Mustela nigripes (black-footed ferret): 132023139
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Entry
132023139 CDS
T09425
Symbol
ATP2A2
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp04020
Calcium signaling pathway
mnp04022
cGMP-PKG signaling pathway
mnp04024
cAMP signaling pathway
mnp04148
Efferocytosis
mnp04260
Cardiac muscle contraction
mnp04261
Adrenergic signaling in cardiomyocytes
mnp04380
Osteoclast differentiation
mnp04919
Thyroid hormone signaling pathway
mnp04972
Pancreatic secretion
mnp05010
Alzheimer disease
mnp05017
Spinocerebellar ataxia
mnp05022
Pathways of neurodegeneration - multiple diseases
mnp05410
Hypertrophic cardiomyopathy
mnp05412
Arrhythmogenic right ventricular cardiomyopathy
mnp05414
Dilated cardiomyopathy
mnp05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
132023139 (ATP2A2)
04024 cAMP signaling pathway
132023139 (ATP2A2)
04022 cGMP-PKG signaling pathway
132023139 (ATP2A2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
132023139 (ATP2A2)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
132023139 (ATP2A2)
09153 Circulatory system
04260 Cardiac muscle contraction
132023139 (ATP2A2)
04261 Adrenergic signaling in cardiomyocytes
132023139 (ATP2A2)
09154 Digestive system
04972 Pancreatic secretion
132023139 (ATP2A2)
09158 Development and regeneration
04380 Osteoclast differentiation
132023139 (ATP2A2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
132023139 (ATP2A2)
05017 Spinocerebellar ataxia
132023139 (ATP2A2)
05022 Pathways of neurodegeneration - multiple diseases
132023139 (ATP2A2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
132023139 (ATP2A2)
05412 Arrhythmogenic right ventricular cardiomyopathy
132023139 (ATP2A2)
05414 Dilated cardiomyopathy
132023139 (ATP2A2)
05415 Diabetic cardiomyopathy
132023139 (ATP2A2)
Enzymes [BR:
mnp01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
132023139 (ATP2A2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Cation_ATPase
Cation_ATPase_C
E1-E2_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
132023139
NCBI-ProteinID:
XP_059264375
LinkDB
All DBs
Position
8:7849285..7909402
Genome browser
AA seq
1042 aa
AA seq
DB search
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKEKWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDKVEGDSCSLNEFTITGSTYAPIGEVHKDDKPVKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGV
KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMNLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL
NPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKDDNPDFEGVDCAIFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNLTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSLSACTDGISWPFVL
LIMPLVVWVYSTDTNFSDMFWS
NT seq
3129 nt
NT seq
+upstream
nt +downstream
nt
atggagaacgcgcacacaaagacggtggaggaggtgctgggccacttcggcgtcaacgag
agcacggggctgagcctggagcaggtcaagaagctcaaggagaaatggggttccaacgag
ttaccggctgaagaaggaaaaaccttgctggaacttgtgattgagcagtttgaagactta
ctagttagaattttattgctggcagcttgtatatcttttgttttggcttggtttgaagaa
ggtgaagaaacaataacagcctttgtagaaccctttgtaattttacttatattagtggcc
aatgcaattgtgggtgtatggcaggaaagaaatgctgagaatgcaatcgaagcccttaag
gaatatgagcctgaaatgggcaaagtataccgacaggacagaaagagtgtccagcggatt
aaagctaaagacatagttcctggtgatattgtagaaattgctgttggtgacaaagttcct
gctgatataagattaacttccatcaaatctactactctaagagttgaccagtctattctc
acaggcgagtctgtgtccgtcatcaagcacacagaccccgtcccagacccgcgggccgtc
aaccaagataagaagaacatgctcttttctggtacaaacattgctgctggcaaagccatg
ggagtggtggtggcaactggagtgaacacagaaattggcaagatccgggatgagatggtg
gcgacagagcaggagagaaccccgctccagcagaaactagatgagtttggggaacagctt
tccaaagtcatctccctcatttgcattgcggtctggatcataaacattgggcacttcaac
gacccagttcatggaggctcctggatcaggggtgctatttactacttcaaaattgcggtg
gctctggctgtggcagccattcctgaaggtctgcctgctgtcatcaccacctgcctggct
cttggaactcgcagaatggcaaagaaaaatgccattgttcgaagcctcccttctgtagaa
acccttggttgtacttctgttatctgctcagacaagactggtacgctgacaacaaaccag
atgtctgtgtgcaggatgttcattctggacaaagttgaaggtgatagctgttcccttaat
gagtttaccattactggatcaacttatgcacctattggagaagtgcataaagatgataaa
ccagttaaatgtcatcaatatgatggtcttgtggaattggcaacaatttgtgctctttgt
aatgattctgcgttggattacaatgaggcaaagggtgtatatgaaaaagttggagaagct
acagagactgctctcacttgcctagtagagaagatgaatgtatttgatactgaattgaag
ggtctttctaaaatagagcgagcaaatgcctgcaactcggtcatcaagcagttgatgaaa
aaggaatttactctggagttttcacgtgacagaaaatcgatgtcagtttattgtacgcca
aacaaaccgagccggacatcgatgagcaaaatgtttgtgaagggtgcccccgaaggtgtc
attgacaggtgcacccacattcgagttggcagtactaaagttcctatgaccccgggagtc
aaacagaagatcatgtctgtcattcgggaatggggtagtggcagcgacacactgcggtgc
ctggctctggccactcacgacaacccactgagaagagaagaaatgaaccttgaggactct
gccaactttattaaatacgagaccaatctgactttcgttggctgcgtgggcatgctggac
cctccaagaattgaagtggcctcttccgtgaagctgtgccggcaagcaggcatccgggtc
atcatgatcacgggggacaacaagggcactgcagtggccatctgtcggcgcattggcatc
ttcgggcaggacgaggatgtgacgtcaaaggcttttaccggtcgggagtttgatgagctc
aatccttcagcccaaagagatgcctgtttgaatgctcgctgtttcgctcgagtcgaacct
tcccacaagtcaaaaattgtagaatttcttcagtcttttgatgagattacagctatgact
ggggacggcgtgaatgatgctcccgccctgaagaaatcggagatcggcattgccatgggc
tctggcacggcggtggccaaaacagcctcagagatggtgctggccgacgacaacttctcc
accatcgtggctgcggtggaggaggggcgcgccatctacaacaacatgaagcagttcatc
cgctatctcatctcctcgaatgtgggggaagtggtctgtatcttcctgacagcagccctt
ggatttcctgaggctttaattcctgtccagctgctctgggtcaatctggtgacagacggc
ctgcctgccacggccctgggcttcaaccctcccgacctggacatcatgaacaaaccaccc
cggaacccgaaggagcccctgatcagcggatggctctttttccgttacctggccattggc
tgttacgttggcgcagctaccgtgggtgccgccgcgtggtggttcattgctgccgacgga
gggcccagggtgtccttctaccagctgagccacttcctacagtgtaaagatgacaacccg
gactttgaaggagtggattgtgcaatctttgagtccccatacccgatgacaatggcgctg
tctgttctagtaaccatagagatgtgtaacgccctcaacagcttgtccgaaaaccagtcc
ctgctgaggatgcccccctgggagaacatctggctcgtgggctccatctgcctgtccatg
tcgctccacttcctcatcctctacgtggaacctttgccacttattttccagatcacaccg
ctgaatctgacccagtggctgatggtgctgaaaatctccttgcctgtgattctgatggac
gagacgctcaagtttgtggcccgcaactacctggaacctggtaaagagtgtgtgcagcct
gccaccaagtcctgctcgctctcggcatgcaccgatgggatttcatggccgtttgtgctg
ctcataatgcccctggtggtctgggtctatagcacagacactaactttagtgatatgttc
tggtcttga
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