KEGG   Mustela nigripes (black-footed ferret): 132017911
Entry
132017911         CDS       T09425                                 
Symbol
PPP1CA
Name
(RefSeq) serine/threonine-protein phosphatase PP1-alpha catalytic subunit
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
mnp  Mustela nigripes (black-footed ferret)
Pathway
mnp03015  mRNA surveillance pathway
mnp04022  cGMP-PKG signaling pathway
mnp04024  cAMP signaling pathway
mnp04114  Oocyte meiosis
mnp04156  Integrated stress response (ISR) signaling pathway
mnp04218  Cellular senescence
mnp04261  Adrenergic signaling in cardiomyocytes
mnp04270  Vascular smooth muscle contraction
mnp04390  Hippo signaling pathway
mnp04510  Focal adhesion
mnp04519  Cadherin signaling
mnp04611  Platelet activation
mnp04720  Long-term potentiation
mnp04728  Dopaminergic synapse
mnp04750  Inflammatory mediator regulation of TRP channels
mnp04810  Regulation of actin cytoskeleton
mnp04910  Insulin signaling pathway
mnp04921  Oxytocin signaling pathway
mnp04931  Insulin resistance
mnp05031  Amphetamine addiction
mnp05034  Alcoholism
mnp05168  Herpes simplex virus 1 infection
mnp05205  Proteoglycans in cancer
mnp05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mnp00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    132017911 (PPP1CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    132017911 (PPP1CA)
   04024 cAMP signaling pathway
    132017911 (PPP1CA)
   04022 cGMP-PKG signaling pathway
    132017911 (PPP1CA)
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    132017911 (PPP1CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    132017911 (PPP1CA)
   04218 Cellular senescence
    132017911 (PPP1CA)
   04156 Integrated stress response (ISR) signaling pathway
    132017911 (PPP1CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    132017911 (PPP1CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    132017911 (PPP1CA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    132017911 (PPP1CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    132017911 (PPP1CA)
   04921 Oxytocin signaling pathway
    132017911 (PPP1CA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    132017911 (PPP1CA)
   04270 Vascular smooth muscle contraction
    132017911 (PPP1CA)
  09156 Nervous system
   04728 Dopaminergic synapse
    132017911 (PPP1CA)
   04720 Long-term potentiation
    132017911 (PPP1CA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    132017911 (PPP1CA)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    132017911 (PPP1CA)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    132017911 (PPP1CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    132017911 (PPP1CA)
   05034 Alcoholism
    132017911 (PPP1CA)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    132017911 (PPP1CA)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    132017911 (PPP1CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mnp01009]
    132017911 (PPP1CA)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:mnp03021]
    132017911 (PPP1CA)
   03019 Messenger RNA biogenesis [BR:mnp03019]
    132017911 (PPP1CA)
   03041 Spliceosome [BR:mnp03041]
    132017911 (PPP1CA)
Enzymes [BR:mnp01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     132017911 (PPP1CA)
Protein phosphatases and associated proteins [BR:mnp01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     132017911 (PPP1CA)
Transcription machinery [BR:mnp03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     132017911 (PPP1CA)
Messenger RNA biogenesis [BR:mnp03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     132017911 (PPP1CA)
Spliceosome [BR:mnp03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    132017911 (PPP1CA)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 132017911
NCBI-ProteinID: XP_059256083
LinkDB
Position
1:5010762..5013735
AA seq 330 aa
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK
NT seq 993 nt   +upstreamnt  +downstreamnt
atgtccgacagcgagaagctcaacctggactctatcatcgggcgcctgctggaagtgcag
ggctcgcggcctggaaagaatgtacagctcacagagaacgagatccgtggtctgtgtctc
aaatcacgggagatcttcttgagccagcccatccttctggagctggaggcacccctcaag
atctgcggtgacatccatggccagtactacgacctcctgcggctatttgagtacggtggc
ttccctccagagagcaactacctcttcctgggggactacgttgaccggggcaagcagtct
ttggagaccatctgcttgctgctggcctataagatcaagtaccccgagaacttcttcctg
ctccgtgggaaccacgagtgtgccagcatcaaccgcatctacggcttctatgatgagtgc
aagagacgctacaacattaaactgtggaaaacctttaccgactgcttcaactgcctgccc
attgctgccatcgtggacgagaagatcttctgctgccacggaggcctgtccccagacttg
cagtccatggaacagattcggcgtatcatgcggcccacagacgtgcctgaccagggcctg
ctgtgtgacctgctgtggtctgatcctgacaaggacgtgcagggctggggcgagaatgac
cgtggtgtctctttcacgtttggggcggaagtggtggccaagttcctgcacaagcacgac
ttggatctcatctgccgggcacaccaggtggtggaagacggctatgagttctttgccaag
cggcagctggtgacactcttctcggctcccaactactgtggcgagtttgacaacgcaggc
gccatgatgagtgtggacgagacgctcatgtgctctttccagatcctcaagcccgcggac
aagaacaaggggaaatacgggcagttcagtggcttgaaccctggaggccggcccatcacc
ccgccccgcaactccgccaaagccaagaaatag

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