Mustela nigripes (black-footed ferret): 132023518
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Entry
132023518 CDS
T09425
Symbol
ROCK1
Name
(RefSeq) rho-associated protein kinase 1 isoform X1
KO
K04514
Rho-associated protein kinase 1 [EC:
2.7.11.39
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp04022
cGMP-PKG signaling pathway
mnp04024
cAMP signaling pathway
mnp04062
Chemokine signaling pathway
mnp04071
Sphingolipid signaling pathway
mnp04270
Vascular smooth muscle contraction
mnp04350
TGF-beta signaling pathway
mnp04360
Axon guidance
mnp04510
Focal adhesion
mnp04520
Adherens junction
mnp04530
Tight junction
mnp04611
Platelet activation
mnp04670
Leukocyte transendothelial migration
mnp04810
Regulation of actin cytoskeleton
mnp04921
Oxytocin signaling pathway
mnp05135
Yersinia infection
mnp05163
Human cytomegalovirus infection
mnp05200
Pathways in cancer
mnp05205
Proteoglycans in cancer
mnp05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
132023518 (ROCK1)
04071 Sphingolipid signaling pathway
132023518 (ROCK1)
04024 cAMP signaling pathway
132023518 (ROCK1)
04022 cGMP-PKG signaling pathway
132023518 (ROCK1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
132023518 (ROCK1)
04520 Adherens junction
132023518 (ROCK1)
04530 Tight junction
132023518 (ROCK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
132023518 (ROCK1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
132023518 (ROCK1)
04670 Leukocyte transendothelial migration
132023518 (ROCK1)
04062 Chemokine signaling pathway
132023518 (ROCK1)
09152 Endocrine system
04921 Oxytocin signaling pathway
132023518 (ROCK1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
132023518 (ROCK1)
09158 Development and regeneration
04360 Axon guidance
132023518 (ROCK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
132023518 (ROCK1)
05206 MicroRNAs in cancer
132023518 (ROCK1)
05205 Proteoglycans in cancer
132023518 (ROCK1)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
132023518 (ROCK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
132023518 (ROCK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mnp01001
]
132023518 (ROCK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mnp03036
]
132023518 (ROCK1)
Enzymes [BR:
mnp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
132023518 (ROCK1)
Protein kinases [BR:
mnp01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
132023518 (ROCK1)
Chromosome and associated proteins [BR:
mnp03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
132023518 (ROCK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH
C1_1
Pkinase_C
APH
Motif
Other DBs
NCBI-GeneID:
132023518
NCBI-ProteinID:
XP_059265294
LinkDB
All DBs
Position
8:complement(42266250..42414653)
Genome browser
AA seq
1355 aa
AA seq
DB search
MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYK
DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLSSANPNDNRSSPNV
DKSLQENLQKTIYKLEEQLHNEMQLKDEMEQKCRTSKIKLDKIMKELDEEGNQRRNLEST
VSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKL
AQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSVSQLESLNRELQERNRILENSKTQTD
KDYYQLQAVLEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDMLN
HSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKL
KEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTENKERMEDEVKNLSLQLEQES
NKRLLLQNELKTQAFEADNLKGQEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMR
ELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRESLKKIQELQSEKETLATQLDLAETKAE
SEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEETTSMLTKDIEVLRKENE
EITDKMRRAEEEYKLKKEEEISNLKAAFEKIINTERTLKTQAVNKLAEIMNRKDFKIDRK
KANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECAHKNELQMQL
ASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSIPNRGNIKRYGWKK
QYVVVSSKKILFYNDEQDKEQSSPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILY
ANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALE
CRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNP
PSGFVRASPRTLSTRSTANQSFRKAVKNTSGKTSS
NT seq
4068 nt
NT seq
+upstream
nt +downstream
nt
atgtcgactggggacagttttgagactcgatttgaaaaaatcgacaacctgctgcgggat
cccaaatcggaagtgaattcggattgtttgctggatggattggatgctttggtatatgat
ttggattttcctgccttaagaaaaaacaaaaatattgacaactttttaagcagatataaa
gacacaataaataaaattagagatttacgaatgaaagctgaagactatgaagtagtgaag
gtgattggtagaggtgcatttggagaagtacaattggtaagacataaatccaccaggaag
gtatatgctatgaagcttctcagtaaatttgaaatgattaagagatccgattctgctttt
ttctgggaagaaagggacatcatggcttttgctaacagcccttgggtcgtccagcttttt
tatgcattccaagatgatcgttatctctacatggtgatggagtacatgcctggtggagat
cttgtaaacttaatgagcaactatgatgtgcctgaaaaatgggcacgattctatactgca
gaagtagttcttgcattggatgcaatccattccatgggtttcattcatagagatgtgaaa
cctgataacatgctgctggataaatctggacatttgaagttagcagattttggtacttgt
atgaagatgaataaggaaggtatggtacgatgtgatacagcagttggaacacctgattac
atttcccctgaagtattaaaatctcaaggtggtgatggctattatggacgagaatgtgac
tggtggtcagttggggtatttttatatgaaatgcttgtaggtgatacacctttttatgca
gattctctggttggaacttacagtaagattatgaatcataaaaattcacttacctttcct
gatgataatgatatatcaaaagaagcaaaaaatcttatttgtgccttccttactgacaga
gaggtgagattagggcgaaatggtgttgaagaaatcaaacgacatctcttcttcaaaaat
gatcaatgggcttgggagacactcagagacactgtagcaccagttgtacctgatttaagt
agtgacattgatacaagtaattttgatgacttggaagaagataaaggagatgaagaaaca
ttccccatacctaaagcttttgttggcaatcaattaccttttgtaggatttacatattat
agcaatcgtagatacttatcttcagcaaatcctaatgataaccgaagtagccccaatgtg
gataaaagcttgcaggaaaatttgcaaaaaacaatttataagctggaagaacagctgcat
aatgaaatgcaattaaaagatgaaatggagcagaagtgcagaacttcaaagataaagcta
gacaagataatgaaagaattggatgaagaggggaatcaaagaagaaacctagaatctaca
gtttctcagattgagaaggagaaaatgttgctacagcatagaattaatgagtaccagaga
aaagcggaacaggaaaatgagaaaaggaggaatgtagaaaatgaagtttctacattaaag
gatcagttggaagacttaaagaaagtcagtcaaaattcacagcttgctaatgagaagctg
gcacaattacaaaagcagctagaagaagccaatgacttacttagaacagaatcagacaca
gctgtcagattaaggaagagtcacacagagatgagtaagtcagttagtcagctagagtcc
ctaaacagagaattgcaggagagaaatagaattttagagaattccaagacacagacggac
aaggactattaccagctgcaagctgtattagaagctgaacgaagagacagaggtcatgat
tctgagatgattggagaccttcaagctcgaattacatctttacaagaggaggtgaagcat
ctcaaacataatcttgaaagagtggaaggagaaagaaaagaagctcaagacatgcttaat
cactcagaaaaggaaaaaaataatttagagatagatttaaactataagcttaaatcatta
caacaacgtttagaacaagaggtaaatgaacataaagtaactaaagctcgtttaactgac
aaacatcaatctattgaagaggcaaagtctgttgcaatgtgtgaaatggaaaaaaagctg
aaggaagagagagaagctcgagagaaggctgaaaatagagttgttcagattgagaaacag
tgttcaatgctagatgttgatctgaaacaatctcagcagaagcttgagcatttgactgaa
aataaagaaaggatggaggatgaagttaagaatctgtcccttcaactggagcaggaatca
aacaagcggttgttattacagaatgaattgaagactcaagcatttgaagcagacaattta
aaaggtcaagaaaagcaaatgaaacaggaaataaatactttattggaagcaaagagatta
ttagaatttgaattagctcagcttacaaaacagtatagaggaaatgaaggacagatgcgg
gagctacaagatcagcttgaagctgagcaatatttctcgacactttataaaacccaggta
aaggaacttaaagaagaaattgaagaaaaaaacagagaaagtttaaagaaaattcaagaa
ctacaaagtgaaaaggaaactcttgctactcagctggatctagcagaaacaaaagctgag
tctgagcagttggctcgagggcttctagaagaacagtattttgaattaacccaagaaagc
aagaaagctgcttccagaaatagacaagagattacagataaagatcatactgttagtcgg
cttgaagaaacaaccagcatgttaaccaaagatattgaagtattaagaaaagaaaatgaa
gagataaccgataaaatgaggagggcagaggaggaatataaattgaagaaggaggaggag
atcagtaatcttaaggctgcctttgaaaagattatcaatacagaaagaacccttaaaacg
caggctgttaacaagttggcagaaataatgaatcggaaagattttaaaattgatagaaag
aaagctaatacacaggatttgagaaagaaggagaaggaaaatcgaaagctacaactggaa
ctcaaccaagaaagagagaaattcaaccagatggtagtgaaacatcagaaggaactgaat
gacatgcaggcgcaattggtagaagaatgtgcacataagaatgagcttcagatgcaattg
gctagcaaagagagtgatatagagcaattgcgtgctaaacttttggacctttcggattct
acaagtgttgctagttttcctagtgctgatgaaactgatggaaaccttccagagtcaaga
attgaaggttggctttcaataccaaatcgaggaaatatcaaacgatatggctggaagaag
cagtatgttgtggtgagcagcaaaaaaattttgttctataatgatgaacaagataaggaa
caatccagtccatccatggtattggatatagataaattgtttcacgttcgacctgtaacc
caaggagatgtttacagggctgaaactgaagaaattcctaaaatattccagatcctatat
gcaaatgaaggtgaatgtagaaaagatgtagagatggaaccagtacagcaagctgaaaag
actaattttcaaaaccacaaaggccatgagttcattcctacactctaccactttcctgcc
aactgtgaggcctgtgccaaacctctctggcatgtttttaagccacctcctgccctagaa
tgtcgaagatgccatgttaagtgccacagagatcacttagataagaaagaggacttaatt
tctccctgtaaagtaagttatgatgtaacatcagcaagagatatgctgctgttagcatgt
tctcaggatgaacaaaaaaaatgggtgacacatttggtaaagaaaatccctaagaatcca
ccatctggttttgttcgtgcatcccctcgaacactttctacaagatctactgcaaatcag
tctttccgaaaagcggtcaaaaatacatccggaaaaactagcagttaa
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integrated database retrieval system
