Mustela nigripes (black-footed ferret): 132021091
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Entry
132021091 CDS
T09425
Symbol
TPO
Name
(RefSeq) thyroid peroxidase isoform X1
KO
K00431
thyroid peroxidase [EC:
1.11.1.8
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp00350
Tyrosine metabolism
mnp01100
Metabolic pathways
mnp04918
Thyroid hormone synthesis
mnp05320
Autoimmune thyroid disease
Module
mnp_M00043
Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
132021091 (TPO)
09150 Organismal Systems
09152 Endocrine system
04918 Thyroid hormone synthesis
132021091 (TPO)
09160 Human Diseases
09163 Immune disease
05320 Autoimmune thyroid disease
132021091 (TPO)
Enzymes [BR:
mnp01000
]
1. Oxidoreductases
1.11 Acting on a peroxide as acceptor
1.11.1 Peroxidases
1.11.1.8 iodide peroxidase
132021091 (TPO)
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Gene cluster
GFIT
Motif
Pfam:
An_peroxidase
EGF_CA
EGF_3
cEGF
FXa_inhibition
EGF
Motif
Other DBs
NCBI-GeneID:
132021091
NCBI-ProteinID:
XP_059261042
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Position
7:457277..504707
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AA seq
937 aa
AA seq
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MGRLFSAGSAVRRRALAVLGVTLAAACAHGLFPFLRRGQDLLWGRSGDPPVLSVVEETRR
MVDRAIYHTVKRDLRQRGVPSPSQLLSFSKRPEPTSRAVSRAAEIMEASVQALKTRVSGK
LRRSWPPTDVLPEDVLNTVANVSGCLPYMLPPECPDTCLADKYRLITGACNNRDHPRWGA
SNTALARWLPPAYEDGISQPRGWNPHFLYSGFPLPPVREVTRQVIQVPNEAVTEDEQYSD
LLAAWGQYIDHDIAFTPQSTSKAAFGGGADCQLTCENQNPCFPIQLPSNASGSASISCLP
FYRSSAACGTGMQGAFFGNLSSANPRQQMNGLTSFLDASTVYGSSPALEKQLRNWTSAEG
LLRVNTRHRDAGRAYLPFAQLTTCAPEPGPHGTTAAPCFLAGDSRASEVPALTALHTLWL
REHNRLASALKALNAHWSAHTAYQEARKVVGALHQIITMRDYVPKVLGPEAFQKHVGPYE
GYDPAVDPTVSNVFSTAAFRFGHATVHPLVRRLDADYQEPPGLPPLRLRDAFFRPWRLLK
EGGLDPLVRGLLARPAKRQVPEQLMNEELTERLFVLGSSDGLDLASINLQRGRDHGLPGY
NAWREFCGLPRLQTRADLHAAFANASIAGRILDLYGHPDNIDVWLGGLAETFLPQARTGP
LFACLIGRQMKALRDGDRFWWESSGVFTEAQRRALARHSLSRVLCDNTGLPRVPADAFRT
GRFPRDFEACENIPGLNLDVWREPPPQGDACGLPDGVDNGDVVLCGETGRRVLVFSCRHG
FQLQGREQVACAPRGLLRPPVCRDVNECEDATAPPCHPSARCRNTKGGFRCECTDPYVLA
EDGTACVDSGRLPKASWVSIALGALLVGGLAGLTWTVVCRWAHAGRKASLCIADSGGRGT
CQPGLRTRWDSNASQPAAATRGAGQDPACGSQILLCQ
NT seq
2814 nt
NT seq
+upstream
nt +downstream
nt
atgggccgcttgttctcagccggttccgccgtcagaaggagagcacttgccgtcctgggc
gtcacgctggcggcggcctgtgcccatggcctcttccccttcctccggagaggccaggac
ctcctgtggggacggagcggagaccctcctgtgctcagcgtcgtggaggagaccagacgc
atggtggaccgcgccatctaccacaccgtgaagagagacctccgccaaagaggggtcccg
tctccgtcacagcttctgtctttctccaaacgccctgagccgaccagccgcgccgtctcc
cgtgcggccgagatcatggaagcctccgtgcaggccctgaagacaagagtctccgggaag
ctccggagatcctggcctcccaccgatgtcctgccagaagacgtgctgaacacagtcgcg
aacgtgtccggatgcttgccctacatgctgcccccagagtgcccagacacctgcctggcc
gacaagtaccggctcatcacgggcgcctgcaacaacagagaccacccccggtggggggcg
tccaacacggcgctggcgagatggctgcccccggcctacgaagacggcatcagccagccc
cgggggtggaacccccacttcctgtacagcggcttcccgctgcccccggtccgggaggtg
acaagacaagtcattcaggtccccaacgaggccgtcactgaggacgagcagtactccgac
ctcctggcagcgtggggacaatacattgaccatgacattgcgttcaccccccagagcacc
agcaaagctgcgtttgggggaggggctgactgccagctgacgtgtgaaaaccagaaccca
tgtttccccatacagctgcccagcaacgcctcggggagcgccagcatctcctgtttgccg
ttctaccggtcctctgctgcctgtggcaccgggatgcagggcgccttcttcgggaacctg
agctcggccaacccgcgacagcagatgaacgggctgacgtctttcctggacgcgtccacg
gtgtatggcagctccccagccttggagaaacagctgcgcaactggacgagtgccgagggg
ctgctccgggtcaacacgcgccaccgggacgccggccgcgcctacctgcccttcgcgcaa
ctcactacctgcgcgcctgagcccggcccccacgggacgaccgctgcgccctgcttcctg
gcgggggacagccgagccagcgaggtgcccgctctcacggccctgcacacgctgtggctg
cgcgagcacaaccggctggcctcggcgctcaaggctctgaacgcgcactggagcgcccac
acggcctaccaggaggcgcgcaaggtggtgggcgccctgcaccagatcatcaccatgcgg
gattatgtccccaaagtcctgggccccgaggccttccagaagcacgtgggcccttatgag
ggctacgaccctgccgtggaccccaccgtgtccaatgtgttttctacggctgccttccgc
tttggccacgccaccgtgcaccccctggtgaggcggctggacgccgactaccaggagccc
ccgggcctccccccgctgcggctacgggacgccttcttccgtccctggaggctcctcaag
gaagggggtctggaccccctggtgaggggcctcctggcgagaccagccaagcggcaggtg
ccggagcagctgatgaacgaggagctgacggagaggctgttcgtgctgggcagctcggac
gggctggacctggcgtccatcaacctgcagcggggccgggaccacggcctgccaggctac
aacgcatggagggagttctgcggcctgcccagactgcagacacgggctgacctgcacgcc
gccttcgccaacgccagcatcgcgggccggatattggacctgtacgggcaccccgacaac
atcgacgtctggctgggcggcctggccgagaccttcctgccccaggcgcgcacgggcccg
ctgttcgcgtgcctcatcgggagacagatgaaggccctgagggacggagaccggttctgg
tgggagagcagcggggtgttcaccgaggcccagcggcgcgcgctggccagacattccctg
tcccgggtcctctgtgacaacacgggcctcccccgcgtgcctgcggatgccttccgaacc
gggagattcccgcgggactttgaggcgtgcgagaacattccggggctgaacctggacgtg
tggagggagccccctcctcaaggtgacgcgtgtggcctccccgacggcgtggacaacggg
gacgttgtgctctgcggcgagaccggacggcgcgtgctcgtgttctcctgccgccacggg
ttccagctgcagggccgggagcaggtggcttgtgccccccgcggcctgctccggccgccc
gtgtgccgagacgtcaacgagtgtgaagacgcgacggcccctccctgccacccatcggcc
cggtgcaggaacaccaagggtggcttccgctgcgagtgcacagacccctacgtgctggcg
gaggacgggacggcgtgcgtagactctgggaggctcccgaaggcgtcctgggtctccatc
gccttgggcgccctgctggtcggcggcctggcgggtctcacctggacagtggtttgcagg
tgggcacacgccggccggaaagcctcgctgtgcatcgcagactcgggtggaagaggaacc
tgccagccgggtctcagaacgcgctgggactcgaacgcgtcacagcctgctgccgccact
cggggtgcaggccaggacccggcctgtggatcccaaatccttctctgccagtag
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