Mustela nigripes (black-footed ferret): 132017832
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Entry
132017832 CDS
T09425
Symbol
RPS6KB2
Name
(RefSeq) ribosomal protein S6 kinase beta-2 isoform X1
KO
K04688
ribosomal protein S6 kinase beta [EC:
2.7.11.1
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp01521
EGFR tyrosine kinase inhibitor resistance
mnp01522
Endocrine resistance
mnp04012
ErbB signaling pathway
mnp04066
HIF-1 signaling pathway
mnp04140
Autophagy - animal
mnp04150
mTOR signaling pathway
mnp04151
PI3K-Akt signaling pathway
mnp04152
AMPK signaling pathway
mnp04211
Longevity regulating pathway
mnp04213
Longevity regulating pathway - multiple species
mnp04350
TGF-beta signaling pathway
mnp04371
Apelin signaling pathway
mnp04666
Fc gamma R-mediated phagocytosis
mnp04714
Thermogenesis
mnp04910
Insulin signaling pathway
mnp04931
Insulin resistance
mnp05163
Human cytomegalovirus infection
mnp05165
Human papillomavirus infection
mnp05170
Human immunodeficiency virus 1 infection
mnp05200
Pathways in cancer
mnp05205
Proteoglycans in cancer
mnp05207
Chemical carcinogenesis - receptor activation
mnp05210
Colorectal cancer
mnp05212
Pancreatic cancer
mnp05221
Acute myeloid leukemia
mnp05224
Breast cancer
mnp05225
Hepatocellular carcinoma
mnp05226
Gastric cancer
mnp05231
Choline metabolism in cancer
mnp05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
132017832 (RPS6KB2)
04350 TGF-beta signaling pathway
132017832 (RPS6KB2)
04371 Apelin signaling pathway
132017832 (RPS6KB2)
04066 HIF-1 signaling pathway
132017832 (RPS6KB2)
04151 PI3K-Akt signaling pathway
132017832 (RPS6KB2)
04152 AMPK signaling pathway
132017832 (RPS6KB2)
04150 mTOR signaling pathway
132017832 (RPS6KB2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
132017832 (RPS6KB2)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagocytosis
132017832 (RPS6KB2)
09152 Endocrine system
04910 Insulin signaling pathway
132017832 (RPS6KB2)
09149 Aging
04211 Longevity regulating pathway
132017832 (RPS6KB2)
04213 Longevity regulating pathway - multiple species
132017832 (RPS6KB2)
09159 Environmental adaptation
04714 Thermogenesis
132017832 (RPS6KB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
132017832 (RPS6KB2)
05205 Proteoglycans in cancer
132017832 (RPS6KB2)
05207 Chemical carcinogenesis - receptor activation
132017832 (RPS6KB2)
05231 Choline metabolism in cancer
132017832 (RPS6KB2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
132017832 (RPS6KB2)
09162 Cancer: specific types
05210 Colorectal cancer
132017832 (RPS6KB2)
05212 Pancreatic cancer
132017832 (RPS6KB2)
05225 Hepatocellular carcinoma
132017832 (RPS6KB2)
05226 Gastric cancer
132017832 (RPS6KB2)
05221 Acute myeloid leukemia
132017832 (RPS6KB2)
05224 Breast cancer
132017832 (RPS6KB2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
132017832 (RPS6KB2)
05163 Human cytomegalovirus infection
132017832 (RPS6KB2)
05165 Human papillomavirus infection
132017832 (RPS6KB2)
09167 Endocrine and metabolic disease
04931 Insulin resistance
132017832 (RPS6KB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
132017832 (RPS6KB2)
01522 Endocrine resistance
132017832 (RPS6KB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mnp01001
]
132017832 (RPS6KB2)
Enzymes [BR:
mnp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
132017832 (RPS6KB2)
Protein kinases [BR:
mnp01001
]
Serine/threonine kinases: AGC group
RSK family [OT]
132017832 (RPS6KB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_C
Kinase-like
Pkinase_fungal
ABC1
Seadorna_VP7
Motif
Other DBs
NCBI-GeneID:
132017832
NCBI-ProteinID:
XP_059255904
LinkDB
All DBs
Position
1:complement(4981140..4988132)
Genome browser
AA seq
480 aa
AA seq
DB search
MAAVFDLDLETEEGSEGEPESSPSDVCPLAESRAAGLDRPVGRCEEVELTETSVNLGPER
IGPHCFELLRVLGKGGYGKVFQVRKVQGTNSGKIYAMKVLRKAKIVRNAKDTAHTRAERN
ILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLA
LGHLHSQGIIYRDLKPENIMLNSQGHIKLTDFGLCKESIHEDAVTHTFCGTIEYMAPEIL
VRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLALPPYLTPDARDLVK
KFLKRNPSQRIGGGPGDAADVQRHPFFRQINWDDLLACRVDPPIRPSLQSEEDVSQFDTH
FTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFCFQPKLRSPRRLNSSPRTP
VSPLKFSPFEGFRPSSGPLEPTEPSLAPLPPPPPSSSAPLPIRPPSGTKKSKRGRGRPGR
NT seq
1443 nt
NT seq
+upstream
nt +downstream
nt
atggcggccgtgtttgacctggacctggagacggaggaaggcagcgagggtgagccagag
tcgagcccctcggacgtgtgtccccttgccgagtcgagggcggctggcctggataggcct
gtgggacgctgtgaggaggtggagctgaccgagaccagtgtgaacctgggccctgagcgc
atcgggccccactgcttcgagctgctgcgtgtgctgggcaaggggggctatggcaaggtg
ttccaagtgcgaaaggtgcaaggcaccaactcgggcaaaatatatgccatgaaagtcctg
aggaaggccaaaattgtgcgcaacgccaaggacacagcacacacgcgggctgaacggaac
attctagagtcagtgaagcaccccttcattgtggaactggcctatgccttccagactggt
ggcaaactctacctcatcctcgagtgcctcagtggcggtgagctcttcacgcatctggag
cgagagggcatcttcctggaagacacagcctgtttctacttggcggagatcacactggcc
ctgggccacctgcactcccaaggcatcatctaccgggacctcaaacccgagaacatcatg
ctcaacagccagggccacatcaaactgacggacttcggactctgcaaggagtcaatccac
gaggatgcggtcacccacactttctgtggcaccattgagtacatggcccctgagattctg
gtgcgcagtggccacaaccgggcggtggactggtggagcctgggcgccctgatgtatgac
atgctcaccggctcgcctcccttcacggcagagaaccggaagaagacgatggacaagatc
atcaaagggaagctggcgctgcccccctacctcaccccggatgcccgggaccttgtcaaa
aagtttctgaaacggaatcccagccagcggattgggggtggccccggggacgctgctgat
gtgcagaggcaccctttcttccggcaaattaactgggacgacctcctggcttgccgcgtc
gaccctcctatcaggccgtctctgcagtcagaggaggacgtgagccagttcgacacccac
ttcacgcggcagacgccagtggacagtcccgacgacacggccctcagcgagagcgccaac
caggctttcttgggcttcacatatgtggccccctccgtcctggacagcatcaaggagggc
ttctgctttcagcctaagctgcgctcccccaggcgcctcaacagcagcccccggacccca
gtcagccccctgaagttctcgccctttgagggattccggcccagctctggcccactggag
cccacggagccctctctcgcccctctcccaccaccgccaccctcgagctctgctcccctc
cccatccgacccccctcagggaccaagaagtctaagaggggccgtgggcgcccgggacgc
tga
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