Mustela nigripes (black-footed ferret): 132024270
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Entry
132024270 CDS
T09425
Symbol
VAV2
Name
(RefSeq) guanine nucleotide exchange factor VAV2 isoform X1
KO
K05730
guanine nucleotide exchange factor VAV
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp04015
Rap1 signaling pathway
mnp04024
cAMP signaling pathway
mnp04062
Chemokine signaling pathway
mnp04510
Focal adhesion
mnp04650
Natural killer cell mediated cytotoxicity
mnp04660
T cell receptor signaling pathway
mnp04662
B cell receptor signaling pathway
mnp04664
Fc epsilon RI signaling pathway
mnp04666
Fc gamma R-mediated phagocytosis
mnp04670
Leukocyte transendothelial migration
mnp04810
Regulation of actin cytoskeleton
mnp05135
Yersinia infection
mnp05205
Proteoglycans in cancer
mnp05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
132024270 (VAV2)
04024 cAMP signaling pathway
132024270 (VAV2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
132024270 (VAV2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
132024270 (VAV2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
132024270 (VAV2)
04660 T cell receptor signaling pathway
132024270 (VAV2)
04662 B cell receptor signaling pathway
132024270 (VAV2)
04664 Fc epsilon RI signaling pathway
132024270 (VAV2)
04666 Fc gamma R-mediated phagocytosis
132024270 (VAV2)
04670 Leukocyte transendothelial migration
132024270 (VAV2)
04062 Chemokine signaling pathway
132024270 (VAV2)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
132024270 (VAV2)
09171 Infectious disease: bacterial
05135 Yersinia infection
132024270 (VAV2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
132024270 (VAV2)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
RhoGEF
SH3_2
SH3_1
SH3_9
SH2
SOS1_NGEF_PH
PH
C1_1
CH
CAMSAP_CH
RHG20_PH
SH2_2
PLU-1
C1_2
PH_10
Motif
Other DBs
NCBI-GeneID:
132024270
NCBI-ProteinID:
XP_059266368
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Position
9:2795542..2941762
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AA seq
834 aa
AA seq
DB search
MAGVAGVPAELGPSPSSPPGSLICHCHACPLRLSAISRVPRWRLSPCPDRCEISVGLGAS
QGQFLCLKNIRTFLKVCHDKFGLRNSELFDPFDLFDVRDFGKVISAVSRLSLHHVAQNKG
IRPFPSEETAENDDDVYRSLEELADEHDLGEDIYDCVPCEDEGDDIYEDIIKVEVRQPMK
MGMSEDDKRNCCLLEIQETEAKYYRTLEDIEKNYMTPLRQVLSPADVTAIFINLEDLIKV
HHSFLRAIDVSMMAGGSTLAKVFLDFKERLLIYGDYCSHMEHAQNTLNQLLAGREDVRQK
VEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSADRPERQQLREALEAMQDLA
MYINEVKRDKETLKKISEFQSSIENLQVKLEEYGRPKIDGELKVRSIVNHTKQDRYLFLF
DKVVIVCKRRGYSYELKEVIELLFHKMTDDPTNNKDVKKWSYGFYLIHLQGKQGFQFFCK
TEDMKRKWMEQFEMAMSNIKPDKANANHHSFQMYTFDKTTNCKACRMFLRGTFYQGYLCT
RCGVGAHKECLEVTPPCKISSPADLDASGAGPGPKMVAVQNYHGNPAPPGKPVLTFQTGD
VIELLRGDPESQWWEGRLVQTRKSGYFPSSSVKPCPVDGRPPVSRPPSRDIDYSAYPWFA
GNMERQQTDNLLKSHASGTYLIRERPAEAERFAISIKFHDEVKHIKVVEKDSWVHITEAK
KFENLLELVEYYQCHSLKESFKQLDTTLKYPYKSKERAASRASSRSPVFTPRVIGTAVAR
YNFAARDMRELSLREGDVVKIYSRIGGDQGWWKGEANGRIGWFPSTYVEEEGIQ
NT seq
2505 nt
NT seq
+upstream
nt +downstream
nt
atggctggtgtcgcgggcgtccccgcggagctggggccgtcaccctcctctccgcccggg
agcctgatttgtcactgccacgcctgcccgctgaggctttccgcgatttcacgtgtgccg
aggtggagactttcaccgtgtcccgaccgctgtgaaatcagcgtgggcctcggggcctcc
cagggacagttcctgtgcttgaagaacatccgcacgttcctgaaagtctgccacgacaaa
tttgggctgcgaaacagcgagctgtttgacccctttgacctctttgacgtccgggacttc
gggaaggtcatctctgccgtgtccagactctccctgcaccatgtggctcagaacaaagga
atcaggcccttcccctcggaggagacggcggagaacgacgatgacgtgtaccgcagcctg
gaggagctggcggacgagcatgacctcggggaggacatctacgactgcgtcccgtgcgag
gacgagggcgacgacatctacgaggacattatcaaggtggaggtgcggcagcccatgaaa
atgggcatgtctgaggatgacaagaggaactgctgcttgctggagatccaggagaccgag
gccaagtactaccggaccctggaggacatcgagaagaactacatgacgcccctgaggcag
gtgctgagcccggcagacgtgaccgccatcttcatcaacctggaggacctgatcaaggta
catcacagcttcctgcgggccattgacgtgtccatgatggcggggggcagcacgctggcc
aaggtcttcctcgatttcaaggaaaggctgctgatctacggggactactgcagccacatg
gagcacgcgcagaacacgctgaaccagctcctcgccggccgggaggacgtccggcagaag
gtcgaggaatgcacgctgaaggtccaggacgggaagtttaagcttcaagacctgctggtg
gtccccatgcagagggttctcaaataccacctcctcctgaaggaacttctgagccactcc
gccgatcggcccgagaggcagcagctcagagaagcgctggaggccatgcaggacttagcg
atgtacataaacgaagtgaagcgggacaaggagaccctgaagaaaatcagcgagttccag
agttctatagaaaacctgcaagtgaagctggaggagtatgggaggccgaagatcgacggg
gagctgaaggtccgctccatcgtgaaccacaccaagcaagacaggtacttgttcctgttc
gacaaggtggtcatcgtctgcaagaggagaggctacagctacgagctgaaggaggtcatc
gagctgctcttccacaagatgacggacgaccccacgaacaacaaggacgtcaagaagtgg
tcctacggcttctacctcattcacttgcaaggaaagcagggcttccagttcttctgcaag
acggaggacatgaagcggaagtggatggagcagttcgagatggccatgtccaacatcaag
ccagacaaagccaatgccaaccaccacagcttccagatgtacacgtttgacaagaccacc
aactgcaaagcctgtagaatgtttctcaggggcaccttctaccagggctacctgtgcacc
aggtgtggggtcggggcacacaaggagtgtctggaagtgacgcccccctgtaagatcagt
tcccctgcagacctggacgcctccggagcaggacctggtcccaagatggtggccgtgcag
aattaccacggcaacccagctcccccggggaagccggtgctgaccttccagacgggcgat
gtgattgagctgctgagaggcgaccctgagtctcagtggtgggagggtcggctggtgcaa
accaggaagtcgggctactttcctagctcatccgtgaagccctgccccgtggacggaagg
ccgcccgtcagccggccaccatcccgcgacatcgactatagcgcctacccctggtttgcg
ggtaacatggagaggcagcagacggacaacctgctcaagtcgcacgccagcgggacctac
ctgatcagggagcggccggccgaggcggagcgcttcgccatcagtatcaagttccatgac
gaggtgaagcacatcaaggtggtggagaaggacagctgggtccacatcacggaagcgaag
aagtttgaaaacctcttggagctggtggagtactatcagtgccactcactgaaggagagc
ttcaagcagctggacaccacgctcaagtacccctataagtccaaggagcgcgcggcctcc
agggcctccagccggtccccagtgttcacaccccgtgtcatcggcacggccgtggccagg
tacaacttcgctgcccgggacatgcgggagctctcgctgcgggagggcgacgtggtgaag
atctacagccgcattggcggagaccagggctggtggaagggcgaggccaacggacggatt
ggctggtttccttcgacgtacgtggaggaggagggcatccagtga
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