Mustela nigripes (black-footed ferret): 132022989
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Entry
132022989 CDS
T09425
Symbol
NPC1
Name
(RefSeq) NPC intracellular cholesterol transporter 1
KO
K12385
Niemann-Pick C1 protein
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp03265
Virion - Ebolavirus, Lyssavirus and Morbillivirus
mnp04142
Lysosome
mnp04979
Cholesterol metabolism
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09120 Genetic Information Processing
09125 Information processing in viruses
03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
132022989 (NPC1)
09140 Cellular Processes
09141 Transport and catabolism
04142 Lysosome
132022989 (NPC1)
09150 Organismal Systems
09154 Digestive system
04979 Cholesterol metabolism
132022989 (NPC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
mnp02000
]
132022989 (NPC1)
Transporters [BR:
mnp02000
]
Solute carrier family (SLC)
SLC65: NPC-type cholesterol transporter
132022989 (NPC1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NPC1_MLD
NPC1_N
Sterol-sensing
Patched
MMPL
ACR_tran
Folate_rec
Motif
Other DBs
NCBI-GeneID:
132022989
NCBI-ProteinID:
XP_059264043
LinkDB
All DBs
Position
8:complement(44508581..44556623)
Genome browser
AA seq
1419 aa
AA seq
DB search
MPHTFGTTPAISSQPGSRSSAAPVWDPYRKSHPQNHRAAKRRADPAEEAPPKGRCPVRPR
PRPAPPSPGRPRPRTGPGRPVSGTAQKGEEPTTPSSFLLHARSPPPASAPSLGWHGILRQ
PCAPSRGEPSRVPPLSAARHRGSMTARGPALGLLLLLLCPAQVLAQSCVWYGECGIASGD
KRYNCQYSGPPKPLPKDGYDLMQELCPGFFFDNVSVCCDVQQLRTLKDSLQLPLQFLSRC
PSCFYNLMNLFCELTCSPQQSQFLNVTETEDYVDPVTNQTKTNVKELQYYVGESFANAMY
NACRDVEAPSSNDKALGLLCGKDAGACNATNWIEYMFNKDNGQAPFTITPIFSDLPAHGM
EPMNNATKGCDESVDEVTGPCSCQDCSAVCGPRPQPPPPPAPWRILGLDAMYVIMWTTYM
AFLLVFFGAVFAVWCYRKRYFVSEYTPIDSNIAFSVNASDKGEASCCDALGAAFEGWLRQ
LFSHWGSFCVRNPGCIVVFSLAFIAACSSGLVFFRVTTNPVDLWSAPGSQARLEKEYFDT
HFGPFFRTEQLIIQAPHTPVHTYQPYPSGSDVPFGPPLDRGILHQVLDLQTAIENITAFY
NNETVTLQDICVAPLSPYNKNCTIMSVLNYFQNSHSVLDHEVGDDFFVYADYHTHLLYCV
RAPASLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTEKL
QRAQAWEKEFINFVKNYENPNLTISFTTERSIEDELNRESNGDVFTVLISYAVMFLYISI
ALGHIKSWSRFLVDSKISLGIAGILIVLSSVACSLGIFSYVGIPLTLIVIEVIPFLVLAV
GVDNIFILVQTYQRDERLQGETLDQQLGRVLGEVAPSMFLSSFSEAVAFFLGALSKMPAV
HTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKHRLDVLCCVRGSEDGTSVQTSESCL
FRFFKNSYSPLLLKDWMRPIVIAVFVGVLSFSIAVLNKVEIGLDQSLSMPDDSYVLDYFR
SLRYLHAGPPVYFVLEEGHDYSSLKGQNMVCGGMGCNNDSLVQQIFTAAQLDNYTRIGFA
PSSWIDDYFDWVKPQSSCCRVYNGTDRFCNASVVDPACGRCRPLTPEGKQRPQGEDFMRF
LPMFLSDNPNPKCGKGGHAAYSSAVNILGNDTAVGATYFMTYHTVLQTSADFTDAMRKAI
LIAGNITKTMGLEGSGYRVFPYSVFYVFYEQYLTIIDDTIFNLSVSLGAIFLVTLVLLGC
ELWSAVIMCVTIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVST
KGSRVERAEEALSHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATH
GLIFLPVLLSYIGPSINKAKSLATQERYKGTEREQLLNF
NT seq
4260 nt
NT seq
+upstream
nt +downstream
nt
atgccacacactttcggcacaactccagcaatatcctcccagccgggttccagaagttcg
gctgccccagtctgggatccctaccgtaagtcgcacccccaaaaccacagggccgcaaaa
cgcagagctgaccctgcagaggaagccccgccaaaggggcgctgcccagtcaggccccgc
ccccgccccgccccgccttccccgggtcggccccgccccagaacgggtcccgggcgtccc
gtcagcggcaccgcccagaaaggggaggagccgacgacgccttcctctttcctgctccac
gctcgtagtccgccgccggcgtctgctccctccctaggctggcacggcatcctgaggcag
ccctgcgcgccgagccggggcgagcccagccgagtcccgccgctgtccgcagcccggcac
cgcggcagcatgaccgcgcgcggcccagcgctcggcctcctcctgctgctgctctgtccc
gcgcaggtgttggcacagtcctgtgtgtggtatggagagtgtggaattgcatctggagac
aagaggtacaactgccaatactcggggccaccaaaacccttgccgaaggacgggtatgac
ttaatgcaggagctctgcccgggcttcttctttgacaacgtcagcgtgtgctgcgacgtg
cagcagctgcggaccctgaaggatagcctgcagctgcccctgcagtttctgtccagatgt
ccatcctgtttttataacctaatgaacctgttttgcgagctgacgtgtagcccccagcaa
agtcagtttctgaatgttacagaaactgaagattatgtagatcctgttacaaaccagacg
aaaacaaacgtaaaagaattacagtactatgttggagagagttttgccaatgccatgtac
aacgcctgccgggacgtggaggccccctccagtaatgacaaagccctggggctcctgtgt
gggaaggacgccggggcctgcaacgccaccaactggatcgagtacatgttcaataaggac
aacggccaggcgccttttaccatcacgcccattttctcagatcttccggcccatgggatg
gagcccatgaacaacgccaccaagggctgtgatgagtctgtggatgaggtcacggggccg
tgcagctgccaagactgctcggccgtgtgtggccccaggccccagccgccaccccctccg
gctccctggagaatcttgggcctggacgccatgtacgtcatcatgtggaccacctacatg
gcgttcttgcttgtcttctttggagcagtatttgccgtgtggtgctacagaaaacgctat
tttgtctctgagtacacccccattgacagcaatattgctttctccgtaaatgccagtgac
aaaggggaggcgtcctgctgtgatgcgcttggggcggcattcgagggctggctgaggcag
ctcttctcccactggggctccttctgcgtccgcaacccgggctgcatcgtcgtcttctcc
ctggccttcatcgccgcctgctcgtcaggcctggtgttcttccgggtcacgaccaacccg
gtggatttgtggtcggcccccggcagccaggcgcgcctggagaaagagtattttgacacg
cattttgggcccttcttccgcacggagcagctcatcatccaggctccccacaccccggtg
cacacgtaccagccgtacccctctggctccgatgtgcccttcggacccccgctcgacaga
gggatcttgcaccaggttctcgacttacaaaccgccattgaaaacatcactgccttttac
aacaacgagaccgtgacacttcaggacatctgcgtagccccactctcaccctataacaag
aactgcaccatcatgagtgtgttgaattacttccagaacagccattccgtgctggaccac
gaagtaggcgatgacttcttcgtgtacgcagattaccacacgcacttgctgtactgcgta
cgggctcctgcctctctgaatgataccagtttgctccatgacccttgcctgggtacgttt
ggtgggccagtgttcccgtggcttgtgttaggaggctatgatgatcaaaactacaataac
gctacagcccttgtgattacctttcctgtcaataattactacaatgatacagagaagctc
cagagggcccaggcctgggagaaagagtttattaattttgtgaaaaactacgagaatcca
aatctgaccatttctttcacgactgagcgaagtattgaggatgaactgaatcgtgagagt
aacggtgatgtctttactgtcctgatcagctacgccgtcatgtttctgtacatttccata
gccttgggccacatcaaaagctggagcaggtttctagtggattctaaaatctcccttggc
atcgctgggatcctcatcgtgttgagctcagtggcgtgctcactgggcatcttcagctac
gttgggatccccctcaccctcattgtgatcgaagtcatcccattcctggtgctggctgtc
ggggtggacaacatcttcattctggtccagacctaccagcgagatgaacgtcttcaagga
gaaactctggatcagcagctgggcagggtcctaggagaagtggctcctagtatgttcctg
tcctccttttcagaggctgtagcgtttttcttaggggcgctgtcaaagatgccagccgtt
cacactttctccctgttcgccgggatggccgtcctcattgacttccttcttcagatcaca
tgttttgtgagtctcttggggttagacatcaagcgtcaagagaaacatcgtctggatgtc
ctttgctgtgtcagaggctctgaagatggaactagtgtccagacctcagaaagctgcctg
tttcggttcttcaaaaactcctattctccacttctgcttaaggattggatgcgacctatt
gtgatagcggtatttgtgggtgtcctgtccttcagtattgcggtgctgaacaaagtggaa
attggattggatcagtctctctccatgcccgatgactcctacgtgctggattacttcagg
tcgctcagatacctgcatgcgggcccacctgtgtacttcgtcctggaggaagggcacgac
tacagctccctgaaagggcagaacatggtgtgcgggggcatgggctgcaataacgactcc
ctggtgcaacagatcttcaccgcggctcagctggacaactatacccgaataggctttgcc
ccctcgtcctggatcgatgattattttgattgggtcaagcctcagtcttcttgctgtaga
gtctacaacggcacggatcgcttctgcaatgcctcagtggttgaccctgcctgtggccgc
tgcagacctctaaccccagagggcaaacagaggcctcaaggggaagacttcatgagattc
ctgcccatgttcctttctgataacccgaaccccaagtgcggcaaagggggacatgctgct
tacagttcagccgttaacatcctcggcaatgacacagctgtcggcgccacatacttcatg
acctaccacactgtgcttcagacctctgctgactttactgatgccatgagaaaagccatc
ctcattgccggcaacatcaccaaaaccatgggcctcgaaggaagcggttaccgtgtgttc
ccgtacagtgtgttctatgtcttctacgaacagtacctgaccattatcgatgacacgatc
tttaatctcagtgtgtccctgggagccatcttcttggtgaccctggttctcctgggctgt
gaactgtggtctgcagtgatcatgtgtgtcaccatcgccatgatcttggtcaacatgttt
ggcgtcatgtggctctggggcatcagtctgaatgcagtttccttggtcaatttggttatg
agctgtggcatttccgtggagttctgtagccacatcacaagagcgttcacagtgagcacg
aagggcagccgcgtggaacgggccgaagaggcgctctctcacatgggcagctccgtgttc
agtggaatcacactaacaaaatttggagggattgtggtgctggcgtttgccaagtctcag
atcttccagatattctacttcaggatgtatctggctatggtcttactgggagccacccat
ggcttgatattcctccctgtcttactcagctacataggcccatccataaataaagccaaa
agtttggccactcaagagcgatacaaaggtacagagcgagaacagctcctaaatttctag
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