KEGG   Mustela nigripes (black-footed ferret): 132019561
Entry
132019561         CDS       T09425                                 
Symbol
KRAS
Name
(RefSeq) GTPase KRas isoform X1
  KO
K07827  GTPase KRas
Organism
mnp  Mustela nigripes (black-footed ferret)
Pathway
mnp01521  EGFR tyrosine kinase inhibitor resistance
mnp01522  Endocrine resistance
mnp04010  MAPK signaling pathway
mnp04012  ErbB signaling pathway
mnp04014  Ras signaling pathway
mnp04015  Rap1 signaling pathway
mnp04062  Chemokine signaling pathway
mnp04068  FoxO signaling pathway
mnp04071  Sphingolipid signaling pathway
mnp04072  Phospholipase D signaling pathway
mnp04137  Mitophagy - animal
mnp04140  Autophagy - animal
mnp04150  mTOR signaling pathway
mnp04151  PI3K-Akt signaling pathway
mnp04210  Apoptosis
mnp04211  Longevity regulating pathway
mnp04213  Longevity regulating pathway - multiple species
mnp04218  Cellular senescence
mnp04360  Axon guidance
mnp04370  VEGF signaling pathway
mnp04371  Apelin signaling pathway
mnp04540  Gap junction
mnp04550  Signaling pathways regulating pluripotency of stem cells
mnp04625  C-type lectin receptor signaling pathway
mnp04650  Natural killer cell mediated cytotoxicity
mnp04660  T cell receptor signaling pathway
mnp04662  B cell receptor signaling pathway
mnp04664  Fc epsilon RI signaling pathway
mnp04714  Thermogenesis
mnp04720  Long-term potentiation
mnp04722  Neurotrophin signaling pathway
mnp04725  Cholinergic synapse
mnp04726  Serotonergic synapse
mnp04730  Long-term depression
mnp04810  Regulation of actin cytoskeleton
mnp04910  Insulin signaling pathway
mnp04912  GnRH signaling pathway
mnp04914  Progesterone-mediated oocyte maturation
mnp04915  Estrogen signaling pathway
mnp04916  Melanogenesis
mnp04917  Prolactin signaling pathway
mnp04919  Thyroid hormone signaling pathway
mnp04921  Oxytocin signaling pathway
mnp04926  Relaxin signaling pathway
mnp04929  GnRH secretion
mnp04933  AGE-RAGE signaling pathway in diabetic complications
mnp04935  Growth hormone synthesis, secretion and action
mnp04960  Aldosterone-regulated sodium reabsorption
mnp05010  Alzheimer disease
mnp05022  Pathways of neurodegeneration - multiple diseases
mnp05034  Alcoholism
mnp05160  Hepatitis C
mnp05161  Hepatitis B
mnp05163  Human cytomegalovirus infection
mnp05165  Human papillomavirus infection
mnp05166  Human T-cell leukemia virus 1 infection
mnp05167  Kaposi sarcoma-associated herpesvirus infection
mnp05170  Human immunodeficiency virus 1 infection
mnp05200  Pathways in cancer
mnp05203  Viral carcinogenesis
mnp05205  Proteoglycans in cancer
mnp05206  MicroRNAs in cancer
mnp05207  Chemical carcinogenesis - receptor activation
mnp05208  Chemical carcinogenesis - reactive oxygen species
mnp05210  Colorectal cancer
mnp05211  Renal cell carcinoma
mnp05212  Pancreatic cancer
mnp05213  Endometrial cancer
mnp05214  Glioma
mnp05215  Prostate cancer
mnp05216  Thyroid cancer
mnp05218  Melanoma
mnp05219  Bladder cancer
mnp05220  Chronic myeloid leukemia
mnp05221  Acute myeloid leukemia
mnp05223  Non-small cell lung cancer
mnp05224  Breast cancer
mnp05225  Hepatocellular carcinoma
mnp05226  Gastric cancer
mnp05230  Central carbon metabolism in cancer
mnp05231  Choline metabolism in cancer
mnp05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mnp05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mnp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    132019561 (KRAS)
   04012 ErbB signaling pathway
    132019561 (KRAS)
   04014 Ras signaling pathway
    132019561 (KRAS)
   04015 Rap1 signaling pathway
    132019561 (KRAS)
   04370 VEGF signaling pathway
    132019561 (KRAS)
   04371 Apelin signaling pathway
    132019561 (KRAS)
   04068 FoxO signaling pathway
    132019561 (KRAS)
   04072 Phospholipase D signaling pathway
    132019561 (KRAS)
   04071 Sphingolipid signaling pathway
    132019561 (KRAS)
   04151 PI3K-Akt signaling pathway
    132019561 (KRAS)
   04150 mTOR signaling pathway
    132019561 (KRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    132019561 (KRAS)
   04137 Mitophagy - animal
    132019561 (KRAS)
  09143 Cell growth and death
   04210 Apoptosis
    132019561 (KRAS)
   04218 Cellular senescence
    132019561 (KRAS)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    132019561 (KRAS)
   04550 Signaling pathways regulating pluripotency of stem cells
    132019561 (KRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    132019561 (KRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    132019561 (KRAS)
   04650 Natural killer cell mediated cytotoxicity
    132019561 (KRAS)
   04660 T cell receptor signaling pathway
    132019561 (KRAS)
   04662 B cell receptor signaling pathway
    132019561 (KRAS)
   04664 Fc epsilon RI signaling pathway
    132019561 (KRAS)
   04062 Chemokine signaling pathway
    132019561 (KRAS)
  09152 Endocrine system
   04910 Insulin signaling pathway
    132019561 (KRAS)
   04929 GnRH secretion
    132019561 (KRAS)
   04912 GnRH signaling pathway
    132019561 (KRAS)
   04915 Estrogen signaling pathway
    132019561 (KRAS)
   04914 Progesterone-mediated oocyte maturation
    132019561 (KRAS)
   04917 Prolactin signaling pathway
    132019561 (KRAS)
   04921 Oxytocin signaling pathway
    132019561 (KRAS)
   04926 Relaxin signaling pathway
    132019561 (KRAS)
   04935 Growth hormone synthesis, secretion and action
    132019561 (KRAS)
   04919 Thyroid hormone signaling pathway
    132019561 (KRAS)
   04916 Melanogenesis
    132019561 (KRAS)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    132019561 (KRAS)
  09156 Nervous system
   04725 Cholinergic synapse
    132019561 (KRAS)
   04726 Serotonergic synapse
    132019561 (KRAS)
   04720 Long-term potentiation
    132019561 (KRAS)
   04730 Long-term depression
    132019561 (KRAS)
   04722 Neurotrophin signaling pathway
    132019561 (KRAS)
  09158 Development and regeneration
   04360 Axon guidance
    132019561 (KRAS)
  09149 Aging
   04211 Longevity regulating pathway
    132019561 (KRAS)
   04213 Longevity regulating pathway - multiple species
    132019561 (KRAS)
  09159 Environmental adaptation
   04714 Thermogenesis
    132019561 (KRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    132019561 (KRAS)
   05206 MicroRNAs in cancer
    132019561 (KRAS)
   05205 Proteoglycans in cancer
    132019561 (KRAS)
   05207 Chemical carcinogenesis - receptor activation
    132019561 (KRAS)
   05208 Chemical carcinogenesis - reactive oxygen species
    132019561 (KRAS)
   05203 Viral carcinogenesis
    132019561 (KRAS)
   05230 Central carbon metabolism in cancer
    132019561 (KRAS)
   05231 Choline metabolism in cancer
    132019561 (KRAS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    132019561 (KRAS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    132019561 (KRAS)
   05212 Pancreatic cancer
    132019561 (KRAS)
   05225 Hepatocellular carcinoma
    132019561 (KRAS)
   05226 Gastric cancer
    132019561 (KRAS)
   05214 Glioma
    132019561 (KRAS)
   05216 Thyroid cancer
    132019561 (KRAS)
   05221 Acute myeloid leukemia
    132019561 (KRAS)
   05220 Chronic myeloid leukemia
    132019561 (KRAS)
   05218 Melanoma
    132019561 (KRAS)
   05211 Renal cell carcinoma
    132019561 (KRAS)
   05219 Bladder cancer
    132019561 (KRAS)
   05215 Prostate cancer
    132019561 (KRAS)
   05213 Endometrial cancer
    132019561 (KRAS)
   05224 Breast cancer
    132019561 (KRAS)
   05223 Non-small cell lung cancer
    132019561 (KRAS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    132019561 (KRAS)
   05170 Human immunodeficiency virus 1 infection
    132019561 (KRAS)
   05161 Hepatitis B
    132019561 (KRAS)
   05160 Hepatitis C
    132019561 (KRAS)
   05163 Human cytomegalovirus infection
    132019561 (KRAS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    132019561 (KRAS)
   05165 Human papillomavirus infection
    132019561 (KRAS)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    132019561 (KRAS)
   05022 Pathways of neurodegeneration - multiple diseases
    132019561 (KRAS)
  09165 Substance dependence
   05034 Alcoholism
    132019561 (KRAS)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    132019561 (KRAS)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    132019561 (KRAS)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    132019561 (KRAS)
   01522 Endocrine resistance
    132019561 (KRAS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mnp04131]
    132019561 (KRAS)
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:mnp04031]
    132019561 (KRAS)
Membrane trafficking [BR:mnp04131]
 Endocytosis
  Macropinocytosis
   Ras GTPases
    132019561 (KRAS)
GTP-binding proteins [BR:mnp04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    132019561 (KRAS)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase G-alpha ATP_bind_1 FeoB_N Septin DUF6974
Other DBs
NCBI-GeneID: 132019561
NCBI-ProteinID: XP_059258760
LinkDB
Position
6:68867974..68907050
AA seq 189 aa
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL
PSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKINKEEKTPGC
VKIKKCIVM
NT seq 570 nt   +upstreamnt  +downstreamnt
atgactgaatataaacttgtggtagttggagctggtggcgtaggcaagagtgccttgacg
atacagctaattcagaatcactttgtggatgagtatgatcctacaatagaggattcctac
aggaaacaagtagtaattgatggagaaacctgtctgttggatattctcgacacagcaggt
caagaggagtacagtgcaatgagggaccagtacatgaggactggggagggctttctttgt
gtatttgccataaataatactaaatcatttgaagatattcaccattatagagaacaaata
aaaagagttaaagactctgaagatgtacctatggtcctagtaggaaataaatgtgatttg
ccttctagaacagtagacacaaaacaggctcaggacttagcaagaagttatggaattcct
tttattgaaacatcagcaaagacaagacagagagtggaggatgctttttatacattggtg
agagagatccgacaatacagattgaaaaaaatcaacaaagaagaaaagactcctggctgt
gtgaaaattaaaaaatgcattgtaatgtaa

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