggtcctgaagattctgtacccaagcacattatttcttctgcgaggcaatcat
gaatgcagacaccttactgaatattttacctttaagcaggaatgcaaaattaaatattca
gaaagagtctatgaagcttgtatggaagcttttgatagcctgcctctcgctgcactttta
aatcaacaatttctttgtgttcatggtggactttcaccagaaatacacacactggatgat
attaggagattagatagattcaaagagccacctgcatttggaccaatgtgtgacttgcta
tggtccgatccttctgaagattttggaaatgaaaaatcacaggaacattttagtcacaat
acagttcgaggatgttcttatttttataactatccagcagtgtgtgaatttttgcaaaac
aataatttgttatcgattattagagctcatgaagctcaagatgcaggctatagaatgtac
agaaaaagtcaaactacagggttcccttcattaataacaattttttcggcacctaattac
ttagatgtctacaataataaagctgctgtattaaagtatgaaaataatgtgatgaatatt
cgacagtttaactgttctccacatccttactggttgcccaattttatggatgtcttcaca
tggtcattaccatttgttggagaaaaagtgacagaaatgttggtaaatgttctgagtatt
tgctctgatgatgaactgatgactgaaggtgaagaccagtttgatgaacggctcatatat
ggcaataaaaaagtaggttcagctgcagcccggaaagaaatcataagaaacaaaattcga
gcaattggcaagatggcaagggtcttctctgttctcagggaggagagtgaaagtgtgctg
acactcaagggcctgactcccacagggatgttgcctagtggagtgttggctggaggacga
cagaccctgcaaagtgccacagttgaggctattgaggctgaaaaagcaatacgaggattc
tctccaccacatagaatctgcagttttgaagaggcaaagggtttggataggatcaatgag
agaatgccaccccggaaagatgctgtacagcaagatggtttcaattccctgaacaccgca
catgccactgagaaccacgggactggcaaccatagtgcccagtga

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